scholarly journals Effects of Implant Surface Debridement and Systemic Antibiotics on the Clinical and Microbiological Variables of Periimplantitis

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Muhammad Irshad ◽  
Mohammad Khursheed Alam ◽  
Sajid Ali ◽  
Ahmad Alawneh ◽  
Mohammed Alhadi ◽  
...  
Keyword(s):  
Bone Loss ◽  
Dental Implant ◽  
Implant Surface ◽  
Pocket Depth ◽  
Bleeding On Probing ◽  
Probing Pocket Depth ◽  
Group A ◽  
Group B ◽  
Clinical Records ◽  
Systemic Antibiotics

Objective. To investigate the role of implant surface debridement alone and in conjunction with systemic antibiotics on the clinical and microbiological variables of periimplantitis. Materials and Methods. Data of forty-six patients with at least one dental implant having bleeding-on-probing (BoP), probing pocket depth (PPD) of more than 5 mm, and radiographic bone loss of more than 3 mm were retrieved from clinical records. Data was recorded for dental implant with the deepest PPD, BoP, and bone loss from each patient. “Group-A” received implant surface debridement alone, while “group-B” additionally received systemic antibiotics. Clinical and microbiological data of patients were compared before and after the treatment. Results. At the implant level, a significant reduction of PPD, mucosal recession (MR), and BoP was achieved for all patients. Group B achieved significant improvement in MR and BoP compared to group A at implant level. PPD, MR, and plaque scores showed improvement at implant site level. At 3 months recall visit, 44% of group A and 52% of group B implants required surgical treatment. The presence and proportions of studied bacteria of both groups did not differ significantly at the recall visit when compared to the initial visit. However, P. intermedia and P. micros showed a significant reduction in group A at the recall visit. Conclusions. Implant surface debridement improved the clinical parameters of periimplantitis. In addition, adjunctive use of systemic antibiotics increased mucosal recession and improved bleeding on probing in periimplantitis.

Lack of Clinical Benefit of Implantoplasty to Improve Implant Survival Rate

2020 ◽  
Vol 99 (12) ◽  
pp. 1348-1355 ◽  
Author(s):  
A. Ravidà ◽  
R. Siqueira ◽  
I. Saleh ◽  
M.H.A. Saleh ◽  
A. Giannobile ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Surface Modification ◽  
Survival Rate ◽  
Bone Loss ◽  
Multilevel Regression ◽  
Implant Surface ◽  
Pocket Depth ◽  
Bleeding On Probing ◽  
Probing Pocket Depth ◽  
Implant Therapy

The objective of this study was to compare postsurgical outcomes of resective treatment for peri-implantitis with and without implant surface modification (implantoplasty [IP]). This was accomplished by a retrospective analysis with data from patients with ≥1 implant who were surgically treated for peri-implantitis by resective therapy. Patients were divided into 2 groups regarding treatment approach: IP (test) and no IP (control). Retrospective data were obtained after implant placement (T0) and the day of peri-implantitis surgical treatment (T1). Patients were then recalled (≥1 y after T1) for clinical and radiographic examination (T2). The findings were conclusive. A total of 41 patients (68 implants; mean ± SD follow-up, 41.6 ± 24.4 mo) were included in this study. The survival rate at the implant level was 90% in the test group and 81.6% in the control group ( P > 0.05). Multilevel regression analysis showed that the probability of implant failure was influenced by marginal bone loss (MBL) at T1 and not surgical modality. For example, peri-implantitis defects ≥50% and 25% to 50% MBL were 18.6 and 8.86 times more likely to lose the implant, respectively, when compared with <25% MBL. Nonetheless, MBL changes were similar in the test and control groups ( P = 0.592). Similarly, changes in bleeding on probing, probing pocket depth, and suppuration at T2 did not differ between groups ( P > 0.05). Multilevel regression analysis indicated that clinical improvement of these parameters was influenced by the number of supportive peri-implant therapy visits ( P < 0.01). The results demonstrate little difference between the procedures. Regardless of the implant surface modification (IP) being performed or not, the survival rate of implants treated for peri-implantitis was primarily influenced by the amount of bone loss at the time of treatment. Other clinical parameters (MBL, probing pocket depth, bleeding on probing, suppuration) were influenced by the frequency of supportive peri-implant therapy visits and not by the IP procedure (ClinicalTrials.gov NCT04259840).

