scholarly journals Intelligent Monitoring of Care Status for COPD Patients Based on Deep Learning

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xiaoqun Chen ◽  
Yufen Yao
Keyword(s):  
Deep Learning ◽  
Lung Function ◽  
Partial Pressure ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Function Evaluation ◽  
Symptom Improvement ◽  
Blood Oxygen Saturation ◽  
Intelligent Monitoring ◽  
Copd Patients

To discuss the application method and effect of COPD patients in deep learning in intelligent monitoring, two groups were used under a reasonable selection of antibiotics specifically including reasonable and effective oxygen administration, atomization, sputum discharge treatment, psychotherapy, and rehabilitation training and treatment. Results were indicated, and there were significant differences between the lung function evaluation index and the two groups. Its intelligent monitoring mode was 97.5% and 80.0%, while the red blood cell ratio, arterial oxygen partial pressure (PaO2), pulse blood oxygen saturation (SpO2), arterial carbon dioxide partial pressure (PaCO2), and symptom improvement were better than artificial and were statistically significant ( P < 0.05 ). Therefore, the training of the anti-inspiratory muscle can effectively improve the lung function and dyspnea symptoms of COPD patients at the stable stage, thus greatly improving their respiratory function and ensuring the quality of life of patients, which is worthy of clinical application.

Variable Ventilation Improves Perioperative Lung Function in Patients Undergoing Abdominal Aortic Aneurysmectomy

2004 ◽  
Vol 100 (3) ◽  
pp. 608-616 ◽  
Author(s):  
Abdulaziz Boker ◽  
Craig J. Haberman ◽  
Linda Girling ◽  
Randy P. Guzman ◽  
George Louridas ◽  
...  
Keyword(s):  
Lung Function ◽  
Partial Pressure ◽  
Tidal Volume ◽  
Respiratory Rate ◽  
Control Mode ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Abdominal Aortic ◽  
Variable Ventilation ◽  
Abdominal Aortic Aneurysmectomy

Background Optimizing perioperative mechanical ventilation remains a significant clinical challenge. Experimental models indicate that "noisy" or variable ventilation (VV)--return of physiologic variability to respiratory rate and tidal volume--improves lung function compared with monotonous control mode ventilation (CV). VV was compared with CV in patients undergoing abdominal aortic aneurysmectomy, a patient group known to be at risk of deteriorating lung function perioperatively. Methods After baseline measurements under general anesthesia (CV with a tidal volume of 10 ml/kg and a respiratory rate of 10 breaths/min), patients were randomized to continue CV or switch to VV (computer control of the ventilator at the same minute ventilation but with 376 combinations of respiratory rate and tidal volume). Lung function was measured hourly for the next 6 h during surgery and recovery. Results Forty-one patients for aneurysmectomy were studied. The characteristics of the patients in the two groups were similar. Repeated-measures analysis of variance (group x time interaction) revealed greater arterial oxygen partial pressure (P = 0.011), lower arterial carbon dioxide partial pressure (P = 0.012), lower dead space ventilation (P = 0.011), increased compliance (P = 0.049), and lower mean peak inspiratory pressure (P = 0.013) with VV. Conclusions The VV mode of ventilation significantly improved lung function over CV in patients undergoing abdominal aortic aneurysmectomy.

An Evaluation of Transcutaneous Carbon Dioxide Partial Pressure Monitoring during Apnea Testing in Brain-dead Patients

2006 ◽  
Vol 104 (4) ◽  
pp. 701-707 ◽  
Author(s):  
Benoîit Vivien ◽  
Frédéric Marmion ◽  
Sabine Roche ◽  
Catherine Devilliers ◽  
Olivier Langeron ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Partial Pressure ◽  
Test Group ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Apnea Test ◽  
Transcutaneous Carbon Dioxide ◽  
Arterial Blood ◽  
The Mean ◽  
Brain Dead

