In vitro Responses of Gallbladder Muscle from Patients with Acalculous Biliary Pain

Digestion ◽  
2000 ◽  
Vol 61 (2) ◽  
pp. 140-144 ◽  
Author(s):  
Rosina Ahmed ◽  
Nigel C. Bird ◽  
Russell Chess-Williams ◽  
William E.G. Thomas ◽  
Alan G. Johnson
Keyword(s):  
Biliary Pain ◽  
Acalculous Biliary Pain

Acalculous biliary pain: Cholecystectomy alleviates symptoms in patients with abnormal cholescintigraphy

1991 ◽  
Vol 101 (3) ◽  
pp. 786-793 ◽  
Author(s):  
Lillian Yap ◽  
Allan George Wycherley ◽  
Arthur Durieu Morphett ◽  
James Toouli
Keyword(s):  
Biliary Pain ◽  
Acalculous Biliary Pain

Quantitative cholescintigraphy and bile abnormalities in patients with acalculous biliary pain

2004 ◽  
Vol 31 (8) ◽  
Author(s):  
Julio Ponce ◽  
Vicente Pons ◽  
Ram�n Sopena ◽  
Vicente Garrigues ◽  
Marta Ponce ◽  
...  
Keyword(s):  
Biliary Pain ◽  
Acalculous Biliary Pain

The effect of endoscopic sphincterotomy on the motility of the gallbladder and sphincter of Oddi in patients with acalculous biliary pain syndrome

2013 ◽  
Vol 154 (8) ◽  
pp. 306-313 ◽  
Author(s):  
Attila Szepes ◽  
Zsolt Dubravcsik ◽  
László Madácsy
Keyword(s):  
Ejection Fraction ◽  
Endoscopic Sphincterotomy ◽  
Pain Syndrome ◽  
Sphincter Of Oddi ◽  
Gallbladder Motility ◽  
Sphincter Of Oddi Dysfunction ◽  
Biliary Pain ◽  
Gallbladder Ejection Fraction ◽  
Oddi Dysfunction ◽  
Acalculous Biliary Pain

Introduction: Sphincter of Oddi dysfunction usually occurs after cholecystectomy, but it can sometimes be detected in patients with intact gallbladder too. The diagnostic value of the non-invasive functional tests is not established in this group of patients and the effects of sphincterotomy on transpapillary bile outflow and gallbladder motility are unknown. Aims: The aim of this study was to determine the effect of endoscopic sphincterotomy on the gallbladder ejection fraction, transpapillary bile outflow and the clinical symptoms of patients with acalculous biliary pain syndrome. Patients and methods: 36 patients with acalculous biliary pain syndrome underwent quantitative hepatobiliary scintigraphy, and all of them had decreased cholecytokinin-induced gallbladder ejection fraction. The endoscopic manometry of the sphincter of Oddi showed abnormal sphincter function in 26 patients who were enrolled the study. Before and after endoscopic sphincterotomy all patients had ultrasonographic measurement of cholecystokinin-induced gallbladder ejection fraction with and without nitroglycerin pretreatment and scintigraphy was repeated as well. The effects of sphincterotomy on gallbladder ejection fraction and transpapillary biliary outflow were evaluated. In addition, changes in biliary pain score with a previously validated questionnaire were also determined. Results: All 26 patients had decreased gallbladder ejection fraction before sphincterotomy measured with scintigraphy (19+18%) and ultrasound (16+9.7%), which was improved after nitroglycerin pretreatment (48.2+17%; p<0.005). Detected with both methods, the ejection fraction was in the normal range after sphincterotomy (52+37% and 40.8+16.5%), but nitroglycerin pretreatment failed to produce further improvement (48.67+22.2%, NS). Based on scintigraphic examination sphincterotomy significantly improved transpapillary biliary outflow (common bile duct half time 63±33 min vs. 37±17 min; p<0.05). According to results obtained from questionneries, 22 of the 26 patients gave an account of significant symptom improvement after sphincterotomy. Conclusions: Endoscopic sphincterotomy improves cholecystokinin-induced gallbladder ejection fraction, transpapillary biliary outflow as well as biliary symptoms in patients with acalculous biliary pain syndrome and sphincter of Oddi dysfunction. Cholecystokinin-induced gallbladder ejection fraction with nitroglycerin pretreatment, measured with ultrasonography can be useful to select a subgroup of patients who can benefit from sphincterotomy. Orv. Hetil., 2013, 154, 306–313.

Cholecystectomy Alleviates Acalculous Biliary Pain in Patients With a Reduced Gallbladder Ejection Fraction

1997 ◽  
Vol 90 (11) ◽  
pp. 1087-1090 ◽  
Author(s):  
RAJAN KHOSLA ◽  
AMOLAK SINGH ◽  
BRENT W. MIEDEMA ◽  
JOHN B. MARSHALL
Keyword(s):  
Ejection Fraction ◽  
Biliary Pain ◽  
Gallbladder Ejection Fraction ◽  
Acalculous Biliary Pain

Laparoscopic cholecystectomy: Effective treatment for chronic abdominal pain in children with acalculous biliary pain

2001 ◽  
Vol 36 (9) ◽  
pp. 1394-1396 ◽  
Author(s):  
Sonia Michail ◽  
Daniel Preud'Homme ◽  
Jeffery Christian ◽  
Victor Nanagas ◽  
Charles Goodwin ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Laparoscopic Cholecystectomy ◽  
Effective Treatment ◽  
Chronic Abdominal Pain ◽  
Biliary Pain ◽  
Acalculous Biliary Pain

Bethanechol provocation testing does not predict symptom relief after cholecystectomy for acalculous biliary pain

2004 ◽  
Vol 36 (10) ◽  
pp. 682-686 ◽  
Author(s):  
A. Smythe ◽  
R. Ahmed ◽  
M. Fitzhenry ◽  
A.G. Johnson ◽  
A.W. Majeed
Keyword(s):  
Symptom Relief ◽  
Biliary Pain ◽  
Provocation Testing ◽  
Acalculous Biliary Pain
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