scholarly journals Study on the Effect of Deep Eutectic Solvent Liquid Phase Microextraction on Quality Standard, Antitussive, and Expectorant of Sangbaipi Decoction

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Lijing Li ◽  
Yuejie Wang ◽  
Fangxin Liu ◽  
Yang Xu ◽  
Huiwei Bao
Keyword(s):  
Liquid Phase ◽  
Extraction Method ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Quality Standard ◽  
Molar Ratio ◽  
Phenol Red ◽  
Liquid Ratio ◽  
Liquid Phase Microextraction ◽  
Low Efficiency

The SD was extracted with a new green eutectic solvent, and the extraction method of TCM decoction was developed. In the quantitative analysis by HPLC, choline chloride phenol was selected as the eutectic solvent, THF was used as the extractant, and investigation of DES type, DES molar ratio, DES-to-THF ratio, vortex time, and material-to-liquid ratio was carried out. The experimental results showed that the optimal extraction method was as follows: the molar ratio of DES was 1 : 3, and the material-liquid ratio was 5 : 1200 (mL/μL). The volume ratio of DES to THF was 1200 : 800 (μL), the vortex time was 3 min, and the extraction was repeated two times. The eutectic solvent liquid phase microextraction method was adopted to optimize the extraction method of SD and reduce the complicated processing, long time, and low efficiency of traditional methods. At the same time, in the mouse ammonia water inducing cough and phenol red excretion and expectorant experiments, SD high- and medium-dose groups have a significant inhibitory effect on the frequency of antitussive in mice and both can increase the excretion of phenol red to varying degrees, indicating that SD has good cough-relieving and expectorant effect. The present study suggests a scientific basis and basis for the clinical research and quality standard formulation of SD.

scholarly journals Development of a liquid-phase microextraction based on the freezing of a deep eutectic solvent followed by HPLC-UV for sensitive determination of common pesticides in environmental water samples

RSC Advances ◽  
2018 ◽  
Vol 8 (21) ◽  
pp. 11412-11418 ◽  
Author(s):  
Meghdad Pirsaheb ◽  
Nazir Fattahi
Keyword(s):  
Liquid Phase ◽  
Water Samples ◽  
Extraction Method ◽  
Deep Eutectic Solvent ◽  
Environmental Water ◽  
Environmental Water Samples ◽  
Liquid Phase Microextraction ◽  
Pesticides In Water ◽  
Sensitive Determination

In this research, a new extraction method based on liquid-phase microextraction and the freezing of deep eutectic solvent has been developed for the determination of pesticides in water prior to their analysis by HPLC-UV.

scholarly journals A green extraction design for enhancing flavonoid compounds from Ixora javanica flowers using a deep eutectic solvent

2020 ◽  
Vol 7 (10) ◽  
pp. 201116
Author(s):  
Nina Dewi Oktaviyanti ◽  
Kartini Kartini ◽  
Mochammad Arbi Hadiyat ◽  
Ellen Rachmawati ◽  
Andre Chandra Wijaya ◽  
...  
Keyword(s):  
Extraction Method ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Extraction Process ◽  
Raw Material ◽  
Molar Ratio ◽  
Flavonoid Compound ◽  
Total Flavonoids ◽  
Green Extraction ◽  
Optimum Extraction

In this study, an environmentally friendly extraction method for flavonoid compound from Ixora javanica , as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effects of any extraction parameters on flavonoid yields from the I. javanica flower. The extraction process was performed using deep eutectic solvent (DES) (choline chloride and propylene glycol at molar ratio of 1 : 1) and the ultrasound-assisted extraction method. Both single-factor and response surface analyses using three-level and three-factor Box Behnken designs were conducted to obtain the optimum flavonoid concentrations. The results showed that the optimum extraction conditions for total flavonoids featured an extraction time of 40 min, 25% water content in DES and a solid-to-liquid ratio of 1 : 25 g ml −1 . An extract obtained under optimum extraction conditions showed higher total flavonoid yields than an ethanolic extract which was used for comparison. Scanning electron microscope images demonstrated that both of the solvents also showed different effects on the outer surface of the I. javanica flower during the extraction process. In summary, our work succeeded in determining the optimum conditions for total flavonoids in the I. javanica flower using a green extraction method.

