scholarly journals The Relieving Effects of a Polyherb-Based Dietary Supplement ColonVita on Gastrointestinal Quality of Life Index (GIQLI) in Older Adults with Chronic Gastrointestinal Symptoms Are Influenced by Age and Cardiovascular Disease: A 12-Week Randomized Placebo-Controlled Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Gang Xu ◽  
Guoqiang Xing ◽  
Bing Zhang ◽  
Jingfen Zhu ◽  
Yong Cai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Controlled Trial ◽  
Gastrointestinal Symptoms ◽  
Old Adults ◽  
Gi Symptoms ◽  
Symptom Scores ◽  
Quality Of Life Index ◽  
Gastrointestinal Quality Of Life ◽  
Giqli Score

Chronic gastrointestinal symptoms (CGS) negatively affect the quality of life in about 15–30% of the population without effective drugs. Recent studies suggest that dietary supplement may improve CGS, but inconsistent results exist. The goal of this study is to evaluate the effect of a polyherbal-based supplement ColonVita on the gastrointestinal quality of life index (GIQLI) in 100 old adults with CGS (63.1 ± 9.6 years) who were randomly assigned to daily ColonVita or placebo tablets (n = 50/group) for 12 weeks in a double-blind, randomized controlled trial design. No significant fibrdifferences were found between ColonVita and placebo in the baseline total GIQLI score (101.12 ± 16.87 vs. 101.80 ± 16.48) ( P > 0.05 ) or postintervention total GIQLI score (114.78 ± 9.62 vs. 111.74 ± 13.01) ( P > 0.05 ). However, ColonVita significantly improved 16 scores of the 19 core GI symptoms compared with 10 items improved by placebo. The ColonVita group significantly improved the remission rate of 5 core GI symptoms compared to placebo and significantly improved the total GIQLI scores (118.09 ± 7.88 vs. 109.50 ± 16.71) ( P < 0.05 ) and core GI symptom scores (64.61 ± 3.99 vs. 60.00 ± 8.65) ( P < 0.05 ) in people ≥60 years of age (n = 49) but not in those under 60 y (n = 51). ColonVita significantly improved the total GIQLI scores and core GI symptom scores in people without cardiovascular diseases (CVD) (n = 56) (116.74 ± 9.38 vs. 110.10 ± 14.28) ( P < 0.05 ) and (63.11 ± 4.53 vs. 59.93 ± 8.03) ( P = 0.07 ), respectively, but not in those with CVD (n = 44). Thus, ColonVita was beneficial for old adults with CGS, especially those ≥60 years of age and without CVD. Because a heterogenous pathogenesis of CGS-like irritable bowel syndrome (IBS) and inflammatory bowel disease (ISD) is differentially associated with CVD, different comorbidities may have influenced the outcomes of different trials that should be controlled in further studies.

Gastrointestinal symptoms of pelvic radiation disease (part 1): literature review

2020 ◽  
Vol 18 (2) ◽  
pp. 40-45 ◽  
Author(s):  
Helen Ludlow ◽  
John Green
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Literature Review ◽  
Patient Experience ◽  
Gastrointestinal Symptoms ◽  
Pelvic Radiation ◽  
Gi Symptoms ◽  
Pelvic Cancer ◽  
The Impact

Radiotherapy used to treat cancers in the pelvic region can have lasting side effects, and the persistence of these symptoms for 3 months or more is described as pelvic radiation disease (PRD). The growing number of pelvic cancer patients being diagnosed and successfully treated is increasing the incidence of PRD. This review examines the literature on the gastrointestinal symptoms of PRD. This includes how PRD is defined, how it is identified and how it relates specifically to the three pelvic cancers in which it most commonly manifests (prostate, gynaecological and colorectal). It pays particular attention to the impact of PRD on patient experience and quality of life. This review is the first part in a series on the GI symptoms of PRD.

