scholarly journals A Case of Nasopharyngeal Mycobacteriosis with Bony Erosion of the External Skull Base

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Kohei Matsuo ◽  
Satoshi Tanaka ◽  
Masayuki Sakata ◽  
Hiroki Takeda ◽  
Akihiro Nagata ◽  
...  
Keyword(s):  
Skull Base ◽  
Bone Erosion ◽  
Histopathological Examination ◽  
Bone Destruction ◽  
Mycobacterial Infection ◽  
Asian Woman ◽  
Nerve Paralysis ◽  
Malignant Lesions ◽  
The Right ◽  
Bony Erosion

Primary nasopharyngeal mycobacteriosis is a rare disease. We present a case in which skull base bone erosion appeared and was alleviated during the course of the treatment. Bone complications occur in osteoarticular mycobacteriosis, but their occurrence in primary nasopharyngeal mycobacteriosis has not been reported. A 77-year-old immunocompromised Asian woman presented with a right occipitotemporal headache. An ulcerative mass covered with a thick yellowish discharge was found in the roof and posterior walls of the right nasopharynx. Because histopathological examination indicated the presence of mycobacterial infection, we began using antituberculosis medication for the treatment because of the possibility of primary nasopharyngeal tuberculosis. However, this was followed by glossopharyngeal and vagus nerve paralysis. Computed tomography (CT) showed a diffuse enhancing mucosal irregularity in the nasopharynx with bony erosion of the external skull base. Deep tissue biopsy was repeated to differentiate it from malignant lesions, and drainage of pus from the right nasopharynx was confirmed. Subsequently, the headache, neurological findings, and the yellowish discharge disappeared, and the bony erosion of the external skull base was alleviated. Surgical intervention should also be considered for drug-resistant mycobacteriosis. We concluded that mycobacteriosis should also be considered apart from carcinoma even if CT shows a diffuse enhancing mucosal irregularity with bone destruction in the nasopharynx.

Lymphangioma of the skull base bones leading to cerebrospinal fluid rhinorrhea

2008 ◽  
Vol 2 (4) ◽  
pp. 273-276 ◽  
Author(s):  
Eiji Ito ◽  
Kiyoshi Saito ◽  
Tetsuya Nagatani ◽  
Masaaki Teranishi ◽  
Yuzuru Kamei ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Differential Diagnosis ◽  
Skull Base ◽  
Histopathological Examination ◽  
Bone Destruction ◽  
Lytic Lesion ◽  
Csf Rhinorrhea ◽  
Cerebrospinal Fluid Rhinorrhea ◽  
Csf Leakage ◽  
The Right

Lymphangioma localized to the bones of the skull base is rare. The authors report herein the case of a 5-year-old boy who presented with lymphangioma of the bone, localized to the skull base and leading to cerebrospinal fluid (CSF) rhinorrhea with meningitis. Neuroimaging demonstrated lytic destruction with a cyst in the right middle skull base. The patient was successfully treated with resection of the tumor and prevention of CSF leakage. Histopathological examination revealed a lymphangioma. An enlarging lymphangioma can lead to bone destruction. A differential diagnosis of a lytic lesion for a cyst at the skull base is important for proper case management.

scholarly journals Diagnosis and management of eosinophilic granuloma of the jaw: a case report

2019 ◽  
Vol 67 ◽  
Author(s):  
Marcos Vinícius Mendes DANTAS ◽  
Paloma Beatriz Rosa Nunes de SOUZA ◽  
Marisa Aparecida Cabrini GABRIELLI
Keyword(s):  
Alveolar Bone ◽  
Histopathological Examination ◽  
Eosinophilic Granuloma ◽  
Osteolytic Lesion ◽  
Bone Destruction ◽  
Signs And Symptoms ◽  
Therapeutic Interventions ◽  
Facial Swelling ◽  
Mandibular Body ◽  
The Right

