The Isolation of Actinomyces naeslundii from Sound Root Surfaces and Root Carious Lesions

1998 ◽  
Vol 32 (2) ◽  
pp. 100-106 ◽  
Author(s):  
S.R. Brailsford ◽  
E.J.R. Lynch ◽  
D. Beighton
Keyword(s):  
Actinomyces Naeslundii ◽  
Carious Lesions ◽  
Root Surfaces

scholarly journals Phenotypic and Genotypic Selection of Microbiota Surviving under Dental Restorations

2005 ◽  
Vol 71 (5) ◽  
pp. 2467-2472 ◽  
Author(s):  
J. S. Paddick ◽  
S. R. Brailsford ◽  
E. A. M. Kidd ◽  
D. Beighton
Keyword(s):  
Serum Proteins ◽  
Genotypic Diversity ◽  
Salivary Secretion ◽  
Dentinal Tubules ◽  
Actinomyces Naeslundii ◽  
Dental Restorations ◽  
Final Sample ◽  
Carious Lesions ◽  
Carious Dentine ◽  
Selection Of

ABSTRACT The effects of sealing infected carious dentine below dental restorations on the phenotypic and genotypic diversity of the surviving microbiota was investigated. It was hypothesized that the microbiota would be subject to nutrient limitation or nutrient simplification, as it would no longer have access to dietary components or salivary secretion for growth. The available nutrients would be limited primarily to serum proteins passing from the pulp through the patent dentinal tubules to the infected dentine. Ten lesions were treated, and infected dentine was sealed below dental restorations for approximately 5 months. Duplicate standardized samples of infected dentine were taken at baseline and after the removal of the restorations. The baseline microbiota were composed primarily of Lactobacillus spp., Streptococcus mutans, Streptococcus parasanguinis, Actinomyces israelii, and Actinomyces gerencseriae. None of these taxa were isolated among the microbiota of the dentine samples taken after 5 months, which consisted of only Actinomyces naeslundii, Streptococcus oralis, Streptococcus intermedius, and Streptococcus mitis. The microbiota of the final sample exhibited a significantly (P < 0.001) increased ability to produce glycosidic enzymes (sialidase, β-N-acetylglucosaminidase, and β-galactosidase), which liberate sugars from glycoproteins. The genotypic diversity of S. oralis and A. naeslundii was significantly (P = 0.002 and P = 0.001, respectively) reduced in the final samples. There was significantly (P < 0.001) greater genotypic diversity within these taxa between the pairs of dentine samples taken at baseline than was found in the 5-month samples, indicating that the dentine was more homogenous than it was at baseline. We propose that during the interval between placement of the restorations and their removal, the available nutrient, primarily serum proteins, or the relative simplicity and homogeneity of the nutrient supply significantly affected the surviving microbiota. The surviving microbiota was less complex, based on compositional, phenotypic, and genotypic analyses, than that isolated from carious lesions which were also exposed to salivary secretions and pH perturbations.

Cephalometric features of connective tissue dysplasia manifestation in children and adolescents

2020 ◽  
Vol 20 (3) ◽  
pp. 174-183 ◽  
Author(s):  
B. N. Davydov ◽  
D. A. Domenyuk ◽  
S. V. Dmitrienko ◽  
T. A. Kondratyeva ◽  
Yu. S. Harutyunyan
Keyword(s):  
Connective Tissue ◽  
Morphological Features ◽  
Short Branch ◽  
Lower Jaw ◽  
Carious Lesions ◽  
High Prevalence ◽  
Care Facilities ◽  
The Face ◽  
Connective Tissue Dysplasia ◽  
Brain Parts

Relevance. The high prevalence of dysplastic disorders involving connective tissue, and its negative effecton the development of dentoalveolar anomalies, carious and non-carious lesions of the teeth, periodontopathy, temporomandibular joint issues in the child population, lay the basis for improving diagnostics algorithms. Enhancing the already available standards is of greatest importance for children at the initial stages of diagnostics when evaluating the external signs of dysplastic disorders.Purpose – improving diagnostics algorithms for connective tissue dysplasia (CTD) in children in primary dental care facilities based on the evaluation of external phenotype signs and maxillofacial morphological features.Materials and methods. Depending on the external phenotype manifestations severity, as well as on laboratory, clinical and instrumental signs, the 92 children with CTD were divided into groups with mild, moderate and severe degrees of undifferentiated dysplasia. Gnathometric and biometric examinations of the maxillofacial area were performed through traditional methods, whereas the diagnosis was set following the generally accepted classifications. The diagnosis confirmation implied evaluation through cone beam computed imaging.Results. The nature and the intensity of morphofunctional disorders in the craniofacial structures (“small” stigmas) depend on the severity of connective tissue dysplastic disorders.Conclusions. The change direction vector in the facial and brain parts of cranium in children with CTD is aimed at increasing hypoplastic tendencies and dolichocephalia, proof to that being the following constitutional and morphological features: the prevalence of the vertical type of face skeleton growth over the horizontal and neutral ones; a convex face profile with a disproportionate general heights of the face skeleton; reduction of latitudinal with an increase in altitude facial parameters; a narrow short branch of the lower jaw; the upper jaw displaced downwards and forward; a decrease in the size of the apical basis of the lower dentition, the lower jaw body, as well as the height and width of the lower jaw branches. 

