scholarly journals A Multichannel Biomedical Named Entity Recognition Model Based on Multitask Learning and Contextualized Word Representations

2020 ◽  
Vol 2020 ◽  
pp. 1-13 ◽  
Author(s):  
Hao Wei ◽  
Mingyuan Gao ◽  
Ai Zhou ◽  
Fei Chen ◽  
Wen Qu ◽  
...  

As the biomedical literature increases exponentially, biomedical named entity recognition (BNER) has become an important task in biomedical information extraction. In the previous studies based on deep learning, pretrained word embedding becomes an indispensable part of the neural network models, effectively improving their performance. However, the biomedical literature typically contains numerous polysemous and ambiguous words. Using fixed pretrained word representations is not appropriate. Therefore, this paper adopts the pretrained embeddings from language models (ELMo) to generate dynamic word embeddings according to context. In addition, in order to avoid the problem of insufficient training data in specific fields and introduce richer input representations, we propose a multitask learning multichannel bidirectional gated recurrent unit (BiGRU) model. Multiple feature representations (e.g., word-level, contextualized word-level, character-level) are, respectively, or collectively fed into the different channels. Manual participation and feature engineering can be avoided through automatic capturing features in BiGRU. In merge layer, multiple methods are designed to integrate the outputs of multichannel BiGRU. We combine BiGRU with the conditional random field (CRF) to address labels’ dependence in sequence labeling. Moreover, we introduce the auxiliary corpora with same entity types for the main corpora to be evaluated in multitask learning framework, then train our model on these separate corpora and share parameters with each other. Our model obtains promising results on the JNLPBA and NCBI-disease corpora, with F1-scores of 76.0% and 88.7%, respectively. The latter achieves the best performance among reported existing feature-based models.

2020 ◽  
Author(s):  
Usman Naseem ◽  
Matloob Khushi ◽  
Vinay Reddy ◽  
Sakthivel Rajendran ◽  
Imran Razzak ◽  
...  

Abstract Background: In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER research is challenging as NER in the biomedical domain are: (i) often restricted due to limited amount of training data, (ii) an entity can refer to multiple types and concepts depending on its context and, (iii) heavy reliance on acronyms that are sub-domain specific. Existing BioNER approaches often neglect these issues and directly adopt the state-of-the-art (SOTA) models trained in general corpora which often yields unsatisfactory results. Results: We propose biomedical ALBERT (A Lite Bidirectional Encoder Representations from Transformers for Biomedical Text Mining) - bioALBERT - an effective domain-specific pre-trained language model trained on huge biomedical corpus designed to capture biomedical context-dependent NER. We adopted self-supervised loss function used in ALBERT that targets on modelling inter-sentence coherence to better learn context-dependent representations and incorporated parameter reduction strategies to minimise memory usage and enhance the training time in BioNER. In our experiments, BioALBERT outperformed comparative SOTA BioNER models on eight biomedical NER benchmark datasets with four different entity types. The performance is increased for; (i) disease type corpora by 7.47% (NCBI-disease) and 10.63% (BC5CDR-disease); (ii) drug-chem type corpora by 4.61% (BC5CDR-Chem) and 3.89 (BC4CHEMD); (iii) gene-protein type corpora by 12.25% (BC2GM) and 6.42% (JNLPBA); and (iv) Species type corpora by 6.19% (LINNAEUS) and 23.71% (Species-800) is observed which leads to a state-of-the-art results. Conclusions: The performance of proposed model on four different biomedical entity types shows that our model is robust and generalizable in recognizing biomedical entities in text. We trained four different variants of BioALBERT models which are available for the research community to be used in future research.


