scholarly journals Effect of Platelet-Rich Plasma on Bone Healing in Immediate Implants Analyzed by Cone Beam Computerized Tomography: A Randomized Controlled Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Aleshba S. Khan ◽  
Naauman Zaheer ◽  
Abdul M. Zaigham ◽  
Maliha Shahbaz ◽  
Usman Zaheer ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Loss ◽  
Platelet Rich Plasma ◽  
Controlled Trial ◽  
Marginal Bone Loss ◽  
Implant Placement ◽  
Significant Difference ◽  
Immediate Implant ◽  
Cone Beam Computerized Tomography ◽  
Functional Loading

The possibility of platelet-rich plasma (PRP) on the improvement of bone and adjacent tissue recovery has previously been validated. However, there is insufficient data supporting the use of platelet-rich plasma to improve the healing of bone and adjacent tissues around an implant in the oral cavity. The purpose of this randomized controlled trial was to observe the effect of platelet-rich plasma (PRP) concentrate on marginal bone loss and bone density around immediate implant placement using Cone Beam Computerized Tomography (CBCT). This clinical study was conducted over a period of six months on 12 subjects, who were equally categorized into two groups. Group I was the control, whereas the subjects in Group II received PRP therapy at the surgical site. All subjects were given a standard treatment with a single implant system (DIO UFII hybrid sandblasted acid-etched implants). Inserted implants were analyzed through CBCT, and records were registered at baseline, at the 12th week before functional loading and the 26th week after functional loading. The bone loss was calculated at the proximal (mesial and distal) side of the implant and bone density at baseline, 12th week, and 26th week after implant placement. SPSS version 23.0 was used for statistical analysis of data. The changes in bone levels were measured and compared between the two groups using the Mann–Whitney U test, with no significant difference. Bone density was analyzed by an independent sample t -test, p value ≤ 0.05 was considered statistically significant. Again, no significant difference in bone density was observed between both groups at all three instances. Therefore, it can be concluded that local injection of PRP after immediate implant placement did not show any decrease in marginal bone loss or improvement in bone density. This trial is registered with NCT04650763.

scholarly journals Trends of Implant Placement in Relation to Crestal Bone Level in a Private Dental Institute

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 358-362
Author(s):  
Rinieshah Nair R Baskran ◽  
Rajendra Prabhu Abhinav ◽  
Murugaiyan Arun ◽  
Balaji Ganesh S
Keyword(s):  
Bone Loss ◽  
Dental Implants ◽  
P Value ◽  
Marginal Bone Loss ◽  
Oral Rehabilitation ◽  
Implant Placement ◽  
Significant Difference ◽  
Bone Level ◽  
Natural Dentition ◽  
Bone Height

Dental implants provide a strong foundation for fixed or removable prosthetic teeth that are made to match natural dentition. It has become an ideal method of oral rehabilitation after missing natural dentition has been recognised as a reliable tool for dental reconstruction and aesthetics. Marginal bone loss is characterized by a reduction in bone loss is characterized by a reduction in bone level both vertically and horizontally. The levels at which dental implants are placed include sub-crystal, equi-crestal, and supra-crestal. The crestal levels affect bone height significantly. Failure to do so will lead to peri-implant bone loss which will affect the implant function and ultimately implant failure. A retrospective study was conducted based on a university setting. 615 patients with 1141 implant sites were reviewed from June 2019 to March 2020. Excel tabulation and SPSS analysis were done for data analysis. There was a statistically significant difference between the variables that included tooth region, crestal relation and site (jaw)—[p-value<0.05] The most common crestal relation of implant placement is equi-crestal implant placement. The assessment of trends of implant placement in relation to crestal bone level shows that equi-crestal implant is the most preferred crestal relation of implant placement in Saveetha Dental College.

