Powdered Milk Micellar Casein Prevents Oral Colonization by Streptococcus sobrinus and Dental Caries in Rats: A Basis for the Caries–Protective Effect of Dairy Products

1999 ◽  
Vol 33 (6) ◽  
pp. 446-454 ◽  
Author(s):  
B. Guggenheim ◽  
R. Schmid ◽  
J-M. Aeschlimann ◽  
R. Berrocal ◽  
J.-R. Neeser
Keyword(s):  
Dental Caries ◽  
Protective Effect ◽  
Dairy Products ◽  
Streptococcus Sobrinus ◽  
Powdered Milk ◽  
Micellar Casein ◽  
Oral Colonization

scholarly journals Effect of probiotic fermented dairy products on incidence of respiratory tract infections: a systematic review and meta-analysis of randomized clinical trials

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Kamil Rashidi ◽  
Bahman Razi ◽  
Mina Darand ◽  
Azadeh Dehghani ◽  
Parisa Janmohammadi ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Protective Effect ◽  
Dairy Products ◽  
Respiratory Tract Infections ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Total Sample ◽  
Fermented Dairy Products ◽  
Tract Infections ◽  
Fermented Dairy

Abstract Background Previous studies have suggested that the consumption of probiotic fermented dairy products (PFDP) may have a protective effect on respiratory tract infections (RTIs). However, the results of studies are inconclusive. We aimed to systematically investigate the effect of PFDP on RTIs by performing a meta-analysis of randomized controlled trials (RCTs). Methods PubMed and Scopus databases were systematically searched up to October 2020 to identify eligible RCTs. Meta-analysis outcomes were risk of incidence of upper (URTIs ) and lower (LRTIs ) respiratory tract infections. A random-effects model was used to pool the relative risks (RR) and corresponding 95 % confidence intervals (CI) for outcomes following conception of PFDP. Results A total of 22 RCTs, with a total sample size of 10,190 participants, were included in this meta-analysis. Compared with placebo, consumption of PFDP had a significant protective effect against RTIs in the overall analysis (RR = 0.81, 95 %CI: 0.74 to 0.89) and in children (RR = 0.82, 95 %CI: 0.73 to 0.93), adults (RR = 0.81, 95 %CI: 0.66 to 1.00), and elderly population (RR = 0.78, 95 %CI: 0.61 to 0.98). The significant decreased risk of RTIs was also observed for URTIs (RR = 0.83, 95 %CI: 0.73 to 0.93), while, this effect was marginal for LRTIs (RR = 0.78, 95 %CI: 0.60 to 1.01, P = 0.06). The disease-specific analysis showed that PFDP have a protective effect on pneumonia (RR = 0.76, 95 %CI: 0.61 to 0.95) and common cold (RR = 0.68, 95 %CI: 0.49 to 0.96). Conclusions Consumption of PFDP is a potential dietary approach for the prevention of RTIs.

scholarly journals Biomarkers for Lifetime Caries-Free Status

2020 ◽  
Vol 11 (1) ◽  
pp. 23
Author(s):  
Ariana M. Kelly ◽  
Mariana Bezamat ◽  
Adriana Modesto ◽  
Alexandre R. Vieira
Keyword(s):  
Genetic Variation ◽  
Dental Caries ◽  
Protective Effect ◽  
Permanent Teeth ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Interacting Protein ◽  
Mandibular Molars ◽  
Matrix Metallopeptidase ◽  
Free Status

The purpose of this study was to address the hypothesis that extreme outcomes of dental caries, such as edentulism or prematurely losing permanent teeth are associated with genetic variation in enamel-formation genes. After scanning 6206 individuals, samples of 330 were selected for this study. Tested phenotypes included patients who were edentulous by age 30, patients with missing first molars by age 30, patients with missing second molars by age 30, and caries-free patients. Fourteen single nucleotide polymorphisms were genotyped by TaqMan chemistry. The analyses of each phenotype were performed using the software PLINK with an alpha of 0.05. Nominal associations were found between rs12640848 in enamelin (p = 0.05), rs1784418 in matrix metallopeptidase 20 (p = 0.02), and rs5997096 in the tuftelin interacting protein 11 and being caries-free at the age of 60. When combining patients that were missing both first mandibular molars and missing both second mandibular molars, no associations were found. Matrix metallopeptidase 20, and tuftelin interacting protein 11 also showed trends for association with being caries-free. Genetic variation in TFIP11, MMP20, and ENAM may have a protective effect increasing the chances of individuals preserving their teeth caries-free over a lifetime.

