scholarly journals Co-Occurrence of SARS-CoV-2 Infection and Inactivated SARS-CoV-2 Vaccination among Healthcare Workers

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Cucunawangsih Cucunawangsih ◽  
Ratna Sari Wijaya ◽  
Nata Pratama Hardjo Lugito ◽  
Ivet Suriapranata
Keyword(s):  
Antibody Response ◽  
Healthcare Workers ◽  
Vaccination Campaign

The presented cases describe the concurrent SARS-CoV-2 infection and inactivated SARS-CoV-2 vaccination among eight healthcare workers (HCWs). These cases highlighted the importance of broad hospital screening during the COVID-19 vaccination campaign. Further study regarding the durability of antibody response induced by infection and first-dose vaccination is required to determine the appropriate time for giving a second dose of inactivated SARS-CoV-2 vaccine among these cases.

Antibody response to the influenza vaccine in healthcare workers

Vaccine ◽  
2012 ◽  
Vol 30 (2) ◽  
pp. 436-441 ◽  
Author(s):  
Ema Sacadura-Leite ◽  
Antonio Sousa-Uva ◽  
Helena Rebelo-de-Andrade
Keyword(s):  
Antibody Response ◽  
Influenza Vaccine ◽  
Healthcare Workers

scholarly journals COVID-19 Vaccine Intention among Healthcare Workers in Saudi Arabia: A Cross-Sectional Survey

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 835
Author(s):  
Mohammed Noushad ◽  
Mohammad Zakaria Nassani ◽  
Anas B. Alsalhani ◽  
Pradeep Koppolu ◽  
Fayez Hussain Niazi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Healthcare System ◽  
Healthcare Workers ◽  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Herd Immunity ◽  
Positive Sign ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Public Health Strategies

The COVID-19 pandemic has caused largescale morbidity and mortality and a tremendous burden on the healthcare system. Healthcare workers (HCWs) require adequate protection to avoid onward transmission and minimize burden on the healthcare system. Moreover, HCWs can also influence the general public into accepting the COVID-19 vaccine. Therefore, determining COVID-19 vaccine intention among HCWs is of paramount importance to plan tailor-made public health strategies to maximize vaccine coverage. A structured questionnaire was administered in February and March 2021 among HCWs in Saudi Arabia using convenience sampling, proceeding the launch of the vaccination campaign. HCWs from all administrative regions of Saudi Arabia were included in the study. In total, 674 out of 1124 HCWs responded and completed the survey (response rate 59.9%). About 65 percent of the HCWs intended to get vaccinated. The intention to vaccinate was significantly higher among HCWs 50 years of age or older, Saudi nationals and those who followed the updates about COVID-19 vaccines (p < 0.05). The high percentage (26 percent) of those who were undecided in getting vaccinated is a positive sign. As the vaccination campaign gathers pace, the attitude is expected to change over time. Emphasis should be on planning healthcare strategies to convince the undecided HCWs into accepting the vaccine in order to achieve the coverage required to achieve herd immunity.

scholarly journals Neutralizing Anti-SARS-CoV-2 Antibody Titer and Reported Adverse Effects, in a Sample of Italian Nursing Home Personnel after Two Doses of the BNT162b2 Vaccine Administered Four Weeks Apart

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 652
Author(s):  
Alberto Modenese ◽  
Stefania Paduano ◽  
Annalisa Bargellini ◽  
Rossana Bellucci ◽  
Simona Marchetti ◽  
...  
Keyword(s):  
Nursing Home ◽  
Adverse Effects ◽  
Antibody Titer ◽  
Healthcare Workers ◽  
Vaccination Campaign ◽  
Northern Italy ◽  
High Antibody ◽  
Protective Level ◽  
High Antibody Titer ◽  
Main Factors

