scholarly journals A Novel Context Aware Joint Segmentation and Classification Framework for Glaucoma Detection

2021 ◽  
Vol 2021 ◽  
pp. 1-19
Author(s):  
S. Sankar Ganesh ◽  
G. Kannayeram ◽  
Alagar Karthick ◽  
M. Muhibbullah

Glaucoma is a chronic ocular disease characterized by damage to the optic nerve resulting in progressive and irreversible visual loss. Early detection and timely clinical interventions are critical in improving glaucoma-related outcomes. As a typical and complicated ocular disease, glaucoma detection presents a unique challenge due to its insidious onset and high intra- and interpatient variabilities. Recent studies have demonstrated that robust glaucoma detection systems can be realized with deep learning approaches. The optic disc (OD) is the most commonly studied retinal structure for screening and diagnosing glaucoma. This paper proposes a novel context aware deep learning framework called GD-YNet, for OD segmentation and glaucoma detection. It leverages the potential of aggregated transformations and the simplicity of the YNet architecture in context aware OD segmentation and binary classification for glaucoma detection. Trained with the RIGA and RIMOne-V2 datasets, this model achieves glaucoma detection accuracies of 99.72%, 98.02%, 99.50%, and 99.41% with the ACRIMA, Drishti-gs, REFUGE, and RIMOne-V1 datasets. Further, the proposed model can be extended to a multiclass segmentation and classification model for glaucoma staging and severity assessment.

2021 ◽  
Vol 11 (11) ◽  
pp. 4753
Author(s):  
Gen Ye ◽  
Chen Du ◽  
Tong Lin ◽  
Yan Yan ◽  
Jack Jiang

(1) Background: Deep learning has become ubiquitous due to its impressive performance in various domains, such as varied as computer vision, natural language and speech processing, and game-playing. In this work, we investigated the performance of recent deep learning approaches on the laryngopharyngeal reflux (LPR) diagnosis task. (2) Methods: Our dataset is composed of 114 subjects with 37 pH-positive cases and 77 control cases. In contrast to prior work based on either reflux finding score (RFS) or pH monitoring, we directly take laryngoscope images as inputs to neural networks, as laryngoscopy is the most common and simple diagnostic method. The diagnosis task is formulated as a binary classification problem. We first tested a powerful backbone network that incorporates residual modules, attention mechanism and data augmentation. Furthermore, recent methods in transfer learning and few-shot learning were investigated. (3) Results: On our dataset, the performance is the best test classification accuracy is 73.4%, while the best AUC value is 76.2%. (4) Conclusions: This study demonstrates that deep learning techniques can be applied to classify LPR images automatically. Although the number of pH-positive images used for training is limited, deep network can still be capable of learning discriminant features with the advantage of technique.


Author(s):  
Bosede Iyiade Edwards ◽  
Nosiba Hisham Osman Khougali ◽  
Adrian David Cheok

With recent focus on deep neural network architectures for development of algorithms for computer-aided diagnosis (CAD), we provide a review of studies within the last 3 years (2015-2017) reported in selected top journals and conferences. 29 studies that met our inclusion criteria were reviewed to identify trends in this field and to inform future development. Studies have focused mostly on cancer-related diseases within internal medicine while diseases within gender-/age-focused fields like gynaecology/pediatrics have not received much focus. All reviewed studies employed image datasets, mostly sourced from publicly available databases (55.2%) and few based on data from human subjects (31%) and non-medical datasets (13.8%), while CNN architecture was employed in most (70%) of the studies. Confirmation of the effect of data manipulation on quality of output and adoption of multi-class rather than binary classification also require more focus. Future studies should leverage collaborations with medical experts to aid future with actual clinical testing with reporting based on some generally applicable index to enable comparison. Our next steps on plans for CAD development for osteoarthritis (OA), with plans to consider multi-class classification and comparison across deep learning approaches and unsupervised architectures were also highlighted.


2021 ◽  
Author(s):  
Monika Jyotiyana ◽  
Nishtha Kesswani ◽  
Munish Kumar

Abstract Deep learning techniques are playing an important role in the classification and prediction of diseases. Undoubtedly deep learning has a promising future in the health sector, especially in medical imaging. The popularity of deep learning approaches is because of their ability to handle a large amount of data related to the patients with accuracy, reliability in a short span of time. However, the practitioners may take time in analyzing and generating reports. In this paper, we have proposed a Deep Neural Network-based classification model for Parkinson’s disease. Our proposed method is one such good example giving faster and more accurate results for the classification of Parkinson’s disease patients with excellent accuracy of 94.87%. Based on the attributes of the dataset of the patient, the model can be used for the identification of Parkinsonism's. We have also compared the results with other existing approaches like Linear Discriminant Analysis, Support Vector Machine, K-Nearest Neighbor, Decision Tree, Classification and Regression Trees, Random Forest, Linear Regression, Logistic Regression, Multi-Layer Perceptron, and Naive Bayes.


