scholarly journals Masticatory Ability for a Single Implant Mandibular Overdenture Retained by Two Different Attachments: A Randomized Controlled Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Marwa Abdel AaL ◽  
Amr Naguib ◽  
Ahmed Salah ◽  
Karim Foda ◽  
Nora Sheta ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Study Groups ◽  
Masticatory Ability ◽  
Edentulous Mandible ◽  
Significant Difference ◽  
The Mean ◽  
Edentulous Patients ◽  
Mandibular Overdenture ◽  
Single Implant

Objective. The aim of this randomized clinical trial was to compare the masticatory ability subjectively between ball and Cendres+Métaux Locator (CM-LOC) attachment for a single implant retained mandibular overdenture throughout a 24-month follow-up period. Materials and Methods. Eighty completely edentulous patients were recruited. All patients received new complete dentures, and masticatory ability was recorded using a questionnaire (baseline record). All patients received a single implant in the midline of the completely edentulous mandible. After 3-month healing period, patients were randomized using sealed envelopes into two groups: ball or CM-LOC attachment. The same masticatory ability questionnaire was used to record masticatory ability for both groups after 2 weeks of pickup and 3-, 6-, 9-, 12-, and 24-month follow-up. Comparison between the study groups was done using Mann–Whitney U test for independent samples. Two-sided P values less than 0.05 were considered statistically significant. Results. The mean masticatory scores improved for both attachments, with no statistically significant difference between them throughout the 24-month follow-up. The CM-LOC attachment group showed a greater improvement change in masticatory ability after 6- and 12-month follow-up (−12.47 ± 12.006, −11.46 ± 14.625; P = 0.826 ), while the ball attachment group showed a slight improvement after the 24-month follow-up (−11.72 ± 12.368, −10.88 ± 11.963; P = 0.778 ). Conclusion. Single implant retained mandibular overdenture improved masticatory ability subjectively with no significant difference between both attachments used although the ball attachment showed better masticatory ability scores after 24-month follow-up.

scholarly journals Implant Stability Changes for Nonsubmerged and Submerged Protocols for a Single Implant Mandibular Overdenture Using Ball Attachment

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Ahmed Salah ◽  
Karim Foda ◽  
Mohamed Farouk Abdalla ◽  
Marwa Abdel Aal ◽  
Amr Naguib ◽  
...  
Keyword(s):  
Study Groups ◽  
First Year ◽  
Implant Stability ◽  
Edentulous Mandible ◽  
Significant Difference ◽  
The Mean ◽  
Edentulous Patients ◽  
Mandibular Overdenture ◽  
Single Implant

Objectives. To compare the changes in implant stability for the nonsubmerged (NS) and submerged (S) protocols for the single implant retained mandibular overdenture using ball attachment throughout a 24-month follow-up. Materials and Methods. Eighty completely edentulous patients were seeking to improve retention of their lower complete denture by installing a single implant in the midline of the completely edentulous mandible. At the day of implant installation, patients were randomized into 2 groups using sealed envelopes: the nonsubmerged (NS) and submerged (S) group. After a 3-month healing period, all patients were randomized using sealed envelopes into ball attachment and CM-LOC attachment. The Periotest readings (PTV) was recorded using the Periotest M device and was recorded every 3 months for the first year and then annually in the second year. The scope of this clinical trial focused only on results of the ball attachment. The Mann–Whitney U test was used for comparison between study groups for independent samples. Two-sided p values less than 0.05 was considered statistically significant. Results. There was no statistically significant difference in the mean change in PTV reading between the NS and S group at the different follow-up intervals. Initially, at the day of pickup (baseline) and 3-month follow-up, the mean PTV reading for the NS was greater than that of the S group (−4.471 ± 1.489, −4.391 ± 1.4727 ( p = 0.913 )), while the S group has shown a greater improvement in PTV than the NS group after 6-month follow-up and continued throughout the 24-month follow-up (−5.730 ± 1.7804, −50855 ± 1.2581 ( p = 1 )). Conclusion. Both the nonsubmerged and the submerged healing protocol have shown reliable Periotest readings using ball attachment for a single implant retained overdenture. The submerged group has resulted in a greater improvement in Periotest readings after the 12- and 24-month follow-up period when compared to the nonsubmerged group although this improvement was not statistically significant.

scholarly journals Implant Stability Changes for a Single Implant Mandibular Overdenture

