scholarly journals Effectiveness of Intravenous Immunoglobulin for Management of Pain in Patients with Postpolio Syndrome

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Min Cheol Chang ◽  
Jin-Sung Park ◽  
Jong-moon Hwang ◽  
Donghwi Park
Keyword(s):  
Muscle Strength ◽  
Intravenous Immunoglobulin ◽  
Prospective Observational Study ◽  
Treatment Results ◽  
High Quality ◽  
Postpolio Syndrome ◽  
Randomized Controlled ◽  
Before And After ◽  
And Function ◽  
Experience Pain

Objective. Many patients with postpolio syndrome (PPS) experience pain. In this study, we aimed to review previous studies to investigate the effectiveness of intravenous immunoglobulin (IVIG) for managing pain in patients with PPS. We performed a narrative review. Methods. In PubMed, we searched for the keywords ((Immunoglobulin OR IVIG) AND (poliomyelitis OR poliomyelitis syndrome)). We included articles in which IVIG was infused in patients with PPS and pain severity was measured before and after treatment. Results. In the results, five articles (4 randomized controlled trials and 1 prospective observational study) were included in this review. Four of the studies reported that IVIG had a positive pain-reducing effect in patients with PPS. In addition, 4 studies evaluated the outcomes related to muscle strength and function. Of these studies, 3 showed some improvement in measurements for muscle strength and function. Conclusion. In conclusion, IVIG might be one of the beneficial options for managing pain in PPS. Pain reduction might be responsible for the improvement of muscle strength or function. To confirm the benefits of IVIG in reducing pain, more high-quality studies are required.

scholarly journals Medium-chain triglycerides (8:0 and 10:0) are promising nutrients for sarcopenia: a randomized controlled trial

2019 ◽  
Vol 110 (3) ◽  
pp. 652-665 ◽  
Author(s):  
Sakiko Abe ◽  
Osamu Ezaki ◽  
Motohisa Suzuki
Keyword(s):  
Muscle Strength ◽  
Frail Elderly ◽  
Strength Function ◽  
Functional Independence ◽  
Medium Chain Triglycerides ◽  
Elderly Individuals ◽  
Medium Chain ◽  
Intention To Treat ◽  
Randomized Controlled ◽  
And Function

ABSTRACTBackgroundThe combined supplementation of medium-chain triglycerides (MCTs), l-leucine–rich amino acids, and cholecalciferol was previously shown to increase muscle strength and function in frail elderly individuals.ObjectiveWe examined whether treatment with MCTs alone is sufficient to increase muscle strength and function and activities of daily living (ADL) in such individuals.MethodsWe enrolled 64 elderly nursing home residents (85.5 ± 6.8 y) in a 3-mo randomized, controlled, single-blinded intervention trial. The participants were randomly assigned to 3 groups: the first group received supplemental l-leucine (1.2 g) and cholecalciferol (20 μg) enriched with 6 g/d of MCTs (LD + MCT group) as a positive control, the second group received 6 g/d of MCTs (MCT group) as a target, and the third group received 6 g/d of long-chain triglycerides (LCT group) as a negative control. Changes in muscle mass, strength, function, and ADL were monitored 4 times: at baseline, at 1.5 and 3 mo after initiation of the intervention (intervention), and 1.5 mo after termination of the intervention (washout).ResultsThe 64 participants randomly assigned to the 3 groups were included in an intention-to-treat analysis. Forty-eight participants completed the study and were included in a per-protocol analysis. At 3 mo, participants in the MCT group had a 48.1% increase in 10-s leg open and close test performance [intention-to-treat adjusted means: MCT 2.28 n/10 s (1.37, 3.19) compared with LCT −0.59 n/10 s (−1.52, 0.35), P < 0.05], a 27.8% increase in a 30-s repetitive saliva swallowing test [MCT 0.5 n/30 s (0.1, 1.0) compared with LCT −0.5 n/30 s (−0.9, 0.0), P < 0.05], and a 7.5% increase in Functional Independence Measure score, a questionnaire for assessing ADL [MCT 5.6 points (1.3, 9.9) compared with LCT −6.6 points (−11.3, −2.0), P < 0.05].ConclusionMCTs (6 g/d) could increase the muscle strength and function of frail elderly individuals and also improve their ADL. This trial was registered at the University Hospital Medical Information Network Clinical Trial Registry as UMIN000023302.

