scholarly journals A Systematic Review of the Effect of Oral Rinsing with H2O2 on Clinical and Microbiological Parameters Related to Plaque, Gingivitis, and Microbes

2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Francisco Wilker Mustafa Gomes Muniz ◽  
Juliano Cavagni ◽  
Gerson Pedro José Langa ◽  
Bernal Stewart ◽  
Zilson Malheiros ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hydrogen Peroxide ◽  
Dental Plaque ◽  
Oral Bacteria ◽  
Cochrane Library ◽  
Oral Microbiota ◽  
Supporting Evidence ◽  
Gingival Inflammation ◽  
Mouth Rinses ◽  
Microbiological Parameters

Background. Hydrogen peroxide (H2O2) has been used for more than a century clinically to control plaque and gingival inflammation, with unclear supporting evidence. Aim. The aim of the present systematic review of the literature is to assess the effect of mouth rinses with H2O2 on dental plaque, gingival inflammation, and oral microorganisms. Methods. Five databases (PubMed, Scopus, Embase, Cochrane Library, and Web of Science) were searched with the following focused question: what is the effect of hydrogen peroxide, in comparison to chlorhexidine or to a placebo solution, in oral microbiota control, dental plaque, and gingival inflammatory outcomes? Two independent examiners retrieved the articles and evaluated the evidence. Results. The majority of included studies were performed with 1.5% H2O2. Results related to plaque accumulation generally demonstrate a slightly better effect of H2O2 as compared to placebo mouth rinses, however with a lower performance as compared to chlorhexidine. In terms of gingival inflammation, H2O2 performs better than placebo and more clearly demonstrates an anti-inflammation effect. No studies evaluated the effect of H2O2 against viruses or fungi. In terms of bacteria, H2O2 demonstrates an antibacterial effect. Conclusion. Rinsing with H2O2 has the potential to affect plaque, gingivitis, and oral bacteria, as compared to placebo. However, the antibacterial results are not comparable to the performance of chlorhexidine.

Effect of herbal mouthrinses on dental plaque formation and gingival inflammation: A systematic review

Oral Diseases ◽  
2019 ◽  
Author(s):  
Samantha Simoni Santi ◽  
Maísa Casarin ◽  
Alessandra Pascotini Grellmann ◽  
Leandro Chambrone ◽  
Fabricio Batistin Zanatta
Keyword(s):  
Systematic Review ◽  
Dental Plaque ◽  
Plaque Formation ◽  
Gingival Inflammation

scholarly journals Effect of Amoxicillin Use on Oral Microbiota in Young Children

2004 ◽  
Vol 48 (8) ◽  
pp. 2883-2887 ◽  
Author(s):  
D. Ready ◽  
H. Lancaster ◽  
F. Qureshi ◽  
R. Bedi ◽  
P. Mullany ◽  
...  
Keyword(s):  
Young Children ◽  
Oral Cavity ◽  
Dental Plaque ◽  
Antibiotic Use ◽  
Oral Bacteria ◽  
Resistant Bacteria ◽  
Oral Microbiota ◽  
Sample Collection ◽  
Median Percentage ◽  
Resistance To Penicillin

ABSTRACT Dental plaque samples from 40 children were screened for the presence of bacteria resistant to amoxicillin. Fifteen children had used amoxicillin and 25 had not used any antibiotic in the 3 months prior to sample collection. All (100%) of the children harbored amoxicillin-resistant oral bacteria. The median percentage of the total cultivable oral microbiota resistant to amoxicillin was 2.4% (range, 0.1 to 14.3%) in children without amoxicillin use and 10.9% (range, 0.8 to 97.3%) in children with amoxicillin use, with the latter value being significantly higher (P < 0.01). A total of 224 amoxicillin-resistant bacteria were isolated and comprised three main genera: Haemophilus spp., Streptococcus spp., and Veillonella spp. The biodiversity of the amoxicillin-resistant microbiota was similar among the isolates from children with and without previous antibiotic use. The amoxicillin MIC at which 90% of the isolates were inhibited for isolates from children who had used amoxicillin in the previous 3 months was higher (64 mg liter−1) than that obtained for the isolates from subjects who had not used antibiotics (16 mg liter−1). The majority of the amoxicillin-resistant isolates (65%) were also resistant to at least one of the three antibiotics tested (penicillin, erythromycin, and tetracycline), with resistance to penicillin (51% of isolates) being the most frequently encountered. However, significantly more (P < 0.05) of the amoxicillin-resistant isolates from subjects with previous amoxicillin use were also resistant to erythromycin. This study has demonstrated that a diverse collection of amoxicillin-resistant bacteria is present in the oral cavity and that the number, proportions, MICs, and resistance to erythromycin can significantly increase with amoxicillin use.