Studies on the Relation of Dairy Products to Dental Caries in Caries-Susceptible Rats

1959 ◽  
Vol 67 (2) ◽  
pp. 253-273 ◽  
Author(s):  
James H. Shaw ◽  
Barbara J. Ensfield ◽  
David H. Wollman
Keyword(s):  
Dental Caries ◽  
Dairy Products

scholarly journals DYNAMICS OF DAIRY PRODUCTS CONSUMPTION IN POLAND AGAINST THE BACKGROUND OF THE EU

2020 ◽  
Vol 56 (2) ◽  
Author(s):  
Piotr Bórawski ◽  
Mariola Grzybowska-Brzezińska ◽  
James Willam Dunn
Keyword(s):  
Dairy Products ◽  
Consumer Preferences ◽  
Skim Milk ◽  
Ice Cream ◽  
Powdered Milk ◽  
Milk Products ◽  
Average Consumption ◽  
Per Capita Consumption ◽  
Milk And Dairy Products ◽  
The Eu

Consumption is among the key determinants of milk production and profitability. The main purpose of this paper is to present the level of and changes in milk and dairy products consumption in the EU in 2004–2018. Due to changing consumer preferences, the average consumption of milk and milk products in EU countries is on an increase. In turn, Poland witnesses growth in consumption of milk for ripening and processed cheese and yogurt. In 2004–2017, per capita consumption of ice cream, cheese and powdered milk followed a downward trend. In order to examine changes in the consumption of milk and milk products, a forecast was prepared which shows that in 2018–2022, Poland will experience an increase in the average monthly consumption of milk, ice cream and cheese. On the other hand, the EU will report growth in consumption of fresh dairy products, butter, cheese, skim milk and powdered milk, and a decrease in casein consumption.

scholarly journals Dental Caries and Associated Risk Indicators among Married Saudi Women

2021 ◽  
Author(s):  
Syed Akhtar Hussain Bokhari ◽  
Kawthar Almumtin ◽  
Wala Mohammed Alhashiem ◽  
Duaa youssef Albandar ◽  
Zainab Nouh Alyahya ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Dental Caries ◽  
General Hospital ◽  
Dairy Products ◽  
Family Income ◽  
Dietary Habits ◽  
Risk Indicators ◽  
Dental Visits ◽  
Saudi Women ◽  
Number Of Children

Abstract Objective The aim of this study was to evaluate decayed, missing, and filled teeth (DMFT) experience among married females in Saudi Arabia and provide an exploratory data for subsequent primary prevention. Materials and Methods A cross-sectional quantitative study was conducted at a general hospital in Hofuf, Saudi Arabia. All married women attending the general hospital from March 1st to April 15th, 2021 were requested to participate. Data was collected on a validated self-reported questionnaire consisting of sociodemographic factors, medical history, dietary pattern, and DMFT. Descriptive and regression analyses were performed using p ≤0.050. Results Four hundred forty-eight married females with the mean age of 30.81 ± 6.11 years, mean duration of marriage of 9.55 ± 6.58 years, and having average number of children 2.32 ± 1.69 participated in the study. 61.7% mothers had ≥10 years of education. 63.6% were non-working and 56.5% were found with low family income. 66% participants reported of doing exercise less or more often yet 51.7% were ≥overweight. Consumption of energy drinks and dairy products was found significantly associated with increasing number of DMFT. Use of fluoridated toothpaste and dental visits was also found associated with increasing number of dental caries. Increasing age (p = 0.040), increasing number of children, and middle family income were also significantly associated with higher DMFT, respectively (p = 0.002, p = 0.022). In multi-logistic adjusted analysis, only consumption of dairy products, dental visits, and the unsure status of the use of fluoridated toothpaste were significantly associated with DMFT ≥1. Conclusion DMFT status in married Saudi women was associated with participants' dietary habits, oral health-related practices, family income, married years, and number of children.