Background Diagnosis of brain death usually requires an arterial carbon dioxide partial pressure (Paco2) of 60 mmHg during the apnea test, but the increase in Paco2 is unpredictable. The authors evaluated whether transcutaneous carbon dioxide partial pressure (Ptcco2) monitoring during apnea test can predict that a Paco2 of 60 mmHg has been reached. Methods The authors compared Ptcco2 measured with a transcutaneous ear sensor (V-Sign Sensor, Sentec Digital Monitoring System; SENTEC-AG, Therwil, Switzerland) and Paco2 obtained from arterial blood gas measurements in 32 clinically brain-dead patients. Results In the first 20 patients, the mean Paco2-Ptcco2 gradient was 0.7 +/- 3.6 mmHg at baseline and 8.7 +/- 7.1 mmHg after 20 min of apnea. Using receiver operating characteristic curve analysis (area under the curve: 0.983 +/- 0.013), the best threshold value of Ptcco2 to predict that a Paco2 of 60 mmHg had been reached was 60 mmHg (positive predictive value: 1.00 [0.93-1.00]). In the following 12 patients investigated with use of this Ptcco2 target value of 60 mmHg, the mean duration of the apnea test (11 +/- 4 vs. 20 +/- 0 min; P &lt; 0.001), hypercapnia (74.0 +/- 4.9 vs. 98.3 +/- 20.0 mmHg; P &lt; 0.001), acidosis (pH: 7.18 +/- 0.06 vs. 7.11 +/- 0.08; P &lt; 0.001), and decrease in arterial oxygen partial pressure (-47 +/- 44 vs. -95 +/- 89; P &lt; 0.05) at the end of the test were reduced as compared with the 20-min apnea test group. Conclusion During the apnea test in brain-dead patients, a Ptcco2 of 60 mmHg accurately predicts that a Paco2 of 60 mmHg has been reached. This may allow a reduction in the duration of the apnea test and consecutively limit occurrence of complications.

Undergraduate students' misconceptions about respiratory physiology.

1999 ◽  
Vol 277 (6) ◽  
pp. S127 ◽  
Author(s):  
J A Michael ◽  
D Richardson ◽  
A Rovick ◽  
H Modell ◽  
D Bruce ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Undergraduate Students ◽  
Liberal Arts ◽  
Minute Ventilation ◽  
Respiratory Physiology ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Physiological Variables ◽  
The Relationship

Approximately 700 undergraduates studying physiology at community colleges, a liberal arts college, and universities were surveyed to determine the prevalence of our misconceptions about respiratory phenomena. A misconception about the changes in breathing frequency and tidal volume (physiological variables whose changes can be directly sensed) that result in increased minute ventilation was found to be present in this population with comparable prevalence (approximately 60%) to that seen in a previous study. Three other misconceptions involving phenomena that cannot be experienced directly and therefore were most likely learned in some educational setting were found to be of varying prevalence. Nearly 90% of the students exhibited a misconception about the relationship between arterial oxygen partial pressure and hemoglobin saturation. Sixty-six percent of the students believed that increasing alveolar oxygen partial pressure leads to a decrease in alveolar carbon dioxide partial pressure. Nearly 33% of the population misunderstood the relationship between metabolism and ventilation. The possible origins of these respiratory misconceptions are discussed and suggestions for how to prevent and/or remediate them are proposed.

scholarly journals Electrocardiographic study on geriatric dogs undergoing general anesthesia with isoflurane

2008 ◽  
Vol 39 (2) ◽  
pp. 453-459
Author(s):  
Andreza Conti-Patara ◽  
Denise Tabacchi Fantoni ◽  
Silvia Renata Gaido Cortopassi
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Saturation ◽  
Partial Pressure ◽  
Normal Sinus Rhythm ◽  
Arterial Oxygen Saturation ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
T Wave ◽  
Arterial Blood ◽  
St Segment

