scholarly journals Based on the Beers Criteria 2019 Edition Over-the-Counter Drugs Risk Confirmation of Elderly Chinese

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Yongyu Yang ◽  
Lu Zhang ◽  
Yamin Huang ◽  
Hangxing Huang ◽  
Shusen Sun ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Inappropriate Medication ◽  
Community Pharmacists ◽  
The Elderly ◽  
Drug Event ◽  
Beers Criteria ◽  
High Detection Rate ◽  
Over The Counter ◽  
Medical Practitioners ◽  
National Medical

Objective. To explore OTC (over-the-counter drugs) in Chinese community pharmacies often causes ADE (adverse drug event) in elderly patients. Methods. Use the drugs in the Beers Criteria 2019 potentially inappropriate medication use (PIM) list as search terms. Search for drugs registered on the National Medical Products Administration of China website before December 2019 to determine the drugs containing PIM active ingredients and, then, search the Chinese OTC selection and conversion catalog database to determine it as OTC. Two databases are considered to be the same drug if they have the same drug composition. Results. The incidence of PIM in elderly patients in our community is relatively high, and the management of OTC may be related to risk factors. Statistics found that 71 OTC contained the Beers Criteria ingredients, including 65 chemicals and six Chinese patent medicines. Varieties of compound preparations accounted for 78.9% and cold medicines accounted for 47.9%. Conclusions. The high detection rate of the Beers Criteria in Chinese OTC suggests that medical practitioners in China, especially community pharmacists, should pay attention to the rational use of OTC in the elderly.

A Closer Look at the 2015 Beers Criteria

2016 ◽  
Vol 30 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Rebecca L. Salbu ◽  
Judith Feuer
Keyword(s):  
Elderly Patients ◽  
Health Care Providers ◽  
Clinical Judgment ◽  
The Elderly ◽  
Specific Information ◽  
Beers Criteria ◽  
Potentially Inappropriate Medications ◽  
Care Providers ◽  
Inappropriate Medications ◽  
Made In

The Beers Criteria identifies potentially inappropriate medications for patients who are 65 years of age and older. Initially published in 1991, the criteria have been updated multiple times, most recently in 2015. The Beers Criteria is a tool designed to alert health-care providers to the potential harms of specific medications so they may better tailor therapeutic regimens for their elderly patients. The expert panel of the 2015 update made changes to a number of previous recommendations and provided 2 new tables on select drug interactions and select medications requiring renal dose adjustments. The purpose of this review is to provide additional details and rationale behind selected noteworthy changes within the 2015 criteria. Specific information is provided on the changes in recommendations for the use of nitrofurantoin, antiarrhythmics, nonbenzodiazepine receptor agonist hypnotics, antipsychotics, and proton pump inhibitors in the elderly. Additional comparisons are made between the 2012 recommendations and newer recommendations made in the 2015 update, along with rationale for the change. This review will allow practitioners to apply the 2015 Beers Criteria and integrate their clinical judgment when evaluating and selecting drug therapy for elderly patients.

Changes in Pharmacokinetics and Pharmacodynamics in the Elderly Patient

2007 ◽  
Vol 20 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Lisa C. Hutchison ◽  
Catherine E. O'Brien
Keyword(s):  
Elderly Patient ◽  
Elderly Patients ◽  
The Elderly ◽  
Pharmacokinetic Parameters ◽  
Beers Criteria ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Drug Dosing ◽  
Central Nervous System Agents ◽  
The Common ◽  
Pharmacologic Agents

The use of pharmacologic agents in elderly patients is one of the most difficult aspects of patient care. An understanding of the common physiologic changes expected with aging is helpful to anticipate changes expected in pharmacokinetic parameters. Distribution, metabolism, and excretion are significantly altered for many drugs. In addition, pharmacodynamic variations in elderly patients may increase or decrease sensitivity to a medication independent of pharmacokinetic changes. These alterations are particularly noteworthy with cardiovascular and central nervous system agents. Current controversies regarding the application of estimation of renal function to drug dosing and use of the Beers criteria of medications potentially inappropriate in the elderly are discussed.

