scholarly journals Hepatocellular Carcinoma in a 24-Year-Old Female with Beckwith–Wiedemann Syndrome: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Carolyn G. Ahlers ◽  
Quoc-Huy Trinh ◽  
Martin Montenovo

In this report, the case of a 24-year-old female with Beckwith–Wiedemann Syndrome (BWS) who was diagnosed with well-differentiated hepatocellular carcinoma (HCC) is described. While BWS has been associated with childhood embryonal tumors, most commonly Wilms tumors and hepatoblastomas, this is the first case report to describe HCC in an adult with BWS. Although HCC typically occurs in elderly adults or those with underlying liver disease, in this case, we show that HCC can occur in a young adult with BWS without any underlying liver disease.

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
M. I. Montenovo ◽  
F. G. Jalikis ◽  
M. Yeh ◽  
J. D. Reyes

We report a case of hepatic adenoma progression to carcinoma in the setting of hepatoportal sclerosis in an HIV+ patient and provide a review of the scarce literature regarding hepatoportal sclerosis in HIV patients. We describe the clinical presentation, diagnostic workup, and management. This is the first case report in the literature of progression of hepatic adenoma to carcinoma in hepatoportal sclerosis in an HIV patient. This case also highlights the broad differential diagnosis that should always be included in the study of any liver disease in this patient population, including the performance of invasive and aggressive tests to arrive at the final diagnosis.


1993 ◽  
Vol 79 (2) ◽  
pp. 137-140 ◽  
Author(s):  
Alessandro Mazzocchi ◽  
Maria P. Foschini ◽  
Franco Marconi ◽  
Vincenzo Eusebi

Introduction Kasabach-Merritt syndrome is characterized by the association of a consumptive thrombohemorrhagic disorder and angioma occurring usually in children. In the present study, a case of Kasabach-Merritt syndrome associated to an angiosarcoma of the breast is reported. Clinical History The tumor together with the thrombohemorrhagic disorder manifested in a 28-year-old woman. The patient underwent mastectomy. The tumor recurred in the same site 2 years later. The patient died of severe anemia 8 years after the first appearance of the angiosarcoma. Material and Methods Tissues were formalin fixed and paraffin embedded; in addition, selected sections were immunohistochemically stained. Results and Conclusions A well-differentiated angiosarcoma was visible throughout the removed organ. A review of the literature showed that only 6 cases of Kasabach-Merritt syndrome associated to malignant vascular tumors have been previously reported. All these 6 cases occurred in adult patients. On the contrary, Kasabach-Merritt syndrome associated to benign vascular tumors affects children. This is the first case occurring in the breast.


2020 ◽  
Vol 3 (S 01) ◽  
pp. S73-S76
Author(s):  
Gilad Borisovsky ◽  
Daniel A. Goldstein ◽  
Noa Eliakim-Raz ◽  
Shlomit R. Tamir

AbstractPseudocirrhosis is the occurrence of capsular retraction in patients with metastatic liver disease, usually of breast origin. It usually appears in these patients following chemotherapy and may result from shrinkage of the tumor, with scarring and nodular regeneration. In this article, we describe the first case of pseudocirrhosis, following treatment of transitional cell carcinoma metastatic to the liver. Portal vein thrombosis, a rare complication in pseudocirrhosis, was also detected in this patient.


2021 ◽  
Vol 16 (3) ◽  
pp. 550-554
Author(s):  
Moheieldin M Abouzied ◽  
Ahmed Fathala ◽  
Ahmad AlMuhaideb ◽  
Hadeel Almanea ◽  
Abdulaziz S Al-Sugair ◽  
...  

2019 ◽  
Vol 48 (10) ◽  
pp. 1623-1628
Author(s):  
Adriana C. Moreira ◽  
David I. Suster ◽  
Sterling Ellis Eide ◽  
Daniel I. Rosenthal ◽  
Connie Y. Chang

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Samin Alavi ◽  
Maryam Ebadi ◽  
Alireza Jenabzadeh ◽  
M. T. Arzanian ◽  
Sh. Shamsian

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.


2003 ◽  
Vol 90 (1) ◽  
pp. 23-28 ◽  
Author(s):  
T. Itamoto ◽  
K. Katayama ◽  
H. Nakahara ◽  
H. Tashiro ◽  
T. Asahara

2012 ◽  
Vol 32 (02) ◽  
pp. 186-192
Author(s):  
Neil Parikh ◽  
Valerie Martel-Laferriere ◽  
Xuchen Zhang ◽  
Douglas Dieterich ◽  
Maria Fiel ◽  
...  

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