scholarly journals Cutaneous Metastasis vs. Isolated Skin Recurrence of Invasive Breast Carcinoma after Modified Radical Mastectomy

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Reza Hosseinpour ◽  
Mohammad Javad Yavari Barhaghtalab

Background. Five to ten percent of the patients with operable breast cancer develop a chest wall recurrence within 10 years following the mastectomy. One of the most distressing presentations of locally recurrent breast cancer is the appearance of cutaneous metastases. To the best of authors’ knowledge, there is no study distinguishing skin metastasis from local recurrence, so the main aim of this report was to elucidate if these two features are important in the prognosis and management of the disease. Case Presentation. A 51-year-old woman referred to the breast clinic due to a painful mass in the left breast. The patient underwent the modified radical mastectomy (MRM) and left axillary lymph node dissection followed by 30 sessions of radiotherapy and 8 sessions of chemotherapy (T3N1M0, ER−, and HER2+). About 15 months after the surgery, she presented with redness and eruptive lesions over the mastectomy scar that increased in size within a three-month follow-up. Conclusion. Mastectomy is not an absolute cure in the treatment of an invasive breast cancer because almost always, there is a recurrence risk and possibility of metastasis. It is vital to differentiate between local recurrence and skin metastasis because it would alter the overall treatment decision, prognosis, and patient outcomes.

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Adamu Ahmed ◽  
Yahaya Ukwenya ◽  
Adamu Abdullahi ◽  
Iliyasu Muhammad

Male breast cancer is an uncommon disease accounting for only 1% of all breast cancers. We present the evaluation, treatment and outcome of male patients seen with breast cancer in our institution. Male patients that had histological diagnosis of breast cancer from 2001 to 2010 were retrospectively evaluated. After evaluation patients were treated with modified radical mastectomy. Combination chemotherapy was given to patients with positive axillary lymph nodes. Radiotherapy and hormonal therapy were also employed. There were 57 male patients with breast cancer which accounted for 9% of all breast cancers seen during the study period. Their mean age was 59 ± 2.3 years. The mean tumor diameter was 13 ± 2.5 cm. Fifty three (93%) patients presented with advanced disease including 15 with distant metastasis. Four patients with stage II disease were treated with modified radical mastectomy, chemotherapy and tamoxifen. Of the 30 patients with sage III disease that had modified radical mastectomy, complete axillary clearance and tumor free margins were achieved in 25. Overall 21 (36.8%) patients were tumor free at one year. Overall 5-year survival was 22.8%. In conclusion, male patients with breast cancer present with advanced disease which is associated with poor outcome of treatment.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Song Wu ◽  
Zechang Xin ◽  
Daxing Sui ◽  
Zhengli Ou ◽  
Haotian Bai ◽  
...  

AbstractAppropriate drainage duration is vital for the postoperative rehabilitation of patients with breast cancer (BC) undergoing modified radical mastectomy (MRM). To provide better and individualized postoperative management for these patients, this study explored independent predictors of postoperative drainage duration in patients with BC. This was a single-center retrospective cohort study. Patients diagnosed with BC and treated with MRM from May 2016 to April 2020 were randomly divided into training (n = 729) and validation (n = 243) cohorts. Univariate and multivariate Cox analyses revealed that the body mass index, serum albumin level, hypertension, number of total dissected axillary lymph nodes, and ratio of positive axillary lymph nodes were independent predictors of postoperative drainage duration in the training cohort. Based on independent predictors, a nomogram was constructed to predict the median postoperative drainage duration and the probability of retaining the suction drain during this period. This nomogram had good concordance and discrimination both in the training and validation cohorts and could effectively predict the probability of retaining the suction drain during drainage, thus assisting clinicians in predicting postoperative drainage duration and providing individualized postoperative management for patients with BC.