scholarly journals Prophylactic temporary abdominal aortic balloon occlusion for patients with pernicious placenta previa: a retrospective study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fei Huo ◽  
Hansheng Liang ◽  
Yi Feng
Keyword(s):  
Placenta Previa ◽  
Balloon Occlusion ◽  
Artery Embolism ◽  
Abdominal Aortic ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Clinical Records ◽  
Group D ◽  
Central Placenta Previa

Abstract Background Pernicious placenta previa (PPP) can increase the risk of perioperative complications. During caesarean section in patients with adherent placenta, intraoperative blood loss, hysterectomy rate and transfusion could be reduced by interventional methods. Our study aimed to investigate the influence of maternal hemodynamics control and neonatal outcomes of prophylactic temporary abdominal aortic balloon (PTAAB) occlusion for patients with pernicious placenta previa. Methods This was a retrospective study using data from the Peking University People’s Hospital from January 2014 through January 2020. Clinical records of pregnant women undergoing cesarean section were collected. Patients were divided into two groups: treatment with PTAAB placement (group A) and no balloon placement (group B). Group A was further broken down into two groups: prophylactic placement (Group C) and balloon occlusion (group D). Results Clinical records of 33 cases from 5205 pregnant women underwent cesarean section were collected. The number of groups A, B, C, and D were 17, 16, 5 and 12.We found that a significant difference in the post-operative uterine artery embolism rates between group A and group B (0% vs.31.3%, p = 0.018). There was a significant difference in the Apgar scores at first minute between group A and group B (8.94 ± 1.43 vs 9.81 ± 0.75,p = 0.037),and the same significant difference between two groups in the pre-operative central placenta previa (29.4% vs. 0%,p = 0.044), complete placenta previa (58.8% vs 18.8%, p = 0.032),placenta implantation (76.5% vs 31.3%, p = 0.015). We could also observe the significant difference in the amount of blood cell (2.80 ± 2.68vs.10.66 ± 11.97, p = 0.038) and blood plasma transfusion (280.00 ± 268.32 vs. 1033.33 ± 1098.20, p = 0.044) between group C and group D. The significant differences in the preoperative vaginal bleeding conditions (0% vs 75%, p = 0.009), the intraoperative application rates of vasopressors (0% vs. 58.3%, p = 0.044) and the postoperative ICU (intensive care unit) admission rates (0% vs. 58.3%, p = 0.044) were also kept. Conclusions PTAAB occlusion could be useful in reducing the rate of post-operative uterine artery embolism and the amount of transfusion, and be useful in coping with patients with preoperative vaginal bleeding conditions, so as to reduce the rate of intraoperative applications of vasopressors and the postoperative ICU (intensive care unit) admission. In PPP patients with placenta implantation, central placenta previa and complete placenta previa, we advocate the utilization of prophylactic temporary abdominal aortic balloon placement.

scholarly journals Evaluation of Bone Mineral Density in Subjects with Primary Hyperparathyroidism by Dual Energy X-Ray Absorptiometry

2018 ◽  
Vol 20 (2) ◽  
pp. 129
Author(s):  
Rezwana Haque ◽  
Raihan Hussain ◽  
Shamim MF Begum
Keyword(s):  
Bone Loss ◽  
Femoral Neck ◽  
Primary Hyperparathyroidism ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
T Score ◽  
Group A ◽  
Group B ◽  
Bone Condition

