scholarly journals Parkinson’s Disease Gravity Index: A Method by means of Optimal Scaling

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Marcos Serrano-Dueñas ◽  
Luis Masabanda ◽  
Maria-Rosario Luquin

Objective. This study has been designed with the aim of using optimal scaling to perform the allocation of scores and to be able to construct an indicator of the Parkinson’s Disease Gravity Index. Scores were assigned to interrelated dimensions that share information about the patient’s situation, to have an objective, holistic tool which integrates scores so that doctors can have a comprehensive idea of the patient’s situation. Patients and Methods. 120 consecutive patients with Parkinson’s diagnosis were chosen according to the United Kingdom Parkinson’s Disease Society Brain Bank criteria. Subsequently, all the chosen dimensions were transformed into interval variables for which the formula proposed by Sturges was used. Once the dimensions were transformed into interval variables, optimal scaling was carried out. Subsequently, the following attributes were analyzed: quality and acceptability of the data; reliability: internal consistency, reliability index, Cronbach’s alpha, and standard error of measurement; finally, validity: convergent validity and validity for known groups. Results. There were no missing data. An appropriate Cronbach’s alpha value of 0.71 was gathered, and all items were found to be pertinent to the scale. The item homogeneity index was 0.36. Precision evaluated with the standard error of measurement was 7.8. The Parkinson’s Disease Gravity Index discriminant validity (validity for known groups), assessed among the different stages of Hoehn and Yahr scale by the Kruskal–Wallis test, showed major significance (X2 = 32.7, p ≤ 0.001 ). Conclusions. The Parkinson’s Disease Gravity Index has shown adequate metric properties.

2020 ◽  
Author(s):  
Thomas JB Kropmans ◽  
Eirik Søfteland ◽  
Anneke Wijnalda ◽  
Marie Thoresen ◽  
Magnus Hultin ◽  
...  

Abstract BackgroundUntil 2008, Objective Structured Clinical Examinations (OSCE) were well researched, laborious and costly paper based method of exam delivery restricting international comparison. Cross-institutional comparison of OSCE Quality Assurance in Europe has never been done and due to wide spread electronic assessment analysis is now available.MethodsTwenty educational institutions across Europe using an electronic OSCE Management Information System where invited of which 8 confirmed to join a mutual comparison of Quality Assurance outcome. Two theories evaluate the quality of the observed test scores, the Classical psychometric theory (Cronbach’s alpha) and the Generalizability theory. Outcomes for both were compared for all universities including the Standard Error of Measurement (SEM) as well as cut-scores, Pass/Fail score and Global Rating Scores, Cronbach’s Alpha and related SEM (68% and 95% CI) and G-theory Coefficients with related absolute and relative SEM (68% and 95% CI). ResultsOutcomes differ between participating universities and observed marks contradict global rating of fail, borderline and excellent performance. G-theory coefficients and Standard Error of Measurement were lower and smaller compared to the classical approach using Cronbach’s Alpha as measure of reliability. The Classical psychometric based SEM varies from 2.8% to 11.2% respectively whereas the 95% CI equivalent varied from 9.2% up to 22% (on a 0 - 100% scale). The relative SEM from G-theory analysis varied from 3.1% to 7.0% for criterion-referenced marks, and the absolute SEM for norm-referenced marks varied from 3.8% to 7.8% respectively. The 95% CI around the relative and absolute SEMs values varied from 7.3% to 15.3%. More students failed the examination if the 95% CI is applied to the observed scores.ConclusionTo protect society and to improve educational decision making, the Standard Error of Measurement and associated confidence intervals needs to be embedded in EU assessment strategies to rule out ‘false positive Pass decisions’.


2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Maryam Mehdizadeh ◽  
Seyed-Mohammad Fereshtehnejad ◽  
Sepide Goudarzi ◽  
Ainaz Moshtagh ◽  
Farzaneh Dehghanian Nasrabadi ◽  
...  

