scholarly journals Cosmetic Syndrome Correction with Calcium Hydroxylapatite-Based Filler in Patients with Connective Tissue Dysplasia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Shirshakova ◽  
Elena Morozova ◽  
Daria Sokolova ◽  
Svetlana Pervykh ◽  
Lyailya Kayumova
Keyword(s):  
Connective Tissue ◽  
Soft Tissues ◽  
Skin Condition ◽  
Skin Aging ◽  
Facial Soft Tissue ◽  
Cosmetic Procedure ◽  
Calcium Hydroxylapatite ◽  
Age Related ◽  
Connective Tissue Dysplasia ◽  
Soft Tissue Changes

Undifferentiated connective tissue dysplasia is one of the most common diseases of nowadays, which does not fit into the group of hereditary syndromes. This condition is diagnosed in 20–50% of the population at any age. The study aimed to correct the facial soft tissues of patients with undifferentiated connective tissue dysplasia through the cosmetic procedure of calcium hydroxylapatite injection. In 2018, a 36-year-old patient addressed the beauty salon with signs of undifferentiated connective tissue dysplasia, such as severe asymmetry of the face, infraorbital and nasolabial sulci, and thin and easily folding skin. Signs were observed from the age of 22, i.e., for 14 years. The therapy was performed using special features of the correction of facial soft tissue changes in patients with connective tissue dysplasia (CTD) using calcium hydroxylapatite-based products (Radiesse®, Merz North America, Inc., USA). Particular attention is given to the need for early correction to prevent premature skin aging related to this condition. After 14 days, a significant improvement of the patient’s skin condition was noted after the passing of two procedures. Her condition was estimated as consistent with T1-2P0G0A1Zh1 P1M1K1 and corresponded to grade I age-related changes in the superficial soft tissues. The performed treatment showed high efficacy in case of mild connective tissue dysplasia diagnosis. The results showed that when collecting information from anamnesis, the diagnostic criteria for dysplasia should be considered. If the criteria are met, the cosmetological correction with collagen stimulators becomes possible.

scholarly journals Three-dimensional evaluation of mid-facial soft tissue changes after expansion using micro-implant-supported maxillary skeletal expander

2020 ◽  
Author(s):  
Hieu Nguyen ◽  
Jeong Won Shin ◽  
Hai-Van Giap ◽  
Ki Beom Kim ◽  
Hwa Sung Chae ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Computerized Tomography ◽  
Soft Tissues ◽  
Cone Beam ◽  
Maxillary Expansion ◽  
Hard Tissue ◽  
Facial Soft Tissue ◽  
Tissue Changes ◽  
Cone Beam Computerized Tomography ◽  
Soft Tissue Changes

Abstract Background The aim of this study was to assess the mid-facial soft tissue changes induced by a micro-implant-supported maxillary skeletal expander in late adolescents and young adults by cone-beam computerized tomography and the correlations between hard and soft tissue changes after expansion with maxillary skeletal expander.Subjects and methods Twenty patients with maxillary transverse deficiency treated with maxillary skeletal expander were selected. Cone-beam computerized tomography images taken before and after expansion were superimposed to measure the changes in soft and hard tissue landmarks.Results Anterior nasal spine, posterior nasal spine, and alveolar bone width were significantly increased after expansion with maxillary skeletal expander (p < 0.05). The average lateral movement of the cheek points was 1.13 ± 0.33 mm (left) and 1.41 ± 0.39 mm (right), while that of the alar curvature points was 1.07 ± 0.72 mm (left) and 1.06 ± 0.68 (right) (p < 0.05). The average forward displacement of the cheek points was 0.42 ± 0.66 mm (left) and 0.60 ± 0.58 mm (right), whereas that of the alar curvature points was 0.80 ± 0.67 mm (left) and 0.68 ± 0.56 mm (right) side (p < 0.05). The average downward movement of the subnasale was 0.40 ± 0.37 mm (p < 0.05). The changes in cheek points and alar curvature points on both sides significantly correlated with hard-tissue changes (p < 0.05).Conclusions Maxillary expansion using maxillary skeletal expander resulted in significant lateral and forward movement of soft tissues of the cheek and alar curvature points on both sides and correlated with the maxillary suture opening at the anterior and posterior nasal spines.

scholarly journals Immunotropic effects of mesotherapy used for correction of age-related skin changes

2021 ◽  
Vol 23 (3) ◽  
pp. 585-592
Author(s):  
L. P. Sizyakina ◽  
I. I. Andrreeva ◽  
A. I. Sergeeva
Keyword(s):  
Hyaluronic Acid ◽  
T Lymphocytes ◽  
Skin Aging ◽  
Cell Populations ◽  
Rapid Progression ◽  
Cosmetic Procedure ◽  
Functional Changes ◽  
Immune Parameters ◽  
Age Related ◽  
Peptide Complexes

