scholarly journals The Risk Assessment of Pesticide Ingestion with Fruit and Vegetables for Consumer’s Health

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Gordana Jurak ◽  
Jasna Bošnir ◽  
Domagoj Đikić ◽  
Ana Mojsović Ćuić ◽  
Iva Pavlinić Prokurica ◽  
...  

Pesticides are chemicals used in agriculture to protect crops from pests. In addition to protection during cultivation, they are also used after harvesting to extend the shelf life of products. Postharvest control stands out, especially when it comes to products imported from distant countries, resulting in increased concentration of pesticides and risk to human health consuming such products. In this study, analyses of pesticide residues were performed on 200 samples of fruits and vegetables. Pesticide residues were identified and quantified in 30 out of 200 samples. Study results revealed imazalil to be the most frequently detected pesticide. Risk assessment was performed on the obtained results, and it was carried out separately for adults and for children under 6 years of age. Imazalil showed the highest ARfD percentage for adults (max% ARfD 251%), and these values were especially high on risk assessment for children, where they amounted up to max% ARfD 1087%. The study of imazalil impact was performed on 16 Swiss albino mice divided into two groups and 4 subgroups. Experimental group animals were treated with the corresponding NOAEL dose of imazalil (10 mg/kg) for 28 days. Body weight was measured before each pesticide application on a digital electronic Sartorius scale. Peripheral blood analysis was performed after 28-day animal exposure to pesticides. Animals were anesthetized, blood samples were obtained by cardiac puncture, and red blood cell (RBC) count, hemoglobin (Hb) concentration, and white blood cell (WBC) count were determined by standard hematological methods. The organs for determination of imazalil concentration were extracted immediately upon animal sacrifice and stored in a freezer at -80°C until analysis. Results show difference in gain weight, and an increase in WBC count was recorded in the experimental group as compared with a control group of animals. The highest imazalil levels were recorded in adipose tissue (45.2‰) which proves tendency to accumulate.

2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Praful Prabhuappa Kapse ◽  
Manisha Kiran

Caring for the persons with first episode psychosis is challenging and demanding. It may lead to the increased burden, expressed emotions among the caregivers. The numerous studies have shown that high burden and negative expressed emotions among caregivers can lead to early relapse in the patients with first episode psychosis. To evaluate the effects of the brief psychoeducation on the caregivers burden and expressed emotions. A quasi experimental - before and after with control group research design was adopted for the study. A total of 60 caregivers have participated in the study, of which 30 caregivers in experimental group and 30 caregivers in the control group. Family Burden Interview Schedule (Pai and Kapoor, 1981) and Attitude Questionnaire (Sethi et al., 1981) was used to assess caregiver's burden and expressed emotions. At end of the psychoeducation intervention, burden among caregivers and negative expressed emotions of the caregivers have significantly reduced. The positive expressed emotions have been increased. Study results demonstrates the importance of psychoeducation intervention in reducing the burden and negative expressed emotions.


2019 ◽  
Vol 88 (3) ◽  
pp. 257-264 ◽  
Author(s):  
Olga Aniołek

This research aimed to evaluate the effect of thyroid hormone deficiency on the erythrocytic system in dogs. Dogs with clinical symptoms of hypothyreosis such as obesity, hyperpigmentation, and lethargy were selected. The dogs demonstrating breed predisposition to hypothyreosis were incorporated in the analysis: Dachshunds, Retrievers, and mixed-breed dogs. A detailed history was taken and clinical, hormonal, biochemical and haematological blood tests were performed. Peripheral blood samples were taken from 53 dogs. Finally, the dogs with the initial T4 (thyroxine) concentration < 1.3 µg/dl and animals demonstrating clinical improvement after a 2-month therapy with levothyroxine at a dose of 10 µg/kg administeredper ostwo times a day were qualified. The animals between 10 months to 13 years of age were divided into two groups: clinically healthy (control group, n = 35) and dogs presenting clinical symptoms of hypothyreosis (experimental group, n = 18). In this research, the broadly described normocytic normochromic non-regenerative anaemia was not diagnosed in dogs with hypothyreosis. However, a positive correlation between T4 and red blood cell indices such as the average mass of haemoglobin per red blood cell, concentration of haemoglobin in a given volume of packed red blood cells as well as a negative correlation with haematocrit value was discovered in the experimental group after the 2-month therapy with levothyroxine. These results point to the influence of thyroid hormones on erythropoiesis. This observation is partially consistent with other studies, which noted the casual link between the changes in red blood cell system and the function of thyroid in dogs and humans.


