In vitro Enamel and Cementum Fluoride Uptake from Three Fluoride–Containing Composites

1998 ◽  
Vol 32 (6) ◽  
pp. 463-469 ◽  
Author(s):  
K. Kawai ◽  
D. Tantbirojn ◽  
A.S. Kamalawat ◽  
T. Hasegawa ◽  
D.H. Retief
Keyword(s):  
1976 ◽  
Vol 10 (5) ◽  
pp. 370-378 ◽  
Author(s):  
E. Kirkegaard ◽  
I.J. Møller ◽  
Skov Jensen

1998 ◽  
Vol 33 (1) ◽  
pp. 88-90 ◽  
Author(s):  
J.J.M. Damen ◽  
M.J. Buijs ◽  
A.J.P. van Strijp ◽  
J.M. ten Cate

2010 ◽  
Vol 137 (4) ◽  
pp. 458.e1-458.e8 ◽  
Author(s):  
Evangelia Chatzistavrou ◽  
Theodore Eliades ◽  
Spiros Zinelis ◽  
Athanasios E. Athanasiou ◽  
George Eliades

2007 ◽  
Vol 8 (7) ◽  
pp. 1-10 ◽  
Author(s):  
Elias Casals ◽  
Tchilalo Boukpessi ◽  
Christina M. McQueen ◽  
Sandy L. Eversole ◽  
Robert V. Faller

Abstract Aim The aim of this in vitro study was to investigate fluoride uptake in human enamel after use of commercially available toothpastes containing different fluoride compounds, or combinations of fluoride actives formulated into a single product, as a means of determining the efficiency of each formula for delivering caries preventing fluoride to demineralized (caries active) enamel. Methods and Materials Four test dentifrices and two controls were assessed and placed in groups as follows: Group 1: Lacer® (Spain); Group 2: Positive control-USP Reference Standard 1100 ppm F; Group 3: Fluocaril® Bi-Fluoré 250 (France); Group 4: Colgate Fluor Active (Denmark); Group 5: Elmex® (France); and Group 6: A placebo (formulated the same as the USP Reference Standard toothpaste with the exception that it contained < 1 ppm F). Cores 3 mm in diameter were removed from erupted human enamel specimens (extracted by local oral surgeons for orthodontic reasons) and stored in 1% Thymol solution prior to use. They were ground and polished to remove the natural fluoride rich enamel layer, then exposed to a demineralization solution, and assessed for surface microhardness to enable randomization for use in the study. Each group of five specimens underwent a daily pH cycling procedure that involved exposure to pooled human saliva (refreshed three times daily). The groups were then exposed to dentifrice slurries four times daily for one minute per exposure and to a demineralization solution for three hours. The cycling procedure was repeated for five days. Specimens were again analyzed for surface microhardness and fluoride uptake upon completion of five days of treatment. Results Average surface hardness: Groups 2 and 3 showed a statistically significant greater (p<0.05) change indicating greater remineralization compared to all other groups. The average change was 23.45 for Group 2 and 22.65 for Group 3. All other groups had changes ranging from 4.25-8.62. No other statistically significant differences were observed between groups. Fluoride uptake results: Groups 2 and 3 showed statistically significantly greater fluoride uptake versus all other groups (p <0.05). Groups 1 and 5 were significantly different from Group 6. No other statistically significant differences were observed for either analysis. Conclusions Of the marketed products included in the study, the Fluocaril® Bi-Fluoré 250 product formulation provided both the highest level of fluoride uptake and mineralization to the demineralized enamel. The clinical significance of these in vitro results is the confirmation Fluocaril® Bi-Fluoré 250 is effective at remineralizing enamel caries lesions. Citation Casals E, Boukpessi T, McQueen CM, Eversole SL, Faller RV. Anticaries Potential of Commercial Dentifrices as Determined by Fluoridation and Remineralization Efficiency. J Contemp Dent Pract 2007 November; (8)7:001-010.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Frank C. Sun ◽  
E. Eric Engelman ◽  
James A. McGuire ◽  
Gabrielle Kosmoski ◽  
Lauren Carratello ◽  
...  

Objective. The objective of this research was to evaluate the caries control potential of a new fluoride mouthrinse that also contained antimicrobial agents and a biofilm disrupting agent using differentin vitromodels.Methods. Fourin vitrostudies were conducted to assess the performance of this three pronged approach to caries control: (1) traditional enamel fluoride uptake, (2) surface microhardness study using pH cycling model and subsequent fluoride uptake, (3) a salivary biofilm flow-through study to determine the anti-microbial activity, and (4) a single species biofilm model measuring effect on biofilm matrix disruption.Results. The data showed that a LISTERINE rinse with fluoride, essential oils and xylitol was superior in promoting enamel fluoride uptake and in enhancing antimicrobial activity over traditional commercially available fluoridated products. An increase of the surface microhardness was observed when the LISTERINE rinse was used in combination with fluoridated toothpaste versus the fluoridated toothpaste alone. Finally, it was demonstrated that xylitol solutions disrupted and reduced the biovolume of biofilm matrix of matureStreptococcus mutans.Conclusion. Thesein vitrostudies demonstrated that a fluoride mouthrinse with antimicrobial agent and biofilm matrix disrupting agent provided multifaceted and enhanced anti-caries efficacy by promoting remineralization, reducing acidogenic bacteria and disrupting biofilm matrix.


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