<p><strong><em>Objective:</em></strong><strong> </strong>Bone loss is a major complication of primary hyperparathyroidism (PHPT), and the extent of bone loss is an important factor for parathyroidectomy. Studies focused on this issue of bone loss in subjects with PHPT are quite rare in our country. This study will help the physicians to take proper action by giving an exact reflection of bone condition in subjects with PHPT. The purpose of this study was to evaluate the bone condition by measuring Bone Mineral Density (BMD), in subjects with PHPT using Dual Energy X-ray Absorptiometry (DEXA) and compare these findings with individuals without PHPT.</p><p><strong><em>Patients and Methods:</em></strong><strong> </strong>It was an analytic cross sectional study (group comparison) carried out at National Institute of Nuclear Medicine and Allied Sciences (NINMAS) BSMMU campus, Dhaka from July 2015-December 2016. Subjects of PHPT diagnosed by biochemical evaluation (increased serum calcium and parathyroid hormone concentrations), between age ranges 15-45 years were selected as group-A. Individuals without biochemical evidence of PHPT or other major illness causing bone loss were selected as comparison group or as group-B. The subjects underwent BMD test by DEXA at lumbar spines from L1-L4 vertebra and the left femoral neck using Norland XR-46 densitometer. BMD was classified according to WHO criteria. Data presented on categorical form were analyzed using chi-squared test. While the data presented on continuous scale were analyzed using student’s t-test. In each analysis, level of significance was 5% and P value &lt;0.05 was considered significant. Data were processed and analyzed with the help of computer software SPSS, version 20.</p><p><strong><em>Results:</em></strong><strong> </strong>Total number of 90 subjects were selected for this study, 45 subjects with PHPT were in group-A and equal number of subjects without PHPT were in group-B. The findings derived from data analysis showed, a significantly more male participants in group-A. The mean age of group-A and group-B was 37.24 ± 8.03 years and 38.20 ± 5.74 years respectively. Mean BMI of group-A was 25.10 ± 4.35 kg/m<sup>2  </sup>in compare to 29.43 ± 5.17 kg/m<sup>2</sup> in group-B. Higher BMI was noted in both groups. PHPT subjects with high BMI had low BMD. BMD expressed in absolute value (gm/cm<sup>2</sup>) and T score. BMD was significantly low in group-A (with PHPT) than in group-B (without PHPT), (p&lt;0.0001). In group-A, prevalence of low BMD was 62.2% (osteopenia 37.8%  and osteoporosis 24.4%)  at lumbar spine and 84.5% (osteopenia 35.6% and osteoporosis 48.9%) at femoral neck. PHPT subjects had significant difference in both T score and BMD between lumbar spine and femoral neck.</p><p><strong><em>Conclusion:</em></strong><strong> </strong>Primary hyperparathyroidism (PHPT) is shown to be associated with significantly reduced BMD especially at femoral neck. Thus, an increased fracture risk should consider if it is left untreated.</p><p>Bangladesh J. Nuclear Med. 20(2): 129-135, July 2017</p>

scholarly journals Does Implant-Abutment Interface affect Marginal Bone Levels around Implants?

2019 ◽  
Vol 13 (01) ◽  
pp. 047-052 ◽  
Author(s):  
Eser Elemek ◽  
Artun Urgancioglu ◽  
Janberd Dincer ◽  
Altug Cilingir
Keyword(s):  
Bone Loss ◽  
Dental Implants ◽  
Marginal Bone Loss ◽  
Single Crown ◽  
Implant Abutment ◽  
Different Types ◽  
Group A ◽  
Group B ◽  
Switch Group

Abstract Objective The use of dental implants with different types of surface roughness and implant-abutment interface has brought about a situation of marginal bone loss. Therefore, the aim of this study was to analyze and compare marginal bone levels of different types of osseointegrated dental implants with platform switch (Group A: Ankylos, Mannheim, Germany) and platform match (Group B: Dentsply Xive, Mannheim, Germany, and Group C: MIS Implant Technologies, Karmiel, Israel). Materials and Methods One hundred and seven patients (52 men and 55 women) with a mean age of 54.79 (standard deviation ± 12.35) years and a total of 321 dental implants (Group A, n = 198; Group B, n = 58; and Group C, n = 65) placed in a private practice between April 2006 and May 2015 were retrospectively analyzed. In addition to demographic information and implant characteristics, marginal bone levels were evaluated by Image J (Wayne Rasband, National Institute of Health, Maryland) program. Results The mean age of all patients was 54.79 ± 12.35 years, and 51.5% of them were women. Implants supporting fixed bridge were most commonly used in all groups (65%), whereas only 20% were restored with a single crown and 15% with overdentures. In total, 47.5% of all implants showed no marginal bone loss. Mean bone loss in Group A was significantly lower (0.81 ± 1.60 mm) as compared to Group B (1.58 ± 1.59 mm) and Group C (1.18 ± 1.36) (p < 0.005). Conclusion Among different types of dental implants, platform switch seems to preserve marginal bone levels and increase the long-term success of dental implants.