2021 ◽  
Author(s):  
Karim Fouda ◽  
Ahmed Fahmy ◽  
Khaled Aziz ◽  
Marwa Abdel Aal ◽  
Amr Naguib ◽  
...  
Keyword(s):  
Study Groups ◽  
First Year ◽  
Implant Stability ◽  
Edentulous Mandible ◽  
Significant Difference ◽  
Edentulous Patients ◽  
Mandibular Overdenture ◽  
To Receive ◽  
Single Implant

Abstract Objectives To compare the changes in implant stability for the nonsubmerged and submerged protocols for a single-implant retained mandibular overdenture using Cendres and Metaux Locator attachment throughout a 24-month follow-up. Materials and Methods Eighty edentulous patients who were seeking to install a single implant in the midline of the completely edentulous mandible. At the day of implant installation, patients were randomized into two groups using sealed envelopes: the nonsubmerged and submerged groups. After 3 months of healing period, randomization using sealed envelopes was performed and patients were randomized to receive the Cendres and Metaux Locator attachment. The periotest readings were recorded using the Periotest M device, every 3 months for the first year and annually in the second year. The scope of this clinical trial focused only on results of the Cendres and Metaux attachment. Statistical Analysis The Mann–Whitney U-test was used for comparison between study groups for independent samples. Two-sided p-values less than 0.05 were considered statistically significant. Results There was no statistically significant difference between the mean periotest readings of both groups throughout the 24-month follow-up. Both groups showed an improvement in mean periotest readings with the submerged group tending to show greater stability at 6, 12, and 24-month follow-ups. Conclusions The nonsubmerged and the submerged healing protocols resulted in reliable periotest readings with the submerged group showing greater improvement than the nonsubmerged, although this improvement is nonsignificant when using the Cendres and Metaux attachment for a single mandibular overdenture.

scholarly journals Influence of bevacizumab therapy and intraretinal hemorrhage in long-term outcomes of hemorrhagic retinal arterial macroaneurysm

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jae Hui Kim ◽  
Jong Woo Kim ◽  
Chul Gu Kim ◽  
Young Ju Lew ◽  
Han Joo Cho
Keyword(s):  
Multivariate Analysis ◽  
Study Groups ◽  
Final Visit ◽  
Observation Group ◽  
Retinal Arterial Macroaneurysm ◽  
Bevacizumab Treatment ◽  
Significant Difference ◽  
The Mean

AbstractThis study aimed to evaluate the long-term visual outcomes of hemorrhagic retinal arterial macroaneurysm (RAM), particularly focusing on the influence of bevacizumab therapy and intraretinal hemorrhage (IRH) on the outcomes. This retrospective study included 49 patients diagnosed with hemorrhagic RAM. Patients were divided into the bevacizumab group and observation group depending on the whether they were administered bevacizumab treatment and the IRH group and the non-IRH group based on the presence of IRH at the fovea. Best-corrected visual acuity (BCVA) at diagnosis was compared with that at the final visit. Further, the BCVA at the final visit was compared between the study groups. Multivariate analysis was also performed to identify factors associated with poor BCVA at the final visit. The mean follow-up period was 24.8 ± 15.3 months. The mean logarithm of minimal angle of resolution BCVA was significantly improved from 1.37 ± 0.70 at diagnosis to 0.72 ± 0.62 at the final visit (P < 0.001). There was no significant difference in the BCVA at the final visit between the bevacizumab group and observation group (P = 0.576). However, the BCVA at the final visit was significantly worse in the IRH group than in the non-IRH group (P = 0.002). In multivariate analysis, the presence of IRH was significantly associated with poor BCVA (P = 0.007). Significant long-term visual improvement was noted in hemorrhagic RAM. However, the presence of IRH at the fovea was associated with poor visual prognosis. Bevacizumab therapy did not significantly influence the outcomes.

scholarly journals Effects of a novel dye containing toothpaste versus regular fluoridated toothpaste for supragingival biofilm reduction in patients with chronic gingivitis: A Randomized Controlled Trial

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Avita Rath ◽  
Chong Junning ◽  
Priyadarshini HR ◽  
Brandon Nicholas Teo ◽  
Naik Hsian Zhen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Image Analysis ◽  
Controlled Trial ◽  
Control Group ◽  
Dental Biofilm ◽  
Randomized Controlled ◽  
Significant Difference ◽  
Tooth Surfaces ◽  
The Mean

