scholarly journals Complexes With Biologically Active Ligands. Part 71 Synthesis and Fungitoxic Activity of Metal Complexes Containing 1,3,5-tris-(8-Hydroxyquinolino)- Trichlorocyclo-Triphosphazatriene

1996 ◽  
Vol 3 (5) ◽  
pp. 233-240 ◽  
Author(s):  
Mihai Barboiu ◽  
Cornelia Guran ◽  
Ioana Jitaru ◽  
Marilena Cimpoesu ◽  
Claudiu T. Supuran
Keyword(s):  
Electrical Conductivity ◽  
Ir Spectroscopy ◽  
Metal Complexes ◽  
General Formula ◽  
Elemental Analysis ◽  
Biologically Active ◽  
Conductivity Measurements ◽  
Candida Spp

Complexes containing 1,3,5-tris-(8-hydroxyquinolino)-trichlorocyclotriphosphazatriene, a new cyclophosphazene ligand, and Co(II), Cu(II) and Ni(II) were prepared. The new complexes, having the general formula [MLCl2], [ML2]Cl2, (M=Cu, Co, Ni); [NiLAc], [NiL2Ac]Ac and [ML3]X3 (M=Ni, Co, X=Cl, Ac) were characterised by elemental analysis, electronic-, IR spectroscopy, and electrical conductivity measurements. Some of them inhibited the growth of several fungi species (Aspergillus and Candida spp.)

scholarly journals Synthesis, Characterization and Thermal Studies of Fe(II), Co(II), Ni(II) and Cu(II) Complexes with bis-(4-benzylidenamino-phenyl)-methane Schiff base ligand

2021 ◽  
Vol 2063 (1) ◽  
pp. 012004
Author(s):  
Atared F. Hassan ◽  
Hiba H. Sabah ◽  
Afaq A. Turki
Keyword(s):  
Schiff Base ◽  
Metal Ions ◽  
General Formula ◽  
Elemental Analysis ◽  
Schiff Base Ligand ◽  
Thermal Studies ◽  
Molar Conductivity ◽  
Conductivity Measurements ◽  
Infra Red ◽  
Thermal Stable

Abstract A new series of Co(II), Fe(II), Cu(II) and Ni(II) complexes of Bis–(4-benzylidenamino-phenyl)-methane (L) have been prepared and characterized. The complexes conform to general formula [CoL(H2O)3] Cl2, [FeL(H2O)5]SO4.2H2O, [CuL(H2O)5] NO3 and [NiL(H2O)3Cl2], Infra red spectra and elemental analysis reveal uni-dentate coordination of Schiff base to metal ions. Molar conductivity measurements show that complexes (I, III) behave as 2:1 electrolyte while complex (II) behave as 1:1 electrolyte. The thermal studies for complexes shows that the complexes are thermal stable.

scholarly journals Complexes With Biologically Active Ligands. Part 111. Synthesis and Carbonic Anhydrase Inhibitory Activity of Metal Complexes of 4,5-Disubstituted-3-Mercapto-1,2,4-Triazole Derivatives

1998 ◽  
Vol 5 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Andrea Scozzafava ◽  
Christine Cavazza ◽  
Claudiu T. Supuran ◽  
Ioana Saramet ◽  
Fabrizio Briganti ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Nmr Spectroscopy ◽  
Animal Models ◽  
Carbonic Anhydrase ◽  
Metal Ions ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Inhibitory Activity ◽  
Biologically Active ◽  
Standard Procedures

Complexes containing five 4,5-disubstituted-3-mercapto-1,2,4-triazoles and Zn(II), Hg(II) and Cu(I) were synthesized and characterized by standard procedures (elemental analysis; IR, electronic and NMR spectroscopy, conductimetry and TG analysis). Both the thione as well as the thiolate forms of the ligands were evidenced to interact with the metal ions in the prepared complexes. The original mercaptans and their metal complexes behave as inhibitors of three carbonic anhydrase (CA) isozymes, CA I, II and IV, but did not lower intraocular pressure in rabbits in animal models of glaucoma.

scholarly journals 1,3,4-Thiadiazole Derivatives. Part 91. Synthesis and Biological Activity of Metal Complexes of 5-(2-Aminoethyl)-2-Amino-1,3,4-Thiadiazole

1996 ◽  
Vol 3 (5) ◽  
pp. 227-232 ◽  
Author(s):  
Mihai Barboiu ◽  
Marilena Cimpoesu ◽  
Cornelia Guran ◽  
Claudiu T. Supuran
Keyword(s):  
Biological Activity ◽  
Antifungal Activity ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Electronic Spectroscopy ◽  
Candida Spp ◽  
Thiadiazole Derivatives ◽  
In Vitro Antifungal Activity

Metal complexes of the title ligand (L) containing Co(II), Ni(II) and Cu(II) were prepared and characterized by elemental analysis, IR, electronic spectroscopy and conductimetry. The new derivatives, possessing the following formulae, CuL2(OH)2, NiL2Cl2, and [Co2LCl4]n showed in vitro antifungal activity against Aspergillus and Candida spp.

