scholarly journals The Application of Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography in Macular Diseases

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Jing Wang ◽  
Lian-Rong Yin
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Spectral Domain ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Diagnosis And Prognosis ◽  
Macular Diseases ◽  
Sd Oct

The choroid plays an essential role in the pathogenesis of various posterior segment diseases. However, traditional imaging methods still have limited cross-sectional observation of choroid. Enhanced depth imaging in spectral-domain optical coherence tomography (EDI SD-OCT) uses a closer scanning position to the eye to create an inverted SD-OCT image with the advantage of better depth sensitivity, which can observe choroidal structure and measure choroidal thickness (CT) accurately. At present, more and more choroidal thickness measurements have been made in normal and pathologic states, in order to understand the pathogenesis and differential diagnosis and prognosis of various diseases, especially for macular lesions. This paper would review relevant original literatures published from January 1, 2008, to February 1, 2020, to evaluate the relationship between the changes of CT with EDI SD-OCT and macular diseases.

Measurement of Subfoveal Choroidal Thickness in Pseudoexfoliation Syndrome Using Enhanced Depth Imaging Optical Coherence Tomography

2015 ◽  
Vol 233 (3-4) ◽  
pp. 204-208 ◽  
Author(s):  
Ece Turan-Vural ◽  
Nursal Yenerel ◽  
Murat Okutucu ◽  
Elvin Yildiz ◽  
Nejla Dikmen
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Subfoveal Choroidal Thickness ◽  
Imaging Optical Coherence Tomography

Background/Aim: Pseudoexfoliation (PSX) syndrome is associated with blood flow disturbances; however, its exact effect on choroidal blood flow and thickness remains to be elucidated. This study compared subfoveal choroidal thickness in normal eyes and in eyes with PSX using enhanced depth imaging optical coherence tomography (EDI-OCT). Methods: This prospective, cross-sectional study included 35 eyes of 35 patients (20 males, 15 females) with unilateral or bilateral PSX and 26 eyes of 26 healthy volunteers (13 males, 13 females). Besides a comprehensive ocular and physical examination, all subjects underwent EDI-OCT examination using an Optovue RTVue OCT device (Optovue Inc., Fremont, Calif., USA). Results: The mean choroidal thickness (CT) and ocular perfusion pressure (OPP) were lower in the PSX group than in the healthy controls (249.4 ± 46.3 vs. 282.5 ± 55.8 µm, p = 0.014 and 40.7 ± 5.8 vs. 44.3 ± 4.3 mm Hg, p = 0.007, respectively). In addition, both systolic blood pressure and diastolic blood pressure measurements were lower among the PSX patients. However, no correlation was found between CT and OPP. Conclusion: The findings of this study suggest that PSX is associated with an overall thinning of the subfoveal choroid and a significant decrease in OPP. Future studies are warranted to further examine these relations.

scholarly journals Management of Patients with Graves’ Disease and Orbital Involvement: Role of Spectral Domain Optical Coherence Tomography

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Alice Bruscolini ◽  
Maurizio La Cava ◽  
Magda Gharbiya ◽  
Marta Sacchetti ◽  
Lucia Restivo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Spectral Domain ◽  
Enhanced Depth Imaging ◽  
Clinical Activity ◽  
Graves Disease ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Orbital Involvement

Purpose. To investigate the role of choroidal thickness evaluation with spectral domain optical coherence tomography (SDOCT) and enhanced depth imaging (EDI) technique in the management of patients with Graves’ disease and orbitopathy (GO). Methods. Thirty-six eyes of 18 patients with GO and 36 eyes of 18 age-matched control subjects were included in this retrospective observational study. All the subjects underwent a complete ophthalmological evaluation, including clinical activity score (CAS) and exophthalmometry. The SDOCT images of the choroid were obtained by EDI modality. Results. Choroidal thickness was significantly increased in GO than in control eyes (p<0.01). A significant correlation was found between choroidal thickness and CAS, proptosis, and the duration of disease (p<0.05). Conclusion. This study shows that choroidal thickness, evaluated with EDI-OCT, is significantly increased in patients with GO and correlates with the activity of the disease, proptosis, and duration of the disease. The choroidal thickening may reflect the ocular hemodynamic changes, and enhanced depth imaging optical coherence tomography may be a useful tool for the evaluation of orbital congestion and management of patients with Graves’ disease and orbital involvement.

scholarly journals Macular and choroidal thicknesses in a healthy Hispanic population evaluated by high-definition spectral-domain optical coherence tomography (SD-OCT)

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Diana A. Cortés ◽  
Daniela Roca ◽  
Pedro Iván Navarro ◽  
Francisco J. Rodríguez
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Correlation Study ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Hispanic Population ◽  
High Definition ◽  
Cross Sectional ◽  
Significant Difference ◽  
Sd Oct

Abstract Purpose To report normal values of macular and choroidal thickness obtained from a healthy Hispanic population using Optovue (Optovue Inc, Freemont CA, USA) spectral domain optical coherence tomography (SD-OCT). Design Observational, cross-sectional, correlation study. Methods A total of 290 eyes (145 healthy subjects) were included; 69% of subjects were female. The median age was 39 ± 29 years (IQR), with a range between 18 and 89 years. The study sample was stratified into three age groups: Group 1, 18–40 years (50.3%), Group 2, 41–60 years (30.7%), and Group 3, older than 61 years (19%). Central macular, perifoveal (inner quadrants), and parafoveal (outer quadrants) thicknesses were estimated. In addition, central and peripheral choroidal thicknesses were estimated. Data analysis was performed to calculate the standardized mean difference according to the variance (Student’s t-test) and its differences with Epidat 4.1. Results Median macular central thickness was 250 ±30 µm (IQR) with Optovue. Median central choroidal thickness was 263 ± 48 µm (IQR). Median central choroidal thickness was greater than mean peripheral thickness. Macular evaluation showed a statistically significant difference in central, perifoveal, and parafoveal thicknesses, with lower values being recorded for the study sample compared with the manufacturer’s data. Conclusions SD-OCT has become a useful tool to obtain high-resolution images of the macula and choroid. This method allows precise assessment of the retinal and choroidal layers to diagnose and follow up posterior segment diseases. We are reporting normal cut-off values of macular and choroidal thicknesses in healthy Hispanic subjects evaluated with Optovue SD-OCT as new diagnostic normal parameters for research and clinical activities.

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