scholarly journals Heart Dissemination: A Clinical Case of Melanoma

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Diogo André ◽  
Teresa André ◽  
Fabiana Gouveia ◽  
Rafael Nascimento ◽  
António Chaves ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Malignant Melanoma ◽  
Epigastric Pain ◽  
Surgical Excision ◽  
Abdominal Ultrasound ◽  
Melanoma Metastasis ◽  
Diagnostic Challenge ◽  
Cardiac Symptoms ◽  
Large Pericardial Effusion ◽  
History Of

Introduction. Primitive malignant heart tumours are rare, specific cases. The presence of cardiac metastases, often in the pericardium, besides indicating disseminated oncological disease, represents a diagnostic challenge since they tend to be asymptomatic. Malignant cutaneous melanoma (MCM) is the neoplasm that most often affects the heart. Patients and Methods. The authors describe a case report of a 59-year-old female patient with a history of non-insulin-treated diabetes mellitus, arterial hypertension, dyslipidemia, and remitting cutaneous malignant melanoma who underwent skin excision, lymphadenectomy, and adjuvant chemotherapy in 1996. In April 2014, she resorted to emergency service due to epigastric pain and progressive tiredness. Due to the persistence of the complaints, abdominal ultrasound was performed, which showed a large pericardial effusion, corroborated later by teleradiography and echocardiography. The patient underwent pericardiocentesis, which isolated neoplastic cells. A computed tomography study of the chest, abdomen, and pelvis revealed bilateral and pericardial pleural effusion, as well as alterations suggestive of pericardial and pulmonary metastasis. Later, fine-needle aspiration puncture of the left posterior cervical nodule confirmed histologically malignant melanoma metastasis. Discussion. Given the natural history of melanoma that when metastasized has an overall survival of 15–20% for 5 years, its metastatic spread may occur several years after its surgical excision. Thus, patients with a history of melanoma and heart failure who develop new cardiac symptoms of unknown aetiology should undergo imaging studies such as echocardiography, computed tomography, and magnetic resonance imaging.

Refractory Ascites as the Only Presenting Symptom of Chronic Calcified Constrictive Pericarditis: A Diagnostic Challenge

2014 ◽  
Vol 17 (1) ◽  
pp. 42
Author(s):  
Shi-Min Yuan
Keyword(s):  
Computed Tomography ◽  
Liver Cirrhosis ◽  
Female Patient ◽  
Constrictive Pericarditis ◽  
Delayed Diagnosis ◽  
Young Female ◽  
Refractory Ascites ◽  
Diagnostic Challenge ◽  
Massive Ascites ◽  
History Of

Extracardiac manifestations of constrictive pericarditis, such as massive ascites and liver cirrhosis, often cover the true situation and lead to a delayed diagnosis. A young female patient was referred to this hospital due to a 4-year history of refractory ascites as the only presenting symptom. A diagnosis of chronic calcified constrictive pericarditis was eventually established based on echocardiography, ultrasonography, and computed tomography. Cardiac catheterization was not performed. Pericardiectomy led to relief of her ascites. Refractory ascites warrants thorough investigation for constrictive pericarditis.

Parotid Duct Sialolithiasis in a Dog

2007 ◽  
Vol 43 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Brian J. Trumpatori ◽  
Kyleigh Geissler ◽  
Kyle G. Mathews
Keyword(s):  
Computed Tomography ◽  
Inflammatory Infiltrate ◽  
Surgical Excision ◽  
Histological Evaluation ◽  
Parotid Duct ◽  
Facial Swelling ◽  
History Of ◽  
Mixed Inflammatory Infiltrate ◽  
Glandular Atrophy ◽  
English Bulldog

Computed tomography was used to evaluate a 7-year-old English bulldog with a history of facial swelling and to aid in the diagnosis of parotid duct sialolithiasis. Removal of the sialolith with repair of the duct was not possible because of ductal fibrosis. Histological evaluation revealed glandular atrophy and fibrosis with lymphoplasmacytic inflammation. The parotid duct was ulcerated and fibrotic, with a mixed inflammatory infiltrate. Surgical excision of the parotid duct and salivary gland was curative.

scholarly journals Sequential treatment with secukinumab and ustekinumab in a patient with severe psoriasis and recent history of cerebral malignant melanoma metastasis

2019 ◽  
Vol 7 (7) ◽  
pp. 1350-1351 ◽  
Author(s):  
Misbah N. Ghazanfar ◽  
Tonny Karlsmark ◽  
Patricia Louise Danielsen ◽  
Simon F. Thomsen
Keyword(s):  
Malignant Melanoma ◽  
Severe Psoriasis ◽  
Sequential Treatment ◽  
Recent History ◽  
Melanoma Metastasis ◽  
History Of

scholarly journals Morel-Lavallée lesion in a ‘non-traumatic’ thigh: a diagnostic challenge!