AIM:To compare the effects of a plaque disclosing toothpaste with a regular fluoridated toothpaste for supragingival biofilm reduction in patients with chronic gingivitis.MATERIALS AND METHODS:This study was a randomized controlled trial with a parallel design. Forty patients, both males and females aged 18-25 years with chronic generalized gingivitis (N=40) were randomly allocated to two groups of twenty each (n=20), using lottery method. Participants in the experimental group brushed with a plaque disclosing toothpaste, while participants in the control group brushed with regular fluoridated toothpaste. Clinically, biofilm was measured using Silness & Loe Plaque Index, both at baseline and at follow up visits by two assessors who were blinded to group allocation. Adjunctly, intraoral photographs were taken for Digital Plaque Image Analysis of the remaining dental biofilm in the upper and lower anterior labial tooth surfaces, and calculated based on the area of stained pixels. Data was analyzed using SPSS version 22. Mean plaque scores between the groups were compared using independent sample t-test and p<0.05 was considered significant.RESULTS:Data of all the 40 participants were analyzed as they were no drop outs. No significant differences were found in the mean plaque scores between the two groups (p=0.059) at the end of the study. Similarly, Digital Plaque Image Analysis showed no significant difference in the mean plaque scores between the groups (p= 0.93).CONCLUSION:This study showed that there are no additional benefits of using a plaque disclosing toothpaste, in enhancing the removal of the supragingival dental biofilm during routine oral hygiene maintenance.   

Central Retinal Thickness and Visual Acuity Outcomes After Vitrectomy for Epiretinal Membrane With and Without Internal Limiting Membrane Peel

2021 ◽  
pp. 247412642110095
Author(s):  
Braden A. Burckhard ◽  
Nathan R. Mathews ◽  
Michael M. Altaweel ◽  
Jonathan S. Chang ◽  
Michael S. Ip ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Epiretinal Membrane ◽  
Statistical Difference ◽  
Retinal Thickness ◽  
Internal Limiting Membrane ◽  
Study Groups ◽  
Central Retinal Thickness ◽  
Significant Difference ◽  
The Mean

Purpose: This work compares best-corrected visual acuity (BCVA) and central retinal thickness (CRT) outcome measures following pars plana vitrectomy (PPV) with and without internal limiting membrane (ILM) peel for epiretinal membrane (ERM). Methods: A retrospective cohort study was conducted of 114 eyes of 114 patients with visually significant ERM undergoing PPV with membrane peel (PPV/MP) at a single institution. CRT measurements were collected from Heidelberg and Zeiss spectral-domain optical coherence tomography imaging units. Results compared preoperative and postoperative CRT and BCVA among patients with at least 60 days of follow-up. Results: A total of 114 eyes with ERM met the inclusion criteria. Eighty-one eyes (71%) underwent PPV/MP with ILM peel and 33 eyes (29%) underwent PPV/MP without ILM peel. There was no statistically significant difference between preoperative CRT between the 2 study groups ( P = .95). The mean follow-up time of eyes undergoing PPV/MP without ILM peel and with ILM peel was 391 days and 319 days, respectively. There was no statistical difference in the mean reduction of CRT between the 2 groups ( P = .470). Both groups had improvement of BCVA following surgery and there was no statistical difference in final logMAR visual acuity when comparing the 2 groups ( P = .738). Conclusions: There was an overall improvement of CRT and BCVA among patients undergoing PPV/MP for ERM with or without ILM peel. There was no statistically significant difference in the final BCVA or CRT between the 2 groups.

scholarly journals Evaluation of efficacy and safety of terbinafine and itraconazole in superficial mycoses: a prospective, randomized, controlled and cost-effective analysis study

2020 ◽  
Vol 9 (8) ◽  
pp. 1222
Author(s):  
D. Aruna ◽  
M. Padmaja ◽  
S. P. Vijayalakshmi
Keyword(s):  
Cost Effective ◽  
Clinical Score ◽  
Study Groups ◽  
Fungal Culture ◽  
Open Label ◽  
Superficial Mycoses ◽  
Significant Difference ◽  
The Mean

