scholarly journals Zinner Syndrome with Ectopic Ureter Emptying into Seminal Vesicle

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
M. Hevia Palacios ◽  
M. Álvarez-Maestro ◽  
J. Gómez Rivas ◽  
A. Aguilera Bazan ◽  
L. Martínez-Piñeiro
Keyword(s):  
Seminal Vesicle ◽  
Renal Agenesis ◽  
Left Kidney ◽  
Ejaculatory Duct ◽  
Ectopic Ureter ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive ◽  
Ejaculatory Duct Obstruction ◽  
Multiple Cysts

A 66-year-old male patient in follow-up in the urology department for a non-muscle-invasive bladder cancer was detected by ultrasound to have absence of the left kidney and a cystic, multilobed image at the location of the seminal vesicle. Magnetic resonance imaging reveals left renal agenesis and the existence of multiple cysts in the ipsilateral seminal vesicle that reaches a size of 6.9 × 3.7   cm , as well as a ureteral remnant that opens into the seminal vesicle. The patient does not present urinary symptoms, neither pain with ejaculation nor hematuria. A triad of seminal vesicle cyst, ipsilateral renal agenesis, and ipsilateral ejaculatory duct obstruction is known as Zinner syndrome. Congenital anomalies of the seminal vesicles are rare; some of them are associated with malformations of the upper urinary system. Seminal vesicle cysts are associated with ipsilateral renal agenesis and ectopic or dysplastic ureter. Patients may remain asymptomatic and be diagnosed incidentally or may present with symptoms such as increased urinary frequency, dysuria, recurrent infections, pain with ejaculation, and perineal discomfort.

Zinner Syndrome with Ectopic Ureter Remnant

2021 ◽  
Vol 17 ◽  
Author(s):  
Ara Ko ◽  
Sung Bin Park ◽  
Hyun Jeong Park ◽  
Eun Sun Lee
Keyword(s):  
Seminal Vesicle ◽  
Ejaculatory Duct ◽  
Outlet Obstruction ◽  
Ectopic Ureter ◽  
Cystic Dilatation ◽  
Unilateral Renal Agenesis ◽  
Rare Congenital Abnormality ◽  
Mesonephric Duct ◽  
Clinical Triad ◽  
Ejaculatory Duct Obstruction

: Zinner syndrome is a rare congenital abnormality defined by a clinical triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. Most patients are asymptomatic, but if the cystic dilatation of the seminal vesicle becomes significant, it can result in urinary symptoms such as dysuria and urinary retention. This rare developmental anomaly related to the mesonephric duct can also present with other abnormalities. Here, we report our experience of Zinner syndrome with bladder outlet obstruction and an ectopic ureter remnant.

scholarly journals Zinner Syndrome

2021 ◽  
Author(s):  
Abakar Djidda ◽  
Fatima-Ezzahrae Badi ◽  
Mouna Sabiri ◽  
Samia Elmanjra ◽  
Samira Lezar ◽  
...  
Keyword(s):  
Young Patient ◽  
Seminal Vesicle ◽  
Renal Agenesis ◽  
Ejaculatory Duct ◽  
Developmental Anomaly ◽  
Unilateral Renal Agenesis ◽  
Duct Obstruction ◽  
Seminal Vesicle Cyst ◽  
Mesonephric Duct ◽  
Ejaculatory Duct Obstruction

Zinner syndrome is a developmental anomaly of the urogenital tract. This condition is defined by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst and ipsilateral ejaculatory duct obstruction. The syndrome is due to malformation of the mesonephric duct during embryogenesis. The condition used to be rare but is now frequently encountered due to the advent of MRI and CT. MRI confirms the diagnosis by revealing the seminal vesicle cyst and its contents, and the ejaculatory duct obstruction, while CT confirms renal agenesis. We report the case of a young patient with Zinner syndrome.

scholarly journals Rare Cause of Painful Ejaculation – Zinner’s Syndrome: A Case Report

2020 ◽  
Vol 3 ◽  
pp. 1
Author(s):  
Devimeenal Jaganathan ◽  
Gopinathan Kathirvelu ◽  
Suriyaprakash Nagarajan ◽  
Usha Nandhini Ganesan
Keyword(s):  
Seminal Vesicle ◽  
Renal Agenesis ◽  
Ejaculatory Duct ◽  
Resonance Imaging ◽  
Unilateral Renal Agenesis ◽  
Common Complaint ◽  
Radiologic Imaging ◽  
Rare Congenital Abnormality ◽  
Ejaculatory Duct Obstruction ◽  
Zinner’S Syndrome

