Evaluation of the Body Composition and Fat Distribution in Long-Term Users of Hormone Replacement Therapy

1999 ◽  
Vol 48 (1) ◽  
pp. 52-55 ◽  
Author(s):  
G. Perrone ◽  
Y. Liu ◽  
O. Capri ◽  
C. Critelli ◽  
F. Barillaro ◽  
...  
2002 ◽  
Vol 8 (4) ◽  
pp. 137-140 ◽  
Author(s):  
Morten B Sørensen

One of the major concerns of perimenopausal women is obesity—and for a good reason. Both general and abdominal obesity as well as loss of skeletal muscle (sarcopenia) are accelerated through the menopausal transition and lifestyle changes as well as sex hormone deficiency play important roles. Most well conducted clinical trials have demonstrated hormone replacement therapy induced reversal or at least impairment of menopausal changes in body composition and the common worry that it causes weight gain is unsubstantiated. Coaching of weight loss in obese individuals is often a frustrating task but is nevertheless of immense importance because of the health hazards of obesity. Through the climacteric period, short-term hormone replacement therapy, with or without androgens for preservation of muscle mass, might inhibit obesity and this is likely to boost motivation for introduction of more comprehensive and long-lasting initiatives linked to persistent weight loss and long-term health benefit.


2008 ◽  
Vol 16 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Mylène Aubertin-Leheudre ◽  
Eric D.B. Goulet ◽  
Isabelle J. Dionne

Hormone-replacement therapy (HRT) attenuates the menopause-associated alterations in body composition. It is not known, however, whether this effect is a result of a concomitant increase in energy expenditure. The authors examined whether women submitted to a long-term HRT treatment presented greater energy expenditure than women who had never used HRT. We compared 13 postmenopausal women using HRT (>1 yr) with 13 age- (±2 yr) and body-mass-index-matched (BMI; ±1.5kg/m2) postmenopausal women not using HRT. Resting energy expenditure (REE; indirect calorimetry), body composition, and daily (DEE) and physical activity (PAEE) energy expenditure (accelerometry) were obtained. Although BMI, fat mass, fat-free mass, DEE, and PAEE were similar between groups, the HRT group displayed a significantly greater REE than the no-HRT group (Δ +222 kcal/day). In conclusion, the authors observed that a long-term treatment with HRT is associated with a greater REE in postmenopausal women. These results need to be confirmed.


2015 ◽  
Vol 104 (3) ◽  
pp. e5-e6
Author(s):  
A.H. Bayer ◽  
K.N. Goldman ◽  
R. Mauricio ◽  
M.J. Nachtigall ◽  
F. Naftolin ◽  
...  

The Lancet ◽  
2003 ◽  
Vol 361 (9353) ◽  
pp. 254 ◽  
Author(s):  
Norman N Chan ◽  
Peter CY Tong ◽  
CC Chow ◽  
Juliana CN Chan

1991 ◽  
Vol 16 (4) ◽  
pp. 231-245 ◽  
Author(s):  
T. C. Hillard ◽  
S. Whitcroft ◽  
M. C. Ellerington ◽  
M. I. Whitehead

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