2019 ◽  
Vol 18 (1) ◽  
pp. 145-148
Author(s):  
Devesh Sanjeev Ballal ◽  
Balaji Jayasankar ◽  
Gabriel Rodrigues ◽  
Ranjini Kudva
Keyword(s):  
Soft Tissue ◽  
Medical Science ◽  
Surgical Excision ◽  
Diagnostic Challenge ◽  
Soft Tissue Neoplasm ◽  
Diagnostic Dilemma ◽  
Degloving Injury ◽  
Closed Degloving Injury ◽  
History Of ◽  
Closed Degloving

Background: Morel-Lavallée Lesion (MLL) or Morel-Lavallée Seroma (MLS) is a posttraumatic seroma that occurs following a closed degloving injury. It is very important for trauma surgeons to be aware of this relatively rarely reported entity as early diagnosis increases the likelihood of successful management. Case report: We present a patient, wherein the patient had no history of trivial trauma and presented with a gradually growing swelling of left thigh, that was clinically and radiologically diagnosed as a soft tissue neoplasm, successfully managed by surgical excision and were reported to be a MLS. The clinical diagnostic dilemma was solved by the histopathologist! Conclusion: A differential diagnosis of MLL should be kept in mind in patients presenting with soft tissue swellings. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.145-148

scholarly journals Concomitant bilateral elastofibroma in the infrascapular and gluteal regions: a report of a rare case

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Omran Al Dandan ◽  
Ali Hassan ◽  
Mona Al Muhaish ◽  
Jumanah AlMatrouk ◽  
Haidar Almuhanna ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Surgical Excision ◽  
Elastic Fibers ◽  
Histopathological Diagnosis ◽  
Imaging Features ◽  
Serratus Anterior ◽  
History Of ◽  
Benign Soft Tissue Tumor ◽  
Enhanced Computed Tomography

Abstract Background Elastofibroma is a benign soft tissue tumor characterized by the presence of elastic fibers in a stroma of collagen and mature adipose tissue. It is reported to have a prevalence of 2.73%, as shown by a study through computed tomography (CT) images. However, multiple elastofibromas are uncommon. Case presentation We report a case of concomitant bilateral elastofibroma in the infrascapular and gluteal regions. A 63-year-old male patient presented with a 6-month history of gradually increasing painless swellings in the upper back. On physical examination, firm, painless bilateral infrascapular masses were identified; these masses were more noticeable on forward arm flexion. Contrast-enhanced computed tomography showed well-defined bilateral infrascapular masses deep to the serratus anterior muscles as well as poorly defined bilateral gluteal masses with attenuation similar to that of the adjacent skeletal muscle. Magnetic resonance imaging revealed heterogenous masses with internal fatty streaks, consistent with elastofibroma. The histopathological diagnosis of elastofibroma was established based on the results of image-guided core-needle biopsy. The patient underwent surgical excision of both infrascapular elastofibromas with no post-operative complications. As the gluteal masses were incidental, surgical management was not warranted. Conclusion The presence of multiple elastofibromas is unusual. This report describes a rare case of multiple elastofibromas and its typical imaging features, and alerts us that elastofibromas are not exclusive to the periscapular region.

scholarly journals ANTERIOR ABDOMINAL WALL ENDOMETRIOMA: A DIAGNOSTIC CHALLENGE

2016 ◽  
Vol 3 (2) ◽  
pp. 44-46
Author(s):  
Salamat Khan ◽  
Krishna Bhasyal ◽  
Bhusan Raj Timilsina
Keyword(s):  
Computed Tomography ◽  
Abdominal Wall ◽  
Anterior Abdominal Wall ◽  
Lower Abdominal Pain ◽  
Radical Resection ◽  
Rectus Abdominis Muscle ◽  
Medical Sciences ◽  
Diagnostic Challenge ◽  
History Of

We are reporting a case of abdominal wall endometrioma (AWE) in a 32-year-old woman who had an 8 months history of lower abdominal pain and lump. The physical examination revealed an ill-defined mass without tenderness. Computed tomography (CT) showed an enhancing is odense mass at the level of umbilicus right to mid line in right rectus abdominis muscle. The patient was treated with a wide radical resection with a 1 cm margin. There was no postoperative complication. The histological examination confirmed endometriosis. The patient is now on regular follow-up and doing well without any recurrence, five months after her operation.Journal of Universal College of Medical Sciences (2015) Vol.03 No.02 Issue 10Page: 44-46 

Proximal epithelioid sarcoma after a history of malignant melanoma: a diagnostic challenge

Cytopathology ◽  
2016 ◽  
Vol 28 (4) ◽  
pp. 329-332
Author(s):  
G. Wang ◽  
N. van der Westhuizen ◽  
M. Hyrcza ◽  
K. Pringle ◽  
D. Salina
Keyword(s):  
Malignant Melanoma ◽  
Epithelioid Sarcoma ◽  
Diagnostic Challenge ◽  
History Of

