scholarly journals Epidemiological Features and Predictors of Mortality in Patients with COVID-19 with and without Underlying Hypertension

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Leila Moftakhar ◽  
Elahe Piraee ◽  
Mohammad Mohammadi Abnavi ◽  
Parisa Moftakhar ◽  
Habibollah Azarbakhsh ◽  
...  

Backgrounds. Individuals with hypertension are at higher risk of COVID-19 infection and related mortality. This study was carried out to assess the epidemiological features and predictors of mortality in patients with COVID-19 with hypertension. Methods. In this retrospective study, the epidemiological characteristics of two groups of patients with COVID-19 with hypertension (1927) and without hypertension (39030) were compared. Chi-square test was applied to evaluate the differences between qualitative variables in two study groups. Logistic regression was also used to determine predictors of mortality in patients with COVID-19 and in patients with COVID-19 with hypertension. Results. The prevalence of hypertension in patients with COVID-19 was 4.7%, and 24.37% of COVID-19 related deaths occurred in these individuals. The average age of hypertension and nonhypertension patients was 61 and 37 years, respectively. Fever, cough, headache, anorexia, fatigue, and comorbid diseases, such as cardiovascular disease, chronic lung and kidney disease, diabetes, immunodeficiency disease, and thyroid disease, were significantly more frequent in people with hypertension than those without hypertension. The chances of mortality in patient with COVID-19 were 1.8 times higher in individuals with dyspnea, 1.25 in individuals with fever, 1.33 in individuals with cough, 3.6 in patients with hypertension, 2.21 in diabetics, and 2.2 in individuals with cardiovascular disease. Also, individuals with COVID-19 with hypertension that had dyspnea, immunodeficiency, and cardiovascular disease were at higher risk of mortality. Conclusion. Hypertension is a serious threat to patients with COVID-19. Therefore, in order to control these patients more precisely and reduce mortality in them, it is extremely important to develop prevention and treatment strategies.

2021 ◽  
Vol 13 (5) ◽  
pp. 2563
Author(s):  
Małgorzata Ćwiek ◽  
Katarzyna Maj-Waśniowska ◽  
Katarzyna Stabryła-Chudzio

This article undertakes the research problem of the assessment of the significance of poverty as a social challenge for local self-government units, and the differences in the assessment of the incidence of this phenomenon depending on the type of municipality. The authors also analyse the relationships between the ageing of the population and the assessment of the extent of poverty by municipalities. It must be pointed out that the undertaken problem has not been a subject of in-depth analysis thus far. Hence, this article fills the identified research gap in this field. The empirical part is based on the results of our own research, conducted using the Computer-Assisted Web Interview (CAWI) method on a sample of 144 municipalities of the Małopolskie Voivodship (Poland). In order to verify whether there is a relationship between the researched qualitative variables, the chi-square test of independence was used. In order to determine the relationships occurring between the categories of variables characterising the scale of the incidence of poverty and the remaining variables, a correspondence analysis was conducted. The research enabled us to find the issue of poverty to be one of the most important social problems from the point of view of municipalities. It is also worth noting that the degree of ageing in the population has an impact on the assessment of poverty among the elderly.


Revista CEFAC ◽  
2018 ◽  
Vol 20 (1) ◽  
pp. 37-43
Author(s):  
Rafaela Coelho Minsky ◽  
Tayná Castilho ◽  
Roseane Rebelo Silva Meira ◽  
Tatiana Godoy Bobbio ◽  
Camila Isabel Santos Schivinski

ABSTRACT Purpose: to analyze whether deleterious oral habits can influence the number of attempts of forced spirometry maneuvers performed by healthy children. Methods: this observational and cross-sectional analytical study included 149 healthy children aged 6-12 years attending public and private schools in Florianópolis, SC, Brazil. A validated protocol was applied for the analysis of deleterious oral habits. The children were grouped according to the number of spirometry maneuvers needed to achieve successful spirometry results, as follows: G1) children who needed 3 maneuvers; G2) 4 maneuvers; G3) 5-8 maneuvers. Data were analyzed with the Kolmogorov-Smirnov test and the Kruskal-Wallis test was applied to compare quantitative variables between the groups. The Chi-square test was used to assess the association between the groups and qualitative variables. Results: there was no association between the number of attempts and the qualitative variables evaluated by the protocol. There was also no difference between the groups regarding quantitative variables for breastfeeding time, breastfeeding occurrence, use of pacifiers, and thumb sucking. Conclusion: the presence of DOH did not influence the number of forced spirometry maneuvers, performed by the healthy children in this study.