Metallkomplexe mit biologisch wichtigen Liganden, LXXVII. Synthese und Reaktionen von Dihydrido-Iridium(III)-Komplexen mit α-Aminocarboxylat-Liganden / Metal Complexes of Biologically Important Ligands, LXXVII. Synthesis and Reactions of Dihydrido-Iridium(III) Complexes of α-AminoCarboxylates

1995 ◽  
Vol 50 (2) ◽  
pp. 275-279 ◽  
Author(s):  
Kay Severin ◽  
Wolfgang Beck
Keyword(s):  
Ir Spectroscopy ◽  
Metal Complexes ◽  
General Formula

Dihydrido-iridium(III) complexes of the general formula IrH2(aa)(PPh3)2 (aa = L-alaninate, L-valinate, L-prolinate and L-phenylalaninate, 1 - 4 ) have been synthesized. Reactions of 1 - 3 with phenylacetylene give the hydrido-di(phenylethynyl) complex IrH(C≡CPh)2(PPh3)3 (5). The latter compound is also formed from IrH3(PPh3)3 and phenylacetylene. All complexes have been characterized by NMR (1H, 13C, 31P) and IR spectroscopy.

scholarly journals 8,18-Dithia-1,4,11,14-tetraazapentacyclo[11.7.0.03,11.05,9.015,19]icosa-3,5(9),6,13,15(19),16-hexaene-10,20-dione

Molbank ◽  
10.3390/m1056 ◽  
2019 ◽  
Vol 2019 (2) ◽  
pp. M1056
Author(s):  
Vladimir A. Ogurtsov ◽  
Oleg A. Rakitin
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Ir Spectroscopy ◽  
Elemental Analysis ◽  
13C Nmr ◽  
High Resolution Mass Spectrometry ◽  
Biologically Active ◽  
Active Compounds ◽  
Dimerization Product ◽  
Resolution Mass

4H-3λ2-Thieno[3,2-d]pyrimidin-4-one derivatives are of interest as biologically active compounds. In this communication, 2-(chloromethyl)-4H-3λ2-thieno[3,2-d]pyrimidin-4-one (1) was investigated in the reaction with ammonia, potassium phthalimide, and other basic agents. The dimerization product—8,18-dithia-1,4,11,14-tetrazapentacyclo[11.7.0.03,11.05,9.015,19]icosa-3,5(9),6,13,15(19),16-hexaene-10,20-dione was formed in the reaction with potassium phthalimide in DMF, by heating at 110 °C for 5 h. The structure of the newly synthesized compound was established by means of elemental analysis, high resolution mass-spectrometry, 1H, 13C NMR, and IR spectroscopy, and mass-spectrometry.

scholarly journals Complexes With Biologically Active Ligands. Part 91 Metal Complexes of 5-Benzoylamino- and 5-(3-Nitrobenzoyl-Amino)-1,3,4-Thiadiazole-2-Sulfonamide as Carbonic Anhydrase Inhibitors

1997 ◽  
Vol 4 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Andrei Jitianu ◽  
Marc A. llies ◽  
Fabrizio Briganti ◽  
Andrea Scozzafava ◽  
Claudiu T. Supuran
Keyword(s):  
Carbonic Anhydrase ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Epr Spectroscopy ◽  
Biologically Active ◽  
Carbonic Anhydrase Inhibitors ◽  
Standard Procedures

Complexes containing the anions of 5-benzoylamido-1,3,4-thiadiazole-2-sulfonamide and 5-(3-nitro-benzoylamido)-1,3,4-thiadiazole-2-sulfonamid as ligands, and V(IV); Cr(III); Fe(III); Co(II); Ni(II); Cu(II) and Ag(I) were synthesized and characterized by standard procedures (elemental analysis; IR, electronic, and EPR spectroscopy; TG, magnetic and conductimetric measurements). The original sulfonamides and their metal complexes are strong inhibitors of two carbonic anhydrase (CA) isozymes, CA I and II.

scholarly journals SYNTHESIS AND CHARACTERIZATION OF Mn(II), Ni(II), Fe(III), Co(III), Cu(II), Zn(II) AND Cd(II) COMPLEXES OF o-HYDROXYBENZOIC ACID HYDRAZIDE