Author(s):  
JAGADEESWARI J ◽  
KALABARATHI S ◽  
MANGALAGOWRI P

 Objectives: The present aims to assess the level of urinary incontinence in experimental and control group, to assess the effectiveness of vaginal cone therapy on urinary incontinence in experimental group and control group and to associate the post-test level of urinary incontinence with the selected demographic variables among women in the experimental group. Methods: A quantitative quasi-experimental research design was conducted among 60 women with urinary incontinence. Convenience sampling technique was used. Semi-structured interview method was used to collect the demographical data and level of urinary incontinence among women was assessed by urinary incontinence diagnosis questionnaire. Results: Among 60 samples in experimental group 26 women had a moderate level of urinary incontinence, and 4 women had slight urinary incontinence whereas in control group 24 women had moderate level of urinary incontinence and 6 women had slight urinary incontinence. The study results show significant improvement in level of urinary incontinence among experimental group than the control group after the intervention at the level of p<0.05. This reveals that vaginal cone therapy is highly significant in the experimental group because pelvic muscle strength had improved and allows the patient to increase the physiological consciousness and promotes the muscle tone after the use of a vaginal cone. Conclusion: This study proves that vaginal cone therapy is the effective non-pharmacological method, cost-effective method and had no side effects which can be used to treat female urinary incontinence.


Author(s):  
Noelia Muñoz-Fernández ◽  
Javier Ortega-Rivera ◽  
Annalaura Nocentini ◽  
Ersilia Menesini ◽  
Virginia Sánchez-Jiménez

Background: The aim of this study was to assess the efficacy of the school-based “Dat-e Adolescence” prevention program in the reduction of dating aggression and victimization and bullying in adolescents. Method: a RCT design with three waves (pre-test, post-test and follow-up six months apart) and two groups (an experimental group and a control group) were used. One thousand four hundred and twenty three (1423) adolescents, mean age 14.98 (557 in the experimental group) participated in the study. Results: Efficacy evaluation was analyzed using Multiple-group latent growth models and showed that the Dat-e Adolescence program was effective in reducing sexual and severe physical dating violence and bullying victimization. Conclusions: The results suggest that dating violence prevention programs could be an effective approach for tackling different behavioral problems in adolescence given the protective and risk factors shared between dating violence and bullying.


The current study aimed at investigating the effect of KWL and SQ3R strategies on Palestinian eighth graders' reading comprehension skills. To achieve the study goals, the researcher adopted the experimental approach on a sample of (119) female students from Al-Kuwait Secondary School at Rafah governorate for the academic year 2019-2020. The participants were divided into three equivalent groups. The researcher used a pre and post reading comprehension test to achieve the aims of the study. Results revealed there are statistically significant differences at (α ≤ 0.01) in the total average score of the post-test between the first experimental group and the control group in favor of the first experimental group that learns by KWL strategy. Additionally, the study results showed that there are statistically significant differences at (α ≤ 0.01) in the total average score of the post-test between the second experimental group and the control group in favor of the second experimental group that learns by SQ3R strategy. Also, the study results revealed that there are statistically significant differences at (α ≤ 0.01) in the total average score of the post-test between the first and second experimental groups in favor of the first experimental group. In the light of these results, the researcher introduced some recommendations such as designing some training courses for teachers to encourage them to use these strategies.


