scholarly journals Interpretable Diagnosis for Whole-Slide Melanoma Histology Images Using Convolutional Neural Network

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Peizhen Xie ◽  
Ke Zuo ◽  
Jie Liu ◽  
Mingliang Chen ◽  
Shuang Zhao ◽  
...  

At present, deep learning-based medical image diagnosis had achieved high performance in several diseases. However, the black-box nature of the convolutional neural network (CNN) limits their role in diagnosis. In this study, a novel interpretable diagnosis pipeline using the CNN model was proposed. Furthermore, a sizeable melanoma database that contains 841 digital whole-slide images (WSIs) was built to train and evaluate the model. The model achieved strong melanoma classification ability (0.962 areas under the receiver operating characteristic, 0.887 sensitivity, and 0.925 specificity). Moreover, the proposed model outperformed the existing schemes in terms of accuracy that is 20 pathologists (0.933 vs 0.732 accuracy). Finally, the gradient-weighted class activation mapping (Grad-CAM) method was used to show the inner logic of the proposed model and its feasibility to improve diagnosis process in healthcare. The mechanism of feature heat maps which is visualized through a saliency mapping has demonstrated that features learned or extracted by the proposed model are compatible with the accepted pathological features. Conclusively, the proposed model provides a rapid and accurate diagnosis by locating the distinctive features of melanoma to build doctors’ trust in the CNNs’ diagnosis results.

2021 ◽  
Vol 11 (6) ◽  
pp. 2838
Author(s):  
Nikitha Johnsirani Venkatesan ◽  
Dong Ryeol Shin ◽  
Choon Sung Nam

In the pharmaceutical field, early detection of lung nodules is indispensable for increasing patient survival. We can enhance the quality of the medical images by intensifying the radiation dose. High radiation dose provokes cancer, which forces experts to use limited radiation. Using abrupt radiation generates noise in CT scans. We propose an optimal Convolutional Neural Network model in which Gaussian noise is removed for better classification and increased training accuracy. Experimental demonstration on the LUNA16 dataset of size 160 GB shows that our proposed method exhibit superior results. Classification accuracy, specificity, sensitivity, Precision, Recall, F1 measurement, and area under the ROC curve (AUC) of the model performance are taken as evaluation metrics. We conducted a performance comparison of our proposed model on numerous platforms, like Apache Spark, GPU, and CPU, to depreciate the training time without compromising the accuracy percentage. Our results show that Apache Spark, integrated with a deep learning framework, is suitable for parallel training computation with high accuracy.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2648
Author(s):  
Muhammad Aamir ◽  
Tariq Ali ◽  
Muhammad Irfan ◽  
Ahmad Shaf ◽  
Muhammad Zeeshan Azam ◽  
...  

Natural disasters not only disturb the human ecological system but also destroy the properties and critical infrastructures of human societies and even lead to permanent change in the ecosystem. Disaster can be caused by naturally occurring events such as earthquakes, cyclones, floods, and wildfires. Many deep learning techniques have been applied by various researchers to detect and classify natural disasters to overcome losses in ecosystems, but detection of natural disasters still faces issues due to the complex and imbalanced structures of images. To tackle this problem, we propose a multilayered deep convolutional neural network. The proposed model works in two blocks: Block-I convolutional neural network (B-I CNN), for detection and occurrence of disasters, and Block-II convolutional neural network (B-II CNN), for classification of natural disaster intensity types with different filters and parameters. The model is tested on 4428 natural images and performance is calculated and expressed as different statistical values: sensitivity (SE), 97.54%; specificity (SP), 98.22%; accuracy rate (AR), 99.92%; precision (PRE), 97.79%; and F1-score (F1), 97.97%. The overall accuracy for the whole model is 99.92%, which is competitive and comparable with state-of-the-art algorithms.


Agriculture ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 651
Author(s):  
Shengyi Zhao ◽  
Yun Peng ◽  
Jizhan Liu ◽  
Shuo Wu

Crop disease diagnosis is of great significance to crop yield and agricultural production. Deep learning methods have become the main research direction to solve the diagnosis of crop diseases. This paper proposed a deep convolutional neural network that integrates an attention mechanism, which can better adapt to the diagnosis of a variety of tomato leaf diseases. The network structure mainly includes residual blocks and attention extraction modules. The model can accurately extract complex features of various diseases. Extensive comparative experiment results show that the proposed model achieves the average identification accuracy of 96.81% on the tomato leaf diseases dataset. It proves that the model has significant advantages in terms of network complexity and real-time performance compared with other models. Moreover, through the model comparison experiment on the grape leaf diseases public dataset, the proposed model also achieves better results, and the average identification accuracy of 99.24%. It is certified that add the attention module can more accurately extract the complex features of a variety of diseases and has fewer parameters. The proposed model provides a high-performance solution for crop diagnosis under the real agricultural environment.