scholarly journals Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review

2021 ◽  
Vol 2 ◽  
Author(s):  
Alexandre Henrique dos Reis-Prado ◽  
Isadora Rodrigues Grossi ◽  
Hebertt Gonzaga dos Santos Chaves ◽  
Carolina Bosso André ◽  
Luís Fernando dos Santos Alves Morgan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hydrogen Peroxide ◽  
Dental Pulp ◽  
Cochrane Library ◽  
Dental Pulp Cells ◽  
Pulp Tissue ◽  
Alp Activity ◽  
Dental Hard Tissues ◽  
Pulp Cells

Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on the process of mineralization of the pulp tissue.Methods: Only in vitro studies evaluating the influence of hydrogen peroxide (HP) on mineralization in dental pulp cells were included. Studies without a non-bleached control group or cells after co-treatment with a bleaching agent other than HP and/or carbamide peroxide were excluded. The primary outcomes evaluated were alkaline phosphatase (ALP) activity and mineralized nodule deposition. The mineralization markers analysis in dental pulp cells and the cell viability were considered secondary outcomes. Two independent authors conducted a systematic search (PubMed/MEDLINE, Scopus, Embase, Cochrane Library, and OpenGrey until January 2021) with no language restrictions and performed data extraction. The quality assessment was appraised according to a modified Joanna Briggs Institute critical appraisal checklist.Results: The search resulted in 473 studies, and 11 were considered eligible. Overall, a reduction in the process of mineralization was observed among pulp cells after bleaching. A reduction in the ALP activity was reported in the mostly bleached groups using different protocols and analysis periods of nine studies. Regarding mineralized nodule deposition, 6 studies reported a significant reduction from 7 to 21 days among bleached groups. Of those three studies that investigated other mineralization markers, two found a reduction in the expression of dentin matrix acidic phosphoprotein (DMP)-1, dentin sialophosphoprotein (DSPP), and matrix extracellular phosphoglycoprotein (MEPE) among some bleaching gel concentrations. In contrast, one study showed a greater expression of osteopontin (OPN) and osteocalcin (OCN) in 100 μmol/L HP after 5 or 10 min of exposure, and another study showed significant induction of DSPP in concentrations of up to 0.5 mmol/L HP.Conclusion: Especially, high concentrations of bleaching gel reduce the potential of mineralization in pulp cells in in vitro studies; however, different HP concentrations, bleaching protocols, and analysis periods can influence this outcome.

scholarly journals The oral and gut microbiota: beyond a short communication

2021 ◽  
pp. 405-411
Author(s):  
Sabino CECI ◽  
Pula BERATE ◽  
Sebastian CANDREA ◽  
Anida-Maria BABTAN ◽  
Daniela AZZOLLINI ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Gut Microbiota ◽  
Oral Bacteria ◽  
The Body ◽  
Cochrane Library ◽  
Oral Microbiota ◽  
Oral Diseases ◽  
Philosophical Approach ◽  
Gut Dysbiosis ◽  
Inflammatory Bowel

