p53 Polymorphism and Human Papillomavirus Infection in Hong Kong Women with Cervical Cancer

2000 ◽  
Vol 50 (1) ◽  
pp. 60-63 ◽  
Author(s):  
Y.F. Wong ◽  
T.K.H. Chung ◽  
T.H. Cheung ◽  
T. Nobori ◽  
G.M. Hampton ◽  
...  
Vaccine ◽  
2008 ◽  
Vol 26 ◽  
pp. M60-M70 ◽  
Author(s):  
Sun Kuie Tay ◽  
Hextan Y.S. Ngan ◽  
Tang-Yuan Chu ◽  
Annie N.Y. Cheung ◽  
Eng Hseon Tay

Author(s):  
Jacqueline M. Mills ◽  
Elizabeth A. Stier

In 1992 Lorincz et al. were the first to evaluate the clinicopathologic correlation with 11 recently identified human papillomavirus (HPV) genotypes: 31, 33, 35, 42, 43, 44, 45, 51, 52, 56, and 58. Using cervical samples from 8 studies that included specimens from 2627 women, HPV genotypes were categorized by the likelihood of association with grades of cervical neoplasia (from normal to cancer). These findings were the basis of the determination that (a) HPV causes cervical cancer, (b) detection of the cancer associated HPV genotypes could identify women at risk for cervical pre-cancer and cancer, and (c) a prophylactic HPV vaccine should include protection against (at least) HPV 16 and 18.


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