Author(s):  
Etienne Belinga ◽  
Isidore Tompeen ◽  
Claude Cyrille Noa Ndoua ◽  
Junie Metogo Ntsama ◽  
Sandrine Mendibi ◽  
...  

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.


2012 ◽  
Vol 83 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Emanuele Mercuri ◽  
Michele Cassetta ◽  
Costanza Cavallini ◽  
Donatella Vicari ◽  
Rosalia Leonardi ◽  
...  

Abstract Objective: To analyze the prevalence, distribution, clinical features, and relationship with dental anomalies of maxillary canine impaction. Materials and Methods: The complete pretreatment records of 1674 orthodontic patients were examined. Subjects with maxillary impacted canines were divided into two study groups: a palatally displaced canine (PDC) group (114 patients) and a buccally displaced canine (BDC) group (37 patients). These were compared to a control group of 151 patients who were randomly selected from the initial sample without maxillary canine impaction. The significance of associations between canine impaction and dental and clinical features and anomalies was examined with the chi-square test. Results: PDC patients presented with normal overjet and facial profile and a lower degree of dental arch crowding in comparison to the control patients. PDC patients showed a higher prevalence of impaction of other teeth, dental aplasia, transposition, and peg-shaped maxillary lateral incisors (odds ratios 3.3, 2.6, 8.3, and 5.8, respectively). Conclusion: PDC was frequently the only orthodontic problem of patients. BDC group patients did not present with notable differences in clinical and dental features or dental anomalies compared to control subjects.


Author(s):  
Leônidas de Oliveira Neto ◽  
Larissa Praça de Oliveira ◽  
Pedro Moraes Dutra Agrícola ◽  
Vagner Deuel de Oliveira Tavares ◽  
Igor Conterato Gomes ◽  
...  

ABSTRACT Background The diagnosis of sarcopenia is based on the analysis of strength, functionality and muscle mass. The objective was to verify the factors associated with sarcopenia in institutionalized elderly. Methods In total, 219 elderly individuals (≥60 years old) living in long-term institutions in Natal/RN were included in the study. After defining the elderly as sarcopenic or non-sarcopenic, anthropometric, biochemical, sociodemographic and health-related were analyzed. The Student t-test and Mann–Whitney test were used to analyze the quantitative, while the chi-square test was used for the qualitative variables. Finally, Poisson regression was used to provide prevalence ratios for those variables that presented differences in the bivariate analyses. Results Physical capacity and anthropometry were associated with sarcopenia. For each 1 cm of knee height, the elderly presented 2.71% more chance of not having sarcopenia, and eutrophic or overweight individuals (according to BMI) presented 37.71 and 91.81% chances, respectively, of not presenting sarcopenia. Elderly individuals who ambulate have a 30.08% chance of not being considered sarcopenic. In addition, biochemical and anthropometric indicators demonstrated a relationship of sarcopenia with malnutrition. Conclusion Sarcopenia is associated with a loss of body mass, not only selective muscle mass, and greater physical inability to ambulate.


Author(s):  
José Vicente Ríos-Santos ◽  
Gregorio Tello-González ◽  
Pedro Lázaro-Calvo ◽  
Francisco Javier Gil Mur ◽  
Blanca Ríos-Carrasco ◽  
...  