Perioperative Outcomes and Quality of Life after Repair of Recurrent Hiatal Hernia are Compromised Compared with Primary Repair

2019 ◽  
Vol 85 (5) ◽  
pp. 556-560 ◽  
Author(s):  
Andrew M. Brown ◽  
Ramzy Nagle ◽  
Michael J. Pucci ◽  
Karen Chojnacki ◽  
Ernest L. Rosato ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Recurrent Hernia ◽  
Perioperative Outcomes ◽  
Complication Rates ◽  
Conversion Rates ◽  
Quality Of Life Index ◽  
Group 2 ◽  
Gastrointestinal Quality Of Life ◽  
Group 1

Paraesophageal hernia repair (PEHR) is burdened by high recurrence rates that frequently lead to redo PEHR. Revisional surgery, because of higher complexity, higher risk of injury, and the intrinsic risk of recurrence, has increased likelihood of higher complication rates and decreased quality of life (QOL) postoperatively. We aimed to compare perioperative outcomes and QOL after revisional and primary PEHR. A retrospective review of all patients who underwent PEHR for a recurrent hernia between January 2011 and July 2016 was completed. These were matched with a contemporary cohort of patients who underwent primary PEHR by age, gender, and BMI. Perioperative measures were compared. The patients were invited to complete the Gastrointestinal Quality of Life Index (GIQLI) to assess response to surgical intervention. There were 24 patients (group 1) who underwent revisional PEHR, and they were matched to 48 patients (group 2) who had a primary hernia repair. Thirteen patients in group 1 responded to the survey (54%), whereas 21 patients’ responses were received from group 2 (44%). Conversion rates, LOS, and mean Gastrointestinal Quality of Life Index scores were significantly different between the two groups. Reoperative procedures for paraesophageal and hiatal hernias are burdened by higher conversion rates and length of stay, with similar overall complication rates. Patients who are undergoing repair of a recurrent hernia should be preoperatively counseled, and should have realistic expectations of their GI QOL after surgery.

Gastrointestinal Quality of Life Index: Development, validation and application of a new instrument

1995 ◽  
Vol 82 (2) ◽  
pp. 216-222 ◽  
Author(s):  
E. Eypasch ◽  
J. I. Williams ◽  
S. Wood-Dauphinee ◽  
B. M. Ure ◽  
C. Schmulling ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Index ◽  
New Instrument ◽  
Index Development ◽  
Quality Of Life Index ◽  
Gastrointestinal Quality Of Life

Response shift effect on gastrointestinal quality of life index after laparoscopic cholecystectomy

2010 ◽  
Vol 20 (3) ◽  
pp. 335-341 ◽  
Author(s):  
Hon-Yi Shi ◽  
King-Teh Lee ◽  
Hao-Hsien Lee ◽  
Yih-Huei Uen ◽  
Chong-Chi Chiu
Keyword(s):  
Quality Of Life ◽  
Laparoscopic Cholecystectomy ◽  
Response Shift ◽  
Life Index ◽  
Quality Of Life Index ◽  
Shift Effect ◽  
Gastrointestinal Quality Of Life

Validation of the gastrointestinal quality of life index for patients with potentially operable periampullary carcinoma

2000 ◽  
Vol 87 (1) ◽  
pp. 110-115 ◽  
Author(s):  
E. J. M. Nieveen van Dijkum ◽  
C. B. Terwee ◽  
P. Oosterveld ◽  
J. H. P. van der Meulen ◽  
D. J. Gouma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Periampullary Carcinoma ◽  
Life Index ◽  
Quality Of Life Index ◽  
Gastrointestinal Quality Of Life

scholarly journals The effect of group-based education on gastrointestinal symptoms and quality of life in patients with celiac disease: randomized controlled clinical trial

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Zahra Akbari Namvar ◽  
Reza Mahdavi ◽  
Masood Shirmohammadi ◽  
Zeinab Nikniaz
Keyword(s):  
Quality Of Life ◽  
Celiac Disease ◽  
Gastrointestinal Symptoms ◽  
Control Group ◽  
Post Intervention ◽  
Sf 36 ◽  
Gi Symptoms ◽  
Significant Difference ◽  
The Mean

Abstract Background In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD). Method In the present study, 130 patients with CD who were on a GFD for at least 3 months, randomly assigned to receive group-based education (n = 66) or routine education in the celiac clinic (n = 64) for 3 months. We assessed gastrointestinal symptoms and quality of life using the gastrointestinal symptom rating scale (GSRS) questionnaire and SF-36 questionnaire at baseline and 3 months after interventions. Results The mean age of the participants was 37.57 ± 9.59 years. There were no significant differences between the two groups regarding the baseline values. Results showed that the mean score of total GSRS score in the intervention group was significantly lower compared with the control group 3 months post-intervention (p = 0.04). Also, there was a significant difference in the mean score of SF-36 between the two groups 3 months post-intervention (p = 0.02). Conclusion Results showed that group-based education was an effective intervention in patients with celiac disease to improve gastrointestinal symptoms and quality of life. Trial registration IRCT code: IRCT20080904001197N21; registration date: 5/23/2019.

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