scholarly journals Clinical Value of Body Mass Index and Waist-Hip Ratio in Clinicopathological Characteristics and Prognosis of Uterine Leiomyomata

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Hanyi Pan ◽  
Feiyong Qin ◽  
Fengyun Deng

Objective. To explore the relationship between body mass index (BMI) and waist-to-hip ratio (WHR) and clinicopathological characteristics and prognosis of uterine leiomyomata (UL). Methods. A retrospective analysis of the clinical data of 133 patients with UL admitted to our hospital from September 2018 to August 2019. According to the BMI standard, the patients were divided into the normal group (n = 32), the super-recombination group (n = 45), and the obesity group (n = 56). According to WHR, the patients were divided into the normal body group (n = 32) and the obesity body group (n = 101). The prognosis of all patients with UL at 3 months postoperatively was evaluated. The relationship between BMI patients and clinical characteristics in different groups was compared, and univariate analysis and multivariate logistic regression model were used to analyze the factors affecting the prognosis of UL patients. Results. The proportion of UL patients in the overweight/obese group was higher than that of the normal group, the proportion of the obese body group was higher than that of the normal body group, and the proportion of the good prognosis group was higher than that of the poor prognosis group ( P < 0.05 ). The difference between the overweight/obese group and the normal group and the obese body group and the normal body group was irregular vaginal bleeding, the number of tumors, and the diameter of the lesion ( P < 0.05 ), and the differences between the degenerations in the obese body group and the normal body group were statistically significant ( P < 0.05 ). Multivariate analysis showed that BMI, WHR, surgical method, and tumor location were all independent risk factors that affected the prognosis of the surgery ( P < 0.05 ). Conclusion. Elevated BMI and WHR can be accompanied by an increased risk of UL. Obesity is a risk factor for UL. Overweight/obese women are more clinically pathological than normal patients, and overweight/obese patients have worse surgical prognosis than normal patients. In order to reduce the prevalence of UL and improve the clinicopathological characteristics and prognosis of patients, clinically obese women should be instructed to use reasonable diet and exercise to control weight.

2018 ◽  
Vol 129 (3) ◽  
pp. 448-458 ◽  
Author(s):  
Alexander J. Butwick ◽  
Cynthia A. Wong ◽  
Nan Guo

Abstract What We Already Know about This Topic What This Article Tells Us That Is New Background Neuraxial labor analgesia may benefit obese women by optimizing cardiorespiratory function and mitigating complications related to emergency general anesthesia. We hypothesized that obese women have a higher rate of neuraxial analgesia compared with nonobese parturients. Methods Using U.S. natality data, our cohort comprised 17,220,680 deliveries, which accounts for 61.5% of 28 million births in the United States between 2009 and 2015. We examined the relationships between body mass index class and neuraxial labor analgesia, adjusting for sociodemographic, antenatal, pregnancy, and peripartum factors. Results The study cohort comprised 17,220,680 women; 0.1% were underweight, 12.7% were normal body mass index, 37% were overweight, and 28.3%, 13.5%, and 8.4% were obesity class I, II, and III, respectively. Rates of neuraxial analgesia by body mass index class were as follows: underweight, 59.7% (9,030/15,128); normal body mass index, 68.1% (1,487,117/2,182,797); overweight, 70.3% (4,476,685/6,368,656); obesity class I, 71.8% (3,503,321/4,881,938); obesity class II, 73.4% (1,710,099/2,330,028); and obesity class III, 75.6% (1,089,668/1,442,133). Compared to women with normal body mass index, the likelihood of receiving neuraxial analgesia was slightly increased for overweight women (adjusted relative risk, 1.02; 95% CI, 1.02 to 1.02), obese class I (adjusted relative risk, 1.04; 95% CI, 1.04 to 1.04), obese class II (adjusted relative risk, 1.05; 95% CI, 1.05 to 1.05), and obese class III (adjusted relative risk, 1.06; 95% CI, 1.06 to 1.06). Conclusions Our findings suggest that the likelihood of receiving neuraxial analgesia is only marginally increased for morbidly obese women compared to women with normal body mass index.