Background: Superficial mycoses are common worldwide. Dermatophytic infections can greatly affect quality of life. Several newer antimycotic agents, have been reported effective and safe. Hence this study was planned to analyse effectiveness as well as cost effectiveness of these treatments.Methods: It were a prospective, randomized, parallel, open label, comparative study. Fifty patients were included in the study and divided into 2 groups. They were randomized to receive either oral terbinafine 250 mg or itraconazole 100 mg once daily for 4 weeks. Scaling, erythema and pruritus were rated as clinical score 0 to 3: 0 - absent, 1 - mild, 2 - moderate, and 3 - severe for the above three target symptoms. Total symptom score was assessed. Pruritus was also graded on visual analogue scale (VAS). Mycological cure was assessed by skin scraping with KOH mounts and fungal culture. Clinical efficacy scoring and VAS were assessed before the study and at each follow up visit at 2 and 4 weeks. Patients were followed up for another 4 weeks after completion of the treatment.Results: There was highly significant decrease p<000.1 in the mean total symptoms scores in both the study groups from baseline. No significant difference in the mean total symptoms score was observed when compared between groups. ADRs were more in terbinafine group.Conclusions: Both terbinafine and itraconazole are effective and safe against superficial mycoses, but adverse effects are more with terbinafine. Itraconazole was found to be cost effective compared to terbinafine.

scholarly journals Comparison of the Effect of Trabeculectomy in Controlling Intraocular Pressure in Pseudo-Exfoliaiton and Primary Open Angle Glaucoma Patients

2019 ◽  
pp. 1-7
Author(s):  
S. Kavuncu ◽  
H. H. Erbil
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Study Groups ◽  
First Year ◽  
Open Angle ◽  
Significant Difference ◽  
The Mean

Objective: The aim of this study is to compare the efficacy of the trabeculectomy in controlling intraocular pressure in patients with primary open-angle and pseudo-exfoliation glaucoma. Materials and Methods: The medical data of a sum of 69 eyes of which 36 (52,2%) with primary open angle glaucoma (POAG) and 33 (47,8%) with pseudo-exfoliation (PEG), who have medically uncontrolled glaucoma and had undergone primary trabeculectomy in Göztepe Education and Research Hospital were evaluated in this retrospective study. Postoperatively, data at the first day, at the first month, and at the last examination evaluated in the study. Success of the surgery is defined as measurement of intraocular pressure under 21 mmHg with (incomplete success) or without (complete success) additional medications following the end of the first year follow-up examinations. Results: POAG group consists of 36 patients of which 16 male, 20 female and PEG group consists of 33 patients of which 21 male and 12 female. The mean age was 67.2±9.1 (42-80) years in POAG group and 70.7±6.6 (55-80) years in PEG group. There was no statistically significant difference between POAG and PEG groups in visual acuity, mean intraocular pressure, c/d ratio and the number of antiglaucomatous medications preoperatively and postoperatively (p>0.05). There was a statistically significant difference in groups between post and preoperative values in visual acuity, mean intraocular pressure, c/d ratio and the number of antiglaucomatous medications (p<0.05) Success of the trabeculectomy was 41,7% (complete success), 41,7% (incomplete success) and remaining 16,6% was unsuccessful, in POAG group and success rate in PEG group was 51.5%, 27,3% and 21,2% respectively. There was no statistically significant difference between groups (p=0.738). Conclusion: Trabeculectomy is an effective surgery in lowering intraocular pressure in both of the study groups equally.

Synbiotic supplementation is not effective on breast milk selenium concentrations and growth of exclusively breast fed infants: a pilot study

2019 ◽  
Vol 89 (1-2) ◽  
pp. 73-79 ◽  
Author(s):  
Leila Nikniaz ◽  
Reza Mahavi ◽  
Alireza Ostadrahimi ◽  
Zeinab Nikniaz ◽  
Sharare Taghipour
Keyword(s):  
Pilot Study ◽  
Breast Milk ◽  
Graphite Furnace ◽  
Controlled Trial ◽  
Study Groups ◽  
Z Score ◽  
Double Blind ◽  
Significant Difference ◽  
The Mean ◽  
Synbiotic Supplementation

Abstract. In this randomized, double-blind, placebo-controlled trial, 57 lactating mothers were randomly allocated into two groups to receive a daily supplement of synbiotic (n = 30) which contained different probiotic strains (2.0 × 108 CFU) and fructooligosaccharide (394 mg) or a placebo (n = 27) for 30 days. Dietary intake was collected from lactating women by 24-hour recall method. Breast milk selenium contents were determined by atomic absorption spectrometry with graphite furnace. Weight for age Z-score (WAZ) and Height for age Z-score (HAZ) were evaluated for infants. Data analyses were assessed using nutritionist IV, Epi Info and SPSS software and presented as mean ± sd or SEM. The total mean breast milk selenium levels were 50.1 ± 16.1 mcg L−1. At the baseline, the mean breast milk selenium concentrations in the synbiotic and placebo groups were 51.7 ± 20.2 and 48.5 ± 12.1 mcg L−1. The mean breast milk selenium levels increased and decreased in the symbiotic and placebo groups respectively, which were not significant (p > 0.05). Also, comparison of the changes in breast milk selenium concentration showed no significant difference between the two study groups after the intervention. At the baseline, the mean WAZ and HAZ of infants whose mothers’ milk selenium was more than 60 mcg/l was significantly (P < 0.05) higher than for others. In this pilot study, no significant effect was observed by synbiotic supplementation, however, for concise conclusion, more human studies with higher doses of supplements and longer duration of supplementation are needed to determine the effects of synbiotic supplementation on breast milk selenium contents and infants’ growth.