Purpose. Pain is one of the nonmotor symptoms of Parkinson’s disease (PD) that, in order to be better managed, requires to be evaluated. Evaluations are done using pain assessment scales such as the Short-Form McGill Pain Questionnaire-2 (SF-MPQ-2). The goal of this study was to assess the psychometric properties of SF-MPQ-2 to measure pain in people with PD. Methods. Four hundred and twenty-eight PD patients with a mean (SD) age of 60.11 (11.44) years were included. Accessibility was measured through floor and ceiling effects. Dimensionality was estimated by exploratory factor analysis. The association between SF-MPQ-2 and other scales such as Neuropathic Pain Symptom Inventory, Douleur Neuropathic 4, Brief Pain Inventory, King’s Pain Parkinson’s Disease Scale, and Visual Analog Scale-Pain was considered to calculate convergent validity. Internal consistency and test-retest reliability were assessed by Cronbach’s alpha and intraclass correlation coefficient (ICC), respectively. Results. A noticeable floor effect was found. Dimensionality results indicated four factors for this scale. A strong relationship was found between the SF-MPQ-2 total score and other scales (r = 0.55 to 0.85). In reliability analysis, Cronbach’s alpha and ICC were 0.93 and 0.94 for SF-MPQ-2, respectively. Conclusion. The results of this study showed that SF-MPQ-2 has adequate validity and reliability to measure pain in people with Parkinson’s disease.


Hand Therapy ◽  
2020 ◽  
Vol 25 (2) ◽  
pp. 56-62 ◽  
Author(s):  
Erfan Shafiee ◽  
Maryam Farzad ◽  
Joy Macdermid ◽  
Amirreza Smaeel Beygi ◽  
Atefeh Vafaei ◽  
...  

Introduction The Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire is a tool designed for self-assessment of forearm pain and disability in patients with tennis elbow. The aims of this study were to translate and cross-culturally adapt the PRTEE questionnaire into Persian and evaluate its reliability and construct validity. Methods The PRTEE questionnaire was translated into and cross-culturally adapted to Persian in 90 consecutive patients with tennis elbow, according to well-established guidelines. Reliability was tested by means of test–retest and internal consistency. The measurement error was measured by calculating the standard error of measurement. Based on the standard error of measurement, the minimum detectable change was calculated. To evaluate construct and convergent validity, correlation with the PRTEE with the Disabilities of the Arm, Shoulder and Hand questionnaire and Visual analogue scale was used. Results In the process of cross-cultural adaptation, two items (6 and 8) were modified. In item 6, the term “door knob” was changed to “turn a key”, and in the item 8, “cup of coffee” was changed to “cup of milk”. Item-total correlations were greater than 0.55 (ranged from 0.55 to 0.76), internal consistency was high (Cronbach’s alpha, 0.94) and a high intraclass correlation coefficient (0.98) indicated excellent reliability of the P-PRTEE. The standard error of measurement and minimum detectable change were 5.40 and 14.24, respectively. The Persian version of the PRTEE questionnaire (P-PRTEE) shows strong construct and convergent validity ( r values = 0.85, p < 0.05). Conclusions The P-PRTEE is valid and reliable in assessing disability and pain in Persian patients with tennis elbow. The excellent psychometric properties of the P-PRTEE endorse the use of this questionnaire in clinical settings.


2017 ◽  
Vol 30 (5) ◽  
pp. 395 ◽  
Author(s):  
Joana Jesus-Ribeiro ◽  
Elsa Vieira ◽  
Pedro Ferreira ◽  
Cristina Januário ◽  
António Freire