2019 ◽  
Vol 5 (1) ◽  
pp. 162-168
Author(s):  
Didik Rio Pambudi ◽  
Ashon Sa�adi ◽  
Sudjarwo Sudjarwo

Obesity-related to the result of decreased reproduction. Obese women are more prone to abnormal anovulation and uterine bleeding, endometrial hyperplasia/cancer, infertility, miscarriage, and pregnancy complications, compared to women of normal weight. This study aims to determine the levels of anti-Mullerian hormone (AMH) in the serum at various BMI (body mass index), also to determine the relationship and correlation between obesity and AMH levels in serum. The population in the study were women aged 20 years to 40 years with less BMI, Normal BMI and Obesity BMI. The study subjects were women between the ages of 20 to 40 years with a BMI less than 17-19.9, obesity BMI = 25 and normal BMI 20-25 as controls. Height measurement, weight weighing, and BMI calculation carried out according to the standard and subject to approval. Taking blood samples for the examination of AMH levels carried out by the RSKI laboratory (Infection Special Hospital) Airlangga University. The results of the data processed with SPSS 25 with the Shapiro-Wilk normality test and Mann Whitney statistical analysis for different tests and Spearman analysis for the correlation test. The results of the study found homogeneous samples, there were no significant differences between the AMH levels of the less and obese groups with, p = 0.832 (p> 0.05). AMH levels in BMI were less (0.459 � 0.112 ng / mL) than obesity BMI (0.432 � 0.058 ng / mL), so it was concluded that AMH levels did not correlate with less BMI with obesity BMI, with a correlation value (r) = -0.105 (p = 0.643; p> 0.05). The results of this study concluded that body mass index not related and does not correlate with the levels of anti-Mullerian hormone in the serum.


2017 ◽  
Vol 45 ◽  
pp. 72-80 ◽  
Author(s):  
J.-H. Lee ◽  
S.K. Park ◽  
J.-H. Ryoo ◽  
C.-M. Oh ◽  
J.-M. Choi ◽  
...  

AbstractBackground:Although a number of studies have examined the relationship between depression and obesity, it is still insufficient to establish the specific pattern of relationship between depression and body mass index (BMI) categories. Thus, this study was aimed to investigate the relationship between depression and BMI categories.Methods:A cross-sectional study was conducted for a cohort of 159,390 Korean based on Kangbuk Samsung Health Study (KSHS). Study participants were classified into 5 groups by Asian-specific cut-off of BMI (18.5, 23, 25 and 30 kg/m2). The presence of depression was determined by Center for Epidemiologic Studies-Depression scales (CES-D) = 16 and = 25. The adjusted odd ratios (ORs) for depression were evaluated by multiple logistic regression analysis, in which independent variable was 5 categories of BMI and dependent variable was depression. Subgroup analysis was conducted by gender and age.Results:When normal group was set as a reference, the adjusted ORs for depression formed U-shaped pattern of relationship with BMI categories [underweight: 1.31 (1.14–1.50), overweight: 0.94 (0.85–1.04), obese group: 1.01 (0.91–1.12), severe obese group: 1.28 (1.05–1.54)]. This pattern of relationship was more prominent in female and young age group than male and elderly subgroup. BMI level with the lowest likelihood of depression was 18.5 kg/m2 to 25 kg/m2 in women and 23 kg/m2 to 25 kg/m2 in men.Conclusions:There was a U-shaped relationship between depression and BMI categories. This finding suggests that both underweight and severe obesity are associated with the increased risk for depression.


2018 ◽  
Vol 128 (4) ◽  
pp. 774-783 ◽  
Author(s):  
Alexander J. Butwick ◽  
Anisha Abreo ◽  
Brian T. Bateman ◽  
Henry C. Lee ◽  
Yasser Y. El-Sayed ◽  
...  

Abstract Background It is unclear whether obesity is a risk factor for postpartum hemorrhage. The authors hypothesized that obese women are at greater risk of hemorrhage than women with a normal body mass index. Methods The authors conducted a cohort study of women who underwent delivery hospitalization in California between 2008 and 2012. Using multilevel regression, the authors examined the relationships between body mass index with hemorrhage (primary outcome), atonic hemorrhage, and severe hemorrhage (secondary outcomes). Stratified analyses were performed according to delivery mode. Results The absolute event rate for hemorrhage was 60,604/2,176,673 (2.8%). In this cohort, 4% of women were underweight, 49.1% of women were normal body mass index, 25.9% of women were overweight, and 12.7%, 5.2%, and 3.1% of women were in obesity class I, II, and III, respectively. Compared to normal body mass index women, the odds of hemorrhage and atonic hemorrhage were modestly increased for overweight women (hemorrhage: adjusted odds ratio [aOR], 1.06; 99% CI, 1.04 to 1.08; atonic hemorrhage: aOR, 1.07; 99% CI, 1.05 to 1.09) and obesity class I (hemorrhage: aOR, 1.08; 99% CI, 1.05 to 1.11; atonic hemorrhage; aOR, 1.11; 99% CI, 1.08 to 1.15). After vaginal delivery, overweight and obese women had up to 19% increased odds of hemorrhage or atonic hemorrhage; whereas, after cesarean delivery, women in any obesity class had up to 14% decreased odds of severe hemorrhage. Conclusions The authors’ findings suggest that, at most, maternal obesity has a modest effect on hemorrhage risk. The direction of the association between hemorrhage and body mass index may differ by delivery mode.


