scholarly journals In Vitro Assessment of Artificial Aging on the Antifungal Activity of PMMA Denture Base Material Modified with ZrO2 Nanoparticles

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Shorouq Khalid Hamid ◽  
Lujain Ali Alghamdi ◽  
Faris A. Alshahrani ◽  
Soban Q. Khan ◽  
Asif Matin ◽  
...  

The antifungal effect of zirconium dioxide nanoparticles (ZrO2NPs) incorporated into denture base material has been inadequately investigated; additionally, to the authors’ knowledge, no studies have assessed the influence of artificial aging on the antifungal activity of these particles. Methodology. Heat-polymerized acrylic resin disks were fabricated and divided into four groups (0%, 1%, 2.5%, and 5% ZrO2NPs by weight). Antifungal activity was assessed using the direct culture and disk diffusion methods. Surface roughness and contact angles were measured using a profilometer and a goniometer, respectively. The artificial aging procedure was performed by repeating all tests at 7, 14, and 30 days following 2 rounds of thermocycling. Data were analyzed using ANOVA and Tukey’s post-hoc test ( p < 0.05 ). Results. The addition of ZrO2NPs significantly decreased the adhesion of Candida albicans with and without artificial aging procedures ( p < 0.001 ), while the disk diffusion methods did not reveal inhibition zones. ZrO2NP-modified specimens displayed significantly higher surface roughness compared to specimens in the control group ( p < 0.05 ) and showed the same behaviors with artificial aging procedures. The contact angle was significantly decreased in all modified groups in comparison to the control group ( p < 0.05 ). Conclusion. The addition of ZrO2NPs to polymethylmethacrylate denture base material reduced the adhesion of Candida albicans with a long-term antifungal effect. With the addition of ZrO2NPs, contact angles were decreased and surface roughness was increased; 1% was the most appropriate concentration. Clinical significance. The addition of ZrO2NPs to denture base material confers a long-term antifungal effect and could be used as a possible method for preventing and treating denture stomatitis.

Author(s):  
Kubra Degirmenci ◽  
Mustafa Hayati Atala ◽  
Canan Sabak

Avoiding biofilm formation on dentures is associated with maintaining the surface properties of acrylic-based dentures. The aim of the study is to investigate the effects of two different cleaning agents (Corega and Klorhex 0.2% chlorhexidine gluconate) on surface roughness of the denture regarding efficacy of curing procedures. A total of sixty disc-shaped specimens were prepared with two different methods as long and short curing processes. The specimens were divided into subgroups according to the immersion solutions (distilled water, Corega tablet group and Klorhex 0.2% chlorhexidine gluconate group) (n=10). The samples were kept in a solution for 8 hours per day during a month. The average Ra1 (before exposure to the cleanser agent) and Ra2 (after exposure to the cleanser agent) of each sample was measured. A two-way ANOVA and post hoc Tukey test was used for statistical analysis. The solutions significantly increased the Ra values in both acrylic groups (p<0.001). While the effect of the distilled water group was significantly lower than Corega and Klorhex in the long-term curing group (p<0.05), no significant difference was found in the short-term curing group (p>0.05). The long-term curing time is highly effective in decreasing the surface roughness of the acrylic base material.


2020 ◽  
Vol 5 (1) ◽  
pp. 36-43
Author(s):  
Gladis Aprilla Rizki ◽  
Sri Wahyuningsih Rais ◽  
Martha Mozartha

Alcoholic beverages can be consumed in any group age, and it may be consumed by an individual using denture. Fluid absorption by heat-cured acrylic resin as a material of a denture base was able to cause an increase in its surface roughness. Absorption of an organic solvent such as the ethanol in an alcoholic beverage(s) could even increase the effect. This study aimed to evaluate the effect of alcohol beverages on surface roughness of heat-cured acrylic resin denture base. Samples (n=24) were prepared from heat-cured acrylic resin (25x25x5 mm). They were divided into 4 groups and the pre-test surface roughness was measured. Samples of each group were immersed for 10 minutes into the solution (distilled water as the control group, beer, wine, and whiskey as the test groups). After stored in artificial saliva for 23 hours, the samples were immersed into the solution, completing a period of 24 hours. This procedure was performed for 7 consecutive days and the post-test surface roughness was measured. Data were statistically analyzed using the Kruskal-Walis test. There was a significant difference in surface roughness measurement before and after the immersion (p<0.05). Whiskey was most affecting the surface roughness of heat-cured acrylic resin denture base. Alcoholic beverages could increase the surface roughness of heat cure acrylic resin denture base. Keywords: Alcoholic beverages; Heat-cured acrylic denture base; Surface roughness


2018 ◽  
Vol 2 (2) ◽  
pp. 120-131
Author(s):  
Fahd Ikram

Despite the development of many denture base material like chrome-cobalt, fluid and plastic material but the heat cure polymethylmethacrylate considered as the most widely used denture base material. The aims of this study to evaluate and compare the impact strength and surface roughness of heat cured denture base resin after immersing incoca-cola drink for two and four weeks. Methods: A total number of 40 samples were prepared, 30 samples for impact strength test and 10 samples for surface roughness test. The samples were divided into three group; A (control), B (2 weeks immersed in coca cola drink), and C (4 weeks immersed in coca cola drink). Result: Data analyzed by using SPSS software with ANOVA test indicated a non significant differences between the different tested groups, however the samples that were immersed in coca cola drink for 4 weeks revealed non dramatic increase in surface roughness, while the samples that were immersed for 2 weeks showed a non dramatic decrease in the impact strength. Conclusions: The coca cola drink non significantly caused dropping in the tested properties in comparison to the control group.