scholarly journals The effect of soft tissue augmentation on the clinical and radiographical outcomes following immediate implant placement and provisionalization: a systematic review and meta-analysis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Paolo De Angelis ◽  
Paolo Francesco Manicone ◽  
Edoardo Rella ◽  
Margherita Giorgia Liguori ◽  
Silvio De Angelis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Soft Tissue ◽  
Bone Loss ◽  
Intervention Group ◽  
Tissue Thickness ◽  
Marginal Bone Loss ◽  
Facial Soft Tissue ◽  
Implant Placement ◽  
Soft Tissue Thickness ◽  
Immediate Implant

Abstract Background Nowadays, due to the esthetic and social demands of patients, conventional staged protocols seem to be increasingly replaced by faster, one-step protocols. The purpose of the present systematic review is to assess the peri-implant soft tissue changes after immediate implant placement and provisionalization (IIPP) comparing patients treated with or without a sub-epithelial connective tissue graft (SCTG) when replacing a single tooth in the esthetic region. Methods The present systematic review was written following the PRISMA checklist. Immediate implants placed with a connective tissue graft and without one were compared. The researched primary outcomes were the mid-buccal mucosa level (MBML) facial soft tissue thickness (FSTT) and marginal bone loss (MBL). The weighted mean differences (WMD) were estimated for all three outcomes. Results The change in the mid-buccal mucosa level in the intervention group was significantly higher (WMD 0.54; 95% CI 0.33–0.75), with no indication of heterogeneity (I2 = 16%). The facial soft tissue thickness increased significantly in the intervention group (WMD 0.79; 95% CI 0.37–1.22). The marginal bone loss was significantly higher in the control group (WMD 0.13; 95% CI 0.07–0.18), with no indication of heterogeneity (I2 = 0%). Conclusions The results of the meta-analyses showed a statistically significant reduced change of the marginal bone loss and vestibular recession, as well as higher soft tissue thickness, when a graft was used. The included studies had a short observation time; therefore, studies with longer follow-ups are needed to confirm these findings.

Effect of the Different Implant Protocols on Peri-Implant Bone: A 6-Month Prospective Study in Beagle Dogs

2017 ◽  
Vol 40 (12) ◽  
pp. 701-708
Author(s):  
Dandan Song ◽  
Hui Zheng ◽  
Yan Huang ◽  
Xucheng Ma ◽  
Guowu Ma ◽  
...  
Keyword(s):  
Bone Loss ◽  
Prospective Study ◽  
Immediate Loading ◽  
Intraoral Radiography ◽  
Beagle Dogs ◽  
Marginal Bone Loss ◽  
Implant Placement ◽  
Before And After ◽  
Immediate Implant ◽  
Delayed Implant Placement

Objective To compare the effects of different implant placement and loading protocols on the marginal bone loss (MBL) in beagles by intraoral radiography. Methods and materials 61 dental implants were inserted on 9 beagle dogs at bilateral lower posteriors according to 8 different protocols: immediate implant placement and immediate loading for 3 months (IIP + IL3) or 6 months (IIP + IL6) and unloading (IIP + UL), immediate implant placement and delayed loading for 3 months (IIP + DL3) or 6 months (IIP + DL6), delayed implant placement and immediate loading for 3 months (DIP + IL3) or delayed loading for 3 months (DIP + DL3) and unloading (DIP + UL). Intraoral radiography was performed to analyze the MBL during each surgery, before and after the implant placement and at 3-month intervals after the procedure. Results In total, 57 samples were included. There was less MBL (p<0.05) in the IIP + IL3 group (1.22 ± 0.63 mm) compared to the DIP + IL3 group (1.89 ± 0.9 mm). The longer the loading time, the more bone loss appeared in the IIP + IL group; however, the results were reversed in the IIP + DL group. The MBL during the latter 3-month period was dramatically decreased compared to the former 3-month period in the IIP + DL3 group (p<0.05). Conclusions The IIP + IL group seems superior to the DL protocol and the MBL changed significantly during the first three months and thereafter became stable.