The Effect of Tourniquet Application on the Morphology and Function of Quadriceps in Patients Undergoing Total Knee Arthroplasty: A Study Protocol for a Single Blind Randomized Controlled Trial

2021 ◽  
Author(s):  
Ziyang Dong ◽  
Yang Li ◽  
Liyuan Tao ◽  
Hua Tian
Keyword(s):  
Total Knee Arthroplasty ◽  
Blood Loss ◽  
Knee Arthroplasty ◽  
Controlled Trial ◽  
Intraoperative Blood Loss ◽  
High Quality ◽  
Randomized Controlled ◽  
Total Knee ◽  
And Function ◽  
Single Blind

Abstract Background:Tourniquet is currently widely used in total knee arthroplasty to reduce intraoperative blood loss. Academic view of tourniquet application in TKA is now in dispute. Some scholars argue that tourniquet may cause quadriceps injury and bring extra side effects so they oppose the application of tourniquet. Others find that tourniquet application has no significant adverse impact on TKA patients. Regarding its advantages in reducing intraoperative blood loss, they advocate regular application of tourniquet in TKA. Quadriceps injury is considered the main cause of tourniquet side effects. There are now many high-quality trials about tourniquet application in TKA but few of them concentrate on quadriceps morphology and function.Methods:A prospective, single blind, randomized controlled trail will be adopted. The target sample is 130. Patients who meet the eligibility criteria will be randomly allocated to tourniquet group and non-tourniquet group. Primary outcomes are thickness, stiffness and function of quadriceps, which will be evaluated by ultrasound and rehabilitation tests. Secondary outcomes consist of circumference of thigh, VAS score, opioid consumption, knee function score, postoperative satisfaction score, operation time, intraoperative blood loss, perioperative blood loss, blood transfusion rate, D-Dimer, C-reactive protein, and complications. Discussion:This proposed study will contribute to improve evidence of tourniquet application in total knee arthroplasty. This will be a high-quality single blind randomized controlled trial with sufficient sample size and strict study design. It will investigate the effects of tourniquet application especially on the morphology and function of quadriceps in patients undergoing total knee arthroplasty and offer advice for tourniquet application in clinical practice.Trial registration:Chinese clinical trial registry, ChiCTR2000035097. Registered 31 July 2020, http://www.chictr.org.cn/showproj.aspx?proj=57093

scholarly journals Effectiveness of combined chain exercises on pain and function in patients with knee osteoarthritis

2016 ◽  
Vol 15 (2) ◽  
pp. 178-188 ◽  
Author(s):  
Oladapo Michael Olagbegi ◽  
Babatunde Olusola Adeleke Adegoke ◽  
Adesola C Odole
Keyword(s):  
Controlled Trial ◽  
Medical Science ◽  
Hip Osteoarthritis ◽  
Kinetic Chain ◽  
Knee Oa ◽  
Randomized Controlled ◽  
Dependent Variables ◽  
Before And After ◽  
And Function ◽  
Better Than

Objective: This randomized controlled trial was designed to investigate and compare the effectiveness of twelve-week open, closed and combined kinetic-chain exercises (OKCEs, CKCEs and CCEs) on pain and physical function (PF) in the management of knee osteoarthritis.Method: Ninety-six consecutive patients with knee OA were randomly assigned to one of OKCE, CKCE and CCE groups. Participants’ average daily pain (ADP), pain before and after walking (PBW and PAW), were evaluated using Visual Analogue Scale while PF was assessed using Ibadan Knee/Hip Osteoarthritis Outcome Measure.Results: Seventy-nine participants completed the study but data of another 4 participants who completed only 8-week treatment were included in data analysis (total=83; mean age = 61.10±13.75 years). The groups’ demographic and dependent variables were comparable at baseline but CCE group demonstrated significantly more reductions (p < 0.05) in ADP, PBW and PAW than OKCE and CKCE groups at weeks 4, 8 and 12 of the study. However, there were significant within group improvements (p < 0.05) in all four variables for the three groups. Conclusion: CCEs are better than OKCEs and CKCEs for pain reduction in though all three exercise regimens are singly effective. CCEs are recommended for improving treatment outcome for pain in patients with knee osteoarthritis.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.178-188