Introduction: Parkinson’s disease has a significant impact in quality of life, which can be assessed with 39-item Parkinson’s Disease Questionnaire and Parkinson’s Disease Quality of Life Questionnaire. This study aimed to evaluate the reliability and validity of these scales in Portuguese patients.Material and Methods: Reliability was assessed through internal consistency (Cronbach’s alpha) and reproducibility (intraclass correlation coefficient). Regarding construct validity, we performed one-way analysis of variance across different groups according to modified Hoehn and Yahr scale. For criterion validity, we compared both scales with each other and with the Short Form 36-item Health Survey.Results: In a total of 100 patients with Parkinson’s disease, Cronbach’s alpha ranged for 39-item Parkinson’s Disease Questionnaire between 0.66 - 0.98, and for Parkinson’s Disease Quality of Life Questionnaire, between 0.78 - 0.98. Intraclass correlation coefficient for 39-item Parkinson’s Disease Questionnaire ranged between 0.49 - 0.96, and for Parkinson’s Disease Quality of Life Questionnaire, ranged between 0.65 - 0.96. Both scales showed, in general, capacity to discriminate differences among patients in the different stages of disease. The scales presented moderate to strong magnitude correlations with some Short Form 36-item Health Survey domains.Discussion: Cronbach’s alpha coefficients for most domains were satisfactory. Overall, it has been demonstrated good reproducibility, as well as construct and criterion validity.Conclusion: The Portuguese versions of both scales showed to be valid and reliable.


2021 ◽  
pp. 1-8
Author(s):  
Bradley McDaniels ◽  
Chun-Lung Lee ◽  
Malachy Bishop

Background: Positive personality resources have demonstrated the ability to positively impact health outcomes. Objective: To examine the psychometric properties of the original Psychological Capital Questionnaire (PCQ-24) in patients with Parkinson’s disease (PD). Methods: A sample of 114 individuals with PD completed the PCQ-24, and via a latent factor modeling framework exploratory and confirmatory factor analyses were conducted to evaluate the psychometric properties in people with PD. Results: Exploratory factor analysis (EFA) revealed that both the efficacy and hope scales were reliable (Cronbach’s alpha = 0.87 and 0.86, respectively) and had statistically acceptable validity with strong factor loadings all above the practical threshold of 0.60. The resilience and optimism scales were also reliable (Cronbach’s alpha = 0.78 and 0.73, respectively) but had only moderately acceptable validity in part due to three reverse-scored items (i.e., No. 13, 20, & 23) with weak factor loadings of 0.26, 0.46, and 0.50, respectively. After excluding these at-risk items, the overall factor loadings for resilience and optimism were significantly improved at the acceptable above 0.60. The CFA results confirm a statistically acceptable model fit for the modified version (only 21-items) of the PCQ in the PD sample. Conclusion: Both EFA and CFA analyses provide statistical evidence supporting the modified PCQ version and demonstrate better test validity and reliability in the PD population. The refined PCQ form is both effectively shorter and psychometrically superior to the original and has promise in investigating health outcomes in people with PD.


2020 ◽  
Vol 9 ◽  
pp. 1754
Author(s):  
Masoumeh Fazeli Tarmazdi ◽  
Zahra Tagharrobi ◽  
Zahra Sooki ◽  
Khadijeh Sharifi

Background: The first step to successful aging planning is to assess the current status using valid instruments. This study aimed to evaluate the psychometric properties of the Persian version of the Successful Aging Inventory (SAI). Materials and Methods: In the first step, SAI. was translated through forward-backward translation, and its face and content validity were qualitatively and quantitatively assessed. For construct validity assessment, 300 elderly were recruited through multi-stage random sampling. Exploratory factor analysis and known-group comparison were used. SAI reliability through internal consistency and stability was assessed using the Cronbach’s alpha values of the inventory and intraclass correlation coefficient (ICC), respectively. The standard error of measurement, smallest detectable change, and floor and ceiling effects were calculated. Results: The impact scores, content validity ratios, and content validity indices of all items were more than 1.5, 0.62, and 0.8, respectively. The scale-level content validity index was 0.94. Factor analysis identified four factors for the inventory, which explained 58.17% of the total variance of the SAI score. SAI mean score among mentally healthy participants was significantly higher (P<0.001). The relative frequencies with the lowest and highest possible scores of SAI were 0 and 3.7%, respectively. The Cronbach’s alpha, ICC, standard error of measurement, and the smallest detectable change of SAI were 0.835, 0.999, ±0.47, and 1.9, respectively. Conclusion: As a valid and reliable instrument, the Persian version of SAI could be used for a successful aging assessment. [GMJ.2020;9:e1754]


