scholarly journals Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Jerald Pelayo ◽  
Gabriella Pugliese ◽  
Grace Salacup ◽  
Eduardo Quintero ◽  
Adeeb Khalifeh ◽  
...  

The rapidly expanding cases of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed vulnerable populations, including pregnant women to an unprecedented public health crisis. Recent data show that pregnancy in COVID-19 patients is associated with increased hospitalization, admission of the intensive care unit, and intubation. However, very few resources exist to guide the multidisciplinary team in managing critically ill pregnant women with COVID-19. We report our experience with managing a morbidly obese pregnant woman at 36 weeks’ gestation with history of asthma and malignancy who presented with persistent respiratory symptoms at an outside hospital after being tested positive for SARS-CoV-2 polymerase chain reaction (PCR). Early in the course of the hospitalization, patient received remdesivir, convalescent plasma, bronchodilator, systemic steroids, and IV heparin for COVID-19 and concomitant asthma exacerbation and pulmonary embolism. Due to increasing oxygen requirements, she was eventually intubated and transferred to our institution for higher level of care. Respiratory acidosis, severe hypoxemia, and vent asynchrony were managed with vent setting adjustment and paralytics. After 12 hours from spontaneous rupture of her membranes and with stabilization of maternal status, patient underwent a term cesarean delivery for nonreassuring fetal heart tracing. The neonate was discharged on the 2nd day of life, while the patient was extubated on the 6th postpartum day and was discharged to acute inpatient rehabilitation facility on the 19th hospital day. This report highlights the disease progression of COVID-19 in a pregnant woman, the clinical challenges in the critical care aspect of patient management, and the proposed multidisciplinary strategies utilizing an algorithmic approach to optimize maternal and neonatal outcomes.

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Zhenyu Zhang ◽  
Jiangyan Lou

Prostaglandin E2is widely used in obstetrics and is thought to be relatively safe for cervical ripening and induction of labour. Here we present a case in which acute hemoperitoneum was observed after administration of prostaglandin E2in a pregnant woman. The patient had a history of endometriosis, and a severe pelvic adhesion (ASRM stage IV) was found during her last laparoscopic surgery 3 years previously. In cases with endometriosis, use of prostaglandin E2for induction of labour in pregnant women must be done cautiously.


2019 ◽  
Vol 11 (2) ◽  
pp. 17-28
Author(s):  
Eka Ratna Sari ◽  
Lusi Andriani ◽  
PS. Kurniawati

Anemia in pregnancy is a condition of pregnant woman with hemoglobin (Hb) <11 gr% in the first and third trimesters while in the second trimester hemoglobin level <10,5 gr%. World Health Organization (WHO) in 2012, reported that the prevalence of anemia in pregnant women in the world ranges an average of 14%, in industrialized countries 56% and in developing countries between 35% -75%. This study aims to determined the factors of the occurrence of anemia in third trimester pregnant women in Kampung Melayu sub-district Bengkulu City 2017. This research uses Analytical Survey design with Cross Sectional Approach. Population in this research is third trimester pregnant woman in Kampung Melayu sub-district as many as 106 people, using sample total sampling technique. The analysis used Chi square test with significance level p <0,05.The results of this study indicate that there is a relationship between adherence of Fe (p = 0,000) and knowledge (p = 0,000) with anemia occurrence in third trimester pregnant women, no relationship between age (p = 0,346), parity (p = 0,949) , Education (p = 0.198), occupation (p = 1,000) with anemia and the most dominant factor with anemia was the consumption of Fe tablet (OR = 78,803). Health workers are expected to provide routine counseling on the causes, symptoms, and effects of anemia for pregnant women and screening anemia by checking Hb at least twice during pregnancy.


