scholarly journals Dynamic Stochastic Optimization of Emergent Blood Collection and Distribution from Supply Chain Perspective

Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Xiangyu Jin ◽  
Huajun Tang ◽  
Yuxin Huang
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Collection ◽  
Chain Model ◽  
Blood Supply Chain ◽  
Conduct Sensitivity Analysis ◽  
Managerial Implications ◽  
Dynamic Stochastic

In response to emergencies, it is critical to investigate how to deliver emergency supplies efficiently and securely to disaster-affected areas and people. There is no doubt that blood is deemed one of the vital relief supplies, and ensuring smooth blood delivery may substantially alleviate subsequent impacts caused by the disaster. Taking red blood cell products as the research object, this work proposes a four-echelon blood supply chain model. Specifically, it includes blood donors, blood donation houses, blood centres, and hospitals. Furthermore, numerical analysis is provided to test the feasibility of blood collection and distribution schemes and conduct sensitivity analysis to test the impacts of the relevant parameters (e.g., apheresis donation proportion of red blood cells (RBCs), distance between blood donors and blood facilities, and times of blood donation) on the scheme. This research provides some scientific and reasonable support for decision makers and managerial implications for emergency departments and contributes to the study of emergent blood supply chain.

scholarly journals Local Blood Supply Chain Optimization: A Case Study

2020 ◽  
Vol 18 (4) ◽  
Author(s):  
Reza Babazadeh ◽  
Ali Sabbaghnia ◽  
Fatemeh Shafipour
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Blood Donation ◽  
Programming Model ◽  
Human Life ◽  
Mixed Integer ◽  
Model Parameters ◽  
Supply Chain Optimization ◽  
Blood Supply Chain ◽  
Proposed Model

: Blood and its products play an undeniable role in human life. In recent years, although both academics and practitioners have investigated blood-related problems, further enhancement is still warranted. In this study, a mixed-integer linear programming model was proposed for local blood supply chain management. A supply network, including temporary and fixed blood donation facilities, blood banks, and blood processing centers, was designed regarding the deteriorating nature of blood. The proposed model was applied in a real case in Urmia, Iran. The numerical results and sensitivity analysis of the key model parameters ensured the applicability of the proposed model.

scholarly journals A cross-sectional study of prevalence, distribution, cause, and impact of blood product recalls in the United States

2020 ◽  
Vol 4 (8) ◽  
pp. 1780-1791
Author(s):  
Ibrahim Alqemlas ◽  
Sneha Shankar ◽  
Winode Handagama ◽  
P. Arthur Felse
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Blood Product ◽  
The United States ◽  
Blood Collection ◽  
Product Recalls ◽  
Blood Products ◽  
Blood Supply Chain ◽  
High Prevalence ◽  
Reduced Products

Abstract Defective blood products that are recalled because of safety or potency deviations can trigger adverse health events and constrict the nation’s blood supply chain. However, the underlying characteristics and impact of blood product recalls are not fully understood. In this study, we identified 4700 recall events, 7 reasons for recall, and 144 346 units affected by recalls. Using geospatial mapping of the newly defined county-level recall event density, we discovered hot spots with high prevalence and likelihood of blood product recall events. Distribution patterns and distribution distances of recalled blood products vary significantly between product types. Blood plasma is the most recalled product (87 980 units), and leukocyte-reduced products (34 230 units) are recalled in larger numbers than non-leukocyte-reduced products (8076 units). Donor-related reasons (92 382 units) and sterility deviations (22 408 units) are the major cause of blood product recalls. Monetary loss resulting from blood product recalls is estimated to be $17.9 million, and economic sensitivity tests show that donor-related reasons and sterility deviations contribute most to the overall monetary burden. A total of 2.8 million days was required to resolve recall events, and probabilistic survival time analysis shows that sterility deviations and contamination took longer to resolve because of their systemic effect on blood collection and processing. Our studies demonstrate that better donor screening procedures, rigorous sterility requirements, improved containment methods, and mitigation of recall events in high-prevalence regions will enable a more robust blood supply chain.

scholarly journals Stochastic Inventory Model for Minimizing Blood Shortage and Outdating in a Blood Supply Chain under Supply and Demand Uncertainty

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Han Shih ◽  
Suchithra Rajendran
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Demand Uncertainty ◽  
Supply And Demand ◽  
Chain Model ◽  
Supply Uncertainty ◽  
Demand And Supply ◽  
Blood Supply Chain ◽  
Supply Chain Model ◽  
Inventory Holding