scholarly journals Open-Healing Socket Preservation with a Novel Dense Polytetrafluoroethylene (dPTFE) Membrane: A Retrospective Clinical Study

Medicina ◽  
2020 ◽  
Vol 56 (5) ◽  
pp. 216 ◽  
Author(s):  
Gregor-Georg Zafiropoulos ◽  
Zeljka Kačarević ◽  
Syed Qasim ◽  
Branko Trajkovski
Keyword(s):  
Bone Loss ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Socket Preservation ◽  
Fixed Partial Denture ◽  
Implant Placement ◽  
Retrospective Clinical Study ◽  
Significant Difference ◽  
Socket Healing ◽  
Immediate Implant

Background and objectives: Non-resorbable dense polytetrafluoroethylene (dPTFE) membranes are widely used for regeneration procedures, alone or in combination with particulate materials. The aim of this work was to examine the efficacy of a newly developed dPTFE membrane in the management of extraction socket healing. Materials and Methods: The extraction premolar sockets of 44 patients (20 men and 24 women) were preserved. One group received prosthetic rehabilitation with a fixed partial denture (FPD) (PROS group, N = 19) and a second group received immediate implant placement (IMPL group, N = 25). The PROS group sockets were augmented with a bovine derived xenograft and covered with a newly developed dPTFE membrane prior to FPD rehabilitation. Results: In the IMPL group, socket preservation was combined with immediate implant placement. Before (T0) and 6 months after surgery (T1), horizontal and vertical dimensions were measured with customized stents. No significant differences in alveolar bone loss from T0 to T1 were observed between the PROS and IMPL groups in the horizontal dimension for any tooth type. There was a significant difference in alveolar bone loss from T0 to T1 between the two groups for only single-rooted maxillary premolars in the vertical dimension. Conclusions: The use of the examined new dPTFE membrane consistently led to the preservation of hard tissue in the extraction sites.

scholarly journals Immediate implant placement in anterior teeth with grafting material of autogenous tooth bone vs xenogenic bone

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Dong Wu ◽  
Lin Zhou ◽  
Jichao Lin ◽  
Jiang Chen ◽  
Wenxiu Huang ◽  
...  
Keyword(s):  
Bone Loss ◽  
Bone Defect ◽  
Graft Material ◽  
Bone Change ◽  
Marginal Bone Loss ◽  
Implant Placement ◽  
Anterior Teeth ◽  
Immediate Placement ◽  
Immediate Implant ◽  
Xenogenic Bone

Abstract Background The aim of the study was to compare the efficacy of the autogenous tooth bone and xenogenic bone grafted in immediate implant placement with bone defect. Methods Thirty patients whose compromised anterior teeth need immediate implant placement were enrolled. Autogenous tooth bone made from the extracted teeth by chair-side or the xenogenic bone were used to repaired bone defect. Clinical examination, radiographic assessment about the horizontal bone change in the level of 0 mm, 3 mm and 6 mm below the implant neck and the marginal bone loss were made immediately, 6 and 12 months after implant placement. Questionnaire of the feelings about the surgery were made at the time of removing the sutures. Results All implants achieved the success criteria without any complications at the follow-up period. The percent of the horizontal bone change and the marginal bone loss at 6 and 12 months were almost the same between two groups (P > .05). The horizontal bone loss at the first or the latter 6 months was almost the same (P > .05). But the horizontal bone loss at the 6 mm level was less than the 0 mm and 3 mm levels at 6 and 12 months (P < .05). Meanwhile patients seem more satisfied with the autogenous tooth bone derived from the questionnaire. Conclusion The bone volume change in the facial part of the implant after immediate placement is almost the same between two groups. Providing clinical evidence that the autogenous tooth bone made from compromised tooth can be an acceptable bone graft material.

scholarly journals Immediate implant placement in anterior teeth with grafting material of autogenous tooth bone vs xenogenic bone