2021 ◽  
Vol 11 (15) ◽  
pp. 6845
Author(s):  
Abu Sayeed ◽  
Jungpil Shin ◽  
Md. Al Mehedi Hasan ◽  
Azmain Yakin Srizon ◽  
Md. Mehedi Hasan

As it is the seventh most-spoken language and fifth most-spoken native language in the world, the domain of Bengali handwritten character recognition has fascinated researchers for decades. Although other popular languages i.e., English, Chinese, Hindi, Spanish, etc. have received many contributions in the area of handwritten character recognition, Bengali has not received many noteworthy contributions in this domain because of the complex curvatures and similar writing fashions of Bengali characters. Previously, studies were conducted by using different approaches based on traditional learning, and deep learning. In this research, we proposed a low-cost novel convolutional neural network architecture for the recognition of Bengali characters with only 2.24 to 2.43 million parameters based on the number of output classes. We considered 8 different formations of CMATERdb datasets based on previous studies for the training phase. With experimental analysis, we showed that our proposed system outperformed previous works by a noteworthy margin for all 8 datasets. Moreover, we tested our trained models on other available Bengali characters datasets such as Ekush, BanglaLekha, and NumtaDB datasets. Our proposed architecture achieved 96–99% overall accuracies for these datasets as well. We believe our contributions will be beneficial for developing an automated high-performance recognition tool for Bengali handwritten characters.


Author(s):  
Young Hyun Kim ◽  
Eun-Gyu Ha ◽  
Kug Jin Jeon ◽  
Chena Lee ◽  
Sang-Sun Han

Objectives: This study aimed to develop a fully automated human identification method based on a convolutional neural network (CNN) with a large-scale dental panoramic radiograph (DPR) dataset. Methods: In total, 2,760 DPRs from 746 subjects who had 2 to 17 DPRs with various changes in image characteristics due to various dental treatments (tooth extraction, oral surgery, prosthetics, orthodontics, or tooth development) were collected. The test dataset included the latest DPR of each subject (746 images) and the other DPRs (2,014 images) were used for model training. A modified VGG16 model with two fully connected layers was applied for human identification. The proposed model was evaluated with rank-1, –3, and −5 accuracies, running time, and gradient-weighted class activation mapping (Grad-CAM)–applied images. Results: This model had rank-1,–3, and −5 accuracies of 82.84%, 89.14%, and 92.23%, respectively. All rank-1 accuracy values of the proposed model were above 80% regardless of changes in image characteristics. The average running time to train the proposed model was 60.9 sec per epoch, and the prediction time for 746 test DPRs was short (3.2 sec/image). The Grad-CAM technique verified that the model automatically identified humans by focusing on identifiable dental information. Conclusion: The proposed model showed good performance in fully automatic human identification despite differing image characteristics of DPRs acquired from the same patients. Our model is expected to assist in the fast and accurate identification by experts by comparing large amounts of images and proposing identification candidates at high speed.


2021 ◽  
Vol 16 ◽  
Author(s):  
Di Gai ◽  
Xuanjing Shen ◽  
Haipeng Chen

Background: The effective classification of the melting curve is conducive to measure the specificity of the amplified products and the influence of invalid data on subsequent experiments is excluded. Objective: In this paper, a convolutional neural network (CNN) classification model based on dynamic filter is proposed, which can categorize the number of peaks in the melting curve image and distinguish the pollution data represented by the noise peaks. Method: The main advantage of the proposed model is that it adopts the filter which changes with the input and uses the dynamic filter to capture more information in the image, making the network learning more accurate. In addition, the residual module is used to extract the characteristics of the melting curve, and the pooling operation is replaced with an atrous convolution to prevent the loss of context information. Result: In order to train the proposed model, a novel melting curve dataset is created, which includes a balanced dataset and an unbalanced dataset. The proposed method uses six classification-based assessment criteria to compare with seven representative methods based on deep learning. Experimental results show that proposed method is not only markedly outperforms the other state-of-the-art methods in accuracy, but also has much less running time. Conclusion: It evidently proves that the proposed method is suitable for judging the specificity of amplification products according to the melting curve. Simultaneously, it overcomes the difficulties of manual selection with low efficiency and artificial bias.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Defeng Lv ◽  
Huawei Wang ◽  
Changchang Che

Purpose The purpose of this study is to achieve an accurate intelligent fault diagnosis of rolling bearing. Design/methodology/approach To extract deep features of the original vibration signal and improve the generalization ability and robustness of the fault diagnosis model, this paper proposes a fault diagnosis method of rolling bearing based on multiscale convolutional neural network (MCNN) and decision fusion. The original vibration signals are normalized and matrixed to form grayscale image samples. In addition, multiscale samples can be achieved by convoluting these samples with different convolution kernels. Subsequently, MCNN is constructed for fault diagnosis. The results of MCNN are put into a data fusion model to obtain comprehensive fault diagnosis results. Findings The bearing data sets with multiple multivariate time series are used to testify the effectiveness of the proposed method. The proposed model can achieve 99.8% accuracy of fault diagnosis. Based on MCNN and decision fusion, the accuracy can be improved by 0.7%–3.4% compared with other models. Originality/value The proposed model can extract deep general features of vibration signals by MCNN and obtained robust fault diagnosis results based on the decision fusion model. For a long time series of vibration signals with noise, the proposed model can still achieve accurate fault diagnosis.


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