Folia Medica ◽  
2013 ◽  
Vol 55 (3-4) ◽  
pp. 56-62 ◽  
Author(s):  
Stefka G. Mantarova ◽  
Irena V. Velcheva ◽  
Spaska O. Georgieva ◽  
Katerina I. Stambolieva

ABSTRACT The last twenty years have witnessed a surge of interest in the autonomic symptoms in Parkinson’s disease (PD) and the possibilities to diagnose and treat them. The specialized questionnaire assessing the autonomic symptoms in Parkinson’s disease (SCOPA-AUT) has been validated and available in English, Dutch and Spanish. In this study we aim at evaluating the validity, reliability and applicability of the Bulgarian version of SCOPAAUT (SCOPA-AUT-BG ). PATIENTS AND METHODS: The study included 55 patients with idiopathic PD (mean age 64.4 ± 8.9 yrs), and 40 healthy controls (mean age 58.5 ± 9.4 yrs). Clinical severity and disease stage were assessed by United Parkinson’s disease rating scale (UPRDS) and Hoen and Yahr (H&Y). Thirty-two of the PD patients completed SCOPA-AUT-BG again after a 7-day interval. Questionnaire reliability was analyzed by determining the internal consistency, homogeneity, discriminatory and construct validity and test-retest reliability. RESULTS: Analyses showed good internal consistency of the summary evaluation of SCOPAAUT- BG (coefficient alpha of Cronbach = 0.79), which indicates the high reliability of the questionnaire. The lowest Cronbach’s alpha coefficient (0.53) was found for the subscale “cardiovascular functions”. A dominant role belongs to the subscales for gastrointestinal and urinary functions (Cronbach’s Alpha > 0.7), where a significantly high correlation of PD with the UPDRS scale was observed. We found high test-retest reliability based on the responses associated with dysfunction of the gastrointestinal, urinary, thermoregulatory and pupillary autonomic systems. The correlation of the results of SCOPA-AUT-BG with UPDRS is higher than that with H&Y, and the construct validity is high except for the cardiovascular and pupillomotor functions subscales. CONCLUSION: The results of this study show that SCOPA-AUT-BG is a valid and reliable specialized questionnaire to evaluate autonomic function in patients with Parkinson’s disease. Using it allows for more detailed clinical evaluation of these patients and justifies the need to refer them to specialized examination of autonomic functions.


2018 ◽  
Vol 6 ◽  
pp. 205031211775203 ◽  
Author(s):  
Synne Garder Pedersen ◽  
Guri Anita Heiberg ◽  
Jørgen Feldbæk Nielsen ◽  
Oddgeir Friborg ◽  
Henriette Holm Stabel ◽  
...  

Background: There is a paucity of stroke-specific instruments to assess health-related quality of life in the Norwegian language. The objective was to examine the validity and reliability of a Norwegian version of the 12-domain Stroke-Specific Quality of Life scale. Methods: A total of 125 stroke survivors were prospectively recruited. Questionnaires were administered at 3 months; 36 test–retests were performed at 12 months post stroke. The translation was conducted according to guidelines. The internal consistency was assessed with Cronbach’s alpha; convergent validity, with item-to-subscale correlations; and test–retest, with Spearman’s correlations. Scaling validity was explored by calculating both floor and ceiling effects. A priori hypotheses regarding the associations between the Stroke-Specific Quality of Life domain scores and scores of established measures were tested. Standard error of measurement was assessed. Results: The Norwegian version revealed no major changes in back translations. The internal consistency values of the domains were Cronbach’s alpha = 0.79–0.93. Rates of missing items were small, and the item-to-subscale correlation coefficients supported convergent validity (0.48–0.87). The observed floor effects were generally small, whereas the ceiling effects had moderate or high values (16%–63%). Test–retest reliability indicated stability in most domains, with Spearman’s rho = 0.67–0.94 (all p < 0.001), whereas the rho was 0.35 (p < 0.05) for the ‘Vision’ domain. Hypothesis testing supported the construct validity of the scale. Standard error of measurement values for each domain were generated to indicate the required magnitudes of detectable change. Conclusions: The Norwegian version of the Stroke-Specific Quality of Life scale is a reliable and valid instrument with good psychometric properties. It is suited for use in health research as well as in individual assessments of persons with stroke.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Gill Nelson ◽  
Ntombizodwa Ndlovu ◽  
Nicola Christofides ◽  
Tintswalo M. Hlungwani ◽  
Irene Faust ◽  
...  