scholarly journals The Influence of Prior Hyperthyroidism on Euthyroid Graves’ Ophthalmopathy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Karolien Termote ◽  
Brigitte Decallonne ◽  
Ilse Mombaerts
Keyword(s):  
Thyroid Hormones ◽  
Tsh Receptor ◽  
Thyroid Peroxidase ◽  
Ocular Motility ◽  
Receptor Antibody ◽  
Tsh Receptor Antibody ◽  
Graves Ophthalmopathy ◽  
Group A ◽  
Group B ◽  
Clinical Records

Background. To investigate the influence of previous exposure to elevated thyroid hormones in euthyroid Graves’ ophthalmopathy.Design. Retrospective, observational case series in university setting Median follow-up of 1 year with ranges of 0,8–7,6 years. Study performance of 10 years.Participants. We reviewed the clinical records of 731 Graves’ ophthalmopathy patients. There were 88 (12%) patients with onset of Graves’ ophthalmopathy during euthyroidism: 37 (5%) patients had ophthalmopathy without known history of thyroid dysfunction (group A) and 51 patients (6%) had onset of ophthalmopathy 6 months or more euthyroid after completion of antithyroid therapy (group B).Main Outcome Measures. Graves’ ophthalmopathy was graded using the EUGOGO severity criteria. Unilaterality was investigated. TSH receptor antibody and thyroid peroxidase antibody were measured as markers of Graves’ disease.Results. Group A had more often a normal ocular motility (46%) and less proptosis (14±4 mm) compared to group B (22%,16±4 mm) (P=0.032and 0.028, resp.). TSH receptor antibody was more frequently elevated in group B (94%) than in group A (17%)(P<0.001).Conclusion. Patients with euthyroid Graves’ ophthalmopathy present more often with ocular muscle restriction and proptosis when previously exposed to elevated thyroid hormones.

scholarly journals CORRELATION BETWEEN PERIODONTAL DISEASE INDICES AND LUNG CANCER IN GREEK ADULTS: A CASE — CONTROL STUDY

2016 ◽  
Vol 38 (1) ◽  
pp. 49-53 ◽  
Author(s):  
N A Chrysanthakopoulos
Keyword(s):  
Lung Cancer ◽  
Periodontal Disease ◽  
Case Control Study ◽  
Case Control ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Bleeding On Probing ◽  
Attachment Loss ◽  
Probing Pocket Depth ◽  
Control Study

Aim: The aim of the present case — control study was to examine the possible associations between periodontal disease indices and the risk of lung cancer development in a sample of Greek out-patients referred to a medical and a dental private practice. Materials and Methods: A total of 200 individuals were interviewed and underwent an oral clinical examination, and 64 of them were suffered from several histological types of lung cancer. The estimation of the possible associations between lung cancer as a dependent variable and periodontal disease indices as independent ones was carried out by using a multiple regression analysis model. Results: Probing pocket depth (odds ratio (OR) = 2.72, 95% confidence interval (CI) 1.05–7.06), clinical attachment loss (OR = 3.51, 95% CI 1.30–9.47) bleeding on probing (OR = 1.93, 95% CI 0.98–3.81) were significantly associated with the risk of developing lung cancer. Smoking (OR = 2.49, 95% CI 1.20–5.17) was significantly associated with the mentioned risk, whereas it was consisted as a confounder regarding the estimated associations between moderate/severe clinical attachment loss and presence of bleeding on probing with the risk of developing lung cancer. Conclusion: Probing pocket depth as an index for periodontal disease severity was statistically significantly associated with the risk of developing lung cancer.

scholarly journals Effect of Oxygen Releasing Oral Gel Compared to Chlorhexidine Gel in the Treatment of Periodontitis