2019 ◽  
Vol 9 (18) ◽  
pp. 3658 ◽  
Author(s):  
Jianliang Yang ◽  
Yuenan Liu ◽  
Minghui Qian ◽  
Chenghua Guan ◽  
Xiangfei Yuan

Clinical named entity recognition is an essential task for humans to analyze large-scale electronic medical records efficiently. Traditional rule-based solutions need considerable human effort to build rules and dictionaries; machine learning-based solutions need laborious feature engineering. For the moment, deep learning solutions like Long Short-term Memory with Conditional Random Field (LSTM–CRF) achieved considerable performance in many datasets. In this paper, we developed a multitask attention-based bidirectional LSTM–CRF (Att-biLSTM–CRF) model with pretrained Embeddings from Language Models (ELMo) in order to achieve better performance. In the multitask system, an additional task named entity discovery was designed to enhance the model’s perception of unknown entities. Experiments were conducted on the 2010 Informatics for Integrating Biology & the Bedside/Veterans Affairs (I2B2/VA) dataset. Experimental results show that our model outperforms the state-of-the-art solution both on the single model and ensemble model. Our work proposes an approach to improve the recall in the clinical named entity recognition task based on the multitask mechanism.


2021 ◽  
Vol 7 ◽  
pp. e384
Author(s):  
Rigo E. Ramos-Vargas ◽  
Israel Román-Godínez ◽  
Sulema Torres-Ramos

Increased interest in the use of word embeddings, such as word representation, for biomedical named entity recognition (BioNER) has highlighted the need for evaluations that aid in selecting the best word embedding to be used. One common criterion for selecting a word embedding is the type of source from which it is generated; that is, general (e.g., Wikipedia, Common Crawl), or specific (e.g., biomedical literature). Using specific word embeddings for the BioNER task has been strongly recommended, considering that they have provided better coverage and semantic relationships among medical entities. To the best of our knowledge, most studies have focused on improving BioNER task performance by, on the one hand, combining several features extracted from the text (for instance, linguistic, morphological, character embedding, and word embedding itself) and, on the other, testing several state-of-the-art named entity recognition algorithms. The latter, however, do not pay great attention to the influence of the word embeddings, and do not facilitate observing their real impact on the BioNER task. For this reason, the present study evaluates three well-known NER algorithms (CRF, BiLSTM, BiLSTM-CRF) with respect to two corpora (DrugBank and MedLine) using two classic word embeddings, GloVe Common Crawl (of the general type) and Pyysalo PM + PMC (specific), as unique features. Furthermore, three contextualized word embeddings (ELMo, Pooled Flair, and Transformer) are compared in their general and specific versions. The aim is to determine whether general embeddings can perform better than specialized ones on the BioNER task. To this end, four experiments were designed. In the first, we set out to identify the combination of classic word embedding, NER algorithm, and corpus that results in the best performance. The second evaluated the effect of the size of the corpus on performance. The third assessed the semantic cohesiveness of the classic word embeddings and their correlation with respect to several gold standards; while the fourth evaluates the performance of general and specific contextualized word embeddings on the BioNER task. Results show that the classic general word embedding GloVe Common Crawl performed better in the DrugBank corpus, despite having less word coverage and a lower internal semantic relationship than the classic specific word embedding, Pyysalo PM + PMC; while in the contextualized word embeddings the best results are presented in the specific ones. We conclude, therefore, when using classic word embeddings as features on the BioNER task, the general ones could be considered a good option. On the other hand, when using contextualized word embeddings, the specific ones are the best option.


Information ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 82
Author(s):  
SaiKiranmai Gorla ◽  
Lalita Bhanu Murthy Neti ◽  
Aruna Malapati

Named entity recognition (NER) is a fundamental step for many natural language processing tasks and hence enhancing the performance of NER models is always appreciated. With limited resources being available, NER for South-East Asian languages like Telugu is quite a challenging problem. This paper attempts to improve the NER performance for Telugu using gazetteer-related features, which are automatically generated using Wikipedia pages. We make use of these gazetteer features along with other well-known features like contextual, word-level, and corpus features to build NER models. NER models are developed using three well-known classifiers—conditional random field (CRF), support vector machine (SVM), and margin infused relaxed algorithms (MIRA). The gazetteer features are shown to improve the performance, and theMIRA-based NER model fared better than its counterparts SVM and CRF.


