scholarly journals A Prediction Model for Cognitive Impairment Risk in Colorectal Cancer after Chemotherapy Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Shu-Ping Zhou ◽  
Su-Ding Fei ◽  
Hui-Hui Han ◽  
Jing-Jing Li ◽  
Shuang Yang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Support Vector Machine ◽  
Logistic Regression ◽  
Cognitive Impairment ◽  
Prediction Model ◽  
Clinical Utility ◽  
Prediction Models ◽  
Predictive Ability ◽  
Support Vector ◽  
Colorectal Cancer Patients

Background. A prediction model can be developed to predict the risk of cancer-related cognitive impairment in colorectal cancer patients after chemotherapy. Methods. A regression analysis was performed on 386 colorectal cancer patients who had undergone chemotherapy. Three prediction models (random forest, logistic regression, and support vector machine models) were constructed using collected clinical and pathological data of the patients. Calibration and ROC curves and C -indexes were used to evaluate the selected models. A decision curve analysis (DCA) was used to determine the clinical utility of the line graph. Results. Three prediction models including a random forest, a logistic regression, and a support vector machine were constructed. The logistic regression model had the strongest predictive power with an area under the curve (AUC) of 0.799. Age, BMI, colostomy, complications, CRA, depression, diabetes, QLQ-C30 score, exercise, hypercholesterolemia, diet, marital status, education level, and pathological stage were included in the nomogram. The C -index (0.826) and calibration curve showed that the nomogram had good predictive ability and the DCA curves indicated that the model had strong clinical utility. Conclusions. A prediction model with good predictive ability and practical clinical value can be developed for predicting the risk of cognitive impairment in colorectal cancer after chemotherapy.

scholarly journals Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits

2020 ◽  
Vol 10 (11) ◽  
pp. 4083-4102
Author(s):  
Abelardo Montesinos-López ◽  
Humberto Gutierrez-Pulido ◽  
Osval Antonio Montesinos-López ◽  
José Crossa
Keyword(s):  
Support Vector Machine ◽  
Prediction Model ◽  
Ridge Regression ◽  
Genomic Prediction ◽  
Prediction Models ◽  
Prediction Performance ◽  
Support Vector ◽  
Successful Implementation ◽  
A Posteriori ◽  
Ordinal Traits

Due to the ever-increasing data collected in genomic breeding programs, there is a need for genomic prediction models that can deal better with big data. For this reason, here we propose a Maximum a posteriori Threshold Genomic Prediction (MAPT) model for ordinal traits that is more efficient than the conventional Bayesian Threshold Genomic Prediction model for ordinal traits. The MAPT performs the predictions of the Threshold Genomic Prediction model by using the maximum a posteriori estimation of the parameters, that is, the values of the parameters that maximize the joint posterior density. We compared the prediction performance of the proposed MAPT to the conventional Bayesian Threshold Genomic Prediction model, the multinomial Ridge regression and support vector machine on 8 real data sets. We found that the proposed MAPT was competitive with regard to the multinomial and support vector machine models in terms of prediction performance, and slightly better than the conventional Bayesian Threshold Genomic Prediction model. With regard to the implementation time, we found that in general the MAPT and the support vector machine were the best, while the slowest was the multinomial Ridge regression model. However, it is important to point out that the successful implementation of the proposed MAPT model depends on the informative priors used to avoid underestimation of variance components.

Establishment of Prediction Models for venous thromboembolism in non-oncological urological inpatients--a single center experience

2020 ◽  
Author(s):  
Kaixuan Li ◽  
Haozhen Li ◽  
Quan Zhu ◽  
Ziqiang Wu ◽  
Zhao Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Venous Thromboembolism ◽  
Prediction Model ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Prediction Models ◽  
Predictive Ability ◽  
Multivariate Logistic Regression Model ◽  
Single Center Experience

