Measurement of Cerebral Oxyhaemoglobin Saturation and Jugular Blood Flow in Term Healthy Newborn Infants by Near-Infrared Spectroscopy and Jugular Venous Occlusion

Neonatology ◽  
1998 ◽  
Vol 75 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Frederik F. Buchvald ◽  
Klaus Kesje ◽  
Gorm Greisen
1994 ◽  
Vol 76 (3) ◽  
pp. 1388-1393 ◽  
Author(s):  
R. A. De Blasi ◽  
M. Ferrari ◽  
A. Natali ◽  
G. Conti ◽  
A. Mega ◽  
...  

We applied near-infrared spectroscopy (NIRS) for the simultaneous measurement of forearm blood flow (FBF) and oxygen consumption (VO2) in the human by inducing a 50-mmHg venous occlusion. Eleven healthy subjects were studied both at rest and after hand exercise during vascular occlusion. FBF was also measured by strain-gauge plethysmography. FBF measured by NIRS was 1.9 +/- 0.8 ml.100 ml-1.min-1 at rest and 8.2 +/- 2.9 ml.100 ml-1.min-1 after hand exercise. These values showed a correlation (r = 0.94) with those obtained by the plethysmography. VO2 values were 4.6 +/- 1.3 microM O2 x 100 ml-1.min-1 at rest and 24.9 +/- 11.2 microM O2 x 100 ml-1.min-1 after hand exercise. The scatter of the FBF and VO2 values showed a good correlation between the two variables (r = 0.93). The results demonstrate that NIRS provides the particular advantage of obtaining the contemporary evaluation of blood flow and VO2, allowing correlation of these two variables by a single maneuver without discomfort for the subject.


1999 ◽  
Author(s):  
Lelia A. Paunescu ◽  
Claudia Casavola ◽  
Maria-Angela Franceschini ◽  
Sergio Fantini ◽  
Lew Winter ◽  
...  

1993 ◽  
Vol 75 (4) ◽  
pp. 1884-1889 ◽  
Author(s):  
A. D. Edwards ◽  
C. Richardson ◽  
P. van der Zee ◽  
C. Elwell ◽  
J. S. Wyatt ◽  
...  

A noninvasive method of measuring hemoglobin flow through an organ by near-infrared spectroscopy (NIRS) is described that allows blood flow to be calculated. The method is derived from the Fick principle and uses a small change in arterial oxyhemoglobin concentration (brought about by a change in the fractional inspired O2 concentration) as an intravascular tracer. Changes in deoxyhemoglobin and oxyhemoglobin concentrations are quantified by monitoring variations in the absorption of near-infrared light in the organ, thus providing a measure of tracer accumulation. The tracer input function is calculated from the change in arterial O2 saturation, measured by pulse oximetry. The method was used to determine hemoglobin flow in the forearms of six healthy young adults on 10 occasions. Forearm hemoglobin flow ranged from 22.5 to 82.6 mumol.l-1.min-1. Calculated forearm blood flow ranged from 1.01 to 4.01 ml.100 g-1.min-1. For comparison, forearm blood flow was measured by venous occlusion plethysmography, and the relation between flow calculated by NIRS (y) and plethysmography (x) was y = 0.93x + 0.30 (r2 = 0.95). The mean difference between the methods was 0.14 ml.100 g-1.min-1. The technique may be widely applicable.


The Lancet ◽  
1988 ◽  
Vol 332 (8614) ◽  
pp. 770-771 ◽  
Author(s):  
A.D Edwards ◽  
Clare Richardson ◽  
M Cope ◽  
J.S Wyatt ◽  
D.T Delpy ◽  
...  

1998 ◽  
Vol 43 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Jayesh Patel ◽  
Kyla Marks ◽  
Idris Roberts ◽  
Denis Azzopardi ◽  
Anthony David Edwards

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