Protein tyrosine phosphatase receptor type C polypeptide (PTPRC) on human chromosome band 1q31→q32 localizes with marker D1S4131 on a 610-kb yeast artificial chromosome

1999 ◽  
Vol 87 (3-4) ◽  
pp. 223-224
Author(s):  
L.K. Goff ◽  
S. van Soest ◽  
M. Timón ◽  
E. Tchilian ◽  
P.C.L. Beverley
Keyword(s):  
Human Chromosome ◽  
Protein Tyrosine Phosphatase ◽  
Yeast Artificial Chromosome ◽  
Tyrosine Phosphatase ◽  
Artificial Chromosome ◽  
Receptor Type ◽  
Chromosome Band ◽  
Protein Tyrosine ◽  
Type C ◽  
Human Chromosome Band

scholarly journals Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

2021 ◽  
pp. jclinpath-2020-206927
Author(s):  
Maryam Ahmed Al Barashdi ◽  
Ahlam Ali ◽  
Mary Frances McMullin ◽  
Ken Mills
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Protein Tyrosine Kinase ◽  
Biological Activities ◽  
Tyrosine Phosphatase ◽  
Cell Types ◽  
Receptor Type ◽  
Future Research ◽  
Protein Tyrosine ◽  
Type C ◽  
Almost All

The leucocyte common antigen, protein tyrosine phosphatase receptor type C (PTPRC), also known as CD45, is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes, and is an essential regulator of T and B cell antigen receptor-mediated activation. Disruption of the equilibrium between protein tyrosine kinase and phosphatase activity (from CD45 and others) can result in immunodeficiency, autoimmunity, or malignancy. CD45 is normally present on the cell surface, therefore it works upstream of a large signalling network which differs between cell types, and thus the effects of CD45 on these cells are also different. However, it is becoming clear that CD45 plays an essential role in the innate immune system and this is likely to be a key area for future research. In this review of PTPRC (CD45), its structure and biological activities as well as abnormal expression of CD45 in leukaemia and lymphoma will be discussed.

Protein Tyrosine Phosphatase Receptor Type C

2012 ◽  
pp. 1488-1488
Author(s):  
Dominique M. Donato ◽  
Steven K. Hanks ◽  
Kenneth A. Jacobson ◽  
M. P. Suresh Jayasekara ◽  
Zhan-Guo Gao ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Protein Tyrosine ◽  
Type C

Assignment of the human protein tyrosine phosphatase, receptor-type, zeta (PTPRZ) gene to chromosome band 7q31.3

1995 ◽  
Vol 70 (1-2) ◽  
pp. 52-54 ◽  
Author(s):  
T. Ariyama ◽  
K. Hasegawa ◽  
J. Inazawa ◽  
K. Mizuno ◽  
M. Ogimoto ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Human Protein ◽  
Receptor Type ◽  
Chromosome Band ◽  
Protein Tyrosine

Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population

2002 ◽  
Vol 328 (3) ◽  
pp. 325-327 ◽  
Author(s):  
Clara Ballerini ◽  
Eleonora Rosati ◽  
Marco Salvetti ◽  
Giovanni Ristori ◽  
Stefania Cannoni ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Gene Mutation ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Protein Tyrosine ◽  
Multiple Sclerosis Population ◽  
Type C ◽  
Exon 4 ◽  
Mutation Distribution
Sign in / Sign up

Export Citation Format

Share Document