2012 ◽  
Vol 8 (3) ◽  
pp. 321-324
Author(s):  
S R Tamrakur ◽  
C D Chawla

Background Cervical incompetence is one of the main contributors to repeated pregnancy loss, accounting for approximately 25% of the cases. Typically it results in progressive cervical dilatation, leading to a painless second- or early-third-trimester abortion. Objectives The main objective of the study was to explore the benefit from cervical cerclage in pregnant women with anatomical cervical incompetence Methods In a review of the operation and labour registers from January 2006 till January 2010, a total of 38 cervical cerclage procedures were performed at Dhulikhel Hospital (DH). In the study caste, parity, gestational age, diagnostic criteria, postoperative complications and pregnancy outcomes of the cases were analyzed. Results Two of the 38 cases didn’t come for delivery at Dhulikhel Hospital (Kathmandu University Teaching Hospital). Four women haven’t delivered at the time of data analysis. So pregnancy outcomes were analyzed among 32 cases while rests of the variables were analyzed among 38 cases. Of them 18 cases (47%) were Brahmin, 22 cases (58%) were between 20-25 years old and 32 cases (84%) were from Kavre district.  All cases were booked cases (they had antenatal care in the hospital) and 14 patients (37%) were third gravida. Most cases had 2 to 4 antenatal visits prior to suturing. Two cases were diagnosed with a bicornuate uterus. 21 cases (55%) had a previous history of at least one dilatation and evacuation.  33 cases (87%) were diagnosed with cervical incompetence clinically and confirmed by ultrasound. The remaining 13% were assessed, in the absence of a history of mid-trimester abortion, of having a high suspicion of cervical incompetence after mid-trimester scan with measurement of cervical length. In 18 cases (47%), cervical cerclage were done at 15 to 20 weeks of gestation. The postoperative period was uneventful in all 38 cases.  All cases (32) delivered in DH were assisted by consultant obstetricians. 19 out 32 cases (59%) were delivered vaginally at term. Conclusions38 cases were included in the study. Pregnancy outcomes were analyzed among 32 cases while rests of the variables were analyzed among 38 cases. 31 out 32 cases were delivered with good foetal weight. It clearly shows pregnant women with anatomical cervical incompetence were benefitted from cervical cerclage. The authors recommend an early trans vaginal scan in any patient with a history of mid trimester abortion or preterm labour. The cervical cerclage procedure therefore should be available more widely to benefit those patients with proven or strongly suspected cervical incompetence.DOI: http://dx.doi.org/10.3126/kumj.v8i3.6222 Kathmandu Univ Med J 2010;8(3):321-24 


2008 ◽  
Vol 10 (Number 1) ◽  
pp. 10-15
Author(s):  
D K Sunyal ◽  
Md. R Amin ◽  
MH Md. R ◽  
GM Kibria ◽  
G M Molla ◽  
...  

In the present study the partial pressure of carbon dioxide in arterial blood (PaC0:1 and respiratory rate (RR) were studied in pregnant and non-pregnant women in Dhaka city. Far this purpose a total 32 women for PaCO)and 100 women for RR with age ranging front 25 ...ears le 35 years without any recent history of respiratory diseases were selected. Normal pregnant women were taken as e.yperimental group and healthy nor-pregnant ...omen as return!. Data was collected during first trimester. second trimester and third trimester in pregnant women and also nompregnant women. The PaCOrwas determined by using 'EASY BLOOD GAS .0TO INALMER" and RR was recorded. The PaCO, and RR during different trimesters of pregnant .rumen were compared with that of non-pregnant 11.1101. Statistical analysis was drum with .tudents '1' rest. The PeCOr was significantly lower in first trimester, second trimester and third (rimester of pregnant women than that of non-pregnant women. Similarly, RR was significantly higher in first trimester. second trimester and third trimester of pregnant women than that of nonpregnant women. Again RR was significantly higher in third trimester than in first trimester and second trimester of pregnant women. There were no statistically significant difference of PaCO, among first trimester. second trimester and third trimester of pregnant women. Similarly, there were no statistically significant difference of RR between first trimester and second trimester of pregnant women. It may be concluded from the study that the progressively decreased PaCO• and increased RR throughout Me pregnancy were most likely MP be related to the effect of progesterone-induced hyperventilation. Hypermfilation in pregnancy is due to hypersensitivity of respiratory centre. Due to hyperventilation there is expel out of CO, miming decrease in PaC0r and increase in RR during pregnancy.


2018 ◽  
Vol 8 (2) ◽  
pp. 46
Author(s):  
Ni Made Rai Widiastuti ◽  
NI KADEK PEMUDI MAHAYANI ◽  
NI KADEK PEMUDI MAHAYANI

<p><strong>Abstract: Suvey Plan of Use of Contraceptive Method After Delivery in Pregnant Woman of Third Semester</strong><strong>. </strong><em>This research is aimed to know the plan of contraseption  after delivery in third trimester pregnant woman at Puskesmas Pembantu Dauh Puri. Cross sectional study was performed on third trimester pregnant women with total number of 63 people and wasconsecutive sampling. Data was collected by interview using structured questionnaire. The results showed that most of 33 respondents (52.4%) did not have plan for the use of postnatal constraseption after delivery</em>.<strong></strong></p><p><em> </em></p><p><strong>Abstrak: Survei Rencana Pemakaian Metode K</strong><strong>B</strong><strong> Pasca Persalinan</strong><strong> </strong><strong>Pada Ibu Hamil Trimester III. </strong>Penelitian ini bertujuan untuk Mengetahui rencana pemakaian KB pasca persalinan pada ibu hamil trimester III di Puskesmas Pembantu Dauh Puri. Penelitian <em>cross sectional</em> dilakukan pada ibu hamil trimester III dengan jumlah sebanyak 63 orang dan dipilih secara <em>consecutive sampling</em>. Data dikumpulkan dengan wawancara menggunakan kuesioner terstruktur. Hasil penelitian menunjukkan sebagian besar yaitu sebanyak 33 responden (52,4%) tidak mempunyai rencana pemakaian metode KB pasca persalinan. </p>