scholarly journals The relationship between dairy products intake and breast cancer incidence: a meta-analysis of observational studies

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yujing He ◽  
Qinghua Tao ◽  
Feifei Zhou ◽  
Yuexiu Si ◽  
Rongrong Fu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Protective Effect ◽  
Dairy Products ◽  
Meta Analysis ◽  
Breast Cancer Incidence ◽  
Cochrane Library ◽  
Female Population ◽  
Fermented Dairy Products ◽  
Fermented Dairy ◽  
The Relationship

Abstract Background The effect of dairy products intake on breast cancer (BC) is highly controversial. This study aims to investigate the relationship between dairy intake and BC incidence. Methods A search was carried out in PubMed, EBSCO, Web of Science, and Cochrane Library databases before January 2021. The primary objective was the risk of BC and intake of dairy products were exposure variables. Results The meta-analysis comprised 36 articles with 1,019,232 participants. Total dairy products have a protective effect on female population (hazard ratio (HR) =0.95, 95% confidence interval (CI) =0.91–0.99, p = 0.019), especially for estrogen receptor-positive (ER+) (HR = 0.79, p = 0.002) and progesterone receptor-positive (PR+) BC (HR = 0.75, p = 0.027). For ER+/PR+ BC, there is a trend of protection, but it has not reached statistical significance (HR = 0.92, p = 0.075). Fermented dairy products can reduce BC risk in postmenopausal population (HR = 0.96, 95%CI = 0.93–0.99, p = 0.021), but have no protective effect on premenopausal population (HR = 0.98, 95%CI = 0.94–1.03, p = 0.52). Non-fermented dairy products have no significant effect on BC occurrence (p > 0.05). High-fat dairy products are harmful to women, without statistical difference (HR = 1.06, 95%CI = 1.00–1.13, p = 0.066). On the contrary, low-fat dairy products can protect the premenopausal population (HR = 0.94, 95%CI = 0.89–1.00, p = 0.048). Conclusion The intake of dairy products can overall reduce BC risk in the female population, but different dairy products have varying effects on different BC subtypes and menopausal status.

scholarly journals Longitudinal study of dental caries incidence associated with Streptococcus mutans and Streptococcus sobrinus in pre-school children

2005 ◽  
Vol 54 (7) ◽  
pp. 661-665 ◽  
Author(s):  
Mitsugi Okada ◽  
Yoshiko Soda ◽  
Fumiko Hayashi ◽  
Takako Doi ◽  
Junji Suzuki ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Dental Caries ◽  
Streptococcus Mutans ◽  
School Children ◽  
Streptococcus Sobrinus

Determination and Confirmation of Identity of Aflatoxin M1 in Dairy Products: Collaborative Study

1980 ◽  
Vol 63 (4) ◽  
pp. 907-921
Author(s):  
Robert D Stubblefield ◽  
Hans P Van Egmond ◽  
Walter E Paulsch ◽  
Pieter L Schuller ◽  
◽  
...  
Keyword(s):  
Dairy Products ◽  
Rapid Determination ◽  
Collaborative Study ◽  
Test Methods ◽  
Aflatoxin M1 ◽  
Powdered Milk ◽  
Limit Of Determination ◽  
Sample Extraction ◽  
Study Results ◽  
Derivatives Of

Abstract An international collaborative study involving 23 collaborators was conducted to test methods, improved over previous methods with respect to speed and solvent use, for the rapid determination and thin layer chromatographic (TLC) confirmation of aflatoxin M1 identity in dairy products. For the quantitative method, collaborators assayed samples of Couda and cheddar cheeses, powdered milk, and butter containing levels of M1 near the anticipated limit of determination. Statistical analysis of the study results indicated that the lower limit of determination and precision of this method were comparable to these parameters of methods previously approved for analysis for aflatoxin M1. A few collaborators found that M1 eluted early from cleanup columns with cheese and butter samples and that emulsions formed during powdered milk sample extraction. The reasons for these problems have been determined and remedies are provided. For the TLC confirmation of identity method, collaborators prepared trifluoroacetic acid derivatives of M1 on the plates after 2-dimensional development. Concentrations as low as 0.3 ng/g cheese and 1.0 ng/g powdered milk were determined in this study. As a result of this study, both methods have been adopted as official first action methods by the AOAC and as reference methods by IUPAC.

