scholarly journals Association between TSH Values and GFR Levels in Euthyroid Cases with Metabolic Syndrome

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
H. Keskin ◽  
K. Cadirci ◽  
K. Gungor ◽  
T. Karaaslan ◽  
T. Usta ◽  
...  

Background. Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney disease. Although the negative effects of high thyroid-stimulating hormone (TSH) values on glomerular filtration rate (GFR) levels have been known for years, the negative effects of increased TSH on GFR in euthyroid cases have been reported in recent years. This study was aimed at investigating the association between the effect of increased TSH values and estimated-GFR (eGFR) levels in euthyroid cases with MetS. Methods. For this hospital-based descriptive study, 191 MetS cases (123 females, 68 males) were evaluated. Those whose TSH was not within 0.5–4.5 uIU/mL, eGFR was <40 mL/min/1.73 m2, and/or reported any thyroid/kidney disease were excluded. Partial correlation coefficients were calculated to investigate the relationship between the eGFR values and several other numerical variables while controlling for age and BMI in addition to the adjusted gender effect. Thereafter, the multiple linear regression analysis with a stepwise variable selection approach was used to reveal the independent factors that could affect the logarithmically transformed eGFR. Results. The median age was 52 (19–65) years, the median eGFR was 94.3 (41.3–194) mL/min/1.73 m2, and the median TSH was 1.58 (0.50–4.50) uIU/mL in the whole group. Increased TSH even in the normal range was associated with eGFR after adjusting for age and body mass index (BMI), especially in females. The high age (b = −0.160, p = 0.005 ), high BMI (b = −0.134, p = 0.020 ), high TSH (b = −0.380, p < 0.01 ), and high uric acid (b = −0.348, p < 0.01 ) were found as significant predictors of the eGFR in MetS patients. Conclusion. Independent of age and BMI, elevated TSH even in the euthyroid range showed an association with the eGFR in female MetS cases who had normal kidney functions. This correlation was stronger than the correlations between the eGFR and the MetS diagnostic parameters. These findings need further studies on the issue..

2019 ◽  
Vol 8 (1) ◽  
pp. 82
Author(s):  
Roxana Dragomir ◽  
Mircea Hogea ◽  
Marius Moga ◽  
Dana Festila ◽  
Calin Cobelschi

Background: The spleen plays a central role in a range of diseases. As such, great emphasis has been placed on the procedure of spleen removal, the benefits and the numerous associated complications. Given the immediate risk of the thrombotic complications, the aim of this study was to evaluate clinical and laboratory patient characteristics in non-traumatic diseases of the spleen, and to investigate possible predictive factors for platelet count variation following the procedure. Methods: A total of 72 patients who underwent splenectomy were included in this retrospective study. Correlation coefficients as well as multiple linear regressions were used to assess the relationship between post-splenectomy platelet count and various preoperative clinical and laboratory patient characteristics. Results: Following multiple linear regression analysis, we determined that 54.93% of post-splenectomy platelet count variation was explained by admission platelet count (p = 0.00), lymphocyte count (p = 0.04), WBC count (p = 0.00), LOS (p = 0.00), patient gender (p = 0.00), spleen accessibility on admission (p = 0.02) and PT (p = 0.00). Conclusions: Platelet count variation following splenectomy for non-traumatic diseases can be predicted by assessing preoperative patient characteristics. The implications of this study suggest that by means of a prediction model, patient care could benefit from assessing and addressing various preoperative factors that lead to these complications.


2012 ◽  
Vol 38 (2) ◽  
pp. 116-126 ◽  
Author(s):  
V. Finsen ◽  
O. Rod ◽  
K. Rød ◽  
B. Rajabi ◽  
P. S. Alm-Paulsen ◽  
...  

We reviewed 260 patients who had been treated non-operatively for a dorsally displaced distal radius fracture a mean 6.3 (range 2.5–12.7) years earlier, in an attempt to find the limits of displacement compatible with a good clinical outcome. We excluded patients with previous or later injuries to the same limb. Bivariate analysis revealed a highly statistically significant relationship between radiographic displacement at review and clinical outcome scores. Correlation coefficients varied between 0.14 and 0.30. However, multiple linear regression analysis using most factors commonly thought to be of importance in determining the clinical outcome as independent variables explained only 23% of the variability of the clinical outcome. Dorsal angulation, ulnar variance, and radial inclination together accounted for only 11% of the variability. We conclude that the final alignment of the distal radius as shown radiologically has only a minor influence on the clinical outcome of Colles’ type distal radius fractures.