Laser Therapy Evaluation in Complications of Restorations by Total-Etch Technique

2018 ◽  
Vol 69 (4) ◽  
pp. 921-925
Author(s):  
Cristina Angela Ghiorghe ◽  
Andra Claudia Gamen ◽  
Tiberiu Tirca ◽  
Sorin Andrian ◽  
Anca Melian ◽  
...  
Keyword(s):  
Laser Treatment ◽  
Laser Therapy ◽  
Hybrid Composite ◽  
Study Groups ◽  
Composite Resins ◽  
Single Bond ◽  
Class Iii ◽  
Anterior Teeth ◽  
Carious Lesions ◽  
Etch And Rinse

The aim of this study was to evaluate the efficiency of laser therapy in post-operative sensitivity by Visual Analogue Scale (VAS) to the 57 patients after restoration with two different resins composite. In the first group (28 patients, 30 teeth) it was restored the cavity class I Black with micro-hybrid composite Filtek Z250 - Adper Single Bond (3M/ESPE). In the second group (29 patients, 30 teeth) it was restored the cavity class III Black with nano-hybrid composite Ceram X One Sphere Tec-Prime and Bond One (Etch&Rinse) (Dentsply). The restorative treatments were performed by the same practitioner on posterior and anterior teeth diagnosed with mid-sized chronic carious lesions. Total etch (etch and rinse) strategy of adhesion was used for both composite resins. The laser treatment was performed in 2 sessions at 48 hours and after 7 days, for both study groups using laser Whitening Lase II (DMC Dental). Mean scores for VAS indices decreased significantly at 48 hours and 7 days, following laser treatment for all the investigated parameters (materials, sex, age) (p [ 0.05).

scholarly journals Periodontal Antibodies and All-Cause and Cardiovascular Disease Mortality

2019 ◽  
Vol 99 (1) ◽  
pp. 51-59 ◽  
Author(s):  
J. Qi ◽  
Z. Zihang ◽  
J. Zhang ◽  
Y.M. Park ◽  
D. Shrestha ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Igg Antibody ◽  
Actinomyces Naeslundii ◽  
Health And Nutrition ◽  
Cox Proportional Hazard ◽  
Disease Mortality ◽  
All Cause Mortality ◽  
Yellow Orange ◽  
Cox Proportional Hazard Models ◽  
Cvd Mortality

Periodontitis is positively linked to cardiovascular disease (CVD), diabetes, cancer, and increased mortality. Empirically derived clusters of IgG antibodies against 19 selected periodontal microorganisms have been associated with hyperglycemia. We further investigated associations between these serum IgG antibody clusters and all-cause and CVD mortality in a representative US population. Participants free of CVD and cancer and aged ≥40 y at baseline ( N = 6,491) from the Third National Health and Nutrition Examination Survey (1988 to 1994) were followed up until December 31, 2011. Antibodies were categorized into 4 clusters: red-green, orange-red, yellow-orange, and orange-blue. Over a 23-y follow-up, 2,702 deaths occurred, including 810 CVD-related deaths. In fully adjusted Cox proportional hazard models, the red-green cluster was positively associated with all-cause mortality (tertile 3 vs. tertile 1: hazard ratio [HR] = 1.43, 95% CI = 1.08 to 1.90, P = 0.015). The yellow-orange cluster was inversely associated with all-cause mortality (tertile 3 vs. tertile 1: HR = 0.78, 95% CI = 0.63 to 0.97, P = 0.028) and CVD mortality (tertile 2 vs. tertile 1: HR = 0.57, 95% CI = 0.42 to 0.77, P = 0.005). The orange-blue cluster (composed of antibodies against Eubacterium nodatum and Actinomyces naeslundii) was inversely associated with all-cause mortality (tertile 3 vs. tertile 1: HR = 0.65, 95% CI = 0.55 to 0.78, P < 0.0001) and CVD mortality (tertile 3 vs. tertile 1: HR = 0.65, 95% CI = 0.47 to 0.88, P = 0.007). These antibodies could predict prognosis or be potential intervention targets to prevent systemic effects of periodontal disease if further studies establish a causal relationship.

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