The Role of Genetic Factors in the Outbreak Mechanism of Dental Caries

2018 ◽  
Vol 42 (1) ◽  
pp. 32-36 ◽  
Author(s):  
Junko Shimomura-Kuroki ◽  
Tomoko Nashida ◽  
Yukio Miyagawa ◽  
Tsuneo Sekimoto
Keyword(s):  
Regression Analysis ◽  
Dental Caries ◽  
Multiple Regression Analysis ◽  
Candidate Genes ◽  
Multiple Regression ◽  
Permanent Teeth ◽  
Caries Experience ◽  
Nucleotide Polymorphisms ◽  
Streptococcus Sobrinus ◽  
Mucosal Cells

Objective: The aim of the present study was to investigate the relationships between cariogenic bacterial infection and single nucleotide polymorphisms (SNPs) in candidate genes associated with dental caries, and to explore the factors related to caries in children.Study design: Children aged 3 to 11 years were selected. Detection of cariogenic bacteria (Streptococcus mutans, Streptococcus oralis, Streptococcus sobrinus and Lactobacillus) from the plaque of each patient, and SNP analyses of five candidate genes (MBL2, TAS2R38, GLUT2, MMP13 and CA6) were performed using DNA isolated from buccal mucosal cells. The dental caries experience in primary and permanent teeth was determined using the decayed, missing and filled teeth (DMFT) index, and the effects of the observed factors on the DMFT value were analyzed by multiple regression analysis. Results: The results of the multiple regression analysis showed that the DMFT value significantly increased in the presence of S. mutans or S. sobrinus (p < 0.001), while the dmft/DMFT value decreased in the presence of nucleobase C in MBL2 (p < 0.05). Conclusion: These results suggest that the MBL2 gene is related to the pathogenesis of dental caries.

Influence of Desalivation in Rats on Incidence of Caries in Intact Cagemates

1988 ◽  
Vol 67 (10) ◽  
pp. 1316-1318 ◽  
Author(s):  
W.H. Bowen ◽  
K.M. Madison ◽  
S.K. Pearson
Keyword(s):  
Dental Caries ◽  
Smooth Surface ◽  
Intact Animal ◽  
Transmitted Disease ◽  
Sprague Dawley ◽  
Streptococcus Sobrinus ◽  
Sprague Dawley Rats ◽  
Salivary Function ◽  
Micro Organisms

The evidence that dental caries is an infectious and transmitted disease in rodents is unequivocal. However, the factors controlling the transmission of micro-organisms from one animal to another have not been extensively explored. Results from previous studies in our laboratory showed that desalivated animals became infected by Streptococcus sobrinus in a shorter period of time than did intact animals. Furthermore, an additional study in our laboratory showed that animals with intact salivary function caged with desalivated animals harbored more S. sobrinus immediately following establishment of infection than did intact animals housed with other intact animals. Therefore, it seemed appropriate to determine the influence on caries development of caging a desalivated animal with an intact animal. In this study, intact Sprague-Dawley rats were caged with desalivated animals; additional groups of intact animals were housed with chlorhexidine-treated animals that were either intact or desalivated. Although chlorhexidine suppressed both caries development and the level of infection by S. sobrinus, nevertheless, intact animals caged with desalivated animals invariably developed more caries than did intact animals housed with other intact animals. Treating intact animals with chlorhexidine did not affect caries scores in untreated intact cagemates. Overall, the results suggest that a highly acidogenic flora with enhanced virulence (including S. sobrinus) is selected in the desalivated animals; this flora is apparently readily transmitted to intact cagemates, leading to enhanced levels of smooth-surface caries.

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