scholarly journals Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Yaping Chang ◽  
Meng Zhu ◽  
Christopher Vannabouathong ◽  
Raman Mundi ◽  
Roland S. Chou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Medical Cannabis ◽  
Chronic Noncancer Pain ◽  
Line Therapy ◽  
Cochrane Database ◽  
Immunodeficiency Virus ◽  
Number Of Publications ◽  
Noncancer Pain ◽  
Guidelines And Recommendations

Purpose. Medical cannabis for patients with chronic noncancer pain (CNCP) has been the focus of numerous health care recommendations. We conducted a systematic review to identify and summarize the currently available evidence-based recommendations. Methods. We searched MEDLINE, EMBASE, PsycINFO, the Cochrane database of systematic reviews, and websites for clinical guidelines and recommendations. We summarized the type of the publications, developers, approach of health care recommendation development, year and country of publication, and conditions that were addressed. We categorized the direction and strength of each recommendation. Results. We identified 12 eligible publications. Publication years ranged from 2007 to 2019; four (33.3%) of them were published in 2018. Canada ranked first for the number of publications (n = 4, 33.3%). Most (n = 11, 92%) of the included recommendations were based on both a systematic review of the best evidence and expert consensus. All the included publications provided a recommendation supporting medical cannabis for CNCP in general and for the specific conditions of neuropathic pain, chronic pain in people living with Human Immunodeficiency Virus (HIV), and chronic abdominal pain, with detailed information sharing and comprehensive consideration of a patient’s own values and preferences. Conclusion. Clinicians can attend to the guidance currently offered, being aware that only weak recommendations are available for medical cannabis in patients with CNCP, as a third- or fourth-line therapy. Detailed discussions with patients regarding the benefits in reducing pain and potential adverse effects are required before its prescription.

scholarly journals A Mapping Literature Review of Medical Cannabis Clinical Outcomes and Quality of Evidence in Approved Conditions in the USA from 2016 to 2019

2021 ◽  
pp. 1-22
Author(s):  
Sebastian Jugl ◽  
Aimalohi Okpeku ◽  
Brianna Costales ◽  
Earl J. Morris ◽  
Golnoosh Alipour-Haris ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
The Body ◽  
Medical Cannabis ◽  
High Quality ◽  
Chronic Noncancer Pain ◽  
High Quality Evidence ◽  
Improved Outcomes ◽  
Noncancer Pain ◽  
Study Setting

In 2017, a National Academies of Sciences, Engineering, and Medicine (NASEM) report comprehensively evaluated the body of evidence regarding cannabis health effects through the year 2016. The objectives of this study are to identify and map the most recently (2016–2019) published literature across approved conditions for medical cannabis and to evaluate the quality of identified recent systematic reviews, published following the NASEM report. Following the literature search from 5 databases and consultation with experts, 11 conditions were identified for evidence compilation and evaluation: amyotrophic lateral sclerosis, autism, cancer, chronic noncancer pain, Crohn’s disease, epilepsy, glaucoma, human immunodeficiency virus/AIDS, multiple sclerosis (MS), Parkinson’s disease, and posttraumatic stress disorder. A total of 198 studies were included after screening for condition-specific relevance and after imposing the following exclusion criteria: preclinical focus, non-English language, abstracts only, editorials/commentary, case studies/series, and non-U.S. study setting. Data extracted from studies included: study design type, outcome definition, intervention definition, sample size, study setting, and reported effect size. Few completed randomized controlled trials (RCTs) were identified. Studies classified as systematic reviews were graded using the Assessing the Methodological Quality of Systematic Reviews-2 tool to evaluate the quality of evidence. Few high-quality systematic reviews were available for most conditions, with the exceptions of MS (9 of 9 graded moderate/high quality; evidence for 2/9 indicating cannabis improved outcomes; evidence for 7/9 indicating cannabis inconclusive), epilepsy (3 of 4 graded moderate/high quality; 3 indicating cannabis improved outcomes; 1 indicating cannabis inconclusive), and chronic noncancer pain (12 of 13 graded moderate/high quality; evidence for 7/13 indicating cannabis improved outcomes; evidence from 6/7 indicating cannabis inconclusive). Among RCTs, we identified few studies of substantial rigor and quality to contribute to the evidence base. However, there are some conditions for which significant evidence suggests that select dosage forms and routes of administration likely have favorable risk-benefit ratios (i.e., epilepsy and chronic noncancer pain). The body of evidence for medical cannabis requires more rigorous evaluation before consideration as a treatment option for many conditions, and evidence necessary to inform policy and treatment guidelines is currently insufficient for many conditions.