2020 ◽  
pp. 75-82
Author(s):  
R. Niveda ◽  
Gurumoorthy Kaarthikeyan
Keyword(s):  
Drug Delivery ◽  
Mean Difference ◽  
Pocket Depth ◽  
Probing Pocket Depth ◽  
Probing Depth ◽  
Group A ◽  
The Mean ◽  
Effect Of Oxygen ◽  
Chlorhexidine Gel ◽  
Depth Reduction

The aim of the current study is to compare the effect of oxygen releasing oral gel and chlorhexidine gel in the treatment of periodontitis and the objective was to assess and compare the changes in clinical parameters such as Probing pocket depth, Bleeding on probing, Clinical attachment levels between oxygen releasing oral gel and chlorhexidine gel. The current pilot study which compares oxygen releasing gel with chlorhexidine gel is a randomised split mouth clinical trial .All the patients included in the study were patients with moderate to severe periodontitis with no systemic diseases, not under any medication non smoking healthy patients. All the patients received supra and sub gingival scaling, pockets on molars with deeper probing depth on either maxillary or mandibular arch and the medication to be received by the patient were allotted randomly. Randomisation was performed using lot method.Oxygen releasing (Blue M gel) and chlorhexidine gel (Hexigel) was applied at the chosen site, patient was recalled for re application and was reassessed  for clinical parameters Paired t test was done to compare the mean difference in probing depth in Blue M gel group and Hexigel group. The mean probing depth at the day of drug delivery was for Blue M gel group was 7.2 mm SD+/-0.42 mm and the mean probing depth six week after drug delivery was 4.7 SD+/- 0.57 mm with a significant p value of 0.42. The mean probing depth at the day of drug delivery was for Hexigel gel group was 7.0 mm SD+/-0.57 mm and the mean probing depth six week after drug delivery was 5.7 SD+/- 0.64 mm. Within the limitations of the study from the results it is seen that there is a significant difference in reduction in probing pocket depth. The mean difference between the  probing depth reduction in group A (Blue M ) from baseline to 6 week was 2.3 and The mean difference probing depth reduction in group B  (Hexigel ) from baseline to 6 week was 1.5. Group A showed better potential in probing depth reduction. It emphasises the fact that thorough sub gingival scaling and root planing along with adjuvant topical oxygen therapy aid in reducing the periodontal pockets further research has to be done to assess the effect of oxygen delivering agents in future.

scholarly journals Comparison of Various Root Planing Instruments: Hand and Ultrasonic—Standard Smooth and Diamond Coated: An in vivo Study

2010 ◽  
Vol 1 (3) ◽  
pp. 149-157 ◽  
Author(s):  
Sushama R Galgali ◽  
NP Rajiv
Keyword(s):  
Statistical Significance ◽  
Root Surface ◽  
Electron Microscopic ◽  
Pocket Depth ◽  
Root Planing ◽  
Group A ◽  
Group B ◽  
Experimental Group ◽  
Scanning Electron

ABSTRACT Aim and objective This study was conducted to evaluate and compare the effectiveness of various root planing instruments, namely the curette, standard smooth ultrasonic tip and diamond coated ultrasonic tip under conditions of nonsurgical root debridement. Materials and methods A total of 20 incisors from 14 patients, with a pocket depth of 5 to 10 mm, indicated for extraction were selected for the study. Teeth selected were randomly assigned to one of the two groups, experimental group A and experimental group B. The proximal surfaces of teeth in experimental group A was instrumented with either Gracey curette or standard smooth ultrasonic tip and in experimental group B with either Gracey curette or diamond coated ultrasonic tip, randomly. Teeth were extracted without injuring the experimental area. The surface area under treatment was photographed at 10X and the percentage of residual calculus was evaluated. Teeth were processed for viewing under scanning electron microscope. Photomicrographs were graded for degree of cleanliness, Remaining Calculus Index (RCI) and Roughness and Loss of Tooth Substance Index (RLTSI) by an independent examiner. Results Percentage of residual calculus as evaluated using stereomicroscope did not show any statistical significance within the groups and among all the three instruments. Scanning electron microscopic assessment for the degree of cleanliness showed better cleanliness for curette compared to standard smooth ultrasonic tip. Remaining calculus was significantly higher for standard smooth ultrasonic tip compared to curette. Diamond coated ultrasonic tip showed greater roughness and loss of tooth substance. Conclusion Within the limits of this in vivo study, diamond coated ultrasonic tip removed a greater amount of root surface and created a rougher surface compared to the curette and standard smooth ultrasonic tip. The amount of root surface removed with diamond coated ultrasonic inserts suggests that they should be used with caution.

