Cholesterol Modulates the Membrane- Disordering Effects of Beta-Amyloid Peptides in the Hippocampus: Specific Changes in Alzheimer’s Disease

2000 ◽  
Vol 11 (4) ◽  
pp. 181-186 ◽  
Author(s):  
G.P. Eckert ◽  
N.J. Cairns ◽  
A. Maras ◽  
W.F. Gattaz ◽  
W.E. Müller
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides

scholarly journals O1-11-04: PGlu-beta-amyloid peptides, highly abundant in Alzheimer's disease brain, are cytotoxic in vitro , in situ and in vivo

2013 ◽  
Vol 9 ◽  
pp. P152-P152
Author(s):  
Hans Demuth ◽  
Rico Eichentopf ◽  
Raik Rönicke ◽  
Klaus G. Reymann ◽  
Stephan Schilling
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides

Oxidized lipoproteins, beta amyloid peptides and alzheimer’s disease

2001 ◽  
Vol 3 (2) ◽  
pp. 167-178 ◽  
Author(s):  
Albert Y. Sun ◽  
Bozena Draczynska-Lusiak ◽  
Grace Y. Sun
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides ◽  
Oxidized Lipoproteins

P4-061: Distribution of beta-amyloid peptides in leptomeningeal amyloid deposits and cerebrospinal fluid in patients with Alzheimer's disease: A mirror image

2012 ◽  
Vol 8 (4S_Part_18) ◽  
pp. P655-P656
Author(s):  
Marcella Catania ◽  
Giuseppe Di Fede ◽  
Valentina Albertini ◽  
Luisa Benussi ◽  
Giuliano Binetti ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Beta Amyloid ◽  
Mirror Image ◽  
Amyloid Peptides ◽  
Amyloid Deposits

scholarly journals Beta Amyloid Peptides: Extracellular and Intracellular Mechanisms of Clearance in Alzheimer’s Disease

10.5772/64744 ◽  
2016 ◽  
Author(s):  
Luis F. Hernández-Zimbrón ◽  
Elisa Gorostieta-Salas ◽  
Mei-Li Díaz-Hung ◽  
Roxanna Pérez-Garmendia ◽  
Gohar Gevorkian ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides ◽  
Intracellular Mechanisms

scholarly journals Probable Reasons for Neuron Copper Deficiency in the Brain of Patients with Alzheimer’s Disease: The Complex Role of Amyloid

Inorganics ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 6
Author(s):  
Soghra Bagheri ◽  
Ali A. Saboury ◽  
Thomas Haertlé ◽  
Mauro Rongioletti ◽  
Luciano Saso
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neurodegenerative Disorder ◽  
Copper Ions ◽  
Senile Plaques ◽  
Beta Amyloid ◽  
Amyloid Peptide ◽  
Amyloid Peptides ◽  
Main Components ◽  
Copper Depletion

Alzheimer’s disease is a progressive neurodegenerative disorder that eventually leads the affected patients to die. The appearance of senile plaques in the brains of Alzheimer’s patients is known as a main symptom of this disease. The plaques consist of different components, and according to numerous reports, their main components include beta-amyloid peptide and transition metals such as copper. In this disease, metal dyshomeostasis leads the number of copper ions to simultaneously increase in the plaques and decrease in neurons. Copper ions are essential for proper brain functioning, and one of the possible mechanisms of neuronal death in Alzheimer’s disease is the copper depletion of neurons. However, the reason for the copper depletion is as yet unknown. Based on the available evidence, we suggest two possible reasons: the first is copper released from neurons (along with beta-amyloid peptides), which is deposited outside the neurons, and the second is the uptake of copper ions by activated microglia.

scholarly journals P2-060: Anti-aggregation effect of AA-peptide on beta-amyloid peptides in Alzheimer's disease

2013 ◽  
Vol 9 ◽  
pp. P364-P365
Author(s):  
Ge Bai ◽  
Haifan Wu ◽  
Yaqiong Li ◽  
Youhong Niu ◽  
Qiao Qiao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides ◽  
Aggregation Effect

scholarly journals Alzheimer's disease beta-amyloid peptides are released in association with exosomes

2006 ◽  
Vol 103 (30) ◽  
pp. 11172-11177 ◽  
Author(s):  
L. Rajendran ◽  
M. Honsho ◽  
T. R. Zahn ◽  
P. Keller ◽  
K. D. Geiger ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Beta Amyloid ◽  
Amyloid Peptides
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