2019 ◽  
Author(s):  
Dong Wu ◽  
Lin Zhou ◽  
Jichao Lin ◽  
Jiang Chen ◽  
Wenxiu Huang ◽  
...  
Keyword(s):  
Bone Loss ◽  
Bone Defect ◽  
Graft Material ◽  
Bone Change ◽  
Marginal Bone Loss ◽  
Implant Placement ◽  
Anterior Teeth ◽  
Immediate Placement ◽  
Immediate Implant ◽  
Xenogenic Bone

Abstract Background: The aim of the study was to compare the efficacy of the autogenous tooth bone and xenogenic bone grafted in immediate implant placement with bone defect. Methods: Thirty patients whose compromised anterior teeth need immediate implant placement were enrolled. Autogenous tooth bone made from the extracted teeth by chair-side or the xenogenic bone were used to repaired bone defect. Clinical examination, radiographic assessment about the horizontal bone change in the level of 0mm, 3mm and 6mm below the implant neck and the marginal bone loss were made immediately, 6 and 12 months after implant placement. Questionnaire of feeling was made at the time of removing the sutures. Results: All implants achieved the success criteria without any complications at the follow-up period. The percent of the horizontal bone change and the marginal bone loss at 6 and 12 months were almost the same between two groups (P>.05). The horizontal bone loss at the first or the latter 6 months is almost the same (P>.05). But the horizontal bone loss at the 6 mm level is less than the 0 mm and 3 mm levels at 6 and 12 months (P<.05). Meanwhile patients seem more satisfied with the autogenous tooth bone derived from the questionnaire. Conclusion: The bone volume change in the facial part of the implant after immediate placement is almost the same between two groups. Providing clinical evidence that the autogenous tooth bone made from compromised tooth can be an acceptable bone graft material.

scholarly journals COMPARISON BETWEEN STRONTIUM RANELATE AND METAL SUBSTITUTED HYDROXYAPATITE AS GRAFTING MATERIALS IN TREATMENT OF PERI-IMPLANT BONY DEFECTS WITH IMMEDIATE IMPLANTS (CLINICAL AND EXPERIMENTAL STUDY)

2021 ◽  
Vol 9 (5) ◽  
pp. 46-59
Author(s):  
Islam Kandil ◽  
◽  
Enas Elgendy ◽  
Mohamed Anees ◽  
Omar Khashaba ◽  
...  
Keyword(s):  
Bone Density ◽  
Bone Loss ◽  
Dental Implant ◽  
Strontium Ranelate ◽  
Sample Population ◽  
Implant Stability ◽  
Marginal Bone Loss ◽  
Significant Difference ◽  
Hydroxyl Apatite