ABSTRACT The eosinophilic granuloma is the most common form of the Langherans’ cell histiocytosis. In the majority of cases it is represented by a unilocular osteolytic lesion which can occur in adults and children. It is an intraosseous destructive lesion characterized by the presence of vast numbers of eosinophils and histiocytes. It can be localized or multifocal. The tumor is more prevalent in the first two decades of life and tends to affect mandibular body and angle. Most frequent signs and symptoms are pain, swelling, ulceration, gingival necrosis, alveolar bone destruction with mobility and loss of teeth. Therapeutic interventions for this pathology are surgical curettage, local radiotherapy and chemotherapy. This article presents the case of a 9-year old patient who came in for treatment with facial swelling, pain, tooth mobility and intraoral ulcer in the vestibular sulcus of the right mandibular angle region. Imaging and incisional biopsy were obtained. After the histopathological examination confirmed the diagnosis of eosinophilic granuloma, the lesion was removed by curettage and a reconstruction titanium plate was inserted to avoid a pathological fracture. After 14 years of follow-up no recurrence was found and mandibular growth was not impaired. A discussion about this type of tumor is presented, based on the current literature.

scholarly journals Cavernous Hemangioma of the Maxillary Sinus with Bone Erosion

2007 ◽  
Vol 86 (9) ◽  
pp. 565-566 ◽  
Author(s):  
Erich Mussak ◽  
Jerry Lin ◽  
Mukesh Prasad
Keyword(s):  
Maxillary Sinus ◽  
Cavernous Hemangioma ◽  
Bone Erosion ◽  
Bone Destruction ◽  
Rare Presentation ◽  
Unusual Location ◽  
Epithelial Tumors ◽  
Ostiomeatal Complex ◽  
The Right

We report a case of cavernous hemangioma originating in the maxillary sinus. This is an unusual location for hemangioma, and this case also had a rare presentation involving bone erosion. The substantial bone destruction and resultant widening of the right ostiomeatal complex made it difficult to differentiate this cavernous hemangioma from malignant epithelial tumors.

scholarly journals CT Imaging of Craniofacial Fibrous Dysplasia

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Zerrin Unal Erzurumlu ◽  
Peruze Celenk ◽  
Emel Bulut ◽  
Yakup Sancar Barıs
Keyword(s):  
Skull Base ◽  
Fibrous Dysplasia ◽  
Panoramic Radiography ◽  
Imaging Technique ◽  
Histopathological Examination ◽  
Bone Dysplasia ◽  
Facial Bones ◽  
Axial Ct ◽  
Maxilla And Mandible ◽  
The Right

Fibrous dysplasia is a benign fibroosseous bone dysplasia that can involve single (monostotic) or multiple (polyostotic) bones. Monostotic form is more frequent in the jaws. It is termed as craniofacial fibrous dysplasia, when it involves, though rarely, adjacent craniofacial bones. A 16-year-old girl consulted for a painless swelling in the right posterior mandible for two years. Panoramic radiography revealed ground-glass ill-defined lesions in the three different regions of the maxilla and mandible. Axial CT scan (bone window) showed multiple lesions involving skull base and facial bones. Despite lesions in the skull base, the patient had no abnormal neurological findings. The lesion was diagnosed as fibrous dysplasia based on radiological and histopathological examination. In this paper, CT findings and differential diagnosis of CFD are discussed. CT is a useful imaging technique for CFD cases.

Isolated tubercular hypoglossal nerve paralysis

2016 ◽  
Vol 47 (3) ◽  
pp. 255-260 ◽  
Author(s):  
JS Thakur ◽  
Naina Verma ◽  
Shobha Mohindroo ◽  
Ramesh K Azad ◽  
NK Mohindroo
Keyword(s):  
Nerve Palsy ◽  
Hypoglossal Nerve ◽  
Soft Tissue Mass ◽  
Histopathological Examination ◽  
Posterior Wall ◽  
Tissue Mass ◽  
Nerve Paralysis ◽  
Hypoglossal Nerve Palsy ◽  
Neurological Finding ◽  
The Right

