scholarly journals Acute Rheumatic Fever in a COVID-19-Positive Pediatric Patient

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Christa I. DeVette ◽  
Cherise S. Ali ◽  
Devon W. Hahn ◽  
Stephanie D. DeLeon

Bacterial coinfection and COVID-19 have been reported in pediatric populations. We describe a case of Sydenham’s chorea, which is exceedingly rare in developed countries, with concurrent COVID-19. Discussed here is the clinical course of an 8-year-old COVID-positive female with pure Sydenham’s chorea and subclinical carditis from acute rheumatic fever. To our knowledge, there are no documented reports of acute rheumatic fever in a pediatric patient with coexisting COVID-19 infection.

2011 ◽  
Vol 129 (4) ◽  
pp. 267-270
Author(s):  
Rita Santos-Silva ◽  
Susana Corujeira ◽  
Ana Filipe Almeida ◽  
Sofia Granja ◽  
Cláudia Moura ◽  
...  

CONTEXT: Sydenham's chorea affects almost 30% of patients with acute rheumatic fever. It is more frequent in females and is rare in the first decade of life, and genetic vulnerability underlies it. Because of easy access to antibiotics, it is now rare in so-called developed countries. CASE REPORT: A 6-year-old boy with a family history of Huntington's disease, who was the only child of an unscreened and asymptomatic mother, was brought for a consultation because of migratory arthralgia, depressed mood, and rapid, abrupt and unintentional movements of his right arm and leg, that had evolved over a three-week period. On physical examination, he presented a grade III/VI systolic heart murmur and right-side choreic movements, giving rise to a deficit of active mobilization. Laboratory tests revealed elevated erythrocyte sedimentation rate (63 mm/h), C-reactive protein (25 mg/l) and antistreptolysin O titer (1,824 U/ml). Cardiovascular evaluation showed mild aortic insufficiency, moderate mitral insufficiency and a prolonged PR interval. A clinical diagnosis of Sydenham's chorea/acute rheumatic fever was made, and therapy consisting of penicillin, haloperidol, captopril and furosemide was instituted, with excellent results. CONCLUSION: In developed countries, Sydenham's chorea seems forgotten and, because of this, little is known about its clinical course and controversy surrounds the therapeutic options available. This occurrence of rheumatic chorea in a family with Huntington's disease highlights the importance of the differential diagnosis for the different forms of chorea.


2013 ◽  
Vol 9 (1) ◽  
pp. 30-32 ◽  
Author(s):  
PR Regmi ◽  
A Shrestha ◽  
HH Khanal ◽  
BP Nepal ◽  
P Chapagain

Background Sydenham’s Chorea (SC) is a major manifestation of acute rheumatic fever (ARF) and is the only evidence of ARF in approximately 20% of cases. There are no published reports on prevalence of SC in patients with ARF in Nepal. Objectives This retrospective study was done to find out the prevalence of SC in patients with ARF in Nepal. Methods Four years data of 672 patients with ARF from the RF/RHD registry of National RF/RHD prevention & control programme launched by Ministry of Health and Population & Nepal Heart Foundation in 32 hospitals throughout Nepal were analyzed. Results Prevalence of SC as a major manifestation of ARF in Nepalese patients was found to be 3.87%. Females were mostly affected with a female-to-male ratio of 3:1. Patients of age group 10-15 years were affected the most. SC was the third most common manifestation of ARF after Arthritis and Carditis. DOI: http://dx.doi.org/10.3126/njh.v9i1.8345 Nepalese Heart Journal Vol.9(1) 2012 pp.30-32


2015 ◽  
Vol 23 (1) ◽  
pp. 37-40
Author(s):  
Sabiye YILMAZ ◽  
Perihan VARIM ◽  
Murat YILMAZ ◽  
Türkan EĞİLMEZ ACAR ◽  
Mehmet Akif ÇAKAR

PEDIATRICS ◽  
1958 ◽  
Vol 21 (4) ◽  
pp. 582-595
Author(s):  
A. H. Chapman ◽  
Loraine Pilkey ◽  
Mary Jane Gibbons

