Impact of Irritable Bowel Syndrome on Quality of Life and Resource Use in the United States and United Kingdom

Digestion ◽  
1999 ◽  
Vol 60 (1) ◽  
pp. 77-81 ◽  
Author(s):  
Beth A. Hahn ◽  
Songkai Yan ◽  
Scott Strassels
Keyword(s):  
Quality Of Life ◽  
United States ◽  
Irritable Bowel Syndrome ◽  
United Kingdom ◽  
Resource Use ◽  
The United States ◽  
Irritable Bowel

scholarly journals Cost-effectiveness of internet-delivered cognitive–behavioural therapy for adolescents with irritable bowel syndrome

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e023881 ◽  
Author(s):  
Filipa Sampaio ◽  
Marianne Bonnert ◽  
Ola Olén ◽  
Erik Hedman ◽  
Maria Lalouni ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Irritable Bowel Syndrome ◽  
Cost Effectiveness ◽  
Resource Use ◽  
Cost Effective ◽  
Behavioural Therapy ◽  
Cognitive Behavioural ◽  
The Difference ◽  
Irritable Bowel

ObjectiveTo assess whether exposure-based internet-delivered cognitive–behavioural therapy (internet-CBT) is a cost-effective treatment for adolescents with irritable bowel syndrome (IBS) compared with a waitlist control, from a societal perspective, based on data from a randomised trial.DesignWithin-trial cost-effectiveness analysis.SettingParticipants were recruited from the whole of Sweden via primary, secondary and tertiary care clinics reached through news media and advertising.ParticipantsAdolescents (aged 13–17) with a diagnosis of IBS.InterventionsParticipants were randomised to either an exposure-based internet-CBT, including 10 weekly modules for adolescents and five modules for parents, or a waitlist.Outcome measuresThe main health outcome was the quality-adjusted life-year (QALY) estimated by mapping Pediatric Quality-of-Life Inventory (PedsQL) scores onto EQ-5D-3L utilities. The secondary outcome was the point improvement on the PedsQL scale. Data on health outcomes and resource use were collected at baseline and 10 weeks post-treatment. Resource use was measured using the Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P) . Incremental cost-effectiveness ratios (ICER) were calculated as the difference in average costs by the difference in average outcomes between groups.ResultsThe base-case results showed that internet-CBT costs were on average US$170.24 (95% CI 63.14 to 315.04) more per participant than the waitlist. Adolescents in the internet-CBT group showed small QALY gains (0.0031; 95% CI 0.0003 to 0.0061), and an average improvement of 5.647 points (95% CI 1.82 to 9.46) on the PedsQL compared with the waitlist. Internet-CBT yielded an ICER of $54 916/QALY gained and a probability of cost-effectiveness of 74% given the Swedish willingness-to-pay threshold. The ICER for the outcome PedsQL was US$85.29/point improvement.ConclusionsOffering internet-CBT to adolescents with IBS improves health-related quality of life and generates small QALY gains at a higher cost than a waitlist control. Internet-CBT is thus likely to be cost-effective given the strong efficacy evidence, small QALY gains and low cost.Trial registration numberNCT02306369; Results.

Mo1642 Population Prevalence of Rome IV and Rome III Irritable Bowel Syndrome (IBS) in the United States (US), Canada and the United Kingdom (UK)

2016 ◽  
Vol 150 (4) ◽  
pp. S739-S740 ◽  
Author(s):  
Olafur S. Palsson ◽  
Miranda A. van Tilburg ◽  
Magnus Simren ◽  
Ami D. Sperber ◽  
William E. Whitehead
Keyword(s):  
United States ◽  
Irritable Bowel Syndrome ◽  
United Kingdom ◽  
The United States ◽  
The United Kingdom ◽  
Population Prevalence ◽  
Rome Iii ◽  
Irritable Bowel ◽  
Rome Iv

scholarly journals Quality of life in a new hospital hostel

1996 ◽  
Vol 20 (5) ◽  
pp. 275-276
Author(s):  
C. J. Simpson
Keyword(s):  
Quality Of Life ◽  
United States ◽  
United Kingdom ◽  
Inner City ◽  
Rural Community ◽  
The United States ◽  
City Area ◽  
The United Kingdom

Quality of life scores were measured In a new hospital hostel in a rural community. These scores were compared to scores on patients in a similar hospital hostel in an inner city area in the United Kingdom and also scores on patients living in a range of different facilities in the community In the United States.

scholarly journals A European Approach to Irritable Bowel Syndrome Management

1999 ◽  
Vol 13 (suppl a) ◽  
pp. 85A-88A ◽  
Author(s):  
Michel Delvaux ◽  
Jacques Frexinos
Keyword(s):  
United States ◽  
Irritable Bowel Syndrome ◽  
United Kingdom ◽  
The United States ◽  
Multiple Factors ◽  
Randomized Controlled ◽  
The United Kingdom ◽  
Number Of Patients ◽  
Irritable Bowel ◽  
Yearly Cost

Irritable bowel syndrome (IBS) is characterized by a number of clinical features and probably comprises a cluster of different conditions. The most frequent symptom reported by IBS patients is abdominal pain, although for a number of patients, bowel disturbances are the most prominent symptoms. Diarrhetic patients are seen in referral centres in continental Europe less frequently than in the United Kingdom or the United States. On the contrary, patients with constipation-prone IBS may comprise up to 80% of the IBS population referred to these centres. The pathophysiology of IBS is based on multiple factors. Most of the therapeutics proposed for the management of patients with IBS have been developed on the assumption that motility disorders of the gut are the most reliable pathological findings among these patients. Consequently, antispasmodics and motility regulatory agents have been widely used, alone or in association with intestinal adsorbents (clay-derived preparations), and laxatives or antidiarrhetic agents. Most of these drugs were developed several decades ago, and studies showing their efficacy have not reached the level of quality that is now required of randomized controlled trials. Therefore, following a complete and detailed review published in 1989, these drugs have not been used extensively in the United Kingdom or the United States. Large inquiries have also shown that the duration of prescription is quite different among countries. In European countries, maintenance therapy is frequently prescribed for several weeks to attempt to decrease the number of acute episodes. In contrast, psychotropic drugs are less popular among European gastroenterologists than among American gastroenterologists. However, multidisciplinary approaches to the treatment of these patients are frequent, and such drugs are often prescribed by home physicians. The results of large surveys estimated the yearly cost of such treatments to be around US$850. Patients with constipation and elderly patients with chronic disease receive more expensive treatments.

Hospitalization for severe skin disease improves quality of life in the United Kingdom and the United States: a comparative study

2003 ◽  
Vol 49 (2) ◽  
pp. 249-254 ◽  
Author(s):  
R.Sowjanya Ayyalaraju ◽  
Andrew Y Finlay ◽  
Peter J Dykes ◽  
Jennifer T Trent ◽  
Robert S Kirsner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
United States ◽  
United Kingdom ◽  
Comparative Study ◽  
Skin Disease ◽  
The United States ◽  
The United Kingdom
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