Hypoglossal nerve palsy is not an uncommon neurological finding but primary nasopharyngeal tuberculosis (TB) presenting as hypoglossal nerve palsy is very rare. A 31-year-old woman presented with headache and progressive tongue deviation towards the right side. Diagnostic nasal endoscopy revealed soft tissue mass lesion on the posterior wall of nasopharynx while MRI revealed isointense tumour in nasopharynx with normal hypoglossal nerve and brain. Histopathological examination found TB. We discuss the clinical challenges and possible pathogenesis of this rare clinical entity.

scholarly journals Extramedullary Plasmacytoma of the Orbit as Initial Presentation of Multiple Myeloma

1970 ◽  
Vol 13 (1) ◽  
pp. 24-26
Author(s):  
Rosniza Abdul Razak ◽  
Thomas Paulraj Thamboo ◽  
Shantha Amrith
Keyword(s):  
Multiple Myeloma ◽  
Histopathological Examination ◽  
Lumbar Vertebra ◽  
Extramedullary Plasmacytoma ◽  
Ocular Motility ◽  
Initial Manifestation ◽  
Orbital Mass ◽  
Temporal Quadrant ◽  
The Right ◽  
Bony Erosion

This report is of a patient with a rare extramedullary plasmacytoma of the orbit as the initial manifestation of systemic multiple myeloma. A 34-year-old otherwise healthy man presented with periorbital pain for 2 weeks with proptosis, diplopia, and limited ocular motility in the left eye. Magnetic resonance imaging showed an extraconal mass at the superotemporal region of the left orbit with bony erosion and an enhancing orbital lesion in the temporal quadrant of the right orbit. Histopathological examination of the orbital mass revealed a plasmacytoma with lambda light chain restriction. Systemic evaluation revealed an immunoglobulin G myeloma with multiple myeloma in the first lumbar vertebra, hypercalcaemia, and renal impairment. Chemotherapy was planned. Plasmacytoma of the orbit is rare and can present as the first manifestation of multiple myeloma. Ophthalmologists should be aware of such a presentation and must act promptly. This report reviews the presenting features.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

OSTEOMYELITIS KRONIS MANDIBULA PASCA EKSTRAKSI GIGI DISERTAI BELL’S PALSY

2019 ◽  
Vol 6 ◽  
pp. 52
Author(s):  
Yayun Siti Rochmah
Keyword(s):  
Facial Nerve ◽  
Panoramic Radiograph ◽  
Surrounding Tissue ◽  
Facial Nerve Paralysis ◽  
Muscle Paralysis ◽  
Nerve Paralysis ◽  
The Right ◽  
Spread Of Infection ◽  
Nerve System ◽  
Intravenous Ketorolac

Background: Chronic osteomyelitis mandibula is one of the complications from dental extraction. Inadequate wound handling can have an impact on the spread of infection in the surrounding tissue like nerve which results in facial nerve paralysis. The purpose is to present a rare case that facilitative nerve paralysis as a result of the spread of osteomyelitis infectionCase Management: A 69 years old woman with chief complains numbness onher lips accompanied by pus out beside the lower teeth. No sistemic disease. Panoramic radiograph showed abnormal bone-like sequester. Extraoral examination appeared the bluish color on the right cheek and there was right facial muscle paralysis. Debridement, sequesterectomy by general anesthesia and medication using ceftriaxone intravenous, ketorolac injection, multivitamin, and corticosteroid, physiotherapy for facial nerve paralyze, also.Discussion: Pathogenesis mandibular osteomyelitis involves contiguous spreadfrom an odontogenic focus infection. The bacteria produce an exotoxin, which, while unable to cross the blood-brain barrier, can have deleterious effects on thePeripheral Nerve System (Fasialis Nerve) in up to 75% of cases, with the severity of presentation correlating with the severity of the infection.Conclusion: Chronic mandibular osteomyelitis can spread the infection to around another anatomy oral cavity like facials nerves.