Rapid progression of aesthetic medicine is a distinctive feature of present decade. In this area, leading position is taken by injection cosmetology, which is associated with an opportunity of pathogenetic approach to resolution of cosmetic problems primarily caused by skin aging. The most commonly used mesotherapy drugs, along with hyaluronic acid, are vitamins, amino acids, and microelements. Skin aging is associated with quantitative and functional changes in the local immune cell populations. In this case, it is rational to assume distinct effects of peptide complexes upon functional potential of immunocompetent cells. The aim of this study was to analyze time-dependent changes of some immune parameters after mesotherapy with a complex of hyaluronic acid and peptides. The observation group consisted of 26 women who received their course of mesotherapy for the first time. Objective instrumental evaluation of the effect with Aramo Smart Lite device showed that, after mesotherapy, the skin quality was significantly improving in comparison with pre-treatment conditions, due to decreased relief of skin creases and wrinkles, with a tendency for reduction of this effect six months later. When comparing the results of immunological testing in the patients after the course of treatment with the data before starting the therapy, we have found redistribution in the lymphoid cell populations, i.e., increased proportion of T-lymphocytes, decreased amounts of B cells, and CD16+ natural killers. Declined numbers of T-lymphocytes expressing early activation marker were associated with increased proportion of peripheral Treg lymphocytes. We have also detected activation of antibody production which manifested as increased levels of all major classes of serum immunoglobulins. Enhanced spontaneous oxidative activity of neutrophils was also noted. The results of immunological monitoring showed that, three months post-treatment, none of the quantitative and functional parameters of immunity was changed, as compared with the results obtained immediately after ending the mesotherapy. Six months later, however, all these indexes returned to their initial positions assessed before the cosmetic procedure. The changes in systemic immune response following mesotherapy with peptide complexes affect the mechanisms of both innate and acquired immunity, including differentiation of lymphocytes, their regulatory functions and activation potential, and provide modulation of effector reactions. Complete restoration of initial immune parameters is observed within six months.

scholarly journals INFLUENCE OF UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA ON SOLID DYSMORPHOGENESIS AND SOFT TISSUES OF THE HEAD AND KEFALOMETRIC INDICATORS OF RESIDENTS OF THE KHMAO – YUGRA 17–20 YEARS

2021 ◽  
Vol 28 (2) ◽  
pp. 32-38
Author(s):  
Natalya Aleksandrovna Ilyushchenko ◽  
◽  
Vladislav Dmitrievich Zinchenko ◽  
Igor Andreevich Shevnin
Keyword(s):  
Sexual Dimorphism ◽  
Connective Tissue ◽  
Soft Tissues ◽  
Connective Tissue Dysplasia ◽  
The Brain ◽  
Brain Parts ◽  
Khanty Mansi Autonomous

As a result of the study, it was found that 94.4% of boys and girls of Khanty-Mansi Autonomous Okrug – Ugra have signs of dysmorphogenesis of hard and soft tissues of the head. In 76% of the examined, connective tissue dysplasia was established. In representatives with connective tissue dysplasia, the signs of dysmorphogenesis of the facial and brain parts of the head are only combined, have sexual dimorphism and are very diverse, aff ecting all areas of the brain and facial parts of the head. The presence of a dysplastic phenotype does not aff ect individual dimensional characteristics of the brain and facial parts of the head, but it aff ects the morphotypological characteristics of these departments and their gender diff erences.

FACIAL AND DENTAL STATUS OF A HUMAN WITH CONNECTIVE TISSUE DYSPLASIA

2020 ◽  
pp. 95-99
Author(s):  
Korshunov A.S. ◽  
Konev V.P. ◽  
Vagner V.D. ◽  
Kuryatnikov K.N. ◽  
Skurikhina A.P. ◽  
...  
Keyword(s):  
Connective Tissue ◽  
The State ◽  
Dental Status ◽  
Maxillofacial Region ◽  
Age Related ◽  
Comprehensive Examination ◽  
Scientific Fact ◽  
Close Relationship ◽  
Connective Tissue Dysplasia ◽  
Relationship Of

Objective. It is necessary to characterize the state of the dentoalveolar system in case of connective tissue dysplasia at different person's life age periods. Materials and methods. The study involved 200 people with odontogenic pathology. They were diagnosed with connective tissue dysplasia (CTD). All of examinated were divided into 2 equal groups with CTD and without CTD, each into 5 equal subgroups of 30 people, according to age: 15-20, 21-30, 31-40, 41-50, 51-60 years. A comprehensive assessment of CTD determination was carried out using diagnostic tables, including non-syndromic forms, in accordance with the total value (+17 or more) of diagnostic coefficients, calculated using the Kullback criteria. Results. The study of phenotypic, facial signs and dysplastic stigmas in the mouth at different ages with connective tissue dysplasia revealed a close relationship of facial, dental and odontological signs at 15-20, 21-30 years old. The most common dysplastic stigmas at a young age are malocclusion, violation of the teeth shape and position. This scientific fact can be explained by the phenomenon of doubt. Doubt is the accumulation of parents and the emergence of new dysplastic phenomena in the maxillofacial area. At the same time, the presented changes in the mouth indicate a violation of the harmony and architectonics of the dentoalveolar apparatus, associated with the general processes of ossification and development of organs and tissues of the mouth, which occur in combination with large stigmas. Conclusions. A comprehensive examination of the maxillofacial region in patients with connective tissue dysplasia revealed a wide variety of dysplastic changes at 15-20, 21-30 years old: curvature of the spine, arachnodactyly, gothic palate, violation of bite, shape and position of teeth, the presence of diastemas, in contrast from groups 31-40, 41-50, 51-60 years old, where these signs were found in single observations. Age-related variability of the studied morphometric and odontological parameters of teeth 3.8, 4.8, showed a pronounced variability at 15-20, 21-30 years with connective tissue dysplasia.

Metabolic therapy and its role in the complex treatment of connective tissue dysplasia in Pediatric Nephrology

2016 ◽  
Vol 73 (1) ◽  
pp. 131-136 ◽  
Author(s):  
S.L. Nyan'kovskyi ◽  
◽  
O.O. Dobrik ◽  
M.Yu. Іs'kiv ◽  
◽  
...  
Keyword(s):  
Connective Tissue ◽  
Pediatric Nephrology ◽  
Complex Treatment ◽  
Metabolic Therapy ◽  
Connective Tissue Dysplasia
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