Abstract Background To establish prediction models for venous thromboembolism (VTE) in non-oncological urological inpatients. Methods A retrospective analysis of 1453 inpatients was carried out and the risk factors for VTE had been clarified our previous studies. Results Risk factors included the following 5 factors: presence of previous VTE (X1), presence of anticoagulants or anti-platelet agents treatment before admission (X2), D-dimer value (≥ 0.89 µg/ml, X3), presence of lower extremity swelling (X4), presence of chest symptoms (X5). The logistic regression model is Logit (P) = − 5.970 + 2.882 * X1 + 2.588 * X2 + 3.141 * X3 + 1.794 * X4 + 3.553 * X5. When widened the p value to not exceeding 0.1 in multivariate logistic regression model, two addition risk factors were enrolled: Caprini score (≥ 5, X6), presence of complications (X7). The prediction model turns into Logit (P) = − 6.433 + 2.696 * X1 + 2.507 * X2 + 2.817 * X3 + 1.597 * X4 + 3.524 * X5 + 0.886 * X6 + 0.963 * X7. Internal verification results suggest both two models have a good predictive ability, but the prediction accuracy turns to be both only 43.0% when taking the additional 291 inpatients’ data in the two models. Conclusion We built two similar novel prediction models to predict VTE in non-oncological urological inpatients. Trial registration: This trial was retrospectively registered at http://www.chictr.org.cn/index.aspx under the public title“The incidence, risk factors and establishment of prediction model for VTE n urological inpatients” with a code ChiCTR1900027180 on November 3, 2019. (Specific URL to the registration web page: http://www.chictr.org.cn/showproj.aspx?proj=44677).

IMPROVED ITERATIVE PREDICTION FOR MULTIPLE STOP ARRIVAL TIME USING A SUPPORT VECTOR MACHINE

Transport ◽  
2012 ◽  
Vol 27 (2) ◽  
pp. 158-164 ◽  
Author(s):  
Chang-Jiang Zheng ◽  
Yi-Hua Zhang ◽  
Xue-Jun Feng
Keyword(s):  
Support Vector Machine ◽  
Prediction Model ◽  
Arrival Time ◽  
Prediction Models ◽  
Prediction Method ◽  
Support Vector ◽  
Dynamic Algorithm ◽  
Proposed Model ◽  
Speed Prediction ◽  
Two Stages

The paper presents an improved iterative prediction method for bus arrival time at multiple downstream stops. A multiple-stop prediction model includes two stages. At the first stage, an iterative prediction model is developed, which includes a single stop prediction model for arrival time at the immediate downstream stop and an average bus speed prediction model on further segments. The two prediction models are constructed with a support vector machine (SVM). At the second stage, a dynamic algorithm based on the Kalman filter is developed to enhance prediction accuracy. The proposed model is assessed with reference to data collected on transit route No 23 in Dalian city, China. The obtained results show that the improved iterative prediction model seems to be a powerful tool for predicting multiple stop arrival time.

scholarly journals Constructing a Predictive Model of Depression in Chemotherapy Patients with Non-Hodgkin’s Lymphoma to Improve Medical Staffs’ Psychiatric Care

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Cheng Hu ◽  
Qian Li ◽  
Ji Shou ◽  
Feng-xian Zhang ◽  
Xia Li ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Prediction Model ◽  
Risk Prediction ◽  
Logistic Regression Analysis ◽  
Clinical Utility ◽  
Predictive Power ◽  
Depressive Symptomatology ◽  
Predictive Ability ◽  
Chemotherapy Patients

Objectives. Depression is highly prevalent in non-Hodgkin’s lymphoma (NHL) patients undergoing chemotherapy. The social stress associated with malignancy induces neurovascular pathology promoting clinical levels of depressive symptomatology. The purpose of this study was to establish an effective depressive symptomatology risk prediction model to those patients. Methods. This study included 238 NHL patients receiving chemotherapy, 80 of whom developed depressive symptomatology. Different types of variables (sociodemographic, medical, and psychosocial) were entered in the models. Three prediction models (support vector machine-recursive feature elimination model, random forest model, and nomogram prediction model based on logistic regression analysis) were compared in order to select the one with the best predictive power. The selected model was then evaluated using calibration plots, ROC curves, and C -index. The clinical utility of the nomogram was assessed by the decision curve analysis (DCA). Results. The nomogram prediction has the most efficient predictive ability when 10 predictors are included ( AUC = 0.938 ). A nomogram prediction model was constructed based on the logistic regression analysis with the best predictive accuracy. Sex, age, medical insurance, marital status, education level, per capita monthly household income, pathological stage, SSRS, PSQI, and QLQ-C30 were included in the nomogram. The C -index was 0.944, the AUC value was 0.972, and the calibration curve also showed the good predictive ability of the nomogram. The DCA curve suggested that the nomogram had a strong clinical utility. Conclusions. We constructed a depressive symptomatology risk prediction model for NHL chemotherapy patients with good predictive power and clinical utility.