Background. There are very few epidemiological studies investigating Parkinson’s disease (PD) in Africa. The hundreds of local languages and dialects make traditional screening and clinical evaluation tools difficult to use. Objective. The objective of the study was to validate two commonly used PD questionnaires in an African population. Methods. The PD Screening Questionnaire (PDSQ) and Parkinson’s Disease Questionnaire (PDQ-39) were modified and translated into Afrikaans, Setswana, and isiZulu and administered to a sample of healthy local residents. We assessed the internal consistencies and cluster characteristics of the questionnaires, using a Cronbach’s alpha test and exploratory factor analysis. The questionnaires were then administered to a population-based sample of 416 research participants. We evaluated the correlations between the questionnaires and both a timed motor task and the Unified Parkinson’s Disease Rating Scale motor subsection 3 (UPDRS3), using locally weighted scatterplot smoothing (LOWESS) regression analysis and Spearman’s rank correlation. Results. Both questionnaires had high overall internal consistency (Cronbach’s alpha = 0.86 and 0.95, respectively). The modified PDQ-39 had evidence of five subscales, with Factor 1 explaining 57% and Factor 2 explaining 14%, of the variance in responses. The PDSQ and PDQ-39 scores were correlated with the UPDRS3 score (ρ = 0.35, P<0.001; and ρ = 0.28, P<0.001, respectively). Conclusion. The translated PDSQ and PDQ-39 questionnaires demonstrated high internal consistency and correlations with clinical severity of parkinsonism and a timed motor task, suggesting that they are valid tools for field-based epidemiological studies.


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Zoe Morou ◽  
Georgios N. Lyrakos ◽  
Nikolaos G. Papadopoulos ◽  
Nikolaos Douladiris ◽  
Athina Tatsioni ◽  
...  

The aim of the study is to determine the reliability and validity of the Greek version of the Food Allergy Quality of life Questionnaire- Child Form (FAQLQ-CF). After linguistic validation, the Greek FAQLQCF, Food Allergy Independent Measure (FAIM) and Pediatric Quality of Life Inventory (PedsQL™) were used by a physician to interview children diagnosed with food allergy and aged 8-12 via telephone. Cronbach’s alpha was used to evaluate reliability, and factor analysis to assess construct validity. The correlation between FAQLQ-CF and FAIM was moderate (rho=0.509, P&lt;0.001) and internal consistency was strong (Cronbach’s alpha 0.905). FAQLQ-CF discriminated well each question’s contribution to children’s quality of life deterioration (32- 80%), each child’s quality of life (17-89%), children differing in doing things with others (total score 3.55 vs 2.57, difference =0.98 &gt; minimal clinical importance difference = 0.5; P&lt;0.001), but not children differing in reporting anaphylaxis. The total FAQLQ-CF score correlated with the total PedsQL™ score and with the score of one of PedsQL™ subscales, demonstrating convergent validity. Factor analysis uncovered an underlying structure of four factors, explaining 50% of the variance. We can conclude that Greek FAQLQ-CF is a reliable, valid, discriminant tool for interviewing food allergic children aged 8- 12, detecting those in need for immediate care.


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