Background: The immunization of healthcare workers (HCWs) plays a recognized key role in prevention in the COVID-19 pandemic: in Italy, the vaccination campaign began at the end of December 2020. A better knowledge of the on-field immune response in HCWs, of adverse effects and of the main factors involved is fundamental. Methods: We performed a study on workers at a nursing home in Northern Italy, vaccinated in January–February 2021 with two doses of the BNT162b2 vaccine four weeks apart, instead of the three weeks provided for in the original manufacturer protocol. One month after the second dose, the serological titer of IgG-neutralizing anti-RBD antibodies of the subunit S1 of the spike protein of SARS-CoV-2 was determined. The socio-demographic and clinical characteristics of the subjects and adverse effects of vaccination were collected by questionnaire. Results: In all of the workers, high antibody titer, ranging between 20 and 760 times the minimum protective level were observed. Titers were significantly higher in subjects with a previous COVID-19 diagnosis. Adverse effects after the vaccine were more frequent after the second dose, but no severe adverse effects were observed. Conclusions: The two doses of the BNT162b2 vaccine, even if administered four weeks apart, induced high titers of anti-SARS-CoV-2 neutralizing IgG in all the operators included in the study.

scholarly journals Reactogenicity, safety and antibody response, after one and two doses of mRNA-1273 in seronegative and seropositive healthcare workers

2021 ◽  
Author(s):  
Marie Tré-Hardy ◽  
Roberto Cupaiolo ◽  
Emmanuelle Papleux ◽  
Alain Wilmet ◽  
Alexandra Horeanga ◽  
...  
Keyword(s):  
Antibody Response ◽  
Healthcare Workers

SARS-CoV-2 Antibody Response Following SPUTNIK V Vaccination in Healthcare Workers From a Hospital in Argentina: Preliminary Results

2021 ◽  
Author(s):  
Angela Gentile ◽  
Vanesa Edelvais Castellano ◽  
Natacha Weinberger ◽  
Anabella Cecilia Pacchiotti ◽  
Sofia María Diana Menendez ◽  
...  
Keyword(s):  
Antibody Response ◽  
Healthcare Workers ◽  
Preliminary Results

scholarly journals COVID-19 convalescent plasma donors: impact of vaccination on antibody levels, breakthrough infections and reinfection rate.

2021 ◽  
Author(s):  
Massimo La Raja ◽  
Monia Pacenti ◽  
Ileana Grimaldi ◽  
Caterina Boldrin ◽  
Margherita Cattai ◽  
...  
Keyword(s):  
Antibody Response ◽  
Antibody Level ◽  
Natural Infection ◽  
Vaccination Campaign ◽  
Reinfection Rate ◽  
Post Vaccination ◽  
Exponential Increase ◽  
The One ◽  
Antibody Levels ◽  
The Impact

From April 2020 through May 2021 in Padova Province 3395 COVID-19 recovered patients were recruited as potential convalescent plasma donors and tested for SARS-CoV-2 antibodies. Since January 2021 COVID-19 vaccination campaign began in Italy, the impact of vaccination on antibody levels and suspect vaccine breakthrough infections in these subjects were investigated. Post-vaccination anti-Sars-Cov-2 antibody level in 54 previously infected subjects had an exponential increase compared to pre-vaccination level regardless of the number of vaccine doses. However after 100 days from vaccination SARS-CoV-2 antibody level tends to decline. Post-vaccination primary infections were detected in 15 cases, with 3 possible breakthrough infections after a full vaccination course. In these cases, antibody response after infection was present but weaker than the one of subjects vaccinated after natural infection. A trend toward stronger antibody response was observed with increasing distance between natural infection and vaccination. Additionally, 2 cases of asymptomatic reinfections are also discussed.

scholarly journals EVALUATION OF ANTIBODY RESPONSE AFTER COVID‐19 VACCINATION OF HEALTHCARE WORKERS

2021 ◽  
Author(s):  
Elif Bilge Uysal ◽  
Sibel Gümüş ◽  
Bayhan Bektöre ◽  
Hale Bozkurt ◽  
Ayşegül Gözalan
Keyword(s):  
Antibody Response ◽  
Healthcare Workers

scholarly journals Promotion of the influenza vaccination to hospital staff during pre-employment health check: a prospective, randomised, controlled trial