Predictors of remission from body dysmorphic disorder after internet-delivered cognitive behavior therapy: a machine learning approach

2019 ◽  
Author(s):  
Oskar Flygare ◽  
Jesper Enander ◽  
Erik Andersson ◽  
Brjánn Ljótsson ◽  
Volen Z Ivanov ◽  
...  
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Random Forests ◽  
Clinical Utility ◽  
Body Dysmorphic Disorder ◽  
Prediction Models ◽  
Behavioral Therapy ◽  
Learning Approach ◽  
Learning Approaches ◽  
Machine Learning Approach

**Background:** Previous attempts to identify predictors of treatment outcomes in body dysmorphic disorder (BDD) have yielded inconsistent findings. One way to increase precision and clinical utility could be to use machine learning methods, which can incorporate multiple non-linear associations in prediction models. **Methods:** This study used a random forests machine learning approach to test if it is possible to reliably predict remission from BDD in a sample of 88 individuals that had received internet-delivered cognitive behavioral therapy for BDD. The random forest models were compared to traditional logistic regression analyses. **Results:** Random forests correctly identified 78% of participants as remitters or non-remitters at post-treatment. The accuracy of prediction was lower in subsequent follow-ups (68%, 66% and 61% correctly classified at 3-, 12- and 24-month follow-ups, respectively). Depressive symptoms, treatment credibility, working alliance, and initial severity of BDD were among the most important predictors at the beginning of treatment. By contrast, the logistic regression models did not identify consistent and strong predictors of remission from BDD. **Conclusions:** The results provide initial support for the clinical utility of machine learning approaches in the prediction of outcomes of patients with BDD. **Trial registration:** ClinicalTrials.gov ID: NCT02010619.

scholarly journals Predicting Ink Transfer Rate of 3D Additive Printing Using EGBO Optimized Least Squares Support Vector Machine Model

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Shengpu Li ◽  
Yize Sun
Keyword(s):  
Support Vector Machine ◽  
Prediction Model ◽  
Least Squares ◽  
Transfer Rate ◽  
Coefficient Of Determination ◽  
Percentage Error ◽  
Support Vector ◽  
Experimental Sample ◽  
Machine Model ◽  
Ink Transfer

Ink transfer rate (ITR) is a reference index to measure the quality of 3D additive printing. In this study, an ink transfer rate prediction model is proposed by applying the least squares support vector machine (LSSVM). In addition, enhanced garden balsam optimization (EGBO) is used for selection and optimization of hyperparameters that are embedded in the LSSVM model. 102 sets of experimental sample data have been collected from the production line to train and test the hybrid prediction model. Experimental results show that the coefficient of determination (R2) for the introduced model is equal to 0.8476, the root-mean-square error (RMSE) is 6.6 × 10 (−3), and the mean absolute percentage error (MAPE) is 1.6502 × 10 (−3) for the ink transfer rate of 3D additive printing.

scholarly journals An Improved Whale Algorithm for Support Vector Machine Prediction of Photovoltaic Power Generation

Symmetry ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 212
Author(s):  
Yu-Wei Liu ◽  
Huan Feng ◽  
Heng-Yi Li ◽  
Ling-Ling Li
Keyword(s):  
Support Vector Machine ◽  
Prediction Model ◽  
Output Power ◽  
Input Data ◽  
Support Vector Machine Model ◽  
Weather Conditions ◽  
Clean Energy ◽  
Support Vector ◽  
Machine Model ◽  
Photovoltaic Power

Accurate prediction of photovoltaic power is conducive to the application of clean energy and sustainable development. An improved whale algorithm is proposed to optimize the Support Vector Machine model. The characteristic of the model is that it needs less training data to symmetrically adapt to the prediction conditions of different weather, and has high prediction accuracy in different weather conditions. This study aims to (1) select light intensity, ambient temperature and relative humidity, which are strictly related to photovoltaic output power as the input data; (2) apply wavelet soft threshold denoising to preprocess input data to reduce the noise contained in input data to symmetrically enhance the adaptability of the prediction model in different weather conditions; (3) improve the whale algorithm by using tent chaotic mapping, nonlinear disturbance and differential evolution algorithm; (4) apply the improved whale algorithm to optimize the Support Vector Machine model in order to improve the prediction accuracy of the prediction model. The experiment proves that the short-term prediction model of photovoltaic power based on symmetry concept achieves ideal accuracy in different weather. The systematic method for output power prediction of renewable energy is conductive to reducing the workload of predicting the output power and to promoting the application of clean energy and sustainable development.

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