scholarly journals Precise Blood Glucose Sensing by Nitrogen-Doped Graphene Quantum Dots for Tight Control of Diabetes

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Seyyed Mojtaba Mousavi ◽  
Seyyed Alireza Hashemi ◽  
Ahmad Gholami ◽  
Sargol Mazraedoost ◽  
Wei-Hung Chiang ◽  
...  

Graphene quantum dots (GQD) are novel fluorescent carbon nanomaterials based on a graphite structure. Thanks to extraordinary properties such as high surface area and enhanced prevalent optical properties, they have received more interest for special applications. Glucose sensing is a critical factor for the diagnosis, and treatment of diabetes plays an important role and could contribute to the monitoring of diabetes and other related parameters, which has been effectively underscoring the health society. Detecting glucose has been cultivated through different systems, for example, electrochemical or optical techniques. Novel transducers made with GQD that fluorescent coordinate methods have considered the improvement of cutting-edge glucose sensors with prevalent affectability and accommodation. Currently, detection of glucose by nitrogen-doped GQD frameworks concerning the determined objectives has been considerably considered. Here, we explored the properties of fluorescent nitrogen-doped GQD as an excellent and effective index that significantly could promote nitrogen-doped GQDs and make them an appropriate candidate for detecting glucose.

NANO ◽  
2018 ◽  
Vol 13 (04) ◽  
pp. 1850041 ◽  
Author(s):  
Jing Wang ◽  
Lan Wang ◽  
Shubin Yang

A new type of vanadium nitride quantum dots anchored homogeneously onto nitrogen-doped graphene (VNQD-NG) is fabricated as nonprecious metal-based electrocatalysts for ORR via a combined hydrothermal and ammonia annealing process. The unique structural features of VNQD-NG including plentiful VN quantum dots with the sizes of 3–6[Formula: see text]nm, high surface area and multi-level pores afford considerable structural edges and defects as active sites, maximizing the exposed active sites and providing sufficient electron transport pathways for ORR. Hence, the optimized VNQD-NG exhibits high electrocatalytic activity, long durability and high selectivity for ORR, better than commercially available Pt-C.


2021 ◽  
Vol 623 ◽  
pp. 119077
Author(s):  
Rumwald Leo G. Lecaros ◽  
Reincess E. Valbuena ◽  
Lemmuel L. Tayo ◽  
Wei-Song Hung ◽  
Chien-Chieh Hu ◽  
...  

2021 ◽  
Author(s):  
Hemalatha Kuzhandaivel ◽  
Sornalatha Manickam ◽  
Suresh Kannan Balasingam ◽  
Manik Clinton Franklin ◽  
Hee-Je Kim ◽  
...  

Sulfur and nitrogen-doped graphene quantum dots/polyaniline nanocomposites were synthesized and their electrochemical charge storage properties were tested for supercapacitor applications.


ACS Omega ◽  
2021 ◽  
Vol 6 (3) ◽  
pp. 2167-2176
Author(s):  
Rania Adel ◽  
Shaker Ebrahim ◽  
Azza Shokry ◽  
Moataz Soliman ◽  
Marwa Khalil

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 140
Author(s):  
Madison Frieler ◽  
Christine Pho ◽  
Bong Han Lee ◽  
Hana Dobrovolny ◽  
Giridhar R. Akkaraju ◽  
...  

With 18 million new cases diagnosed each year worldwide, cancer strongly impacts both science and society. Current models of cancer cell growth and therapeutic efficacy in vitro are time-dependent and often do not consider the Emax value (the maximum reduction in the growth rate), leading to inconsistencies in the obtained IC50 (concentration of the drug at half maximum effect). In this work, we introduce a new dual experimental/modeling approach to model HeLa and MCF-7 cancer cell growth and assess the efficacy of doxorubicin chemotherapeutics, whether alone or delivered by novel nitrogen-doped graphene quantum dots (N-GQDs). These biocompatible/biodegradable nanoparticles were used for the first time in this work for the delivery and fluorescence tracking of doxorubicin, ultimately decreasing its IC50 by over 1.5 and allowing for the use of up to 10 times lower doses of the drug to achieve the same therapeutic effect. Based on the experimental in vitro studies with nanomaterial-delivered chemotherapy, we also developed a method of cancer cell growth modeling that (1) includes an Emax value, which is often not characterized, and (2), most importantly, is measurement time-independent. This will allow for the more consistent assessment of the efficiency of anti-cancer drugs and nanomaterial-delivered formulations, as well as efficacy improvements of nanomaterial delivery.


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