scholarly journals The Effect of Flipped Classroom by Near Peer Education (FC by NPE) on Patient Safety Knowlege Retention in Nursing and Midwifery Students: A Solomon Four-Group Design

2021 ◽  
Author(s):  
Sima poormahdi golaki ◽  
Farahnaz Kamali ◽  
Razieh Bagherzadeh ◽  
Fatemeh Hajinejad ◽  
Hakimeh Vahedparast
Keyword(s):  
Patient Safety ◽  
Flipped Classroom ◽  
Teaching Method ◽  
Controlled Trial ◽  
Study Groups ◽  
Knowledge Retention ◽  
Control Groups ◽  
Significant Difference ◽  
Safety Knowledge

Abstract Introduction: Selecting an appropriate teaching method is one of the key stages in education. This study was to the effect of FC by NPE on patient safety knowledge retention in nursing and midwifery students. Methods: This randomized controlled trial, using the Solomon design, was conducted in 2019 on an 82nursing and midwifery students enrolled from Bushehr nursing and midwifery school. The samples were then allocated to four groups via block randomization. The samples in both intervention groups studied the educational content online for two weeks and subsequently attended the FC by NPE. Both control groups merely received the conventional methods. The posttest was also taken from the four study groups immediately and two months after education. Results: The posttest mean scores of knowledge in both intervention groups was homogeneous(p=0.1) and higher than those in the control groups(p<0.05). The changes in the mean scores posttest in the intervention and follow-up it did not establish a statistically significant difference between the four study groups(p=0.130,F=1.941). Conclusion: The use of the FC by NPE could increase the knowledge mean scores, but, it failed to affect knowledge retention. Given the infancy of this pedagogical approach, further studies are needed to investigate its effects on various learning outcomes.

scholarly journals Efficacy of Combined Herbal Capsule on Sexual Function in Postmenopausal Women: A Triple-Blinded Randomized Controlled Trial

2018 ◽  
Vol 7 (3) ◽  
pp. 385-392
Author(s):  
Paria Eliasvandi ◽  
Laleh Khodaie ◽  
Sakineh Mohammad Alizadeh Charandabi ◽  
Mojgan Mirghafourvand
Keyword(s):  
Randomized Controlled Trial ◽  
Placebo Group ◽  
Sexual Function ◽  
Postmenopausal Women ◽  
Controlled Trial ◽  
Study Groups ◽  
Randomized Controlled ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Objectives: Considering the prevalence of sexual problems in postmenopausal women as well as complications of hormone therapy, the tendency to use complementary medicine has increased. The present study was conducted to evaluate the efficacy of combined herbal drug on the sexual function of postmenopausal women. Materials and Methods: The present triple-blinded randomized controlled trial was done on 64 Iranian women in 2017. The women were randomly allocated to 2 groups of intervention (combined herbal capsules users) and control (placebo users). Herbal capsules contained carnation, Anise, Anison, violets, Terminalia chebula, fresh green raisins, Senna leaves, Tangerine and Golqand. Participants in both groups took 2 capsules twice a day (before lunch and before dinner) for 4 weeks. The Female Sexual Function Index (FSFI) was filled out before the intervention and 4 weeks after the intervention. Results: No statistically significant difference was observed between the study groups in terms of socio-demographic properties, the total mean score of sexual function and its sub-domains before the intervention. Four weeks after the intervention, the total mean (SD) sexual function score was 26.99 (5.31) in the combined herbal capsule group and it was 18.35 (4.51) in the placebo group, so it was significantly higher in the combined herbal capsule group compared to the placebo group (adjusted mean difference=8.70; 95% CI=6.58-10.82). Moreover, there was a significant difference in the mean score of desire, arousal, lubrication, orgasm, satisfaction, and pain subscales between study groups after the intervention. Conclusions: The results of the study show that taking combined herbal capsules improved sexual function in postmenopausal women. However, further studies are necessary to decide on its use as an alternative medication for the improvement of sexual function.

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