2021 ◽  
Vol 11 (19) ◽  
pp. 9038
Author(s):  
Wazir Ali ◽  
Jay Kumar ◽  
Zenglin Xu ◽  
Rajesh Kumar ◽  
Yazhou Ren

Named entity recognition (NER) is a fundamental task in many natural language processing (NLP) applications, such as text summarization and semantic information retrieval. Recently, deep neural networks (NNs) with the attention mechanism yield excellent performance in NER by taking advantage of character-level and word-level representation learning. In this paper, we propose a deep context-aware bidirectional long short-term memory (CaBiLSTM) model for the Sindhi NER task. The model relies upon contextual representation learning (CRL), bidirectional encoder, self-attention, and sequential conditional random field (CRF). The CaBiLSTM model incorporates task-oriented CRL based on joint character-level and word-level representations. It takes character-level input to learn the character representations. Afterwards, the character representations are transformed into word features, and the bidirectional encoder learns the word representations. The output of the final encoder is fed into the self-attention through a hidden layer before decoding. Finally, we employ the CRF for the prediction of label sequences. The baselines and the proposed CaBiLSTM model are compared by exploiting pretrained Sindhi GloVe (SdGloVe), Sindhi fastText (SdfastText), task-oriented, and CRL-based word representations on the recently proposed SiNER dataset. Our proposed CaBiLSTM model achieved a high F1-score of 91.25% on the SiNER dataset with CRL without relying on additional handmade features, such as hand-crafted rules, gazetteers, or dictionaries.


2020 ◽  
Vol 34 (05) ◽  
pp. 7415-7423
Author(s):  
M Saiful Bari ◽  
Shafiq Joty ◽  
Prathyusha Jwalapuram

Recently, neural methods have achieved state-of-the-art (SOTA) results in Named Entity Recognition (NER) tasks for many languages without the need for manually crafted features. However, these models still require manually annotated training data, which is not available for many languages. In this paper, we propose an unsupervised cross-lingual NER model that can transfer NER knowledge from one language to another in a completely unsupervised way without relying on any bilingual dictionary or parallel data. Our model achieves this through word-level adversarial learning and augmented fine-tuning with parameter sharing and feature augmentation. Experiments on five different languages demonstrate the effectiveness of our approach, outperforming existing models by a good margin and setting a new SOTA for each language pair.


2020 ◽  
Author(s):  
YUANHE TIAN ◽  
Wang Shen ◽  
Yan Song ◽  
Fei Xia ◽  
Min He ◽  
...  

Abstract Background Biomedical named entity recognition (BioNER) is an important task for understanding biomedical texts. The task can be challenging due to the lack of large-scale labeled training data and domain knowledge. Previous studies have shown that syntactic information can be useful for named entity recognition; however, most of them fail to weigh that information with respect to its contribution as they treat the syntactic information as gold reference. Results In this paper, we propose BioKMNER, a BioNER model for biomedical texts with key-value memory networks to incorporate syntactic information, which is extracted from syntactic structures automatically generated by existing toolkits. Our approach outperforms baselines without memories and achieves new state-of-the-art results on on four biomedical datasets compared with previous studies, i.e., 85.67% on BC2GM, 94.22% on BC5CDR-chemical, 90.11% on NCBI-diease, and 76.33% on Species-800. Conclusion Experimental results on four benchmark datasets demonstrate the effectiveness of our method, where the state-of-the-art performance is achieved on all of them.


Information ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 248 ◽  
Author(s):  
Sumam Francis ◽  
Jordy Van Landeghem ◽  
Marie-Francine Moens

Recent deep learning approaches have shown promising results for named entity recognition (NER). A reasonable assumption for training robust deep learning models is that a sufficient amount of high-quality annotated training data is available. However, in many real-world scenarios, labeled training data is scarcely present. In this paper we consider two use cases: generic entity extraction from financial and from biomedical documents. First, we have developed a character based model for NER in financial documents and a word and character based model with attention for NER in biomedical documents. Further, we have analyzed how transfer learning addresses the problem of limited training data in a target domain. We demonstrate through experiments that NER models trained on labeled data from a source domain can be used as base models and then be fine-tuned with few labeled data for recognition of different named entity classes in a target domain. We also witness an interest in language models to improve NER as a way of coping with limited labeled data. The current most successful language model is BERT. Because of its success in state-of-the-art models we integrate representations based on BERT in our biomedical NER model along with word and character information. The results are compared with a state-of-the-art model applied on a benchmarking biomedical corpus.


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