Ciliated Foregut Cyst of the Gallbladder. A Diagnostic Challenge and Management Quandary

2014 ◽  
Vol 23 (2) ◽  
pp. 207-210 ◽  
Author(s):  
Alexandros Giakoustidis ◽  
Dawn Morrison ◽  
Andrew Thillainayagam ◽  
Gordon Stamp ◽  
Vishy Mahadevan ◽  
...  
Keyword(s):  
Therapeutic Strategy ◽  
Serum Bilirubin ◽  
Epigastric Pain ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Abdominal Ultrasound ◽  
Liver Function Tests ◽  
Abnormal Liver Function ◽  
Diagnostic Challenge ◽  
Diagnostic Pathway ◽  
Foregut Cyst

Ciliated foregut cysts are rare anomalies due to aberrant embryological development. Only a small number of gallbladder ciliated foregut cysts have been reported. We report the case of a 29-year-old woman presenting with epigastric pain associated with diarrhoea and vomiting, who was found to have raised serum bilirubin levels and abnormal liver function tests. Following a diagnostic pathway including abdominal ultrasound, magnetic resonance cholangiopancreatography and endoscopic ultrasound the gallbladder cyst was provisionally diagnosed to be a cyst arising from the cystic duct or a duplicated gallbladder. A laparoscopic cholecystectomy was carried out and histopathology identified a ciliated foregut gallbladder cyst. The postoperative course was uneventful. In this report we offer what we believe to be an optimal diagnostic pathway and therapeutic strategy for this rare congenital cyst.

scholarly journals Bednar Tumour Occurring after Malignant Melanoma Excision

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Amedeo Ferlosio ◽  
Monia Di Prete ◽  
Piero Rossi ◽  
Elena Campione ◽  
Augusto Orlandi
Keyword(s):  
Subcutaneous Tissue ◽  
Primary Melanoma ◽  
Dermatofibrosarcoma Protuberans ◽  
Surgical Excision ◽  
Clinical History ◽  
Final Diagnosis ◽  
Melanoma Metastasis ◽  
Spindle Cells ◽  
History Of ◽  
In Transit

We report the case of a seventy-four-year-old man with a slow-growing 2 cm mass on the back that arose near the surgical scar of previously excised melanoma, invasive to a Breslow depth of 3 mm. Preoperative clinical diagnosis was “in-transit” melanoma metastasis. After surgical excision, histopathologic examination revealed a dermal nodular proliferation of spindle cells arranged in storiform pattern, with mild pleomorphism, infiltrating around appendages and into the subcutaneous tissue. Immunohistochemical investigation documented diffuse positivity for CD34 and vimentin of spindle cells. Scattered dendritic cells, containing dark pigment in varying proportion and positive for S100, Melan-A and HMB-45, were also observed. A final diagnosis of Bednar tumour was formulated. Subsequently, the patient developed numerous metastases from the primary melanoma and died after 18 months. Bednar tumour is a rare pigmented variant of dermatofibrosarcoma protuberans of intermediate malignant potential. The presence of pigmented cells in Bednar tumour requires careful differential diagnosis with malignant or benign pigmented skin tumours. The clinical history of a Bednar tumour developing close to the scar of a previous melanoma gives the opportunity of a critical and intriguing discussion about the potential origin of pigmented cells in this rare variant of dermatofibrosarcoma protuberans.

scholarly journals Sinonasal Paraganglioma: A Case Report and Review of Literature

2014 ◽  
Vol 7 (2) ◽  
pp. 87-89 ◽  
Author(s):  
Neelam Wadhwa ◽  
PP Singh ◽  
Vipin Arora ◽  
Pankaj Verma ◽  
Khyati Bhatia
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Nasal Cavity ◽  
Rare Case ◽  
Surgical Excision ◽  
Histopathological Diagnosis ◽  
Rare Tumor ◽  
Review Of Literature ◽  
Diagnostic Challenge ◽  
History Of

ABSTRACT A rare case of sinonasal paraganglioma is described. A 40-year-old female patient presented with 2 years history of unilateral nasal obstruction and bleeding. CT scan demonstrated an expansile enhancing mass involving bilateral ethmoids, right nasal cavity and right maxillary sinus. Histopathological diagnosis was neuroendocrine tumor with possibility of paraganglioma. A subtotal maxillectomy with excision of mass performed. Primary nonchromaffin paraganglioma of nose and paranasal sinus is a very rare tumor, these lesion pose diagnostic challenge to clinicians and pathologist. Only twenty five cases are reported in review of literature. Surgical excision is the mainstay of treatment. How to cite this article Arora V, Verma P, Singh PP, Wadhwa N, Bhatia K. Sinonasal Paraganglioma: A Case Report and Review of Literature. Clin Rhinol An Int J 2014;7(2):87-89.

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