2021 ◽  
Vol 1 (Volume 1 No 2) ◽  
pp. 165-174
Author(s):  
Rheni Safira Isnaeni ◽  
Zwista Yulia Dewi ◽  
Muhammad Hamzah Rahmatullah

Polyamide resin is widely used in dentistry as a denture base material. Cinnamon burmanii has been proven to have antibacterial and antifungal substances. Therefore, it is the potential to be used as a nature denture cleanser. This study aimed to examine the effect of soaking 50% cinnamon extract solution on the surface roughness of polyamide resin. This study used 16 polyamide resin samples soaked in 50% cinnamon extract solution and 16 samples soaked in distilled water as the control group. It examined the surface roughness before and after immersion for four days and seven days. Data were analyzed using paired T-test and independent T-test. The results showed a significant difference in the surface roughness of polyamide resin before and after immersion in cinnamon solution for four days and seven days. The surface roughness change is due to the polyphenol's reaction on the polyamide resin surface, which has destroyed the polymer chain of polyamide resin.


Author(s):  
Amal Nawasrah ◽  
Mohammed Gad ◽  
Mai El Zayat

Statement of problem: Henna has been added to polymethylmethacrylate (PMMA) as a new type of antifungal agent; however, its effect on the latter&rsquo;s physical properties has not been investigated. Purpose: This study aimed to evaluate the effect of the addition of various henna concentrations on the surface roughness and hardness of PMMA denture base material. Materials and Methods: A total of 99 specimens of rectangular-shaped (10&times;20&times;3 mm3) acrylic specimens were prepared from heat-cured acrylic resin. Specimens were divided into one control group without the addition of henna and five test groups, which were prepared by adding Yamani henna powder to acrylic powder at concentrations of 1wt%, 2.5wt%, 5wt%, 7.5wt%, and 10wt%. The polymer was added to the monomer before being mixed, packed, and processed using the conventional water bath method. After processing, specimens were finished and polished, then kept in distilled water for 48+2 h. A profilometer and Vickers hardness tester were used to measure surface roughness and hardness respectively. Statistical data analysis was conducted via SPSS version 20.0 (IBM, USA). Results: The addition of henna at varying concentrations significantly increased surface roughness values (P &le; 0.01) while decreasing hardness (P &le; 0.0001). The most favorable addition value was 1% henna between all henna groups. Conclusion: The addition of henna to the acrylic resin may negatively affect the surface properties of PMMA acrylic denture base.


2021 ◽  
Vol 17 (1) ◽  
pp. 22-26
Author(s):  
Kadek Ayu Wirayuni ◽  
◽  
I Made Hendri Dwi Saputra ◽  

Introduction: The denture base is the part of the removable denture that is supported by good adaptation to the underlying oral tissue. Most of the denture bases are made of acrylic or polymethyl methacrylate resin, better known as PMMA. However, the acrylic resin also has disadvantages such as easily broken and absorbs liquids both water and chemicals. The chemical absorption like alcohol, ethanol, and some drinks that contain acidic materials will chemically be induced with acrylic resin and settle in the pores of the acrylic resin. The chemical damage or defect creates roughness on the surface of the acrylic resin which can cause cracking or crazing and a decrease in surface strength and hardness. Materials and Methods: The method used in this research was a laboratory experimental design with a post-test-only control group using 12 samples consisting of 2 different types of samples by measuring the surface roughness of the acrylic resin after immersing the sample with a predetermined time. Results and Discussions: One-way ANOVA test results showed a significant difference in surface roughness after the samples immersion with a value of p = 0.006 (p <0.05). Conclusions: Based on this research, can be concluded that there is an increase in the surface roughness of the heated polymerized acrylic resin for 3 hours and 4 hours of immersion. The longer the heated polymerized acrylic resin is soaked in arak hence the level of surface roughness increases.


2014 ◽  
Vol 43 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Cíntia Lima Gouveia ◽  
Isabelle Cristine Melo Freire ◽  
Maria Luísa de Alencar e Silva Leite ◽  
Rebeca Dantas Alves Figueiredo ◽  
Leopoldina de Fátima Dantas de Almeida ◽  
...  

Introduction: The effectiveness of antimicrobial solutions employed in dental prosthesis decontamination is still uncertain. Aim: To evaluate the antifungal activity of cleaners used in the decontamination of dental prostheses on the growth of Candida albicans. Material and method: The evaluated products were: Corega Tabs(r) (S1), Sodium Hypochlorite 1% (S2), Sodium Bicarbonate 1% (S3), Hydrogen Peroxide 1% (S4), Chlorhexidine Digluconate 0.12% - Periogard (r) (S5), Mouthrinse based on essential oils - Listerine(r) (S6), essential oil from Rosmarinus officinalis (rosemary) at concentrations of 1% (S7) and 2% (S8). The antifungal activity of the products was evaluated by agar diffusion technique and the determination of microbial death curve of samples of C. albicans (ATCC 90028) in concentration 1.5 × 106 CFU/mL. The tests were performed in triplicate and statistical analysis was made by ANOVA Two-Way and Tukey tests, with the confidence level of 95%. Result: The average of the zones of inhibition growth, in millimeters, obtained for the products were: 0.0 (S1), 44.7 (S2), 0.0 (S3), 21.6 (S4), 10.0 (S5), 6.1 (S6), 0.0 (S7) and 2.4 (S8). Considering the determination of microbial death curve, all products showed a statistical difference (p<0.01) from control (0.85% sodium chloride) and S3 groups. Fungal growth less than 2×104 CFU/mL and an accentuation of the microbial death curve were observed after 30 minutes, with exception for S3 and control groups. Conclusion: The studied compounds, with the exception of Sodium Bicarbonate, have antifungal effect against C. albicans, which contribute for dental prostheses hygiene.


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