scholarly journals Adverse drug events leading to emergency department visits in elderly: the role of inappropriate prescription

2010 ◽  
Vol 8 (2) ◽  
pp. 175-179 ◽  
Author(s):  
José Marcelo Farfel ◽  
Tarso Augusto Duenhas Accorsi ◽  
Marcelo Franken ◽  
Sueli Pinto Doudement ◽  
Mariane Moran ◽  
...  
Keyword(s):  
Emergency Department ◽  
Adverse Drug Events ◽  
Inappropriate Medication ◽  
Albert Einstein ◽  
The Elderly ◽  
Emergency Department Visits ◽  
Drug Event ◽  
Inappropriate Prescription ◽  
The Mean

ABSTRACT Objective: Adverse drug reactions are more incident among the elderly and are frequently associated to inappropriate prescription for this group. The objective of the current study was to investigate the incidence and the characteristics of emergency department visits, related to inappropriate prescription, at the Hospital Israelita Albert Einstein. Methods: Patients aged 60 years or older, admitted to the emergency department at Unidade Avançada Ibirapuera of Hospital Israelita Albert Einstein, were included in the study. Potentially inappropriate medication for the elderly was evaluated using updated 2003 Beers criteria. Results: Over a period of 6 months, 214 individuals were included in the study, being 53.7% male. The mean age was 70.8 years (60-107). A total of 48 registries of inappropriate prescription were recorded in 42 patients (19.6% of sample). An emergency visit related to adverse drug event was verified in 27 individuals (12.5% of the sample). From these patients, 34.5% were admitted to the emergency department because of an adverse event caused by an inappropriate medication. Conclusion: Inappropriate prescription is frequent among elderly patients admitted to emergency department. A surveillance system and a program to educate physicians on the most recent criteria of appropriate prescription may help reducing emergency visits and adverse drug events in the elderly population.

Recent Advances in Geriatrics: Drug-Related Problems in the Elderly

2000 ◽  
Vol 34 (3) ◽  
pp. 360-365 ◽  
Author(s):  
Joseph T Hanlon ◽  
Leslie A Shimp ◽  
Todd P Semla
Keyword(s):  
Elderly Patients ◽  
Pharmacy Practice ◽  
Care Facility ◽  
The Elderly ◽  
Drug Event ◽  
Inappropriate Drug ◽  
Future Research ◽  
Drug Related Problems ◽  
Related Factors ◽  
Term Care

OBJECTIVE: To review recent articles examining drug-related problems in the elderly and comment on their potential impact on geriatric pharmacy practice. DATA SOURCES: Six articles published in 1997 and 1998. DATA SYNTHESIS: One study estimated that the cost of drug-related morbidity and mortality with the services of consultant pharmacists was $4 billion, compared with $7.6 billion without the services of consultant pharmacists. A study of ambulatory elderly patients with polypharmacy documented that 35% reported experiencing at least one adverse drug event within the previous year. Another study of ambulatory elderly found that in those with discontinued medications, adverse drug withdrawal events were uncommon. Two studies, one from Canada and one from the US, describe the development, by consensus, of explicit criteria for defining and identifying inappropriate drug use in the elderly (i.e., drugs to avoid, drugs with dose limits, drug–drug and drug–disease interactions). Finally, a modified Delphi survey of an expert panel reached consensus on 18 potential risk factors for drug-related factors in long-term care facility residents. CONCLUSIONS: Drug-related problems are considerable for elderly patients. Data from published studies should provide some guidance for today's practitioners as well as direction regarding future research.