Zinner’s syndrome is a rare congenital abnormality consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The mutual embryological origins of the seminal vesicle and the ureteral bud from the Wolffian duct result in both anomalous seminal vesicle and urinary tracts. Most cases have nonspecific symptoms such as prostatism, urinary urgency, dysuria, painful ejaculation, and perineal discomfort. The usual presentation is between the third and fourth decades of life, with infertility being the most common complaint. Ultrasound and magnetic resonance imaging can easily detect this condition. We present here an extremely rare developmental anomaly involving the Wolffian ducts, which would remain undiagnosed but for radiologic imaging.

A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical prophylaxis

2021 ◽  
pp. 039156032110222
Author(s):  
Vincenzo Serretta ◽  
Ettore De Berardinis ◽  
Alchiede Simonato ◽  
Alessio Guarneri ◽  
Nino Dispensa ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Oral Administration ◽  
Ellagic Acid ◽  
Invasive Bladder Cancer ◽  
Prophylactic Effect ◽  
Annona Muricata ◽  
Muscle Invasive Bladder Cancer ◽  
Number Of Patients ◽  
Muscle Invasive

Introduction: BCG and MMC shortage and Covid-19 pandemic, more recently, limit accessibility to maintenance regimen in intravesical prophylaxis against recurrence of non-muscle invasive bladder cancer (NMIBC). Ellagic acid (EA) and Annona muricata (AM) exert antitumor activity against different human tumours. An observational prospective study on the prophylactic effect of oral administration of EA+AM in patients avoiding maintenance regimen is presented. Materials and methods: Patients affected by NMIBC and not undergoing maintenance after a 6-week course of intravesical prophylaxis with MMC or BCG were entered. Tis and very high-risk tumours were excluded. After informed consent, the patients were subdivided in relation to the oral assumption or not of EA (100 mg) plus AM (100 mg), daily for 6 months. All patients were submitted to 3-month cytology and cystoscopy. Results: 162 (90%) of 180 entered patients are evaluable, 90 and 72 receiving or not EA+AM. No difference emerged in patients’ characteristics between the two groups. BCG was given in 86 (54%) and chemotherapy in 74 (46%) patients. The recurrence free rate at 3, 6 and 12 months in patients assuming or not EA was 96.5% versus 84.6% ( p = 0.003), 85.4% versus 64.8% ( p = 0.005) and 74.2% versus 60.6% ( p = 0.246), respectively. The recurrence free survival at 12 months in patients assuming or not EA was 63.0% versus 34.5% ( p < 0.0001). Discussion and conclusions: Our study suffers several limits: not randomized trial although prospective, limited number of patients and short follow-up, nevertheless it shows the prophylactic effect of oral EA+AM in absence of maintenance after intravesical chemotherapy or immunotherapy induction.

A wide spectrum of rare clinical variants of Zinner syndrome

2021 ◽  
Vol 14 (1) ◽  
pp. e239254
Author(s):  
Harkirat Singh Talwar ◽  
Ankur Mittal ◽  
Tushar Aditya Narain ◽  
Vikas Kumar Panwar
Keyword(s):  
Congenital Malformations ◽  
Renal Agenesis ◽  
Wide Spectrum ◽  
Ejaculatory Duct ◽  
Seminal Vesicles ◽  
Duct Obstruction ◽  
Cyst Excision ◽  
Maintenance Haemodialysis ◽  
Clinical Variants ◽  
Ejaculatory Duct Obstruction

Congenital malformations of the seminal vesicles (SVs) are rare and are associated with abnormalities of the ipsilateral urinary tracts as embryologically both the ureteral buds and SVs arise from the mesonephric ducts. The triad of SV cysts, ipsilateral renal agenesis and ejaculatory duct obstruction is known as the Zinner syndrome. We, herein, present three very rare presentations of Zinner syndrome. Case 1 presented with haematuria, and was found to have a large SV cyst with stones and underwent a robotic cyst excision. Case 2 presented with primary infertility, and was found to have a variant of Zinner syndrome. Case 3 was a known case of chronic kidney disease on maintenance haemodialysis who presented with fever and oliguria. He was found to have Zinner syndrome and underwent aspiration of SV abscess. To the best of our knowledge, such varying presentations of Zinner syndrome have been rarely reported thus far.

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