scholarly journals Hypertension patients infected with COVID- 19 undergo a longer period of negative conversion:A retrospective study

2020 ◽  
Author(s):  
Bing Xiao ◽  
Dou Fu ◽  
Wei Yang ◽  
Can Zou ◽  
Bing Zhang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Control Group ◽  
History Of ◽  
Group A ◽  
The Mean ◽  
Spss Software ◽  
Group B ◽  
Clinical Records ◽  
Control Group Group ◽  
Negative Conversion

Abstract Purpose Previous studies have showed that age,sex and comorbidities might be associated with severity of patients infected with COVID-19 ,which endangers public health worldwide rapidly.The characteristics and length of negative conversion of Non-severe COVID-19 patients with or without hypertension is limited.This study aims to assess whether non-severe COVID-19 patients with hypertension undergone more longer period of negative conversion .Methods This single-center, retrospective study was performed in Xiantao first People’s Hospital Affiliated to Yangtze University(xiantao, hubei,China) by using medical records.Non-severe COVID-19 patients with a history of hypertension From January 23 to February15 were enrolled as group A. A Control group(group B) was matched (1:1) according to age,sex and the admission date.Data on clinical records, laboratory results, and radiological tests was collected. we conducted all analyses with SPSS software(22.0).Results We enrolled 24 and 24 Non-severe COVID-19 patients with and without hypertension, respectively. The most common symptoms were fever and cough in both groups.The frequency of fatigue is more in patients with hypertension.The levels of AST,ALT and CRP were higher in group A.The mean periods of negative conversion for COVID-19 virus were 17 days(SD:5.5) and 15 days(SD:3.6)for patients with and without hypertension(P=0.021).The mean hospitalization periods were 16.8 days (SD:5.6) and 13.7 days (SD:3.8) , respectively (p=0.083) .Conclusion Non-severe COVID-19 patients with hypertension undergone a longer negative conversion for COVID-19 virus and spent more time on clearing COVID-19 virus.

Efficacy of Acetic Acid Irrigation in Management of Chronic Suppurative Otitis Media “A Prospective Study

2021 ◽  
Vol 15 (10) ◽  
pp. 3300-3303
Author(s):  
Nasir Riaz ◽  
Shakaib Faiz ◽  
Danish Hassnain ◽  
Ayesha Fayyaz ◽  
Tarique Khan ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Acid Versus ◽  
Acid Irrigation ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
Systemic Antibiotics

Background: Prior to surgical management of chronic suppurative otitis media (CSOM) for the dry ear medical management is necessary. CSOM is a biofilm disease and due to this has antibiotic resistance. The pillar of its treatment included aural cleaning according to standard protocols, application of topical germ free antiseptic and use of antimicrobials. Acetic acid due to its ability in reducing the pH may be effective in reducing the growth of microorganisms. Objective: The aim of the study was to compare the efficacy of irrigation with acetic acid versus systemic antibiotics in CSOM patients. Materials & Methods: A total of 134 patients, who came to the ENT department of Sheikh Zayed Hospital, Lahore between 1st April 2020 to 30th September 2020, who had CSOM, of age 15 to 55 years and both genders were included in the study. The patients were divided randomly into two groups. Group A patients received aural toilets and irrigation with acetic acid and Group B received 500 mg of ciprofloxacin twice a day for 2 weeks. Results: The mean age (in years) of the patients in Group A was 37.45±7.32 and in Group B, it was 37.96±7.57. The efficacy of irrigation with acetic acid versus systemic antibiotics was 89.55% and 68.66% respectively and this difference between the two groups was found to be statistically significant (p=0.003). Conclusion: Irrigation with acetic acid was better than systemic antibiotics in managing patients with CSOM. Key words: Acetic acid, CSOM, Middle ear

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