Identification and evaluation of potentially inappropriate medications (PIMs) in hospitalized geriatric patients using Beers criteria

2015 ◽  
Vol 26 (4) ◽  
Author(s):  
Pattani Danisha ◽  
Chandrasekhar Dilip ◽  
Panakkal Linu Mohan ◽  
Cholamugath Shinu ◽  
Jaffer Chalil Parambil ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Geriatric Patients ◽  
Adverse Drug Events ◽  
Inappropriate Medication ◽  
Drug Event ◽  
Beers Criteria ◽  
Potentially Inappropriate Medications ◽  
Close Monitoring ◽  
Entire Study ◽  
Hospitalized Elderly

AbstractThe aim of the study was to identify and evaluate potentially inappropriate medication (PIM) in geriatric patients using Beers criteria and also to identify adverse drug events (ADEs) due to PIMs and various drug-drug interactions.The medications in the prescriptions of patients above 60 years of age, their dosage regimen respective of their diagnosis were analyzed. Each medication was then checked with Beers list tables, and any medication if mentioned in the Beers list, was noted along with its strength of recommendation and quality of evidence. Any adverse drug event (ADE) due to PIM was identified. Causality of the events was assessed by Naranjo’s Scale. The number of drug-drug interactions per prescription and the severity of each interaction were also analyzed. The collected data from 200 subjects were subjected to statistical treatments using Statistical Package for Social Sciences (SPSS) software version 16.0 for WINDOWS.Based on the Beers criteria 2012, 106 out of 200 (53%) prescriptions had at least one PIM prescribed. A sum of 1690 medications was prescribed as a whole for the entire study subjects. Among which, 134 PIMs were identified. Most commonly prescribed PIMs were benzodiazepines (39, 19.5%), followed by sliding scale use of insulin (31, 15.5%), and prazosin at a rate of 11.5% (23). A total of 10 ADEs were identified during the study. The average number of drug interactions observed among total samples was found to be 3.0±6.0 with 0±5.0 serious interactions, 2±4.0 significant interactions requiring close monitoring, and 0±6.0 minor interactions.The study shows high prevalence of prescribing PIMs in hospitalized elderly patients; PIM also caused incidence of ADEs; and serious drug-drug interactions were scarce among the patients.

Drug-related problems in the elderly

2012 ◽  
Vol 153 (49) ◽  
pp. 1926-1936 ◽  
Author(s):  
Andrea Bor ◽  
Mária Matuz ◽  
Péter Doró ◽  
Réka Viola ◽  
Gyöngyvér Soós
Keyword(s):  
Elderly Patients ◽  
Financial Burden ◽  
The Elderly ◽  
Developed Countries ◽  
Evidence Based ◽  
Beers Criteria ◽  
Drug Related Problems ◽  
Drug Reactions ◽  
Inappropriate Drugs

The aging population in developed countries is a growing problem nowadays. The burden on healthcare is particularly high, since the prevalence of the diseases, especially chronic diseases increases with age. Prevalence of polypharmacy is common among elderly patients. While comorbidities require usage of several active agents with evidence based indication, polypharmacy increases the likelihood of interactions and adverse drug reactions, reduces patient compliance, affects quality of life and puts a significant financial burden on the patient and society. In order to reduce drug-related problems among the elderly, different lists of potentially inappropriate drugs and doses were created. One of the earliest known lists is the “Beers criteria”. The use of listed drugs is risky and not recommended for elderly patients. Following foreign examples, a list was compiled and adapted to the Hungarian drug spectrum based on the main concerns and alternative therapeutic suggestions. Orv. Hetil., 2012, 153, 1926–1936.