Diabetes ◽  
1999 ◽  
Vol 48 (2) ◽  
pp. 347-352 ◽  
Author(s):  
S. Guven ◽  
A. El-Bershawi ◽  
G. E. Sonnenberg ◽  
C. R. Wilson ◽  
R. G. Hoffmann ◽  
...  

2020 ◽  
Vol 45 (4) ◽  
pp. 133-139
Author(s):  
Marija Klačar ◽  
Marija Zarić ◽  
Jagoda Popović

INTRODUCTION: The increasing prevalence of chronic kidney disease (CKD) is a major health problem. The prevalence of obesity has also been rapidly increasing worldwide. Few studies have examined the relationship between excess body weight and CKD risk. Aim: To evaluate the possible contribution of increased body mass index (BMI) to impaired renal function in the general population sample. METHODS: The study involved 500 participants older than 30 years (228 men, 272 women, age 57.58±13.68) who visited their general practitioner in Health Center "Dr Simo Milošević". Blood samples, blood pressure anthropometric measures were performed on each participant. Estimated glomerular filtration rate was calculated using the abbreviated equation from MDRD study ("the Modification of Diet in Renal Disease Study") and CKD was defined as eGFR less than 60 ml/min/1.73m². Statistical analysis was performed using SPSS 19.0 software (IBM, Somers, New York, USA). RESULTS: The mean BMI was 25.09±3.54 kg/m² with 0.6% in underweight (BMI<18.5 kg/m²), 17.6% in lower normal (BMI 18.5 to 21.9 kg/m²), 33.2% in upper normal (BMI 22.0 to 24.9 kg/m²) and 48.6% in overweight or obese (BMI>25.0 kg/m²) body mass category. The mean eGFR was 100.33±30.78 ml/min/1.73m² with 112±8.62 in underweight, 116.94±3.8 in lower normal, 102.37±2.39 in upper normal and 92.78±1.72 in overweight or obese category. Estimated GFR values decreased significantly with increasing BMI specially in those in upper normal compared to lower normal (p<0.001) and overweight and obese compared to lower normal body mass category (p<0.001). Compared with participants with lower normal body mass, the non-adjusted odds ratio (OR) for mildly or moderately reduced renal function (eGFR<90 ml/min/1.73m²) was 2.54 (95% CI 1.41-4.56) for upper normal and 3.26 (95% CI 1.88-5.70) for overweight and obese participants. After adjusting for potential confounding variables (age, sex, diabetes mellitus, hypertension, hypercholesterolemia, hypertriglyceridemia and smoking status) or for mildly or moderately reduced renal function was 2.23 (95% CI 1.21-4.10) for upper normal 2.65 (95% CI 1.44-4.87) for overweight or obese participants compared to those in lower normal body mass category. CONCLUSION: Estimated GFR values decreased significantly with increasing BMI specially in those in upper normal compared to lower normal (p<0.001) and overweight and obese compared to lower normal body mass category (p<0.001). This study showed that increasing BMI is strongly associated with decreasing eGFR in the general population. The underlying mechanism behind this association remains to be investigated through prospective population-based studies.


2021 ◽  
Vol 26 (4) ◽  
pp. 4290
Author(s):  
A. L. Kalinkin ◽  
A. S. Sorokin

Aim. To assess the relationship between different types of sleep disorders, sleep-related symptoms and hypertension (HTN).Material and methods. This cross-sectional study based on the online survey of persons aged 18-39 years with a body mass index of 18-25 kg/m2.Results. According to the results, the HTN risk in persons aged 18-39 years with normal body mass index increases 2 or more times in the presence of various types of sleep disorders and related symptoms. The prevalence of HTGN depends on the patient's phenotype, i.e. from a combination of different types of sleep disorders and sleep-related symptoms.Conclusion. Given the widespread prevalence of various sleep disorders, as well as the relationship between sleep disorders and hypertension in young people, it is necessary to develop preventive measures aimed at reducing the HTN risk by restoring healthy sleep. We also suggest that various sleep disorders may be the primary link in the development of essential HTN.


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