scholarly journals The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Jiajie Tu ◽  
Huan Yang ◽  
Lei Jiang ◽  
Yu Chen ◽  
Yu Chen ◽  
...  
Keyword(s):  
Reproductive System ◽  
Noncoding Rna ◽  
Noncoding Rnas ◽  
Future Research ◽  
Female Reproductive System ◽  
Research Directions ◽  
New Ideas ◽  
Future Research Directions

The pathogenesis of ovarian and endometrial cancers is closely associated with estrogen-related pathways. These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. This review systematically summarizes the role of ncRNAs in estrogen-dependent tumors and common patterns of regulatory mechanisms to explore their future research directions in tumor diagnosis, treatment, and prognosis. This may provide new ideas for the potential application of ncRNAs in estrogen-dependent female reproductive system tumors.

scholarly journals Passion in Sport: On the Quality of the Coach–Athlete Relationship

2008 ◽  
Vol 30 (5) ◽  
pp. 541-560 ◽  
Author(s):  
Marc-André K. Lafrenière ◽  
Sophia Jowett ◽  
Robert J. Vallerand ◽  
Eric G. Donahue ◽  
Ross Lorimer
Keyword(s):  
Positive Emotions ◽  
Well Being ◽  
Future Research ◽  
Subjective Well Being ◽  
High Quality ◽  
Research Directions ◽  
Dualistic Model Of Passion ◽  
Future Research Directions

Vallerand et al. (2003) developed a dualistic model of passion, wherein two types of passion are proposed: harmonious (HP) and obsessive (OP) passion that predict adaptive and less adaptive interpersonal outcomes, respectively. In the present research, we were interested in understanding the role of passion in the quality of coach–athlete relationships. Results of Study 1, conducted with athletes (N = 157), revealed that HP positively predicts a high-quality coach–athlete relationship, whereas OP was largely unrelated to such relationships. Study 2 was conducted with coaches (N = 106) and showed that only HP positively predicted the quality of the coach–athlete relationship. Furthermore, these effects were fully mediated by positive emotions. Finally, the quality of the coach–athlete relationship positively predicted coaches’ subjective well-being. Future research directions are discussed in light of the dualistic model of passion.

Interpersonal Psychotherapy for the Treatment of Eating Disorders

2010 ◽  
pp. 347-372 ◽  
Author(s):  
Marian Tanofsky-Kraff ◽  
Denise E. Wilfley
Keyword(s):  
Anorexia Nervosa ◽  
Clinical Care ◽  
Interpersonal Psychotherapy ◽  
Future Research ◽  
Cognitive Behavior ◽  
Research Directions ◽  
Routine Clinical Care ◽  
Interpersonal Factors ◽  
Future Research Directions

Interpersonal psychotherapy (IPT) is a focused, time-limited treatment that targets interpersonal problem(s) associated with the onset and/or maintenance of EDs. IPT is supported by substantial empirical evidence documenting the role of interpersonal factors in the onset and maintenance of EDs. IPT is a viable alternative to cognitive behavior therapy for the treatment of bulimia nervosa and binge eating disorder. The effectiveness of IPT for the treatment of anorexia nervosa requires further investigation. The utility of IPT for the prevention of obesity is currently being explored. Future research directions include enhancing the delivery of IPT for EDs, increasing the availability of IPT in routine clinical care settings, exploring IPT adolescent and parent–child adaptations, and developing IPT for the prevention of eating and weight-related problems that may promote full-syndrome EDs or obesity.

scholarly journals Computational Techniques for Eye Movements Analysis towards Supporting Early Diagnosis of Alzheimer’s Disease: A Review

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Jessica Beltrán ◽  
Mireya S. García-Vázquez ◽  
Jenny Benois-Pineau ◽  
Luis Miguel Gutierrez-Robledo ◽  
Jean-François Dartigues
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Eye Movements ◽  
Early Diagnosis ◽  
Future Research ◽  
Computational Techniques ◽  
Research Directions ◽  
Future Research Directions ◽  
Tools And Techniques

An opportune early diagnosis of Alzheimer’s disease (AD) would help to overcome symptoms and improve the quality of life for AD patients. Research studies have identified early manifestations of AD that occur years before the diagnosis. For instance, eye movements of people with AD in different tasks differ from eye movements of control subjects. In this review, we present a summary and evolution of research approaches that use eye tracking technology and computational analysis to measure and compare eye movements under different tasks and experiments. Furthermore, this review is targeted to the feasibility of pioneer work on developing computational tools and techniques to analyze eye movements under naturalistic scenarios. We describe the progress in technology that can enhance the analysis of eye movements everywhere while subjects perform their daily activities and give future research directions to develop tools to support early AD diagnosis through analysis of eye movements.