Are Physicians Safely Prescribing Opioids for Chronic Noncancer Pain? A Systematic Review of Current Evidence

Pain Practice ◽  
2015 ◽  
Vol 16 (3) ◽  
pp. 370-383 ◽  
Author(s):  
Juliana Tournebize ◽  
Valérie Gibaja ◽  
Amandine Muszczak ◽  
Jean-Pierre Kahn
Keyword(s):  
Systematic Review ◽  
Current Evidence ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals Outcomes Associated with Opioid Use in the Treatment of Chronic Noncancer Pain in Older Adults: A Systematic Review and Meta-Analysis

2010 ◽  
Vol 58 (7) ◽  
pp. 1353-1369 ◽  
Author(s):  
Maria Papaleontiou ◽  
Charles R. Henderson Jr ◽  
Barbara J. Turner ◽  
Alison A. Moore ◽  
Yelena Olkhovskaya ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Meta Analysis ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

Factors that Influence Coping with Chronic Noncancer Pain in European Countries: A Systematic Review of Measuring Instruments

2020 ◽  
Vol 21 (2) ◽  
pp. 123-133 ◽  
Author(s):  
Rocío Cáceres-Matos ◽  
Eugenia Gil-García ◽  
Andrés Cabrera-León ◽  
Ana María Porcel-Gálvez ◽  
Sergio Barrientos-Trigo
Keyword(s):  
Systematic Review ◽  
European Countries ◽  
Measuring Instruments ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals A Systematic Review and Jurisdictional Scan of the Evidence Characterizing and Evaluating Assisted Peritoneal Dialysis Models

2020 ◽  
Vol 15 (4) ◽  
pp. 511-520 ◽  
Author(s):  
Mark Hofmeister ◽  
Scott Klarenbach ◽  
Lesley Soril ◽  
Nairne Scott-Douglas ◽  
Fiona Clement
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Peritoneal Dialysis ◽  
Cochrane Central Register ◽  
Home Based ◽  
Cochrane Database ◽  
Central Register ◽  
Professional Assistance ◽  
Dialysis Outcomes ◽  
Assisted Peritoneal Dialysis

Background and objectivesCompared with hemodialysis, home peritoneal dialysis alleviates the burden of travel, facilitates independence, and is less costly. Physical, cognitive, or psychosocial factors may preclude peritoneal dialysis in otherwise eligible patients. Assisted peritoneal dialysis, where trained personnel assist with home peritoneal dialysis, may be an option, but the optimal model is unknown. The objective of this work is to characterize existing assisted peritoneal dialysis models and synthesize clinical outcomes.Design, setting, participants, & measurementsA systematic review of MEDLINE, Cochrane Central Register of Controlled Trails, Cochrane Database of Systematic Reviews, Embase, PsycINFO, and CINAHL was conducted (search dates: January 1995–September 2018). A focused gray literature search was also completed, limited to developed nations. Included studies focused on home-based assisted peritoneal dialysis; studies with the assist provided exclusively by unpaid family caregivers were excluded. All outcomes were narratively synthesized; quantitative outcomes were graphically depicted.ResultsWe included 34 studies, totaling 46,597 patients, with assisted peritoneal dialysis programs identified in 20 jurisdictions. Two categories emerged for models of assisted peritoneal dialysis on the basis of type of assistance: health care and non–health care professional assistance. Reported outcomes were heterogeneous, ranging from patient-level outcomes of survival, to resource use and transfer to hemodialysis; however, the comparative effect of assisted peritoneal dialysis was unclear. In two qualitative studies examining the patient experience, the maintenance of independence was identified as an important theme.ConclusionsReported outcomes and quality were heterogeneous, and relative efficacy of assisted peritoneal dialysis could not be determined from included studies. Although the patient voice was under-represented, suggestions to improve assisted peritoneal dialysis included using a person-centered model of care, ensuring continuity of nurses providing the peritoneal dialysis assist, and measures to support patient independence. Although attractive elements of assisted peritoneal dialysis are identified, further evidence is needed to connect assisted peritoneal dialysis outcomes with programmatic features and their associated funding models.

scholarly journals Utilization of Health Care Services and Ambulatory Resources Associated with Chronic Noncancer Pain

Pain Medicine ◽  
2017 ◽  
Vol 18 (7) ◽  
pp. 1236-1246 ◽  
Author(s):  
Cynthia Kay ◽  
Erica Wozniak ◽  
Joanne Bernstein
Keyword(s):  
Health Care ◽  
Health Care Services ◽  
Chronic Noncancer Pain ◽  
Care Services ◽  
Noncancer Pain

scholarly journals Health care resource use and cost differences by opioid therapy type among chronic noncancer pain patients

2017 ◽  
Vol Volume 10 ◽  
pp. 1713-1722 ◽  
Author(s):  
Pamela Landsman-Blumberg ◽  
Nathaniel Katz ◽  
Kavita Gajria ◽  
Anna D’Souza ◽  
Sham L Chaudhari ◽  
...  
Keyword(s):  
Health Care ◽  
Resource Use ◽  
Opioid Therapy ◽  
Health Care Resource ◽  
Chronic Noncancer Pain ◽  
Health Care Resource Use ◽  
Noncancer Pain ◽  
Pain Patients ◽  
Cost Differences

Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review

2003 ◽  
Vol 4 (5) ◽  
pp. 231-256 ◽  
Author(s):  
Ewan McNicol ◽  
Nathalie Horowicz-Mehler ◽  
Ruth A Fisk ◽  
Kyle Bennett ◽  
Maria Gialeli-Goudas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain
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