Aim: (PRIMARY) Assess the changes in bone level (6 and 12 months after implant placement) between the test (definitive abutment (DEF)) and control (healing abutment (HEA)) groups. (SECONDARY) Assess the changes in bone level (6 and 12 months after implant placement) between the 1 mm high abutment group and 2 mm abutment group. Evaluate changes in implant stability recorded with analysis of the resonance frequency (RFA) Osstell system, at 6 and 12 months after implant placement, between the control group (HEA) and test (DEF). For the DEF group, the abutment was placed at the time of the surgery and was never removed. For the HEA group, the abutment was removed three times during the manufacture of the crowns. The abutments used were 1 mm high (Subgroup A) and 2 mm high (Subgroup B). Materials and methods: A total of 147 patients were selected between 54.82 ± 11.92 years old. After implant placement, patients were randomly distributed in the DEF and HEA group. After the implant placement, a periapical radiograph was taken to assess the peri-implant bone level; the same procedure was carried out 6 and 12 months post-placement. To compare the qualitative variables between the groups (HEA/DEF), the Chi-square test was used; for quantitative (MANOVA). Results: After a year, the accumulated bone loss was 0.48 ± 0.71 mm for the HEA group and 0.36 ± 0.79 mm for the DEF group, without statistical significance. Differences were only found due to timing (time) between 0 and 6 months (=0.001) and 0 and 12 months (0.001), with no differences attributable to the study groups (DEF and HEA). The accumulated bone loss (1 year) was 0.45 ± 0.78 mm for the 1 mm abutment group and 0.41 ± 0.70 mm for the 2 mm abutment group (p = 0.02). No differences were observed in implant stability between groups. Conclusions: The “One Abutment—One Time” concept does not reduce peri-implant bone loss compared to the connection–disconnection technique. The height of the abutment does influence bone loss: the higher the abutment, the lower the bone loss.


2017 ◽  
Vol 35 (8_suppl) ◽  
pp. 245-245
Author(s):  
Safiya Karim ◽  
Jina Zhang-Salomons ◽  
James Joseph Biagi ◽  
Tim Asmis ◽  
Christopher M. Booth

245 Background: While FOLFIRINOX is a standard treatment option for advanced pancreas cancer there is little data describing utilization and effectiveness in routine clinical practice. Here we report practice patterns and outcomes in the general population of Ontario, Canada. Methods: Using the Ontario Cancer Registry and New Drug Funding Program we identified all patients with pancreas cancer treated with palliative intent gemcitabine or FOLFIRINOX in Ontario during 2006-2014. FOLFIRINOX became available in Ontario’s single-payer health system in November 2011. Gemcitabine cases were classified as pre-FOLFIRINOX era (2006-2010) or post-FOLFIRINOX era (2011-2014). Cases treated with peri-operative chemotherapy were excluded. Comparisons of proportions between study groups were made using the chi-square test. Overall survival (OS) was measured from date of chemotherapy initiation. Results: During 2006-2014, 3826 patients in Ontario were treated with Gemcitabine (n=3042) or FOLFIRINOX (n=784) chemotherapy for advanced pancreas cancer. Uptake of FOLFIRINOX increased from 41% (206/505) of treated cases in 2012 to 56% (274/486) of treated cases in 2014. Among patients treated after 2011, median age was 69 and 63 years for Gemcitabine and FOLFIRINOX respectively (p<0.001). The proportion of treated cases who received FOLFIRINOX varied considerably across geographic regions (from 26% to 58%, p<0.001). Median number of FOLFIRINOX cycles delivered was 6 (median 10 cycles in pivotal RCT). Median OS of patients treated with Gemcitabine was 5.0 months in 2006-2010 and 4.8 months in 2011-2014. Median OS of FOLFIRINOX patients treated in 2011-2014 was 8.2 months (median 11.1 months in pivotal RCT). Conclusions: Use of FOLFIRINOX in the general population has increased since 2011 with a resulting decrease in use of Gemcitabine. However, outcomes achieved with FOLFIRINOX in Ontario demonstrate a substantial efficacy-effectiveness gap between survival in the pivotal clinical trial and survival in routine practice.


2018 ◽  
Vol 10 (8) ◽  
pp. 2688 ◽  
Author(s):  
Joanna Cygler ◽  
Włodzimierz Sroka ◽  
Marina Solesvik ◽  
Katarzyna Dębkowska

The growing importance of cooperative relationships may currently be observed throughout the world. The vast majority of such relationships take the form of coopetition, i.e., the simultaneous existence of cooperation and competition between competitors. Previous research on coopetition characterizes these relationships mostly in the context of the benefits achieved. Researchers emphasize a number of benefits resulting from coopetition, e.g., stimulation of innovations of partners, development of the technology, obtaining complementary resources, entering new markets, or creating new products. However, when deciding to begin coopetition, companies should not only consider the benefits, but also the drawbacks associated with such relationships. This is due to the fact that disadvantages are inherent features of coopetitive relationships between competitors. The relationship between the duration of cooperative relationships in particular areas and the benefits and costs associated with these relationships is scarcely researched. Using a sample of 210 companies operating in the high-tech sector in Poland, we aimed to cover this gap in the knowledge base and to analyze this aspect of coopetition. Several research methods including multidimensional correspondence analysis, correlation analysis of qualitative variables, a chi-square test, multi-table analysis, and association rules were applied. The results of our research showed that coopetition is a viable strategy which contributes to the sustainable development of firms. We also found that the duration of coopetitive relationships in different areas of company activity is related to different types of benefits to collaboration partners.