A prospective observational study on the effectiveness of risk of malignancy index score (RMI 3) in a tertiary care centre in Eastern India

2020 ◽  
Vol 11 (5) ◽  
pp. 54-60
Author(s):  
Apurba Mandal ◽  
Shibram Chattopadhyay ◽  
Sushanta Mondal ◽  
Arunava Biswas
Keyword(s):  
Ovarian Cancer ◽  
Adnexal Mass ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Ca 125 ◽  
Tertiary Care Centre ◽  
Gynecology And Obstetrics ◽  
Risk Of Malignancy ◽  
Malignant Lesions

Background: Adnexal mass is a common presentation in today’s gynecological practice. The incidence of ovarian cancer is increasing day by day and diagnosis is often difficult to be made pre operatively with inadequate surgical exploration is a regular occurrence. Aims and Objectives: To assess and validate the importance of RMI-3 score as pre-operative diagnostic tool of differentiating benign from malignant adnexal mass for starting first line therapy of ovarian cancer and to find out the incidences of ovarian malignancy among study population. Material and Methods: The study was conducted in the Department of Gynecology and Obstetrics on (n=115) patients attending GOPD and indoor with adnexal mass fulfilling the inclusion and exclusion criteria using purposive sampling technique. All the selected cases underwent ultrasonography and serum CA- 125 level estimation necessary for calculating RMI score. A score of >200 was taken as suggestive of malignancy and confirmatory diagnosis was performed by histopathological examination obtained from staging laparotomy of adnexal mass. The individual scores were then correlated with final outcomes with statistical analyses. Results: The study revealed benign ovarian tumors are more under 50 years (78.46%) and patients with normal BMI are diagnosed with maximum of malignancy (n = 28). History of tubal ligation carried less risk of malignancy (p<0.0001). Histologically malignant tumors found mostly in 71.4% postmenopausal group whereas 94.1% benign pathology were present in perimenopausal group and there is no association found between parity and histopathology (p=0.058). Bilateral (p=0.013), multilocular (p=0.000) tumors with solid areas (p<0.0001) and thick papillary projections (p<0.0001) had statistically significant association with malignant lesions. RMI score (>200) had more efficacy than serum CA-125 level (>46) in differentiating malignant lesions from benign one in terms of specificity (96% vs 83.87%) and positive predictive value (95% vs 79.17%). Conclusions: RMI-3 score is a simple, reliable and effective tool in differentiating benign from malignant adnexal masses thereby help in quick referral and management of cases with increase chances of survival of the patients.

Osteosarcoma of the jaws: a literature review

2020 ◽  
Vol 16 ◽  
Author(s):  
Francesco Ricotta ◽  
Massimo Bassi ◽  
Nicola Tomasetti ◽  
Angelo Campobassi ◽  
Vincenzo Maiolo ◽  
...  
Keyword(s):  
Treatment Guidelines ◽  
State Of The Art ◽  
Bone Erosion ◽  
Tumor Resection ◽  
Bone Destruction ◽  
Cell Type ◽  
Complete Tumor Resection ◽  
Predominant Cell Type ◽  
Bone Changes ◽  
Complete Tumor

: Osteosarcoma of the jaws (OSJ) is a relatively rare disease, accounting for between 2% and 10% of all cases of osteosarcoma, it is morphologically and radiologically identical to the trunk and extremity variant, but distinct in several crucial aspects. : The lesion is characterized by sarcomatous cells which produces a variable amount of osteoid bone. It arises centrally within the bone and can be subdivided into osteoblastic, chondroblastic and fibroblastic subtype, depending on the predominant cell type. : Radiographically, these tumors display a spectrum of bone changes from well-demarcated borders to lytic bone destruction with indefinite margins and variable cortical bone erosion or, in some cases, images of sclerotic bone. Therapeutic options for OSJ include surgery, chemotherapy and radiotherapy, which are employed according to age of the patient, histological classification and localization of the tumor. Today there is no a general consensus in the treatment guidelines for the OSJ though surgery represents the key of the treatment. The main prognostic factor deeply influencing the patient's prognosis remains the complete tumor resection with negative surgical margins. : The aim of the present review is to describe the state of the art regarding diagnostic and surgical treatment aspects of the primary osteosarcoma of the jaws.

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