Author(s):  
Brian D. Lowe

Psychophysical approaches to quantifying perceived effort have been used to evaluate the physical demand of many industrial work activities. An experiment was conducted to examine the relationship between ratings of whole-body perceived exertion and differentiated, regional ratings of exertion. The Borg, CR-10 scale was used by 16 subjects performing a simulated repetitive lifting task. Ratings of perceived exertion were obtained for the arms, legs, torso, and central (cardiorespiratory) effort sensations as well as a rating of overall, whole-body exertion. A multiple linear regression analysis was used to predict the whole-body rating of exertion from the differentiated ratings in lifting tasks using both a squat and stoop posture. In the stoop posture condition the coefficient of determination between whole-body perceived exertion and the model including arm, torso, and central ratings was R2=0.81. In the squat posture condition, the final regression model predicting whole-body exertion contained only the rating from the legs (R2 = 0.62). Differentiated ratings explained the majority of the variance in whole-body perceived exertion for squat and stoop lifting tasks.


2021 ◽  
Vol 12 ◽  
Author(s):  
Shuguang Zhao ◽  
Yiming Liu

This study examines the relationship between cognitive and affective factors and people's information-seeking and -avoiding behaviours in acute risks with a 1,946-sample online survey conducted in February 2020, during the outbreak of the COVID-19 pandemic in mainland China. Multiple linear regression analysis showed that perceived information insufficiency correlates negatively with information-seeking behaviour and there was an inverted U-shaped relationship between information insufficiency and avoidance behaviour. As for the risk-related cognitive factors, information seeking increases as perceived severity of risks rises, while information avoiding increases as perceived susceptibility rises. Perceived response efficacy positively correlates with information-seeking and negatively with information-avoidance behaviours. Preliminary results also indicated that different affective factors relate to information-seeking and avoidance behaviours differently.


2020 ◽  
Author(s):  
Gesang Sudrajad ◽  
J.E Sutanto

The purpose of this study was to examine the effect of simultaneous and partial marketing mix on the purchase decision of prospective consumers of Grand Cempaka Housing.This research uses quantitative methods, and is a survey research from the types of explanatory research whose focus is placed on relational research: studying the relationship of variables. The object of research is the residents of Pasuruan City and the sample in this study is the Prospective Consumer of Grand Cempaka Housing. Data analysis uses multiple linear regression analysis methods.The results of the analysis show that Products, Prices, Places and Promotions simultaneously have a significant effect on the Decision of Purchasing Prospective Consumers of Grand Cempaka Housing. This shows that the marketing mix is one of the marketing strategies that should be considered so that the implementation of the marketing strategy can run successfully because the elements in the marketing mix influence each other. Variables in the marketing mix which include Products, Prices, Places and Promotions partially have a significant effect on the Decision of Purchasing Prospective Consumers of Grand Cempaka Housing. Keywords: marketing mix; purchase decision; property; housing


Author(s):  
Nalan Aksakal

The aim of this study is to determine School of Physical Education and Sports students’ attitudes background about edutainment approach. A total of 338 students participated in the study; 118 female and 220 male. The study used Attitude Towards Edutainment Scale for data collection purposes. The data obtained were analyzed through descriptive statistics, Explanatory Factor Analysis, Correlation Analysis and Multiple Linear Regression Analysis by using SPSS 18 software. According to the findings the relationship among attitude factors regarding edutainment, correlations among factors range between ,51 and ,63. The lowest correlation value (0.51) was calculated for “perceived learning effect” and “drama” and “practice” factor while the highest correlation (0.63) for “expression and material and drama and practice” factors. Pearson correlation coefficients imply a medium level correlation among all factors. According to standardized beta (β) values in regression model, which shows the correlation among variables, “perceived learning effect” factor has the strongest effect on all recommendation and satisfaction-which are the dependent variables. In conclusion, the study found a meaningful relationship between edutainment approach and “recommendation” and edutainment approach and “satisfaction” It was also found that “satisfaction” has a strong effect on recommendation variable.


2019 ◽  
Vol 1 (2) ◽  
pp. 382-393
Author(s):  
Rizki Akbari ◽  
Kokom Komariah ◽  
Dicky Jhoansyah

The purpose of this study was to determine the impact of employee relations (variable X1) and Work Discipline (variable X2) on Employee Performance (variable Y). The method used in this research is to use descriptive and associative methods. Data collection techniques used by researchers in this study are through observation, questionnaire interviews, documentation and literature studies. The data analysis technique used is the validity test, reliability test, multiple linear regression analysis, including the test of the coefficient of determination and multiple correlation coefficients. The results of the test of the coefficient of determination seen from the value (Adjusted R2) of 0.531 can be interpreted that the impact of employee relations and working discipline on employee performance is equal to 53.1%. The remaining 46.9% is influenced by other factors outside this study. Conclusion, there is a moderate relationship between employee relations and work discipline with employee performance. Keywords: Employee Relations, Work Discipline, Employee Performance