2021 ◽  
Vol 14 (1) ◽  
pp. 14-21
Author(s):  
Amir Sobhani Eraghi ◽  
Iman Azizpour ◽  
Mikaiel Hajializade

Background: Celecoxib is widely used in post-operative cases because of its ability to reduce postoperative opioid drug use. Currently, the use of this drug is common in post-operative cases. In various studies, pregabalin was used for the management of pain after spinal surgery to reduce the need for opioids. Objectives: Since the treatment of tibia fractures and surgery is painful and has a long-term recovery, this study aimed to compare the effect of two drugs (pregabalin and celecoxib) on pain severity at 24 h postoperatively in patients having tibia fracture surgery. This would mark significant progress in taking the proper drug. Methods: In this probability clinical experiment, the sample consisted of 50 patients scheduled for tibia fractures, who were selected from the table of random numbers. Then, the patients were assigned into two groups: celecoxib (Group C) and pregabalin (Group P). In the first group, celecoxib was administered to patients at 1 h pre-operatively at a dose of 200 mg and 1 h post-operatively at a dose of 200 mg. In the second treatment group, patients received pregabalin at 1 h pre-operatively at a dose of 200 mg and 1 h post-operatively at a dose of 200 mg orally. Then VAS (visual analog scale) scores were recorded at 6, 12, and 24 h after surgery. Finally, using SPSS software, qualitative variables were compared according to their percentage by the Chi-square test. For quantitative analysis of variables, the mean value of each group was calculated. The comparison of means was made by t-test. Results: The VAS score was considerably lower at 24 hours after surgery in the pregabalin group than in the celecoxib-treated group. However, after 6 and 12 h of surgery, no statistically meaningful difference was observed. A less analgesic effect was observed in the group treated with celecoxib than pregabalin, which was statistically significant. Conclusion: Pregabalin improves postoperative pain, and it has more analgesic effects than celecoxib.


2021 ◽  
Vol 9 (11) ◽  
pp. 232596712110434
Author(s):  
Damien Sanfilippo ◽  
Charlotte Beaudart ◽  
Allan Gaillard ◽  
Stephen Bornheim ◽  
Olivier Bruyere ◽  
...  

Background: Despite the many studies on running-related injuries (RRIs), risk factors for injury remain unclear in the literature. Purpose: To investigate the risk factors of RRIs. Study Design: Case-control study; Level of evidence, 3. Methods: An online survey was conducted among 3669 injured and noninjured runners. Injury was defined as pain of various kinds, without attention to its consequences on running practice. The survey included 41 questions on 5 main categories—personal characteristics, daily lifestyle, training and running characteristics, practice of other sporting activities, and prevention habits—as well as information about the occurrence of RRI over the previous 12 months. Continuous and qualitative variables were analyzed by Student t test and chi-square test, respectively. Sixteen variables were selected for multivariate binary logistic analysis. Results: Among the 3669 runners, 1852 (50.5%) reported at least 1 injury over the previous 12 months. Overuse injuries were largely represented (60.6%). The variables associated with RRIs that remained significant in the fully adjusted model were previous injury (odds ratio [OR], 1.62; 95% CI, 1.42-1.86), higher weight (OR, 1.006; 95% CI, 1.00-1.012), competitive running (OR, 1.53; 95% CI, 1.19-1.98), running >2 h/wk (OR, 1.28; 95% CI, 1.01-1.62), running >20 km/wk (OR, 1.25; 95% CI, 1.001-1.55), and stretching before running (OR, 1.46; 95% CI, 1.25-1.71). Conclusion: Previous injury remains the most relevant risk factor for RRIs according to the current study and previous data. Many training characteristics seem to be involved but still have to be confirmed in view of conflicting data in the literature. Further research would help clinicians better understand RRIs and how to prevent them.


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