The purpose of this study was to clarify the degree of influence of anesthetic agents commonly used during anesthesia on the heart conduction systems of geriatric dogs, with or without the presence of electrocardiographic changes in the pre-anesthetic electrocardiogram and also to determine the possible causes of ST-segment and T-wave changes during anesthesia, by monitoring ventilation and oxygenation. 36 geriatric dogs were evaluated. In addition to electrocardiographic evaluation, the pre-anesthetic study included serum levels of urea, creatinine, total protein, albumin and electrolytes. The pre-anesthetic medication consisted of acepromazine (0.05mg kg-1) in association with meperidine (3.0mg kg-1) by IM injection. Anesthesia was induced with propofol (3.0 to 5.0mg kg-1) by IV injection and maintained with isoflurane in 100% oxygen. During the anesthesia, the animals were monitored by continued computerized electrocardiogram. Systemic blood pressure, heart rate, respiratory rate, end-tidal carbon dioxide, partial pressure of carbon dioxide in arterial blood, arterial oxygen saturation, partial pressure of arterial oxygen and oxygen saturation of hemoglobin were closely monitored. During maintenance anesthesia, normal sinus rhythm was more common (78%). ST-segment and T-wave changes during the anesthetic procedure were quite common and were related to hypoventilation. The use of isoflurane did not result in arrhythmia, being therefore a good choice for this type of animal; Electrocardiographic findings of ST-segment and T-wave changes during the maintenance anesthesia were evident in animals with hypercapnia, a disorder that should be promptly corrected with assisted or controlled ventilation to prevent complicated arrhythmias.

scholarly journals Pulmonary ventilation reserve function is used to predict intraoperative ventilation function and postoperative outcome in patients with spinal orthopedic surgery

2021 ◽  
Vol 19 ◽  
pp. 205873922110321
Author(s):  
Mingshuai Yu ◽  
Ke Zhang ◽  
Lei Qi ◽  
Siyuan Liu
Keyword(s):  
Pulmonary Function ◽  
Partial Pressure ◽  
Orthopedic Surgery ◽  
Spontaneous Breathing ◽  
Pulmonary Ventilation ◽  
Postoperative Outcome ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Group A ◽  
Group B

Objective To investigate the effect of pulmonary ventilation reserve function on perioperative pulmonary function and postoperative outcome in patients undergoing spinal orthopedic surgery. Methods Ninety patients undergoing spinal orthopedic surgery in our hospital from June 2019 to December 2020 were divided into two groups according to the percentage of preoperative pulmonary reserve function index MVV in the predicted value. Arterial oxygen partial pressure, carbon dioxide partial pressure, oxygenation index (OI), airway plateau pressure (Pplat), and airway resistance (AR) of patients in each group were observed before the start of surgery (T0), at 1 h (T1) and 2 h (T2) after the start of surgery, and at the end of surgery (T3). After the end of surgery, the probability of patient transfer to ICU, time to resume spontaneous breathing, and time to extubation were recorded, and PaO2 and inflammatory factors interleukin-6, procalcitonin, and C-reactive protein of patients were followed up for 1 week. Results In both groups, PaO2 and OI decreased obviously while Pplat and AR increased significantly at T1, T2, and T3, but in Group A, Pplat and AR were markedly lower than those in Group B while PaO2 and OI were notably higher than those in Group B ( p < 0.05). Both time to resume spontaneous breathing and time to extubation in Group B were longer than those in Group A ( p < 0.05). The probability of entering ICU in Group B is higher than that in Group A. Both PaO2 and OI at day 3 after surgery in Group B were lower than those in Group A. While, there is no difference at T2. Conclusion For patients, both intraoperative pulmonary function and time to postoperative resuscitation can be predicted by measuring the preoperative MVV, and long-term prognosis will not be affected by the pulmonary function impairment.

scholarly journals Bispectral index in dogs with high intracranial pressure, anesthetized with propofol and submitted to two levels of FiO2

2011 ◽  
Vol 63 (6) ◽  
pp. 1359-1367
Author(s):  
P.C.F. Lopes ◽  
N. Nunes ◽  
L.G.G.G. Dias ◽  
G.B. Pereira Neto ◽  
R.M. Almeida ◽  
...  
Keyword(s):  
Intracranial Pressure ◽  
Partial Pressure ◽  
Bispectral Index ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Signal Quality Index ◽  
End Tidal ◽  
The Right ◽  
Inspired Oxygen ◽  
Rate Infusion