2021 ◽  
Vol 17 ◽  
Author(s):  
Fatemeh Azarkish ◽  
Roksana Janghorban

Background: Pregnant women are a vulnerable group in viral outbreaks, especially in the COVID-19 pandemic. Objective: The aim of this review was to identify maternal and neonatal outcomes in available articles on pregnancies affected by COVID-19. Methods: The articles that had assessed outcomes of pregnancy and perinatal of women with COVID-19 between Oct 2019 and Aug 2020 without language limitation were considered. We searched databases, selected relevant studies and extracted data regarding maternal and neonatal outcomes from each article. Results: Data of 11078 pregnant women with COVID-19 of 23 countries were assessed from 77 articles between December 8, 2019 and Aug 18, 2020. Most pregnant women reported in their third trimester, out of which 6229 (56.22%) cases were symptomatic at the time of admission. Common onset symptoms, abnormal laboratory findings, and chest computed tomography pattern were cough (40.88%), lymphocytopenia (43.38%), and multiple ground-glass opacities (4.42%), respectively. 51.37% of all deliveries were done through cesarean section. 158 maternal mortality and 4.2 % ICU admission were reported. Vertical transmission was not reported, but its possibility was suggested in thirty-two neonates. Ten neonatal deaths, thirteen stillbirths, and nineteen abortions were reported. 60% of newborns were not breastfed. Conclusion: This review showed fewer adverse maternal and neonatal outcomes in pregnant women with COVID-19 in comparison with previous coronavirus outbreak infection in pregnancy. Limited data are available regarding the possibility of virus transmission in utero, during vaginal childbirth and breastfeeding. The effect of COVID-19 on the first and second trimesters and ongoing pregnancy outcomes in infected mothers is still questionable.


2015 ◽  
Vol 52 (2) ◽  
pp. 100-104 ◽  
Author(s):  
Valesca DALL'ALBA ◽  
Sidia Maria CALLEGARI-JACQUES ◽  
Cláudio KRAHE ◽  
Juliana Paula BRUCH ◽  
Bruna Cherubini ALVES ◽  
...  

Background Heartburn and regurgitation frequently occur in the third trimester of pregnancy, but their impact on quality of life has not been thoroughly investigated. Objective To measure health-related quality of life of third-trimester pregnant women with heartburn and regurgitation. Methods Data on obstetric history, heartburn and regurgitation frequency and intensity, history of heartburn and regurgitation and health-related quality of life were collected of 82 third-trimester pregnant women. Results Sixty-two (76%) women had heartburn, and 58 (71%), regurgitation; 20 were asymptomatic. Mean gestational age was 33.8±3.7 weeks; 35 (43%) women had a family history of heartburn and/or regurgitation, and 57 (70%) were asymptomatic before pregnancy. The following quality of life concepts were significantly reduced: physical problems and social functioning for heartburn; physical problems and emotional functioning for regurgitation. There was agreement between heartburn in present and previous pregnancies. Conclusion Heartburn and/or regurgitation affected health-related quality of life of third trimester pregnant women


2019 ◽  
Author(s):  
Brianna C Delker ◽  
Amanda Van Scoyoc ◽  
Laura K. Noll

Punitive attitudes and consequences (e.g., incarceration) for prenatal illicit drug use persist in the United States despite evidence that these policies are ineffective and even harmful to women and children. For instance, the threat of these consequences can deter women from seeking healthcare, prenatal care, and drug treatment. Punitive responses may persist due to pejorative public perceptions of pregnant women who use illicit drugs. Although there is evidence that contextual information about prenatal drug use (e.g., drug type) can change such perceptions, other contextual influences are unknown. This experimental study tested whether receiving contextual information about a pregnant woman who uses drugs (specifically, her childhood trauma history) reduces punitive and increases supportive attitudes toward the woman. In a vignette-based 2(pregnancy status: pregnant/not pregnant) x 2(history of childhood trauma: interpersonal/non-interpersonal) between-subjects design, young adult university participants (N=461) were randomly assigned to read a vignette about a woman who uses methamphetamine. Punitive attitudes were significantly reduced by information that the pregnant woman had a history of childhood trauma, especially interpersonal (versus non-interpersonal) trauma (ηp2=.115). Supportive attitudes were not impacted (ηp2=.005). Information about the pregnant woman’s trauma history predicted less agreement with incarcerating her, only indirectly, through less punitive attitudes (R2=.21). Reductions in punitive attitudes were on the order of 1.5-2 points on 5-point self-report scales and controlled for participant gender and political conservatism. Results have practical implications for interdisciplinary work aimed at unlocking greater support for policies that help pregnant women make safe, informed decisions with dignity and access to healthcare.


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