2021 ◽  
Vol 8 (18) ◽  
pp. 46-56
Author(s):  
Zuzana Hrdličková

It is evident from the PISA 2018 results that a trend in mean performance in reading has been declining in the Slovak Republic. The KEGA Project “Idioms in Business Communication”, run at the Department of English Language, aims at improving reading literacy, widening formal and informal vocabulary and facilitating business communication. Both traditional and modern styles of language teaching are used. The control group of students does a traditional course and the experimental group of students enrols in a “Business Communication” e-course on LMS Moodle platform, as well. With the use of the Internet and supporting materials, this group is involved in various activities. The paper compares the study results of 144 first-year and 97 second-year students of the University of Economics in Bratislava achieved in departmental standardised business English tests after completing three courses in business English for advanced students. The method of Hypothesis Testing (t-Test) assesses the significance of the difference between the levels of knowledge of both groups. The research findings prove that the experimental group of students achieved better results in final evaluation than the control group of students. The results also confirm that an alternative form of business English teaching was effective.


2017 ◽  
Vol 03 ◽  
pp. 11 ◽  
Author(s):  
Damilola A. Omoboyowa ◽  
Agha O. Aja ◽  
Florence Eluu ◽  
Kerian C. Ngobidi ◽  
◽  
...  

The prevalence of parasitic infections such as malaria, which leads to decrease in hematological indices, the major cause of anemia, constitutes a serious health challenge in many developing countries such as Nigeria. This study investigated the effect of methanol seed extract of Aframomum melegueta on selected hematological indices of 2,4-dinitrophenylhydrazine (2,4-DNPH)-induced anemic rats model. The toxicity study and qualitative phytochemical screening of the extract were carried out using standard procedure. Twenty Wistar rats were grouped into five of four rats each (n = 4). Group I: Normal control; Group II: Negative control; Group III: administered 20 ml/kg b.w. of Astifer (Standard drug); Group IV and V were administered 200 and 400 mg/kg b.w. of the extract, respectively. The animals of Groups II to V were induced with 2,4-dinitrophenylhydrazine (20 mg/kg b.w.) once daily for seven consecutive days; their blood samples were collected by ocular puncture into heparinized capillary tubes for hematological analysis and animals with packed cell volume (PCV) ≥ 30% reduction were considered anemic for the study. The result of the qualitative phytochemical analysis showed that the methanol extract tested positive to alkaloids, carbohydrate, saponins, flavonoids, steroids, terpenoids, and anthraquinones. Acute toxicity and lethality studies on methanol extract showed an oral LD50 equal or less than 5000 mg/kg b.w. in mice. The rats administered 20 ml/kg b.w. of Astifer showed significant (P < 0.05) increase in PCV, hemoglobin, red blood cell (RBC) count, white blood cell (WBC) count, and neutrophils count compared with the normal control animals. The rats administered 200 mg/kg b.w. of A. melegueta showed significantly (P < 0.05) higher PCV and WBC count; non significant (P > 0.05) decrease in hemoglobin count, RBC, platelet, neutrophils and lymphocyte count compared with the normal control animals. The rats administered 400 mg/kg b.w. of A. melegueta showed significant (P < 0.05) increase in hemoglobin, platelet, erythrocyte sedimentation rate (ESR) and neutrophils count; non significant (P > 0.05) lower PCV, RBC, WBC count, and lymphocyte count compared with anemic rats administered with 0.3 ml of normal saline. It can be concluded that Aframomum melegueta seed has beneficial immunological and hematological properties in Wistar rats and possessed erythropoietic potentials at minimal dose that support its use for treating anemia.


Author(s):  
Arsalan Majeed Adam ◽  
Muhammad Armughan Ali ◽  
Arshad Ali Shah ◽  
Ather Hasan Rizvi ◽  
Aiman Rehan ◽  
...  

Background: The diagnosis and management of acute coronary syndrome (ACS) have improved significantly over the past few decades; however, the recognition of myocardial ischemia still proves to be a dilemma for cardiologists. The aim of this study was to determine the role of hematological and coagulation parameters in the diagnosis and prognosis of patients with ACS. Methods: This prospective study recruited 250 patients with ACS and 250 healthy controls. The diagnostic role of hematological and coagulation parameters was assessed by comparing the patients with ACS with the control group. The relationships between these parameters and mortality were determined by dividing the patients into 2 groups: Group A (discharged) and Group B (patients who died within 30 days of follow-up). Multivariate Cox regression analysis was performed to calculate the hazard ratio (HR). Results: The mean age of the patients was 55.14±10.71 years, and 65.2% of them were male.  Prothrombin time (P<0.001), activated partial thromboplastin time (P<0.001), mean platelet volume (MPV) (P<0.001), white blood cell (WBC) count (P<0.001), and red blood cell distribution width (RDW) (P<0.001) were significantly higher in the case group than in the control group. WBC count (P<0.001), RDW (P<0.001), and MPV (P<0.001) were significantly higher in the controls than in the case group. The Cox regression model showed that RDW above 16.55% (HR=6.8), MPV greater than 11.25 fL (HR=2.6), and WBC higher than 10.55×103/μL (HR=6.3) were the independent predictors of mortality. Conclusion: In addition to being the independent predictors of short-term mortality, RDW, WBC, and MPV when used together with the coagulation profile may aid in the diagnosis of ACS in patients presenting with chest pain.