PS02.172: ESOPHAGECTOMY FOR 70 YEARS OF AGE AND OLDER PATIENTS IN FUKUOKA HIGASHI NATIONAL MEDICAL CENTER

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 170-171
Author(s):  
Takefumi Ohga ◽  
Sosei Kuma ◽  
Takahiro Ezaki
Keyword(s):  
Esophageal Cancer ◽  
Elderly Patients ◽  
Conflicts Of Interest ◽  
Medical Center ◽  
The Elderly ◽  
Pulmonary Complications ◽  
Average Hospital ◽  
National Medical ◽  
Group I ◽  
Group Ii

Abstract Background The patients with esophageal cancer tend to be elder and men. The elderly patients have frequently dysfunction of critical organs. Surgical treatment for elderly esophageal cancer patients has been considered to be the most difficult and the operative indications remain controversial. Aim: The purpose of this study was to clarify the indications for an esophagectomy in elderly patients (especially patients over 70 years of age) with esophageal cancer. Methods A total of 27 patients with esophageal cancer who underwent an esophagectomy in the Department of Surgery, National Fukuoka-Higashi Medical Center from 2005 to 2014 were divided into two groups according to age, namely, groups I (< 70 years, n = 18) and II (> or = 70 years, n = 9). In group II, surgery was only done in patients with PS0 or 1, as well as almost normal cardiac and pulmonary functions. Results The morbidity rates of group I and II were 66% and 33%, respectively. Pulmonary complications in each groups occurred in 12% and 0%, respectively. In group II, the mortality and 30-day mortality rates were 0.0% and 0.0%, respectively, and pulmonary complications did not occurred (0.0%). The average hospital stay period after the operation in group I and II were 55.5 days and 50.4 days, respectively. The hospital mortality retes in group I and II were 5.56% and 0.0%, respectively. The number of 3 years above survival persons is three (16.7%) and four (44.0%) in group I and II. Conclusion In the elderly, careful perioperative management is needed while paying special attention to pulmonary complications. However, when the indications for surgery can be strictly determined, an esophagectomy is considered a viable treatment alternative with satisfactory prognosis even in patients 70 years of age and older without any increased morbidity or mortality. Disclosure All authors have declared no conflicts of interest.

PS02.164: ESOPHAGECTOMY FOR 70 YEARS OF AGE AND OLDER PATIENTS IN FUKUOKA HIGASHI NATIONAL MEDICAL CENTER

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 168-168
Author(s):  
Takefumi Ohga ◽  
Sosei Kuma ◽  
Takahiro Ezaki
Keyword(s):  
Esophageal Cancer ◽  
Elderly Patients ◽  
Conflicts Of Interest ◽  
Medical Center ◽  
The Elderly ◽  
Pulmonary Complications ◽  
Average Hospital ◽  
National Medical ◽  
Group I ◽  
Group Ii

Abstract Background The patients with esophageal cancer tend to be elder and men. The elderly patients have frequently dysfunction of critical organs. Surgical treatment for elderly esophageal cancer patients has been considered to be the most difficult and the operative indications remain controversial. Aim: The purpose of this study was to clarify the indications for an esophagectomy in elderly patients (especially patients over 70 years of age) with esophageal cancer. Methods A total of 27 patients with esophageal cancer who underwent an esophagectomy in the Department of Surgery, National Fukuoka-Higashi Medical Center from 2005 to 2014 were divided into two groups according to age, namely, groups I (< 70 years, n = 18) and II (> or = 70 years, n = 9). In group II, surgery was only done in patients with PS0 or 1, as well as almost normal cardiac and pulmonary functions. Results The morbidity rates of group I and II were 66% and 33%, respectively. Pulmonary complications in each groups occurred in 12% and 0%, respectively. In group II, the mortality and 30-day mortality rates were 0.0% and 0.0%, respectively, and pulmonary complications did not occurred (0.0%). The average hospital stay period after the operation in group I and II were 55.5 days and 50.4 days, respectively. The hospital mortality retes in group I and II were 5.56% and 0.0%, respectively. The number of 3 years above survival persons is three (16.7%) and four (44.0%) in group I and II. Conclusion Discussion: In the elderly, careful perioperative management is needed while paying special attention to pulmonary complications. However, when the indications for surgery can be strictly determined, an esophagectomy is considered a viable treatment alternative with satisfactory prognosis even in patients 70 years of age and older without any increased morbidity or mortality. Disclosure All authors have declared no conflicts of interest.

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