The effects of inspired oxygen fractions (FiO2) of 1 and 0.6 on bispectral index (BIS) in dogs with high intracranial pressure, submitted to a continuous rate infusion of propofol were evaluated. Eight dogs were anesthetized on two occasions, receiving, during controlled ventilation, an FiO2 = 1 (G100) or an FiO2 = 0.6 (G60). Propofol was used for induction (10mg.kg-1, IV), followed by a continuous rate infusion (0.6mg.kg-1.minute-1). After 20 minutes, a fiber-optic catheter was implanted on the surface of the right cerebral cortex to monitor the intracranial pressure, the baseline measurements of BIS values, signal quality index, suppression ratio number, electromyogram indicator, end-tidal carbon dioxide partial pressure, mean arterial pressure, intracranial pressure and cerebral perfusion pressure were taken. Then, the blood flow from the right jugular vein was interrupted in order to increase intracranial pressure and after 20 minutes additional recordings were performed at 15-minute intervals (T0, T15, T30, T45 and T60). The arterial oxygen partial pressure varied according to the changes in oxygen. For the other parameters, no significant differences were recorded. The BIS monitoring was not influenced by different FiO2.

Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats

2006 ◽  
Vol 290 (2) ◽  
pp. R405-R413 ◽  
Author(s):  
Leith C. R. Meyer ◽  
Andrea Fuller ◽  
Duncan Mitchell
Keyword(s):  
Oxygen Partial Pressure ◽  
Oxygen Saturation ◽  
Partial Pressure ◽  
Respiratory Depression ◽  
Carbon Dioxide Partial Pressure ◽  
Arterial Oxygen ◽  
Hemoglobin Oxygen Saturation ◽  
Arterial Oxygen Partial Pressure ◽  
Neurophysiological Studies ◽  
Serotonergic Drugs

Neurophysiological studies have shown that serotonergic ligands that bind to 5-HT1A, 5-HT7, and 5-HT4 serotonin receptors in brain stem have beneficial effects on respiratory neurons during opioid-induced respiratory depression. The effect of these ligands on respiratory function and pulmonary performance has not been studied. We therefore examined the effects of 8-hydroxy-2-(di- n-propylamino)tetralin (8-OH-DPAT), an agonist of 5-HT1A and 5-HT7 receptors, and zacopride, an agonist of 5-HT4 receptors, to establish whether these ligands would reverse opioid-induced respiratory depression and hypoxia without affecting the immobilizing properties of the opioid drug etorphine. When etorphine was used to sedate and immobilize goats, it significantly decreased respiratory rate ( P = 0.013), percent hemoglobin oxygen saturation ( P < 0.0001), and arterial oxygen partial pressure [PaO2; F(10,70) = 5.67, P < 0.05] and increased arterial carbon dioxide partial pressure [ F(10,70) = 3.87, P < 0.05] and alveolar-arterial oxygen partial pressure gradient [A-a gradients; F(10,70) = 8.23, P < 0.0001]. Zacopride and 8-OH-DPAT, coadministered with etorphine, both attenuated the effects of etorphine; respiration rates did not decrease, and percent hemoglobin oxygen saturation and PaO2 remained elevated. Zacopride decreased the hypercapnia, indicating an improvement in ventilation, whereas 8-OH-DPAT did not affect the hypercapnia and, therefore, did not improve ventilation. The main beneficial effect of 8-OH-DPAT was on the pulmonary circulation; it improved oxygen diffusion, indicated by the normal A-a gradients, presumably by improving ventilation perfusion ratios. Neither zacopride nor 8-OH-DPAT reversed etorphine-induced catatonic immobilization. We conclude that serotonergic drugs that act on 5-HT1A, 5-HT7, and 5-HT4 receptors reverse opioid-induced respiratory depression and hypoxia without reversing catatonic immobilization.

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