Outcome of Patients with Malignant Hypertension and End-Stage Renal Failure Treated by Long-Term Hemodialysis

Cardiology ◽  
1999 ◽  
Vol 92 (2) ◽  
pp. 93-98 ◽  
Author(s):  
José Jayme Galvão De Lima ◽  
João Américo da Fonseca ◽  
Anibal Godoy ◽  
Luis Aparecido Bortolotto ◽  
Eduardo M. Krieger
1989 ◽  
Vol 19 (4) ◽  
pp. 945-954 ◽  
Author(s):  
Ralph Shulman ◽  
John D. E. Price ◽  
John Spinelli

SYNOPSISAt ten-years follow-up of 64 haemodialysis patients, 43 had died and 21 were alive, twelve with cadaver renal transplants and nine on haemodialysis. Examination of the influence of psychological, demographic, physical and biochemical factors revealed the Beck Depression Inventory and age as the two most important predictors of survival. The behaviour of the patient was directly responsible for five (11·6%) of the deaths, by suicide in three cases and dietary noncompliance in two cases. Hypothetical mechanisms linking depression with reduced survival have been reviewed. As the impact of depression on survival was maximal in the first few years of dialysis, monitoring for depression should be incorporated into routine care from the start of dialysis together with evaluative interventions that might enhance survival.


1994 ◽  
Vol 17 (9) ◽  
pp. 457-460 ◽  
Author(s):  
K.N. Lai ◽  
A.Y.M. Wang

IgA nephropathy (IgAN) characterized by mesangial proliferative glomerulonephritis with predominant mesangial IgA deposition is the commonest glomerulonephritis worldwide. In contrast to the initial report indicated a favorable prognosis, subsequent reports have shown a highly variable outcome leading to end-stage renal failure (ESRF) in a significant proportion of patients. Many centers report a high incidence (ranging from 10-22%) of patients with idiopathic IgAN amongst the total population of patients on maintenance dialysis. Most of these patients develop ESRF at their middle-age and hence, will pose a significant and important workload in the dialysis and transplantation programme. Because IgAN is a disease with a variable rate of progression leading to chronic renal failure amongst younger patients and with neither effective nor specific treatment, identification of the clinical and pathologic prognostic indicators for these patients is of paramount importance in planning the long-term renal replacement program.


2002 ◽  
Vol 17 (4) ◽  
pp. 645-651 ◽  
Author(s):  
Jose Jayme G. De Lima ◽  
Marcelo Luis C. Vieira ◽  
Luis Fernando Viviani ◽  
Caio Jorge Medeiros ◽  
Luis Estevan Ianhez ◽  
...  

2020 ◽  
Vol 58 (11) ◽  
pp. 1941-1949
Author(s):  
Nick S. R. Lan ◽  
Lan T. Nguyen ◽  
Samuel D. Vasikaran ◽  
Catherine Wilson ◽  
Jacqueline Jonsson ◽  
...  

AbstractObjectivesHigh-sensitivity (hs) cardiac troponin (cTn) assays can quantitate small fluctuations in cTn concentration. Determining biological variation allows calculation of reference change values (RCV), to define significant changes. We assessed the short- and long-term biological variation of cardiac troponin I (cTnI) in healthy individuals and patients with renal failure requiring haemodialysis or cardiomyopathy.MethodsPlasma samples were collected hourly for 4 h and weekly for seven further weeks from 20 healthy individuals, 9 renal failure patients and 20 cardiomyopathy patients. Pre- and post-haemodialysis samples were collected weekly for 7 weeks. Samples were analysed using a hs-cTnI assay (Abbott Alinity ci-series). Within-subject biological variation (CVI), analytical variation (CVA) and between-subject biological variation (CVG) was used to calculate RCVs and index of individuality (II).ResultsFor healthy individuals, CVI, CVA, CVG, RCV and II values were 8.8, 14.0, 43.1, 45.8% and 0.38 respectively for short-term, and 41.4, 14.0, 25.8, 121.0% and 1.69 for long-term. For renal failure patients, these were 2.6, 5.8, 50.5, 17.6% and 0.30 respectively for short-term, and 19.1, 5.8, 11.2, 55.2% and 1.78 for long-term. For cardiomyopathy patients, these were 4.2, 10.0, 65.9, 30.0% and 0.16 respectively for short-term, and 17.5, 10.0, 63.1, 55.8% and 0.32 for long-term. Mean cTnI concentration was lower post-haemodialysis (15.2 vs. 17.8 ng/L, p < 0.0001), with a 16.9% mean relative change.ConclusionsThe biological variation of cTnI is similar between end-stage renal failure and cardiomyopathy patients, but proportionately greater in well-selected healthy individuals with very low baseline cTnI concentrations.


Nephron ◽  
1993 ◽  
Vol 65 (2) ◽  
pp. 249-253 ◽  
Author(s):  
Michael Barenbrock ◽  
Claus Spieker ◽  
Volker Laske ◽  
Peter Baumgart ◽  
Arnold P. G. Hoeks ◽  
...  

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