A psychosomatic study was made of eight children with Sydenham's chorea. The children ranged in age from 7 to 16 years. Three patients had a history of rheumatic fever and three had no evidence of rheumatic disease; in two patients the evidence for rheumatic fever was equivocal, one probably having had it and the other probably not. The eight children were found to be emotionally quite disturbed. Their personality structure was characterized by a triad of (a) marked passivity, (b) schizoid withdrawal from people, with two of the children being frankly schizophrenic, and (c) much underlying anxiety. Obsessive, phobic and depressive features were separately present in some of the children. In five cases the onset of Sydenham's chorea closely followed an episode of marked emotional stress, and in two others the correlation of chorea with emotional stress was equivocal. The literature was reviewed, and it was pointed out that in over half of all reported cases of Sydenham's chorea evidence of rheumatic fever could not be found. It is felt that Sydenham's chorea can be understood only as a psychosomatic illness potentially caused by a number of agents acting individually or jointly, and varying in their respective importance from case to case. Severe personality disorder and rheumatic fever are two such etiologic agents which may be operative in Sydenham's chorea. The importance of further psychosomatic study and experimental psychotherapy in the comprehensive medical study and management of children with this disorder is emphasized.


Cephalalgia ◽  
2005 ◽  
Vol 25 (7) ◽  
pp. 542-544 ◽  
Author(s):  
AL Teixeira ◽  
FC Meira ◽  
DP Maia ◽  
MC Cunningham ◽  
F Cardoso

We compared the frequency of migraine among Sydenham's chorea (SC) patients, rheumatic fever (RF) patients without neurological symptoms and matched controls. Migraine was more frequent in SC patients (12/55, 21.8%) than in controls (9/110, 8.1%) and as common as in the RF group (10/55, 18.2%). Our data are in agreement with previous studies reporting higher frequency of migraine in other basal ganglia disorders, such as essential tremor and Tourette's syndrome.


2010 ◽  
Vol 2 (2) ◽  
pp. 145-146 ◽  
Author(s):  
Madhuri Gawande ◽  
Sunita Ghike ◽  
Sheela Jain

ABSTRACT Chorea Gravidarum is the term given to chorea occurring during pregnancy. It is not an etiologically or pathologically distinct morbid entity but generic term for chorea of any etiology. We report a case of Chorea Gravidarum, who had past history of Rheumatic fever and Sydenham's Chorea in childhood. Factors associated with recurrence of chorea; those aggravating chorea during pregnancy and its management have been discussed.


1968 ◽  
Vol 128 (5) ◽  
pp. 1081-1098 ◽  
Author(s):  
Burton A. Dudding ◽  
Elia M. Ayoub

Antibody levels to streptococcal Group A and A-variant carbohydrates were determined using a radioactive immune precipitation technique on patients with rheumatic fever, with and without valvular disease, on patients with post-streptococcal acute glomerulonephritis, and on age-matched controls. During the acute phase of the above illness, the means of the antibody levels to both carbohydrate antigens were equally elevated and were significantly higher than the normal controls. When Group A antibody levels were determined on sera obtained at intervals of 5–12 months and 1–5 yr after the acute illness) it was found that the antibody levels declined within the normal range at the 5–12 month interval in patients with glomerulonephritis as well as in patients with rheumatic fever in whom no valvular involvement had complicated the disease, i.e., patients with pure Sydenham's chorea. However, in patients with rheumatic valvulitis, who had been on penicillin prophylaxis after the last acute episode, the A antibody level showed little decline from the level obtained during the acute illness. The elevated antibody level in patients with rheumatic valvulitis, including patients with Sydenham's chorea with valvulitis, persisted for periods of at least 1 yr and up to 20 yr after the last acute attack. The pattern of the decline of the antibody levels to the A-variant carbohydrate as well as of the antibody titers to the other streptococcal antigens tested, ASO and anti-DNase B, was similar in all patients studied regardless of the presence of valvular disease. These findings suggest that prolonged persistence of the Group A antibody is a phenomenon peculiar to patients with rheumatic valvular disease. Whether this persistence is involved in the pathogenesis or is an outcome of the valvular disease remains to be determined.


2021 ◽  
Author(s):  
◽  
Melissa Welsh

<p>Acute rheumatic fever is a major cause of heart disease in many parts of the world. Though it is generally considered rare in developed countries, is remains a large issue in New Zealand. Of particular concern is the prevalence of acute rheumatic fever among Maori and Paci c Island peoples. In this thesis we develop a model to simulate acute rheumatic fever in a population. We discuss the use of both deterministic methods and stochastic processes. Demographics and statistics speci c to New Zealand are then used to develop the model in a way that ts speci cally to the situation in New Zealand. We also consider the introduction of treatment strategies for acute rheumatic fever and discuss how risk factors can be used to focus such strategies.</p>


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