Introduction. The current treatment and prevention of oral disorders, dental caries, periodontal and gum diseases, follow a very non-specific control of plaque as the main causative factor. The main therapeutically approach is carried out on the sole perspective to keep the levels of oral bacteria in an acceptable range compatible with one-way vision of oral-mouth health, as something completely separated from a systemic microbial homeostasis (dysbiosis) concomitant present in the gut. A sealed compartmental view which sees separate and incommunicable responses to a specific condition without considering the presence of interacting confounding factors can negatively influence the diagnosis a diseases and of course its progression. A general non-specific antimicrobial with more general antiplaque therapy based mainly on oral care products together with surgery interventions represent at the moment the only mechanical responses in treating oral diseases. Material and method. The present paper is a narrative review concening interractions between oral and gut microbiota, with a focus on the interdisciplinary approach in antimicrobial treatment. Pubmed, Cochrane Library database were used for searching engines. Key words used were as follows: “inflammatory bowel syndrome (IBS)”, “ulcerative colitis”, “oral dysbiosis”, “gut dysbiosis”, “probiotics”, “periodontitis”. Results and discussions. Literature research showed that there are few issues to be discussed the ever increasing resistance to antibiotics, the high consumption of industrial food and sugars and their negatively effect on gut and oral microbiota. There is a need to highlight and develop a novel philosophical approach in the treatments for oral diseases that will necessarily involve non-conventional antimicrobial solutions. Such approaches should preferably reduce the consumption of both intestinal and oral microbiota, that are intimately connected and host approximately well over 1000 different species of bacteria at 108–109 bacteria per mL of mucous and saliva. Preventive approaches based upon the restoration of the microbial ecological balance, rather than elimination of the disease associated species, have been proposed. Conclusions. Having both oral-gut microbiota screened is an essential moment that influence the healthy immune modulatory and regenerative capacity of the body and, the new proposed formula integrates a wider screen on the patients where oral condition is strictly evaluated together with gut screen; therefore any proposed treatment will be inevitably sustained by the use of prebiotics and probiotics to promote health-associated bacterial growth. Keywords: inflammatory bowel syndrome (IBS), ulcerative colitis, oral dysbiosis, gut dysbiosis, probiotics, periodontitis,

scholarly journals Efficacy of propolis-based mouthwashes on dental plaque and gingival inflammation: a systematic review

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Esam Halboub ◽  
Sadeq A. Al-Maweri ◽  
Mohammed Al-Wesabi ◽  
Ahlam Al-Kamel ◽  
Anas Shamala ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Plaque ◽  
Gingival Inflammation

scholarly journals Comparative Evaluation of the Effect of Chlorhexidine Gluconate, Raw Propolis and Hydrogen Peroxide on Dental Plaque and Gingival Inflammation

2018 ◽  
Vol 2 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Surbhi Porwal ◽  
Aditi Mathur ◽  
Neema Shetty ◽  
Balaji Manohar ◽  
Barkha Makhijani ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Chlorhexidine Gluconate ◽  
Plaque Index ◽  
Tooth Surface ◽  
Gingival Index ◽  
Gingival Inflammation ◽  
Group I ◽  
Mouth Wash

Background: Plaque is the soft deposit that forms the biofilm consisting of microorganisms adhering to the tooth surface and is proved beyond doubt to be the initiator of gingival and periodontal disease. Plaque control is the mainstay in periodontal disease. Aim: To compare the effect of 0.2% chlorhexidine gluconate, raw propolis and 3% hydrogen peroxide mouthwash on dental plaque and gingival inflammation. Materials and Methods: Thirty subjects in the age group of 20-40 years were enrolled in the study. Plaque index and Modified Gingival Index were recorded at baseline and oral prophylaxis was performed. Subjects were then randomly divided into three groups (n=10) and were asked to rinse with 10ml mouthwash twice daily for 15 days. Group I received 0.2% chlorhexidine gluconate mouth wash, Group II raw propolis diluted with distilled water (1:1), and Group III 3% hydrogen peroxide (1:1) mouthwash. Subjects were recalled on 7 day and 28 day for re-evaluation and recording plaque index and modified gingival index. Statistical analysis was done to evaluate the efficacy of all the three mouthwashes. Results: The results showed that all the three mouthwashes were effective in reducing plaque and gingival inflammation. Chlorhexidine gluconate 0.2% showed to be the most effective in reduction of dental plaque. Propolis was observed to be the most effective in reducing gingival inflammation over a period of 28 days. Conclusion: Propolis can be effectively used as a mouthwash without any potential side effects as an alternative to chlorhexidine mouthwash in reducing gingival inflammation.