Objective:The aim of this study is to compare between both of strontium ranelate and metallic substitute of hydroxyapatite as grafting materials in the treatment of peri-implant bony defects with immediate placement of dental implant in type I extraction sites within maxillary esthetic zone among clinical and experimental levels. This assessment was based on clinical, radiographic and histological studies. Subjects and Methods: The present study was carried on two types of population among both experimental levels on experimental white albinus rabbits and on clinical level among human patients for replacement of non-restorable maxillaryanterior and/or premolar teeth within esthetic zone by immediate implant. A written informed consent was obtained from all patients before their participation in this study.Patients were classified into two groups: the first one was with five patients with non-restorable maxillary anterior or premolar tooth that was treated by an immediately placed implant in conjunction with metallic substituted hydroxyapatite while the second one was treated by an immediately placed implant in conjunction with strontium ranelate as grafting material.The second sample population of study was carried out among ten male white (newzland) experimental rabbits with average body weight between 2.5 and 3 KG and within suitable environmental conditions in Medical Experimental Research Center (MERC) in faculty of medicine, Mansoura University. All rabbits sample was also divided equally and randomly in two groups with five rabbits within each one by the same criteria as mentioned where the first group was composed of five rabbits that received dental implant within intentionally made defect in tibia by trephine bur in conjunction with metallic substituted hydroxyl apatite as grafting material within gap between implant and defect and the second group was with the same criteria and procedures with strontium ranelategafting material within the defect. Pre-oparative photographs and cone beam computed topography (CBCT) were taken for study sample population. Within clinical patients, immediately paced dental implant have been placed in anterior esthetic zone with bone grafting around dental implant according to each group, Immediate CBCT and implant stability measurements has been taken after surgery followed by six months follow-up period to evaluate marginal bone loss, bone density, papillary esthetic score, implant stability and probing depth around dental implants. While within experimental animals trephine bur was used to intentionally create the bony defect that will simulate defect around immediate dental implant with grafting material around according to each group with six months follow-up to evaluate marginal bone loss, implant stability,bone density and for histological examination around implant within grafted area. All data were collected and statistically analyzed. Results:Generally among both clinical and experimental levels within both of clinical patients and experimental rabbits, metal substituted hydroxyl apatite (MSHAP) showed better results with significant difference than that presented in other group that has received Strontium ranelate (Sr) as a grafting material to fill the bony marginal gap around immediate dental implant during six months follow-up study period. Results presented high difference of significance between two groups in experimental and clinical levels in concern with both implant stability, marginal bone loss and even in bone quality and denisty when measured after six months follow-up. On the other hand there was no significant difference in concern with soft tissue response after six months in relation with peri-implant probing depth and MSHAP showed slight better results than that of Sr in records of papillary esthetic scores among clinical patients. Histological results showed better response of surrounding bony tissues towards MSHAP than that of Sr with more affinity of osteoblasts and osteocytes to the site of the grafted area. Conclusions:Metallic substituted hydroxyl-apatite (MSHAP) with its additive magnetic molecules within hydroxyapatite structure has better bony response from surrounding bony tissues than that provided by Strontium Ranelate (Sr) according to bone filling and preservation with less marginal loss, more affinity of new osteoblasts and mature osteocytes, long term implant stability after grafting and better bone density and quality at the grafted area around immediate dental implants in anterior maxillary area.

scholarly journals Immediate implant placement in anterior teeth with grafting material of autogenous tooth bone vs xenogenic bone

2019 ◽  
Author(s):  
Dong Wu ◽  
Lin Zhou ◽  
Jichao Lin ◽  
Jiang Chen ◽  
Wenxiu Huang ◽  
...  
Keyword(s):  
Bone Loss ◽  
Bone Defect ◽  
Graft Material ◽  
Bone Change ◽  
Marginal Bone Loss ◽  
Implant Placement ◽  
Anterior Teeth ◽  
Immediate Placement ◽  
Immediate Implant ◽  
Xenogenic Bone

Abstract Objectives: The aim of the study was to compare the efficacy of the autogenous tooth bone and xenogenic bone grafted in immediate implant placement with bone defect. Material and methods: Thirty patients whose compromised anterior teeth need immediate implant placement were enrolled. Autogenous tooth bone made from the extracted teeth by chair-side or the xenogenic bone were used to repaired bone defect. Clinical examination, radiographic assessment about the horizontal bone change in the level of 0mm, 3mm and 6mm below the implant neck and the marginal bone loss were made immediately, 6 and 12 months after implant placement. Questionnaire of feeling was made at the time of removing the sutures.Results: All implants achieved the success criteria without any complications at the follow-up period. The percent of the horizontal bone change and the marginal bone loss at 6 and 12 months were almost the same between two groups (P>.05). The horizontal bone loss at the first or the latter 6 months is almost the same (P>.05). But the horizontal bone loss at the 6 mm level is less than the 0 mm and 3 mm levels at 6 and 12 months (P<.05). Meanwhile patients seem more satisfied with the autogenous tooth bone derived from the questionnaire.Conclusion: The bone volume change in the facial part of the implant after immediate placement is almost the same between two groups.Clinical Relevance: Providing clinical evidence that the autogenous tooth bone made from compromised tooth can be an acceptable bone graft material.

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