2011 ◽  
Vol 19 (19) ◽  
pp. 35-58
Author(s):  
Vinnakota SRILALITHA ◽  
Aluru Raghavendra Guru PRASAD ◽  
Kakarla Raman KUMAR ◽  
Vahi SESHAGIRI ◽  
Laxmana Rao Krishna Rao RAVINDRANATH
Keyword(s):  
Electrical Conductivity ◽  
Elemental Analysis ◽  
Magnetic Moment ◽  
Acid Hydrazide ◽  
Synthesis And Characterization ◽  
Hydroxybenzoic Acid ◽  
Conductivity Measurements ◽  
Nmr Studies

A series of complexes of o-Hydroxybenzoic acid hydrazide (HBH) with Mn(II), Ni(II), Fe(III), Co(III), Cu(II), Zn(II), and Cd(II) was synthesized The stoichiometry and structures for the complexes have been established by elemental analysis, electrical conductivity measurements, magnetic moment measurements, and spectral (UV-Vis, IR, and NMR) studies.

scholarly journals Synthesis and Characterization of New Metal Complexes of α-Aminonitriles Derived from P- Toluidine and Aromatic Aldehydes

2010 ◽  
Vol 7 (3) ◽  
pp. 1214-1225
Author(s):  
Baghdad Science Journal
Keyword(s):  
Electrical Conductivity ◽  
Magnetic Susceptibility ◽  
Transition Metal ◽  
Metal Complexes ◽  
Aromatic Aldehydes ◽  
Transition Metal Ions ◽  
Synthesis And Characterization ◽  
Conductivity Measurements ◽  
Phenyl Acetonitrile

New metal complexes of some transition metal ions Co(II), Cu(II) , Cd(II) and Zn(II) were prepared by their reaction with previously prepared ligands HLI= (P-methyl anilino) phenyl acetonitrile and HLII = (P-methyl anilino) –P– chloro phenyl acetonitrile . The two ligands were prepared by Strecker’s procedure which includ the reaction of p- toluidine with benzaldehyde and P- chlorobenzaldehyde respectively. Structures were proposed depending on atomic absorption , i.r. and u.v.visible spectra in addition to magnetic susceptibility and electrical conductivity measurements.

scholarly journals Complexes With Biologically Active Ligands. Part 101 Inhibition of Carbonic Anhydrase Isozymes I and II With Metal Complexes of Imidazo[2,1−b]-1,3,4-Thiadiazole-2-Sulfonamide

1997 ◽  
Vol 4 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Andrea Scozzafava ◽  
Claudiu T. Supuran
Keyword(s):  
Carbonic Anhydrase ◽  
Metal Ions ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Epr Spectroscopy ◽  
Title Compound ◽  
Biologically Active ◽  
Standard Procedures

The title compound was prepared by an improved variant of the literature procedure, and metal complexes containing its anion and the following metal ions: Zn(II), Cd(II), Hg(II), Co(II), Ni(II), Cu(II), V(IV), Fe(III) and Ag(I) were synthesized and characterized by standard procedures (elemental analysis; IR, electronic, NMR and EPR spectroscopy; TG, magnetic and conductimetric measurements). The parent sulfonamide and its metal complexes are potent inhibitors of two carbonic anhydrase (CA) isozymes, CA I and II, and they might possess applications as selective cerebrovasodilating agents.

scholarly journals Synthesis and Characterization of a NewN"-[(1Z,2E)-2- (Hydroxyimino)-1-phenylpropylidene]-N"'-[(1E)-phenylmethylene]thiocarbonohydrazide and its Complexes with Co(II), Ni(II) and Cu(II)

2010 ◽  
Vol 7 (2) ◽  
pp. 409-418
Author(s):  
Dilip C. Sawant ◽  
A. Venkatchallam ◽  
R. G. Deshmukh
Keyword(s):  
Electrical Conductivity ◽  
Metal Ions ◽  
Metal Complexes ◽  
Magnetic Measurements ◽  
Divalent Metal ◽  
Synthesis And Characterization ◽  
Conductivity Measurements ◽  
Divalent Metal Ions ◽  
First Time

Synthesis and characterization of a newN"-[(1Z,2E)-2- (Hydroxyimino)-1-phenylpropylidene]-N"'-[(1E)-phenylmethylene]thiocarbonohydrazide and its metal complexes with Co(II), Ni(II) and Cu(II) metal ions. The ligand synthesis and characterization is reported for first time. The complexes of divalent metal ions were synthesized in 1:2 molar proportion using ethanol as solvent. The ligands as well as its metal complexes were characterized using various physicochemical techniques such as elemental analysis, spectral and magnetic measurements and electrical conductivity measurements in case of the metal complexes only. The data for the metal complexes reveals that they may be represented by ML2. The metal complexes show interesting features of coordination structure.

Sign in / Sign up

Export Citation Format

Share Document