scholarly journals The Effects of Oxidative Stress in Urinary Tract Infection

2005 ◽  
Vol 2005 (4) ◽  
pp. 242-244 ◽  
Author(s):  
Ergul Belge Kurutas ◽  
Pınar Ciragil ◽  
Mustafa Gul ◽  
Metin Kilinc
PeerJ ◽  
2015 ◽  
Vol 3 ◽  
pp. e1363 ◽  
Author(s):  
Wael M. El-Deeb ◽  
Sébastien Buczinski

The present study aimed to investigate the diagnostic and prognostic importance of oxidative stress biomarkers and acute phase proteins in urinary tract infection (UTI) in camels. We describe the clinical, bacteriological and biochemical findings in 89 camels. Blood and urine samples from diseased (n= 74) and control camels (n= 15) were submitted to laboratory investigations. The urine analysis revealed high number of RBCS and pus cells. The concentrations of serum and erythrocytic malondialdehyde (sMDA & eMDA), Haptoglobin (Hp), serum amyloid A (SAA), Ceruloplasmin (Cp), fibrinogen (Fb), albumin, globulin and interleukin 6 (IL-6) were higher in diseased camels when compared to healthy ones. Catalase, super oxide dismutase and glutathione levels were lower in diseased camels when compared with control group. Forty one of 74 camels with UTI were successfully treated. The levels of malondialdehyde, catalase, super oxide dismutase, glutathione, Hp, SAA, Fb, total protein, globulin and IL-6 were associated with the odds of treatment failure. The MDA showed a great sensitivity (Se) and specificity (Sp) in predicting treatment failure (Se 85%/Sp 100%) as well as the SAA (Se 92%/Sp 87%) and globulin levels (Se 85%/Sp 100%) when using the cutoffs that maximizes the sum of Se + Sp. Multivariate logistic regression analysis revealed that two models had a high accuracy to predict failure with the first model including sex, sMDA and Hp as covariates (area under the receiver operating characteristic curve (AUC) = 0.92) and a second model using sex, SAA and Hp (AUC = 0.89). Conclusively, the oxidative stress biomarkers and acute phase proteins could be used as diagnostic and prognostic biomarkers in camel UTI management. Efforts should be forced to investigate such biomarkers in other species with UTI.


2005 ◽  
Vol 2005 (5) ◽  
pp. 309-311 ◽  
Author(s):  
Pinar Ciragil ◽  
Ergul Belge Kurutas ◽  
Mustafa Gul ◽  
Metin Kilinc ◽  
Murat Aral ◽  
...  

2017 ◽  
Vol 49 (12) ◽  
pp. 2105-2109
Author(s):  
Akin Soner Amasyali ◽  
Dilek Yilmaz ◽  
Mustafa Yilmaz ◽  
Faruk Kucukdurmaz ◽  
Ferah Sonmez ◽  
...  

2008 ◽  
Vol 81 (3) ◽  
pp. 312-315 ◽  
Author(s):  
Halil Ciftci ◽  
Ayhan Verit ◽  
Ercan Yeni ◽  
Murat Savas

2005 ◽  
Vol 206 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Mustafa Gul ◽  
Ergul Kurutas ◽  
Pinar Ciragil ◽  
Ali Cetinkaya ◽  
Metin Kilinc ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 22-23
Author(s):  
Shingo Minagawa ◽  
Chikara Ohyama ◽  
Shingo Hatakeyama ◽  
Kazunari Sato ◽  
Shigeru Sato ◽  
...  

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