EFEITOS DO DEEP RUNNING SOBRE A AMPLITUDE DE MOVIMENTO E A CAPACIDADE FUNCIONAL DOS MEMBROS SUPERIORES DE MULHERES MASTECTOMIZADAS: RELATO DE CASOS

2019 ◽  
pp. 121-131
Keyword(s):  
Range Of Motion ◽  
Upper Limb ◽  
Functional Capacity ◽  
External Rotation ◽  
Treatment Protocol ◽  
Range Of Movement ◽  
Flexion Extension ◽  
Before And After ◽  
In The Beginning ◽  
And Function

Introduction: Breast cancer is the most common type of cancer among women in Brazil and in the worl. The surgical treatment procedure may cause severe morbidity in the upper limb homolateral to surgery, including the reduction of the range of motion, with consequent impairment of function. A physiotherapeutic approach has an important role in the recover range of motion and the functionality of these women, guaranteeing the occupational, domestestic, familiar and conjugated activities, and, in this way, also improving the quality of life. Objectives: To analyse chances in the shoulder's range of motion and the functional capacity of the upper limbs, promoted by the deep running procedure in women with late postoperative mastectomy. Methods: All the patients were submitted to an evaluation in the beginning and end of the treatment, including: goniometry of flexion, extension, abduction, adduction, internal and external rotation of the shoulder joint; and function capacity analysis in activities that involve the upper members by DASH questionnaire. The treatment protocol includes twelve sessions of deep running, realized twice a week, in deep pool, for 20-minute during six weeks. Results: Were submitted to treatment a total of 4 patients. Despite the improvement in the numerical values, statistically significant differences were not found on the range of movements and in the functional capacity of upper members before and after the deep running sessions in post-mastectomy women. Conclusion: Deep running had effects on the numerical values of range of movement and upper limb functionality in women in the late postoperative period of the mastectomy procedure, but without statistically significant differences.

EVALUATION OF THE EFFECTIVENESS OF NECK SHOULDER PAIN TREAMENT BY ACUPUNCTURE, MASSAGE AND TRADITIONAL MEDICINE REMEDY

2013 ◽  
pp. 110-117
Author(s):  
Thi Tan Nguyen
Keyword(s):  
Traditional Medicine ◽  
Shoulder Pain ◽  
Research Methodology ◽  
Pain Treatment ◽  
Central Hospital ◽  
Treatment Results ◽  
Good Account ◽  
Before And After ◽  
The City ◽  
Pain Patients

Objectives: To assess the effectiveness neck shoulder pain treatment by acupuncture, massage and traditional medicine remedy. Materials and Methods: 42 patients included in the inpatient and outpatient at the Department of Traditional Medicine, Hue Central Hospital and Traditional Medicine Hospital of Thua Thien Hue, was diagnosed as neck shoulder pain. Patients were treated with acupuncture, massage and medicine, according to the research methodology, assessing the results before and after treatment. Results: The age accounted for the highest proportion of 31-45 (42.49%), the second is between the ages of 46-60 (26.18%) and> 60 (26.18%). Incidence in the city (66.67%) than rural (33.33%) (p <0:05). Patients presented with neck shoulder pain (100%), together with the head pain, pain in the shoulder, arm numbness, movement restrictions tilted head bowed. Conclusion: good variety and accounted for 71.42% of which are quite good account of 14.28%, only 2.38% is poor. Results of good, high aged 31-45 (35.72%) and in patients with a course of treatment (66.66%). Key words: neck shoulder pain, acupuncture, massage, traditional medicine remedy.

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