scholarly journals Conservative Therapy for Nonspecific Granuloma of the Larynx Using a Beclomethasone Dipropionate Inhaler

1996 ◽  
Vol 3 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Masahiro Kawaida ◽  
Hiroyuki Fukuda ◽  
Yoshihisa Kawasaki ◽  
Akihiro Shiotani ◽  
Naoyuki Kohno

Nonspecific granuloma of the larynx is a benign tumor that usually occurs on the posterior glottis. Conventional treatment for this laryngeal lesion has consisted of surgical resection. However, this lesion has a strong tendency to recur postoperatively and may require multiple repeated operative procedures. Conservative treatment, consisting mainly of beclomethasone dipropionate inhalation therapy, was instituted in 20 cases with good results. We discussed the effect of beclomethasone dipropionate on this lesion as well as the etiology of this disease.

2010 ◽  
Vol 13 (4) ◽  
pp. 63-68 ◽  
Author(s):  
Alla Yur'evna Tokmakova ◽  
Lyudmila Petrovna Doronina ◽  
Galina Yur'evna Strakhova

Current trends in conservative therapy of chronic wounds associated with diabetes mellitus are discussed along with results of original studies aimedto assess efficacy of different methods for unloading the affected leg in patients with the neuropathic form of diabetic foot syndrome and diabeticnephropathy. Effects of collagen-containing dressings on the wound-related factors (matrix metalloproteinases 2 and 9, collagenolytic activity) andwound epithelization rate are described.


2021 ◽  
Vol 20 (1) ◽  
pp. 56-60
Author(s):  
G. I. Markov ◽  
◽  
A. L. Klochikhin ◽  
V. A. Romanov ◽  
M. G. Markov ◽  
...  

The aim of this work is to draw the attention of otorhinolaryngologists to the advantages of early conservative treatment of children with hypertrophy of the nasopharyngeal tonsil - adenoids. In childhood, a significant part of the protective and informational functions lies on the pharyngeal tonsil, since it is in the path of inhaled air. Unfavourable environmental conditions exacerbate its functional failure. Pathology of the lymphopharyngeal ring is highly prevalent and occupies a leading place among ENT diseases in children. Each person has a certain own microflora on the nasal mucosa from birth. In most cases, monoflora is determined on the mucous membrane of the nasal cavity, and only 2-3% is due to the combination of two types of microbial and fungal flora. For more than twenty years, we have been using the tactics of a sparing effect on the mucous membrane when using medicinal mixtures on a protective basis. Conservative treatment of 245 children aged 3 to 6 years with grade 1 – 2 adenoiditis was carried out, which made it possible to avoid surgical intervention in this group of children. When choosing a drug mixture, the sensitivity of the microflora of the patient’s nasal cavity was considered according to the results of a smear from the mucous membrane. Adenoidectomy is an operation with potentially undesirable consequences for the whole body, therefore, effective timely conservative therapy can reduce the risks and harms of surgery for pediatric patients.


2021 ◽  
Vol 9 (3) ◽  
pp. 269-271
Author(s):  
Wu Shun Felix Wong

Uterine lipoleiomyoma is a rare benign tumor of the uterus. Imaging has an important role in determining its intrauterine location and fatty nature. The diagnosis in this lady was made only by chance pathological findings postoperatively. This tumor has been reported because of its rarity. Our aim to present this case is to raise clinical awareness of this tumor, then conservative treatment or noninvasive surgery can be offered.


BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e017233 ◽  
Author(s):  
Timme MAJ van Vuuren ◽  
Jorinde H H van Laanen ◽  
Maaike de Geus ◽  
Patty J Nelemans ◽  
Rick de Graaf ◽  
...  

IntroductionDeep venous obstruction (DVO) has a great impact on quality of life (QoL) comparable to angina pectoris or chronic pulmonary disease. Post-thrombotic scar formation and May-Thurner syndrome (MTS) are the most common causes of DVO. Conventional treatment of DVO focuses on reducing pain or leg swelling by use of (pain) medication and therapeutic elastic stockings. In the past, a venous bypass was offered in severe post-thrombotic cases, but this procedure showed bad clinical and patency outcomes. With the introduction of percutaneous angioplasty and dedicated venous stents new opportunities were created. Deep venous stenting has been shown to be effective in retrospective case series. However, there is no prior research in which QoL after interventional treatment is compared with QoL after conventional treatment. Currently, there is a debate about the true additional value of interventional treatment. We investigate whether those patients who are treated with stenting experience a change in short form 36 (SF-36) and the Veines-QoL/Sym questionnaires compared with conventionally treated patients.Methods and analysisThis is a randomised trial comparing conservative deep venous management to interventional treatment. A total of 130 patients with post-thrombotic syndrome (PTS) or MTS, eligible for interventional percutaneous treatment, who did not have previous deep venous intervention will be included. Patients will be randomised to conservative treatment or venous stenting and stratified for the PTS or MTS subgroup. Conservative treatment consists of either one or a combination of pain medications, manual lymphatic drainage, compression stockings and regular post-thrombotic anticoagulant therapy.The primary outcome is the QoL change after 12 months compared with baseline QoL. Secondary outcomes are QoL changes at 6 weeks, clinical assessment of DVO, recurrence rate of deep venous thrombosis at 6 weeks and 12 months, and the total amount of working days lost. Intervention-specific outcomes include complications and patency.Ethics and disseminationThe protocol is approved by the Medical Ethics Committee of Academisch ziekenhuis Maastricht/Universiteit Maastricht, The Netherlands (protocol number NLNL55641.068.15 / METC 161008).We aim to publish the results of this study in a peer reviewed journal and present our findings at national or international conferences.Trial registration numberThe study protocol was registered atwww.clinicaltrials.gov(registration number:NCT03026049) on 17 January 2017.