2021 ◽  
Vol 12 ◽  
Author(s):  
Alexander C. Constantino ◽  
Nathaniel D. Sisterson ◽  
Naoir Zaher ◽  
Alexandra Urban ◽  
R. Mark Richardson ◽  
...  

Background: Decision-making in epilepsy surgery is strongly connected to the interpretation of the intracranial EEG (iEEG). Although deep learning approaches have demonstrated efficiency in processing extracranial EEG, few studies have addressed iEEG seizure detection, in part due to the small number of seizures per patient typically available from intracranial investigations. This study aims to evaluate the efficiency of deep learning methodology in detecting iEEG seizures using a large dataset of ictal patterns collected from epilepsy patients implanted with a responsive neurostimulation system (RNS).Methods: Five thousand two hundred and twenty-six ictal events were collected from 22 patients implanted with RNS. A convolutional neural network (CNN) architecture was created to provide personalized seizure annotations for each patient. Accuracy of seizure identification was tested in two scenarios: patients with seizures occurring following a period of chronic recording (scenario 1) and patients with seizures occurring immediately following implantation (scenario 2). The accuracy of the CNN in identifying RNS-recorded iEEG ictal patterns was evaluated against human neurophysiology expertise. Statistical performance was assessed via the area-under-precision-recall curve (AUPRC).Results: In scenario 1, the CNN achieved a maximum mean binary classification AUPRC of 0.84 ± 0.19 (95%CI, 0.72–0.93) and mean regression accuracy of 6.3 ± 1.0 s (95%CI, 4.3–8.5 s) at 30 seed samples. In scenario 2, maximum mean AUPRC was 0.80 ± 0.19 (95%CI, 0.68–0.91) and mean regression accuracy was 6.3 ± 0.9 s (95%CI, 4.8–8.3 s) at 20 seed samples. We obtained near-maximum accuracies at seed size of 10 in both scenarios. CNN classification failures can be explained by ictal electro-decrements, brief seizures, single-channel ictal patterns, highly concentrated interictal activity, changes in the sleep-wake cycle, and progressive modulation of electrographic ictal features.Conclusions: We developed a deep learning neural network that performs personalized detection of RNS-derived ictal patterns with expert-level accuracy. These results suggest the potential for automated techniques to significantly improve the management of closed-loop brain stimulation, including during the initial period of recording when the device is otherwise naïve to a given patient's seizures.


Cryptography ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 30
Author(s):  
Bang Yuan Chong ◽  
Iftekhar Salam

This paper studies the use of deep learning (DL) models under a known-plaintext scenario. The goal of the models is to predict the secret key of a cipher using DL techniques. We investigate the DL techniques against different ciphers, namely, Simplified Data Encryption Standard (S-DES), Speck, Simeck and Katan. For S-DES, we examine the classification of the full key set, and the results are better than a random guess. However, we found that it is difficult to apply the same classification model beyond 2-round Speck. We also demonstrate that DL models trained under a known-plaintext scenario can successfully recover the random key of S-DES. However, the same method has been less successful when applied to modern ciphers Speck, Simeck, and Katan. The ciphers Simeck and Katan are further investigated using the DL models but with a text-based key. This application found the linear approximations between the plaintext–ciphertext pairs and the text-based key.


Sensors ◽  
2021 ◽  
Vol 21 (22) ◽  
pp. 7519
Author(s):  
Sakorn Mekruksavanich ◽  
Anuchit Jitpattanakul

Smartphones as ubiquitous gadgets are rapidly becoming more intelligent and context-aware as sensing, networking, and processing capabilities advance. These devices provide users with a comprehensive platform to undertake activities such as socializing, communicating, sending and receiving e-mails, and storing and accessing personal data at any time and from any location. Nowadays, smartphones are used to store a multitude of private and sensitive data including bank account information, personal identifiers, account passwords and credit card information. Many users remain permanently signed in and, as a result, their mobile devices are vulnerable to security and privacy risks through assaults by criminals. Passcodes, PINs, pattern locks, facial verification, and fingerprint scans are all susceptible to various assaults including smudge attacks, side-channel attacks, and shoulder-surfing attacks. To solve these issues, this research introduces a new continuous authentication framework called DeepAuthen, which identifies smartphone users based on their physical activity patterns as measured by the accelerometer, gyroscope, and magnetometer sensors on their smartphone. We conducted a series of tests on user authentication using several deep learning classifiers, including our proposed deep learning network termed DeepConvLSTM on the three benchmark datasets UCI-HAR, WISDM-HARB and HMOG. Results demonstrated that combining various motion sensor data obtained the highest accuracy and energy efficiency ratio (EER) values for binary classification. We also conducted a thorough examination of the continuous authentication outcomes, and the results supported the efficacy of our framework.