The Effectiveness of Family-Supportive Supervisors: The Moderating Role of Employees’ Collectivistic Self-Construal

2020 ◽  
Vol 51 (6) ◽  
pp. 442-455
Author(s):  
Peng Wang ◽  
Zhengxue Luo ◽  
Zhen Wang
Keyword(s):  
Self Determination Theory ◽  
Employee Perceptions ◽  
Future Research ◽  
Research Directions ◽  
Self Construal ◽  
Member Exchange ◽  
Future Research Directions ◽  
Work Family ◽  
Work Family Enrichment

Built upon conservation of resource theory and self-determination theory, this study explores boundary conditions under which family-supportive supervisors (FSSs) influence employee-perceived leader–member exchange (LMX) and work–family enrichment (WFE). Findings from this research reveal that FSSs positively relate to employee perceptions of LMX and WFE. Employees’ collectivistic self-construals moderate the effect of FSSs on LMX but not on WFE. Implications and future research directions are discussed.

Cardiovascular Comorbidities of Psoriasis and Psoriatic Arthritis: A Report from the GRAPPA 2012 Annual Meeting

2013 ◽  
Vol 40 (8) ◽  
pp. 1434-1437 ◽  
Author(s):  
April W. Armstrong ◽  
Joel M. Gelfand ◽  
Wolf-Henning Boehncke ◽  
Ehrin J. Armstrong
Keyword(s):  
Psoriatic Arthritis ◽  
Annual Meeting ◽  
Tumor Necrosis ◽  
Panel Discussion ◽  
Future Research ◽  
Research Directions ◽  
Cardiovascular Comorbidities ◽  
Future Research Directions ◽  
Necrosis Factor

At the 2012 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) in Stockholm, Sweden, several GRAPPA members led a panel discussion on cardiovascular (CV) comorbidities of psoriasis and psoriatic arthritis (PsA). The panelists discussed the role of insulin resistance in the pathophysiology of psoriasis, the possible effect of tumor necrosis factor inhibitors on CV comorbidities, and the effect of 12/23 monoclonal antibodies on CV outcomes. The panelists also addressed how lessons from CV comorbidity research could be applied to other areas of comorbidity research in psoriasis and PsA and identified future research directions in this area.

scholarly journals Emerging role of a novel small non-coding regulatory RNA: tRNA-derived small RNA

ExRNA ◽  
2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Fangfang Jin ◽  
Zhigang Guo
Keyword(s):  
Small Rna ◽  
Current Knowledge ◽  
Future Research ◽  
Regulatory Rna ◽  
Biological Functions ◽  
Research Directions ◽  
Non Coding Rna ◽  
Future Research Directions ◽  
Non Coding Rnas

Abstract The discovery of small non-coding RNAs, such as miRNA and piRNA, has dramatically changed our understanding of the role RNA plays in organisms. Recent studies show that a novel small non-coding RNA generated from cleavage of tRNA or pre-tRNA, called tRNA-derived small RNA (tsRNA), serves as a new regulator of gene expression. tsRNA has been determined participate in regulating some specific physiological and pathological processes. Although knowledge regarding the biological roles of miRNA and piRNA is expanding, whether tsRNAs play similar roles remains poorly understood. Here, we review the current knowledge regarding the mechanisms of action and biological functions of tsRNAs in intracellular, extracellular and intergenerational inheritance, and highlight the potential application of tsRNAs in human diseases, and present the current problems and future research directions.

