scholarly journals Biological Role of Cobalt(II), Copper(II) and Nickel(II) Metal Ions on the Antibacterial Properties of Some Nicotinoyl-Hydrazine Derived Compounds

1997 ◽  
Vol 4 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Zahid H. Chohan ◽  
Syed K. A. Sherazi

Several cobalt(II), copper(II) and nickel(II) complexes of nicotinoylhydrazine-derived compounds were prepared and characterised by physical, spectral and analytical data. These compounds and their complexes have proven to be antibacterial. The screening data show the metal complexes to be more potential/bactericidal than the uncomplexed compounds against one or more bacterial species.

1999 ◽  
Vol 6 (2) ◽  
pp. 95-99 ◽  
Author(s):  
Zahid H. Chohan ◽  
M. Praveen

A number of biologically active complexes of cobalt(II) and nickel(II) with pyrazinedicarboxaimido derived thienyl and furanyl compounds having the same metal ion but different anions such as sulphate, nitrate, oxalate and acetate have been synthesized and characterized on the basis of their physical, spectral and analytical data. In order to evaluate the role of anions on their antibacterial properties, these ligands and their synthesized metal complexes with various anions have been screened against bacterial species Escherichia coil,Pseudomonas aeruginosa and Staphylococcus aureus. The title studies have proved a definitive role of anions in increasing the antibacterial properties.


1999 ◽  
Vol 6 (3) ◽  
pp. 187-192 ◽  
Author(s):  
Zahid H. Chohan

Biologically active nickel(ll), copper(ll) and zinc(ll) chelates with thiazole-derived nitro- and chlorosalicylaldehyde Schiff-bases having the same metal ion but different anions, e.g. nitrate, sulfate, oxalate and acetate have been synthesized and characterized on the basis of their physical, spectral and analytical data. In order to evaluate the possible participating role of anions on the antibacterial properties, these ligands and their synthesized metal chelates with various anions have been screened against bacterial species Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.


1997 ◽  
Vol 4 (6) ◽  
pp. 327-332 ◽  
Author(s):  
Zahid H. Chohan ◽  
S. K. A. Sherazi

Hydrazine derived compounds and its Co(II), Cu(II) and Ni(II) chelates having the same metal ion but different anions (e.g., nitrate, sulphate, oxalate and acetate) have been synthesised and characterised by their physical, spectral and analytical data. In order to evaluate the participating role of anions in the antibacterial activity, these synthesised ligands and its metal chelates have been screened against bacterial species such as Staphylococcus aureous, pseudomonas aeruginosa, Klebsiella pneumonae and Proteus vulgarus, and the results are reported.


2016 ◽  
Vol 18 (15) ◽  
pp. 10049-10058 ◽  
Author(s):  
Raewyn M. Town ◽  
Herman P. van Leeuwen

The drastic role of electrostatics in the binding of metal ions by soft charged nanoparticulate humic acid complexants is demonstrated.


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