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Deepak Gowda Sadashivappa Pateel ◽  
Shilpa Gunjal ◽  
Liew Fong Fong ◽  
Nur Sulwana Mohd Hanapi

Background. Saliva, as a complex biofluid, plays a pivotal role in maintaining oral health and tooth integrity. There has been inconsistent data available on the relationship between salivary parameters and oral health. This study aims to investigate the association between salivary statherin, acidic proline-rich proteins (aPRP), and calcium with oral hygiene status. Methods. One hundred and eighty-eight healthy subjects aged between 18 and 50 years with varying oral hygiene status who gave consent to participate were included in this cross-sectional study. The subjects were recruited from primary oral health care of MAHSA University. Oral hygiene of all the participants was measured using Oral Hygiene Index–Simplified (OHI-S). Stimulated saliva collected using paraffin wax was analyzed for salivary statherin, aPRP, and calcium. The relationship between salivary statherin, aPRP, and calcium levels with OHI-S was assessed using Spearman’s Rank correlation coefficient; the strength of relationship was assessed by multiple linear regression analysis. Results. The study found a weak positive correlation (r = 0.179, p  = 0.014) between salivary statherin and OHI-S; weak negative correlation (r = −0.187, p  = 0.010) between salivary aPRP and OHI-S; and moderate negative correlation between salivary statherin and salivary aPRP levels (r = −0.50, p  < 0.001) which were statistically significant. Conclusion. Poor oral hygiene is associated with increased statherin and reduced aPRP levels in saliva. Thus, these salivary components may have a role in predicting oral hygiene status.


2020 ◽  
Vol 18 (3) ◽  
pp. 459-465
Author(s):  
Dipak Kunwar ◽  
Rajyashree Kunwar ◽  
Barsha Shrestha ◽  
Richa Amatya ◽  
Ajay Risal

Background: Depression and other mental illness are very common among chronic kidney disease and also Quality of life has been found significantly impaired in chronic kidney disease. The objective of our study is to study Depression, Quality of life and its associations in chronic kidney disease. Methods: This was a descriptive cross-sectional study. We used convenient method of sampling for data collection. The World Health Organization Quality-of-Life 8-question scale was used for estimating quality of life and Beck Depression Inventory  was used for the assessment of depression.  Independent samples t-test was conducted to analysed bivariate relationship of sociodemographic factors with depression and Quality of life scores and multiple linear regression analysis was performed to determine predictors of Quality of life. Results: The 75.5% participants found to have depression. Depression was found statistically significant across socioeconomic status (p value 0.04) and other medical comorbidities (p value 0.04). Variables found to be significantly associated with total quality of life in multiple linear regression analysis were caste (p value 0.03), socioeconomic status (p value 0.009) and depression (p value 0.001). Conclusions: Depression and reduced quality of life is very common among chronic kidney patients. Low socioeconomic status and comorbid medical conditions were associated with depression and caste, low socioeconomic status and depression were associated with low quality of life. Screening and management of depression should be included in the routine care and it could help improving the quality of life of patients with chronic kidney disease. Keywords: chronic kidney disease; depression; quality of life


2019 ◽  
Author(s):  
Esther Iriagbonse Eroje ◽  
Erasmus Kofi Appiah ◽  
Alezi Braimoh Ifindon Eroje ◽  
MEER ZAKIRULLA ◽  
Jimly James Kunjappu ◽  
...  

Abstract Background Leadership has become the key issues in managing the organization, the emerging business and economic environments have forced organizations to be flexible, adaptive, entrepreneurial and innovative to meet changing demand of the present-day business environment. The purpose of the present study is to examine the relationship between the various dimensions of transformational leadership (predictor variable) and their effects on employees’ job satisfaction (criterion variable) in three selected Colleges (Medicine, Dentistry and Science) in King Khalid University. Methods The methodology employed in this study was a quantitative and cross-sectional correlational survey type of design Data collection was done using a questionnaire design that was directly administered to the participants. 250 questionnaires were sent to the participating three colleges (Medicine, Dentistry and Sciences). Results The findings of the multiple linear regression analysis indicated a weak positive association between transformational leadership behaviour and employees’ job satisfaction (R-value 0.386). The multiple linear regression analysis signifies a weak positive correlation between transformational leadership behaviour and job satisfaction (R-value 0.386). A p-value in Spearman’s rho that is less than the 0.05 level of significance indicated that there is a significant level of relationship which exists between transformational leadership behaviour and job satisfaction. Conclusions This study concluded that transformational leadership behaviour and its four dimensions showed a weak positive correlation with a statistically significant level of relationship between transformational leadership behaviour and employees’ job satisfaction among three selected colleges (Medicine, Dentistry and Sciences) in King Khalid University, Abha, Saudi Arabia.


Sign in / Sign up

Export Citation Format

Share Document