Application of Deep Eutectic Solvent (DES) as a Reaction Media for the Esterification of Acrylic Acid with n-Butanol

2015 ◽  
Vol 13 (3) ◽  
pp. 389-393 ◽  
Author(s):  
Emine Sert
Keyword(s):  
Catalytic Activity ◽  
Acrylic Acid ◽  
Batch Reactor ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Molar Ratio ◽  
Catalyst Loading ◽  
Toluene Sulfonic Acid ◽  
Effects Of Temperature ◽  
Reaction Media

Abstract Within the framework of green chemistry, catalysts should be met different criteria such as biodegradability, recyclability, flammability, non-toxicity and low price. Acidic deep eutectic solvent (DES) have been synthesized for this purpose, by mixing para-toluene sulfonic acid and choline chloride. The catalytic activity of DES was studied in the esterification of acrylic acid with n-butanol. The usage of DES as catalyst is simple, safe and cheap. The effects of temperature, catalyst loading, n-butanol/acrylic acid molar ratio on the conversion of acrylic acid were performed. The batch reactor experiments were carried out at temperatures of 338, 348, 358 and 368 K, molar ratio of butanol to acrylic acid of 1, 2,3 and catalyst loading of 10, 15, 20 and 90 g/L. 90.2% of acrylic acid conversion was achieved at a temperature of 358 K and catalyst loading of 20 g/L. Reusability of DES was investigated. Reusability and catalytic activity makes DES efficient as catalyst.

A lighter-than-water deep eutectic-solvent-based dispersive liquid-phase microextraction method in a U-shaped homemade device

2018 ◽  
Vol 42 (12) ◽  
pp. 10100-10110 ◽  
Author(s):  
Abolghasem Jouyban ◽  
Mir Ali Farajzadeh ◽  
Mohammad Reza Afshar Mogaddam
Keyword(s):  
Liquid Phase ◽  
Fruit Juice ◽  
Deep Eutectic Solvent ◽  
Liquid Phase Microextraction ◽  
Vegetable Samples ◽  
Glass Filter

A new microextraction method, termed glass-filter-based dispersive liquid-phase microextraction using a lighter-than-water deep eutectic solvent, was developed for the extraction and preconcentration of different classes of pesticides from fruit juice and vegetable samples.

scholarly journals The Anodic Behaviour of Bulk Copper in Ethaline and 1-Butyl-3-Methylimidazolium Chloride

2019 ◽  
Vol 9 (20) ◽  
pp. 4401 ◽  
Author(s):  
Karim ◽  
Aziz ◽  
Brza ◽  
Abdullah ◽  
Kadir
Keyword(s):  
Electrochemical Impedance ◽  
Choline Chloride ◽  
Metallic Copper ◽  
Electrochemical Techniques ◽  
Deep Eutectic Solvent ◽  
Molar Ratio ◽  
Interfacial Region ◽  
Dissolution Mechanism ◽  
Spectroscopic Techniques ◽  
Electrochemical Dissolution

The anodic dissolution of bulk metallic copper was conducted in ionic liquids (ILs)—a deep eutectic solvent (DES) ((CH3)3NC2H4OH) comprised of a 1:2 molar ratio mixture of choline chloride Cl (ChCl), and ethylene glycol (EG)—and imidazolium-based ILs, such as C4mimCl, using electrochemical techniques, such as cyclic voltammetry, anodic linear sweep voltammetry, and chronopotentiometry.To investigate the electrochemical dissolution mechanism, electrochemical impedance spectroscopy (EIS) was used. In addition to spectroscopic techniques, for instance, UV-visible spectroscopy, microscopic techniques, such as atomic force microscopy (AFM), were used. The significant industrial importance of metallic copper has motivated several research groups to deal with such an invaluable metal. It was confirmed that the speciation of dissolved copper from the bulk phase at the interface region is [CuCl3]− and [CuCl4]2− in such chloride-rich media, and the EG determine the structure of the interfacial region in the electrochemical dissolution process. A super-saturated solution was produced at the electrode/solution interface and CuCl2 was deposited on the metal surface.

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