2021 ◽  
Author(s):  
Shazia Rafiq ◽  
Hamayun Zafar ◽  
Prof. Dr. Syed Amir Gillani ◽  
Muhammad Sharif Waqas ◽  
Amna Zia ◽  
...  

Abstract Background: Cervical Radiculopathy (CR) is a disorder of the spinal nerve roots that is largely caused by space occupying lesion which can lead to nerve root inflammation and patient usually presents with radiating pain in his/her upper extremity known as cervical radiculopathy. The objective of the study was to compare the effectiveness of neural mobilization technique with conservative treatment on pain intensity, range of motion and disability.Methods: It was a double blinded randomized clinical trial; data was collected from Mayo Hospital, Lahore through convenience sampling technique. After taking consent from the patients, the patients fulfilling the inclusion and exclusion criteria were selected and randomized blindly and assigned through computer generated random number into two groups i.e. group 1 (neural mobilization), group 2 (conventional treatment). Pain intensity was measured on Numeric pain rating scale, range of motion measured with inclinometer and functional status with neck disability index (NDI). Data was analyzed using SPSS and difference in improvement before, after 02 and 04 weeks was noted and compared. Results: There was significant improvement in pain relief, neck disability and cervical ranges after the treatment in both groups compared to the pre-treatment status (p < 0.00) and when neural mobilization was compared , it was more effective technique than conventional treatment in reducing pain and neck disability (p < 0.00). But there was not statistical difference in mean score of cervical range of motion (p>0.05)Conclusions: The present study concluded that both neural mobilization and conservative treatment were effective as an exercise program for patient with cervical radiculopathy, however neural mobilization was more effective in reducing pain and neck disability in cervical radiculopathy.Trial registration: RCT20190325043109N1


2013 ◽  
Vol 10 (6) ◽  
pp. 41-50
Author(s):  
S N Avdeev

Beclomethasone dipropionate (BDP, Clenil UDV) is a well-studied inhaled corticosteroid for the treatment of patients with bronchial asthma (BA). Randomized controlled trials have shown that nebulized therapy with BDP was similar in its efficacy and safety to inhalation therapy with budesonide or fluticasone. Preferred patients for the treatment with nebulized BDP are elderly patients with asthma, unable to correctly perform inhalation with portable devices, patients with steroid-dependent asthma, and patients with a temporary loss of asthma control.


2014 ◽  
Vol 2 (2) ◽  
pp. 55-62 ◽  
Author(s):  
Sergei Fyodorovich Batkin ◽  
Olga Evgenievna Agranovich ◽  
Dmitry Borisovich Barsukov

Hip dislocation is common in patients with arthrogryposis and is observed in 13.5-58 % of cases. Currently, there is no conventional treatment strategy of this pathology. The review analyzes the data of the national and international literature on the etiopathogenesis, clinical picture and classifications, surgical and conservative treatment of this pathology.


Author(s):  
Viktor Janz ◽  
Georgi Wassilew ◽  
Michael Putzier ◽  
Geraldine Kath ◽  
Carsten Perka

IntroductionAfter a first-time total hip arthroplasty (THA) dislocation, a closed reduction followed by partial immobilization in an abduction brace is the recommended therapy. Despite modern abduction braces the success rate of conservative therapy is limited and evidence is scarce. The aim of this study was to identify risk factors for failure of conservative treatment after THA dislocation.Material and methodsEighty-seven patients, with conservative treatment of a first-time dislocation of a primary or revision THA, were included in this retrospective cohort study. Success was defined as a stable THA for a minimum of six months. Re-dislocation, open reduction or revision was defined as failure. The following risk factors were analyzed: gender, age, body mass index (BMI), ASA (American Society of Anesthesiologists) score, time of dislocation, head size, cup orientation, leg length, center of rotation and offset.ResultsSixty-seven percent of all patients experienced a re-dislocation, despite standardized conservative therapy. A BMI ≥ 25, early THA dislocation, and low cup anteversion were associated with a statistically significantly higher risk for re-dislocation. None of the other risk-factors achieved statistical significance. A multifactorial risk-factor analysis was performed to assess whether a cup position outside of Lewinnek’s safe zone in combination with gender, BMI and time to dislocation showed statistical significance for re-dislocation. Both BMI ≥ 25 and early dislocation showed a statistically higher failure rate. Cup position and gender were not significant.ConclusionsBMI ≥ 25, early THA dislocation and low cup anteversion were identified as significant risk factors for failure of conservative treatment with an abduction brace for first-time THA dislocation.


1995 ◽  
Vol 44 (2) ◽  
pp. 89-92
Author(s):  
Yoshiaki WATANABE ◽  
Masahiro OGAWA ◽  
Hitoshi TANAKA ◽  
Hitoshi KANAYAMA ◽  
Hiroshi SANO ◽  
...  

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