scholarly journals Long-Term Outcomes of Thermal Ablation for Benign Thyroid Nodules: The Issue of Regrowth

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Jung Suk Sim ◽  
Jung Hwan Baek
Keyword(s):  
Treatment Effect ◽  
Thermal Ablation ◽  
Thyroid Nodules ◽  
Long Term Outcomes ◽  
Safe Alternative ◽  
Factors Affecting ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid ◽  
Symptom Recurrence

Thermal ablation (TA) for benign thyroid nodules (BTNs) is widely accepted as an effective and safe alternative to surgery. However, studies on the long-term outcomes of TA have reported problems with nodule regrowth and symptom recurrence, which have raised the need for adequate control of regrowth. Therefore, a more complete TA with a longer-lasting treatment effect may be required. In this study, we review and discuss long-term outcomes and regrowth of BTNs following TA and evaluate factors affecting the long-term outcomes. We also discuss the management of regrowth based on long-term outcomes.

scholarly journals Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 35 (2) ◽  
pp. 339-350 ◽  
Author(s):  
Se Jin Cho ◽  
Jung Hwan Baek ◽  
Sae Rom Chung ◽  
Young Jun Choi ◽  
Jeong Hyun Lee
Keyword(s):  
Systematic Review ◽  
Thermal Ablation ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
Long Term Results ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Effect of thermal ablation on HSP70 expression in benign thyroid nodules

2014 ◽  
Vol 35 (11) ◽  
pp. 1215
Author(s):  
Lei YAN ◽  
Jian-quan ZHANG ◽  
Qian PAN ◽  
Jian-ming ZHENG ◽  
Yan-hong Lv
Keyword(s):  
Thermal Ablation ◽  
Thyroid Nodules ◽  
Hsp70 Expression ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Improving the Long-term Management of Benign Thyroid Nodules

JAMA ◽  
2015 ◽  
Vol 313 (9) ◽  
pp. 903 ◽  
Author(s):  
Anne R. Cappola ◽  
Susan J. Mandel
Keyword(s):  
Thyroid Nodules ◽  
Term Management ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

scholarly journals Long-Term Results of Ultrasound-Guided Radiofrequency Ablation of Benign Thyroid Nodules: State of the Art and Future Perspectives—A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Hervé Monpeyssen ◽  
Ahmad Alamri ◽  
Adrien Ben Hamou
Keyword(s):  
Systematic Review ◽  
Radiofrequency Ablation ◽  
Thyroid Nodules ◽  
Long Term Results ◽  
Future Perspectives ◽  
Time Duration ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

BackgroundNearly 20 years after the first feasibility study, minimally invasive ultrasound (US)-guided therapeutic techniques are now considered as a safe and effective alternative to surgery for symptomatic benign thyroid nodules. Radiofrequency ablation (RFA) is one of the most widely used treatment in specialized thyroid centers but, due to the relatively recent introduction into clinical practice, there are limited long-term follow-up studies. Aim of our work was to review the outcomes of RFA on solid nonfunctioning and on autonomous thyroid nodules (AFTN) on a long-time period for assessing the results in term of efficacy, complications, and costs and to compare them to the current indications of RFA.MethodsA systematic review was performed using EMBASE and Medline library data between 2008 and 2021. Seventeen studies evaluated RFA for the treatment of benign solid (nonfunctioning or autonomous) thyroid nodules, with an at least 18 months of follow-up. Data extraction and quality assessment were performed by two endocrinologist according to PRISMA guidelines. Anthropometric data, safety and efficacy parameters were collected.ResultsThe majority of the studies was retrospective study and reported 933 nodules, mostly solid. Baseline volume ranged between 6.1 ± 9.6 and 36.3 ± 59.8 ml. Local analgesia was used and the time duration of the treatment was between 5 ± 2 and 22.1 ± 10.9 min. The volume reduction rate at 12 months ranged from 67% to 75% for the nodule treated with a single procedure and reached to 93.6 ± 9.7% for nodules treated with repeat ablations. The regrowth rate at 12 months ranged from 0% to 34%.ConclusionAll the studies under examination consistently validated the long-term clinical efficacy and the substantial safety of RFA for the treatment of benign thyroid nodules. Thermal ablation, however, is an operator-dependent technique and should be performed in centers with specific expertise. The selection of the patients should be rigorous because the nodule size and the structural and functional characteristics influence the appropriateness and the outcomes of the treatment. Future perspectives as the treatment of micro-papillary thyroid cancer or cervical recurrence need further investigations.

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