Effect of Bleaching Gel Concentration on Tooth Color and Sensitivity: A Systematic Review and Meta-analysis

2020 ◽  
Vol 45 (3) ◽  
pp. 265-275 ◽  
Author(s):  
MMA Pontes ◽  
JML Gomes ◽  
CAA Lemos ◽  
RS Leão ◽  
SLD Moraes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hydrogen Peroxide ◽  
Systematic Reviews ◽  
Color Change ◽  
Meta Analysis ◽  
Cochrane Library ◽  
High Concentration ◽  
Tooth Sensitivity ◽  
Bleaching Procedure ◽  
Significant Difference

SUMMARY Objective: The aim of this systematic review and meta-analysis was to evaluate a high concentration of hydrogen peroxide (35%) regarding tooth sensitivity and color change in tooth bleaching in comparison to low concentrations (6% to 20%). Methods and Materials: This review was conducted using the criteria of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and is registered on the Prospective Register of Systematic Reviews (CRD42017064493). The PICO question was “Does a concentration of hydrogen peroxide ≥35% using in-office bleaching procedure contribute to greater tooth sensitivity?” A search was made in PubMed/MEDLINE, Scopus, and the Cochrane Library. Results: Fourteen studies were selected for the qualitative analysis and seven for quantitative analysis. A total of 649 patients were evaluated (mean age: 36.32 years; range: 13.9 to 31 years), and the follow-up period ranged from one week to 12 months. The meta-analysis demonstrated that tooth sensitivity was higher in the patients submitted to treatment involving a high concentration of hydrogen peroxide (0.67; 95% confidence interval [CI]: 0.44 to 1.03; p=0.04; I2: 56%), and a significant difference was found regarding objective color ΔE (1.53; 95% CI: 2.99 to 0.08; p&lt;0.0001; I2: 82%) but no significant difference was found regarding subjective color ΔSGU (0.24; CI: 0.75 to 1.23; p&lt;0.00001; I2: 89%). Conclusions: This study indicated that a lower concentration of hydrogen peroxide causes less tooth sensitivity and better effectiveness in objective color change (ΔE); however, there is no difference between them related to subjective color (ΔSGU).

scholarly journals Oral Cavity as an Extragastric Reservoir of Helicobacter pylori

2014 ◽  
Vol 2014 ◽  
pp. 1-16 ◽  
Author(s):  
Arwa Al Sayed ◽  
Pradeep S. Anand ◽  
Kavitha P. Kamath ◽  
Shankargouda Patil ◽  
R. S. Preethanath ◽  
...  
Keyword(s):  
Systematic Review ◽  
Helicobacter Pylori ◽  
Oral Cavity ◽  
Oral Hygiene ◽  
Dental Plaque ◽  
Web Of Science ◽  
Cochrane Library ◽  
H Pylori ◽  
The Impact

Background. Several studies were reported on the prevalence, and relationship between the existence of Helicobacter pylori (H. pylori) in oral cavity and in stomach of patients. The purpose of this study was to systematically review the existing literature on the presence of H. pylori in the oral cavity and its link to gastric infection, the existence of coinfection, and the impact of anti-H. pylori therapy on the dental plaque and vice versa. Method. Two authors independently searched the Medline, EMBASE, Cochrane Library, Web of Science, Google Scholar, and Scopus databases for relevant studies. The articles were analyzed critically and all qualified studies were included. The search was carried out by using a combined text and the MeSH search strategies: using the key words Helicobacter, Helicobacter pylori, and H. pylori in combination with dental plaque, periodontitis, and oral hygiene. Results. The data was presented in 8 tables and each topic separately discussed. Conclusion. Based on the systematic review of the available literature on H. pylori infection and its presence in the oral cavity, it can be concluded that dental plaque can act as a reservoir, and proper oral hygiene maintenance is essential to prevent reinfection. Due to the diversified methods and population groups involved in the available literature, no concrete evidence can be laid down. Further studies are necessary to establish the role of H. pylori in the oral cavity and its eradication on preventing the gastroduodenal infection.

Sign in / Sign up

Export Citation Format

Share Document