2020 ◽  
Vol 7 (1) ◽  
pp. 32-39
Author(s):  
S. Guralska ◽  
T. Kot ◽  
O. Pinskyi ◽  
V. Sokolyuk ◽  
T. Budnik

Aim. To fi nd out the contents and placement of CD4+, CD8+, CD45RA+, CD20+-lymphocyte subpopulations and morphocytochemical architecture of the harderian gland in clinically healthy chickens and for vaccination against infectious bronchitis. Methods. Anatomical, histological, immunohistochemical, optical, morphometric and variational-statistical. Results. The obtained morphometric study results showed that the area of secretory lobules and lymphoid formations was signifi cantly larger in the harderian gland of vaccinated 40-, 90- and 110-day-old chickens. Moreover, the organ size correlates signifi cantly with the development of lymphoid formations, since the area of the secretory lobules in the gland of the experimental group chickens does not differ from that of the control group. Immunohistochemical studies have shown that the number of lymphocytes with CD20+ markers was characterized by a reliable (P < 0.001) increase in B-lymphocytes in the harderian gland of the vaccinated chickens of all ages. Lymphocytes with CD8+ markers were not detected in the gland of vaccinated 8- and 20-day-old chickens. According to cytomorphometric studies, their number in vaccinated 40-, 90- and 110-day-old chickens was signifi cantly (P < 0.001) higher compared to intact birds – 2.11, 2.38 and 2.96 times, respectively. Conclusions. The data on the composition of lymphocytes with CD4+, CD8+, CD45RA+, CD20+ markers in the harderian gland of chickens of different age, on their changes in case of immunization against infectious bronchitis were obtained, and the role of certain clusters at different stages of the immunity formation was determined. The information on the structure, patterns of growth and development of the harderian gland of chickens, which demonstrates the incompleteness of its morphogenesis at the early stages of the postnatal ontogenesis period that should be taken into account during the compilation of vaccine prophylaxis programs, has been supplemented.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 50-55
Author(s):  
Resmy V ◽  
Raj Kumar N

As children grow, they learn each day, of how to live tomorrow watching the grace and disgrace that surround them. The utilization of imaginative strategies to treat mental issues and upgrade emotional well-being is known as art treatment. Art treatment is a strategy established in the possibility that inventive articulation can cultivate recuperating and mental prosperity. Craftsmanship, either making it or survey others' specialty, is utilized to assist individuals with investigating feelings, create mindfulness, adapt to pressure, help confidence, and work on social abilities. Postoperative care may be an emotional and developmental set back to the child. It causes anxiety and pain due to imbalance between environmental and societal demands and child's coping abilities. The present study aims to assess the effectiveness of art therapy on anxiety and pain level among postoperative children. A quantitative true experimental research design was conducted among 30 postoperative children by using a simple random sampling technique and 15 were divided in control and experimental group. The demographic data were collected using structured interview questionnaire. The pre-test was done to assess level of anxiety by five facial anxiety scale and pain by numerical pain scale for both the experimental and control group. The experimental group was given art therapy, the control group was given a routine care and then the post test was done. The study results show that the level of pain and anxiety was considerably reduced in the experimental group than the control group in the post test at p<0.005. This indicates SART therapy is effective non-pharmacological method and cost effective method to treat pain and anxiety among postoperative children. The result of the study is it was concluded that art therapy as no side effects and it is an easy and comfortable method which can be practiced to treat pain and anxiety.


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