Value Co-Creation in Cloud Services

2013 ◽  
pp. 74-91 ◽  
Author(s):  
Ammar Rashid ◽  
William Yu Chung Wang ◽  
Felix B. Tan
Keyword(s):  
Service Providers ◽  
Practical Experience ◽  
Cloud Services ◽  
Future Research ◽  
Research Directions ◽  
Technical Aspects ◽  
Creation Process ◽  
Managerial Implications ◽  
Future Research Directions

In recent years, there has been considerable interest in cloud services in academic literature. Most research in this area has focused on the technical aspects of designing and implementing cloud services, with few studies focusing on understanding the value of cloud services and the processes by which consumer and service providers engage each other to co-create these services. This chapter explains the co-creation processes, and, the role of consumer in the value co-creation process of cloud services. It incorporates extant marketing and information systems literature, industry reports, and practical experience reflections to highlight the significance of cloud services. The drivers of co-creation are explored with the description of co-creation processes and the underlying factors involved in value co-creation of cloud services. The chapter concludes by outlining the opportunities associated with the development of cloud services, noting future research directions and discussing academic and managerial implications.

The Role of Human Resources in Hotels in China

2015 ◽  
pp. 164-181
Author(s):  
Jenny Chen
Keyword(s):  
Human Resources ◽  
Hotel Industry ◽  
Future Research ◽  
Great Contribution ◽  
Research Directions ◽  
Good Person ◽  
Future Research Directions ◽  
Points Of View

There was a famous saying from the celebrated hotelier, “king of hoteliers and hotelier to kings,” Mr. Cesar Ritz, that a good person is priceless (Leng, 2013). Human resources has always played a very important role in hotels. This is because the hotel industry is a labor-intensive industry that requires great contribution and support from human resources to identify and recruit the required staff, train and manage the manpower to fill the various jobs, and retain and develop the talented employees for greater responsibilities or higher positions. This chapter displays the changes of the role of human resources in hotels in China and its significant impact of the changes to the industry. In addition, this chapter also provides its unique points of view in the part of Solutions and Recommendations and in the part of Future Research Directions.

Business Models and Organizational Processes Changes

2011 ◽  
pp. 192-205
Author(s):  
Helena Halas ◽  
Tomaž Klobucar
Keyword(s):  
Pervasive Computing ◽  
Business Models ◽  
Business Processes ◽  
Future Research ◽  
Organizational Processes ◽  
Research Directions ◽  
Main Stress ◽  
Future Research Directions ◽  
Future Business

This chapter explores the influence of pervasive computing on companies and their businesses, with the main stress on business models. The role of business models for companies is presented. Introduction to pervasive computing and a survey of existing e-business models classifications are used as a base for our research. The main characteristics of today’s business models are discussed and a method for evaluating business models characteristics is proposed. We concentrate on characteristics of pervasive computing and their influence on companies’ business processes and business models. The present and future business characteristics and business models are briefly compared, and future research directions on pervasive computing and business models are presented.

Science for All through Reflective Interactions

2012 ◽  
pp. 102-118 ◽  
Author(s):  
Jennifer J. Neakrase ◽  
H. Prentice Baptiste ◽  
Ashley N. Ryan ◽  
Elsa Q. Villa
Keyword(s):  
Science Classroom ◽  
Future Research ◽  
Online Environment ◽  
Science Content ◽  
Science Concept ◽  
Research Directions ◽  
Online Interactions ◽  
Future Research Directions ◽  
The Individual

One of the goals of science education is to ensure that the discipline of science is accessible to all individuals. By many organizations this has been termed “Science for All,” and those who promote this idea also advocate the connection to science literacy. Teaching science in the online environment has been one way to offer science content to many different individuals, who do not necessarily need to be in the same location. Discourse in the science classroom is framed under situated cognition theory, whereby interactions between individuals are part of the normal culture of the classroom. For science knowledge to be adequately constructed by a student these interactions must be meaningful ones. This is especially important in an online science course where typically learning occurs through interactions between the students and the instructor, the students with one another, and within the individual themselves. As part of these online interactions, good reflective practice includes the different forms of feedback and the quality of this feedback. However, even with quality reflective interactions, there are barriers to science concept construction in an online environment. These barriers are discussed, and future research directions are suggested based on this review.

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