2021 ◽  
Vol 11 (10) ◽  
pp. 628
Author(s):  
Allan B. I. Bernardo ◽  
Macario O. Cordel ◽  
Rochelle Irene G. Lucas ◽  
Jude Michael M. Teves ◽  
Sashmir A. Yap ◽  
...  

Filipino students ranked last in reading proficiency among all countries/territories in the PISA 2018, with only 19% meeting the minimum (Level 2) standard. It is imperative to understand the range of factors that contribute to low reading proficiency, specifically variables that can be the target of interventions to help students with poor reading proficiency. We used machine learning approaches, specifically binary classification methods, to identify the variables that best predict low (Level 1b and lower) vs. higher (Level 1a or better) reading proficiency using the Philippine PISA data from a nationally representative sample of 15-year-old students. Several binary classification methods were applied, and the best classification model was derived using support vector machines (SVM), with 81.2% average test accuracy. The 20 variables with the highest impact in the model were identified and interpreted using a socioecological perspective of development and learning. These variables included students’ home-related resources and socioeconomic constraints, learning motivation and mindsets, classroom reading experiences with teachers, reading self-beliefs, attitudes, and experiences, and social experiences in the school environment. The results were discussed with reference to the need for a systems perspective to addresses poor proficiency, requiring interconnected interventions that go beyond students’ classroom reading.


2020 ◽  
Vol 36 (11) ◽  
pp. 3507-3515
Author(s):  
Yunchuan Kong ◽  
Tianwei Yu

Abstract Motivation A unique challenge in predictive model building for omics data has been the small number of samples (n) versus the large amount of features (p). This ‘n≪p’ property brings difficulties for disease outcome classification using deep learning techniques. Sparse learning by incorporating known functional relationships between the biological units, such as the graph-embedded deep feedforward network (GEDFN) model, has been a solution to this issue. However, such methods require an existing feature graph, and potential mis-specification of the feature graph can be harmful on classification and feature selection. Results To address this limitation and develop a robust classification model without relying on external knowledge, we propose a forest graph-embedded deep feedforward network (forgeNet) model, to integrate the GEDFN architecture with a forest feature graph extractor, so that the feature graph can be learned in a supervised manner and specifically constructed for a given prediction task. To validate the method’s capability, we experimented the forgeNet model with both synthetic and real datasets. The resulting high classification accuracy suggests that the method is a valuable addition to sparse deep learning models for omics data. Availability and implementation The method is available at https://github.com/yunchuankong/forgeNet. Contact [email protected] Supplementary information Supplementary data are available at Bioinformatics online.


2021 ◽  
Vol 13 ◽  
Author(s):  
Pranav Mahajan ◽  
Veeky Baths

Current methods for early diagnosis of Alzheimer's Dementia include structured questionnaires, structured interviews, and various cognitive tests. Language difficulties are a major problem in dementia as linguistic skills break down. Current methods do not provide robust tools to capture the true nature of language deficits in spontaneous speech. Early detection of Alzheimer's Dementia (AD) from spontaneous speech overcomes the limitations of earlier approaches as it is less time consuming, can be done at home, and is relatively inexpensive. In this work, we re-implement the existing NLP methods, which used CNN-LSTM architectures and targeted features from conversational transcripts. Our work sheds light on why the accuracy of these models drops to 72.92% on the ADReSS dataset, whereas, they gave state of the art results on the DementiaBank dataset. Further, we build upon these language input-based recurrent neural networks by devising an end-to-end deep learning-based solution that performs a binary classification of Alzheimer's Dementia from the spontaneous speech of the patients. We utilize the ADReSS dataset for all our implementations and explore the deep learning-based methods of combining acoustic features into a common vector using recurrent units. Our approach of combining acoustic features using the Speech-GRU improves the accuracy by 2% in comparison to acoustic baselines. When further enriched by targeted features, the Speech-GRU performs better than acoustic baselines by 6.25%. We propose a bi-modal approach for AD classification and discuss the merits and opportunities of our approach.


2021 ◽  
Vol 23 (06) ◽  
pp. 10-22
Author(s):  
Ms. Anshika Shukla ◽  
◽  
Mr. Sanjeev Kumar Shukla ◽  

In recent years, there are various methods for source code classification using deep learning approaches have been proposed. The classification accuracy of the method using deep learning is greatly influenced by the training data set. Therefore, it is possible to create a model with higher accuracy by improving the construction method of the training data set. In this study, we propose a dynamic learning data set improvement method for source code classification using deep learning. In the proposed method, we first train and verify the source code classification model using the training data set. Next, we reconstruct the training data set based on the verification result. We create a high-precision model by repeating this learning and reconstruction and improving the learning data set. In the evaluation experiment, the source code classification model was learned using the proposed method, and the classification accuracy was compared with the three baseline methods. As a result, it was found that the model learned using the proposed method has the highest classification accuracy. We also confirmed that the proposed method improves the classification accuracy of the model from 0.64 to 0.96


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