Author(s):  
Waqar M. Naqvi

Breast cancer is the most common disease in females and the major cause of mortality and morbidity. In reality, 1.67 million new cases of breast cancer are diagnosed around the world, with 458,000 deaths per year. Approximately 89 percent of breast cancer survivors live for a minimum of five years after treatment, but adverse effects can last for months or years after surgery. The most common side effects of the upper limb are pain and joint dysfunction, which is described as having a prevalence range of 12 percent to 51 percent for pain and 1.5 percent to 50 percent for joint dysfunction.(1) The mainstay in primary breast cancer care is surgery.(2) To assess the impact of an early recovery program on shoulder mobility, functional ability, postoperative complications such as seroma, hematoma, and wound infection in patients who had undergone a modified radical mastectomy (MRM)and to assess the impact of variables in clinical practice (e.g., age, education, BMI, previous shoulder problems, number of dissected axillary lymph nodes and metastatic lymph nodes, use of postoperative radiotherapy (RT) and chemotherapy on shoulder mobility, functional ability, and lymphedema development), and lymphedema.(3) Any of these symptoms can result in permanent arm dysfunction. Shoulder exercises are widely prescribed to minimize the impairment of mobility and strength as well as to prevent lymphedema. A variety in clinical services has been established which help mostly in improvement of shoulder range of motion while also reducing the risk of secondary lymphedema. This is the case of a 32-year-old female, resident of Dastur Nagar, Amravati. Housewife by occupation. She has swelling in her right breast so she visited a private hospital in Amravati. There she detected a lump in her right breast and the doctor recommended further treatment to visit AVBRH Hospital, Sawangi Meghe, and Wardha. She underwent a modified radical mastectomy. Patients that have had a mastectomy are always at the possibility of experiencing shoulder pain and adhesive capsulitis and require preventative measures.


2009 ◽  
Vol 76 (5) ◽  
pp. 293 ◽  
Author(s):  
Seung Jae Lee ◽  
Seung Oook Hwang ◽  
Jin Hyang Jung ◽  
Ho Yong Park ◽  
Jun Hyuk Lee ◽  
...  

2008 ◽  
Vol 69 (10) ◽  
pp. 2499-2504 ◽  
Author(s):  
Manabu SHIMOMURA ◽  
Naoki KAGAWA ◽  
Masahiro YAMASHITA ◽  
Hideki NAKAHARA ◽  
Takashi URUSHIHARA ◽  
...  

2021 ◽  
pp. 38-38
Author(s):  
Imran Thariq Ajmal ◽  
Aravind Kumar. KR ◽  
Pragadeshwaran. C

62yr old female, known diabetic and hypertension, Post CABG presented with hard, mobile, swelling of size 2×3 cm in upper outer quadrant with Right axillary lymph node enlargement size 1×1 cm diagnosed as Right breast cancer with lymph node enlargement. FNAC of Swelling over right breast shows smear positive for malignancy, Ductal carcinoma of Right breast


1994 ◽  
Vol 30 ◽  
pp. S21
Author(s):  
C.P. Lombardi ◽  
S. Rossi ◽  
S. Minelli ◽  
R. Bellantone ◽  
F. Crucitti

2006 ◽  
Vol 72 (9) ◽  
pp. 798-801
Author(s):  
Matthew Voth ◽  
Raye Budway ◽  
Angela Keleher ◽  
Philip F. Caushaj

Women undergoing breast conservation therapy (BCT) for stage 1 breast cancer have adjuvant external beam radiotherapy (EBR). In addition, the use of brachytherapy radiation is being used. We present two local tumor recurrences for review. Our first patient underwent BCT, sentinel lymph node biopsy (SLNBx) and MammoSite® brachytherapy for a T1N0M0 infiltrating ductal carcinoma (IDC) of the right breast. Pathology: 0.6 cm poorly differentiated ER, PR, and Her-2/ Neu negative IDC. At 18 months, she had palpable axillary lymph nodes. Fine needle aspiration and ultrasound-guided core biopsy of a nodule showed IDC. She underwent modified radical mastectomy (MRM) and EBR. Our second patient underwent BCT, SLNBx, and MammoSite® brachytherapy for a T1N0M0 IDC of the left breast. Pathology: 0.8 cm poorly differentiated, ER+, PR-, and Her-2/Neu negative tumor. At 18 months, a retroareolar mass was detected. Ultrasound guided core needle biopsy showed recurrent IDC. She chose a re-excision and EBR and not MRM. Pathology: 1.3 cm poorly differentiated, ER+, PR-, and Her-2/Neu negative tumor. Our 2 recurrences were >2 cm away from the lumpectomy site and therefor outside the 1 cm treatment plan of the MammoSite® catheter. Both recurrences were biologically identical to the initial tumors and are felt to be local failures rather than new primaries.


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