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Michael Currat ◽  
Catherine Lazor-Blanchet ◽  
Giorgio Zanetti
Keyword(s):  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Healthcare Workers ◽  
Vaccination Campaign ◽  
Intervention Group ◽  
Vaccination Rate ◽  
Health Check ◽  
Control Group ◽  
Vaccination Rates ◽  
Newly Hired

Abstract Background Vaccination is the most effective prevention of seasonal influenza. Despite its recommendation and active promotion, vaccination coverage remains low among healthcare staff. The goal of the study was to test if a pre-employment health check is a good opportunity to promote future vaccination against influenza among healthcare workers newly hired by a university hospital. Methods All new hospital employees active at the bedside who underwent a pre-employment health check between the end of 2016’s influenza epidemic and the start of the next influenza vaccination campaign were randomly allocated to a control group or an intervention group. The intervention consisted of a semi-structured dialog and the release of an information leaflet about influenza and influenza vaccination during the check-up, and the shipment of a postcard reminder 2 weeks before the next vaccination campaign. Vaccination rates during the campaign were compared among the two groups. Results Three hundred fifty-seven employees were included. Vaccination rates were similar in both groups: 79/172 (46%) in the control and 92/185 (50%) in the intervention group. A significantly higher rate of vaccination was noted among physicians (70/117, 60%) than among other employees (101/240, 42%, p = 0.001). In a pre-defined exploratory analysis among physicians, the vaccination rate was higher in the intervention group (36/51, 71%) than in the control group (34/65, 52%, p = 0.046). Conclusions Promotion of the influenza vaccine during pre-employment health check did not improve the vaccination rate of newly hired hospital healthcare workers overall during the next influenza vaccination campaign. Results suggest a favourable impact on the vaccination rate of physicians. Thus, there may be an interest in using communication strategies tailored to the different categories of healthcare workers to promote the influenza vaccine during pre-employment health check. Trial registration ClinicalTrials, NCT02758145. Registered 26 April 2016.

Description of an Influenza Vaccination Campaign and Use of a Randomized Survey to Determine Participation Rates

2010 ◽  
Vol 31 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Xuguang (Grant) Tao ◽  
Janine Giampino ◽  
Deborah A. Dooley ◽  
Frances E. Humphrey ◽  
David M. Baron ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Healthcare Workers ◽  
Vaccination Campaign ◽  
Vaccination Rate ◽  
Patient Contact ◽  
Participation Rates ◽  
Immunization Program ◽  
Influenza Immunization ◽  
Direct Patient Contact ◽  
Johns Hopkins University

Objectives.To describe the procedures used during an influenza immunization program and the use of a randomized survey to quantify the vaccination rate among healthcare workers with and without patient contact.Design.Influenza immunization vaccination program and a randomized survey.Setting.Johns Hopkins University and Health System.Methods.The 2008/2009 Johns Hopkins Influenza Immunization Program was administered to 40,000 employees, including 10,763 healthcare workers. A 10% randomized sample (1,084) of individuals were interviewed to evaluate the vaccination rate among healthcare workers with direct patient contact.Results.Between September 23, 2008, and April 30, 2009, a total of 16,079 vaccinations were administered. Ninety-four percent (94.5%) of persons who were vaccinated received the vaccine in the first 7 weeks of the campaign. The randomized survey demonstrated an overall vaccination rate of 71.3% (95% confidence interval, 68.6%-74.0%) and a vaccination rate for employees with direct patient contact of 82.8% (95% confidence interval, 80.1%-85.5%). The main reason (25.3%) for declining the program vaccine was because the employee had received documented vaccination elsewhere.Conclusions.The methods used to increase participation in the recent immunization program were successful, and a randomized survey to assess participation was found to be an efficient means of evaluating the workforce's level of potential immunity to the influenza virus.

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