Purpose. Blood, like fresh produce, is a perishable element, with platelets having a limited lifetime of five days and red blood cells lasting 42 days. To manage the blood supply chain more effectively under demand and supply uncertainty, it is of considerable importance to developing a practical blood supply chain model. This paper proposed an essential blood supply chain model under demand and supply uncertainty. Methods. This study focused on how to manage the blood supply chain under demand and supply uncertainty effectively. A stochastic mixed-integer linear programming (MILP) model for the blood supply chain is proposed. Furthermore, this study conducted a sensitivity analysis to examine the impacts of the coefficient of demand and supply variation and the cost parameters on the average total cost and the performance measures (units of shortage, outdated units, inventory holding units, and purchased units) for both the blood center and hospitals. Results. Based on the results, the hospitals and the blood center can choose the optimal ordering policy that works best for them. From the results, we observed that when the coefficient of demand and supply variation is increased, the expected supply chain cost increased with more outdating units, shortages units, and holding units due to the impacts of supply and demand fluctuation. Variation in the inventory holding and expiration costs has an insignificant effect on the total cost. Conclusions. The model developed in this paper can assist managers and pathologists at the blood donation centers and hospitals to determine the most efficient inventory policy with a minimum cost based on the uncertainty of blood supply and demand. The model also performs as a decision support system to help health care professionals manage and control blood inventory more effectively under blood supply and demand uncertainty, thus reducing shortage of blood and expired wastage of blood.

scholarly journals Strategies for blood collection and optimization of the blood supply chain during the COVID‐19 pandemic in Greece

2020 ◽  
Vol 15 (4) ◽  
pp. 386-392
Author(s):  
Constantina Politis ◽  
Clive Richardson ◽  
Helen Hassapopoulou‐Matamis ◽  
Lida Politi ◽  
Kyriaki Hatziagapiou ◽  
...  
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Blood Collection ◽  
Blood Supply Chain

scholarly journals Blood Donation Program in Malaysia: Government Initiatives towards Attracting Volunteer Blood Donors

2018 ◽  
Vol 7 (4.15) ◽  
pp. 240
Author(s):  
Nur Hairani Abd Rahman ◽  
Muhammad Asri Mohd Ali ◽  
Mohammed Farhan Md. Yusof
Keyword(s):  
Blood Supply ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Public Awareness ◽  
Supply And Demand ◽  
Current Situation ◽  
Blood Collection ◽  
Volunteer Blood Donor ◽  
The Government

Millions of people need blood because of many reasons such as accidents, routine surgeries, treatment of serious diseases such as cancer and thalassemia. In many countries, the availability of blood product depends on a small number of volunteer donors, including Malaysia. Present trends in blood collection and capacity usage in Malaysia have raised concerns about the ability to meet potential needs. To ensure an adequate blood supply in health facilities is a challenging task for the government especially Ministry of Health Malaysia. It is important to develop a program with influential initiatives that can help to boost public interest and willingness to involve in blood donation program. This study aims to identify and examine the initiatives conducted by the government in order to attract the interest of public to become volunteer blood donor. This study identified that there were five main initiatives implemented by the government to attract public to donate blood, namely: (a) intensive advertising (via mainstream television and radio channels); (b) mobile blood transfusion service center; (c) incentives to blood donors; (d) establishments of donation suites, and; (e) collaboration with other government institution for blood donation campaign. Although current situation showed significant changes in terms of public awareness and willingness towards this program, but there are rooms for improvement for the government to consider in maintaining the balance between blood supply and demand in the country. Focusing on public to register, as frequent or repeated volunteer blood donor, is obviously one of the main available option that current situation need to strengthen. 

scholarly journals Design of Blood Supply Chain and Application to Marmara Region in Turkey

2019 ◽  
Vol 4 (3) ◽  
pp. 27-36
Author(s):  
Liban Ali Mohamed ◽  
Osman Yazicioglu ◽  
Oguz Borat
Keyword(s):  
Supply Chain ◽  
Blood Transfusion ◽  
Blood Supply ◽  
Blood Donation ◽  
Transportation Costs ◽  
Mixed Integer ◽  
Marmara Region ◽  
Blood Products ◽  
Blood Supply Chain ◽  
General Algebraic Modeling System

Blood transfusion is needed due to operations, diseases or accidents. Millions of people's health depends on the success of their blood transfusion. Planning and management is required to supply blood, test against diseases, produce blood products, store t hem and transport them to hospitals. A blood supply chain network design such as Blood Donation Centers (CBM), Regional Blood Centers (RBC), Destruction Centers (DM), and hospitals are addressed. To formulate the problem, the General Algebraic Modeling System (GAMS) software was applied to the Mixed Integer Model. When the number of RBC in Marmara region decreased from 3 to 2, opening and transportation costs increased to $5.37 million. When the number of RBCs increased from 3 to 4, opening and transportation costs decreased to $3.94 million.

Blood supply chain operation considering lifetime and transshipment under uncertain environment

2021 ◽  
pp. 107364
Author(s):  
Yufeng Zhou ◽  
Tiange Zou ◽  
Changshi Liu ◽  
Hongxia Yu ◽  
Liangyong Chen ◽  
...  
Keyword(s):  
Supply Chain ◽  
Blood Supply ◽  
Uncertain Environment ◽  
Chain Operation ◽  
Blood Supply Chain ◽  
Supply Chain Operation
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