scholarly journals Promotion of Bone Formation by Red Yeast Rice in Experimental Animals: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Bin Wu ◽  
Jie-Feng Huang ◽  
Bang-Jian He ◽  
Chen-Wei Huang ◽  
Jian-Hua Lu
Keyword(s):  
Bone Mineral Density ◽  
Bone Formation ◽  
Bone Mineral ◽  
Meta Analysis ◽  
Red Yeast Rice ◽  
Osteoblast Proliferation ◽  
Mineral Density ◽  
Treatment Of Osteoporosis ◽  
Experimental Animals ◽  
Red Yeast

Objective. To systematically evaluate the effects of red yeast rice (RYR) and its extract on bone formation in experimental animals and to provide reference data for clinical research on the treatment of osteoporosis. Methods. Chinese and English language databases, including Web of Science, PubMed, the Cochrane Library, Elsevier, Google Scholar, SpringerLink, Embase, China National Knowledge Infrastructure (CNKI), Weipu Chinese Sci-tech periodical full-text database (VIP), and Wanfang Data Knowledge Service Platform (Wanfang), were searched from their establishment to February 2020 using the following terms: “hongqu,” “red yeast rice,” “Monascus purpureus-fermented rice,” “bone mineral density,” “osteoblast,” “osteoporosis,” and “animal models.” After excluding nonrelevant articles, Review Manager 5.2 was used to evaluate article quality and to analyze the data. Outcome indicators included bone mineral density (BMD), osteoblast proliferation, and the expression of alkaline phosphatase (ALP). Results. A total of 11 randomized controlled trials were included in the meta-analysis, all of which were animal studies. Six studies included data on BMD, five on osteoblast proliferation, and six on the expression of ALP. The results of the meta-analysis showed that RYR can significantly improve BMD (standardized mean difference SMD=3.12, 95% confidence interval (CI) 1.41 to 4.83, P=0.0003), promote osteoblast proliferation (SMD=1.64, 95% CI 1.04 to 2.23, P<0.00001), and increase ALP expression in rats (SMD=1.25, 95% CI 0.69 to 1.80, P<0.00001). Conclusions. RYR can promote bone formation in experimental animals and may be useful for the treatment of osteoporosis.

scholarly journals Effects of Recreational Small-Sided Soccer Games on Bone Mineral Density in Untrained Adults: A Systematic Review and Meta-Analysis

Healthcare ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 457
Author(s):  
Filipe Manuel Clemente ◽  
Rodrigo Ramirez-Campillo ◽  
Hugo Sarmento ◽  
Daniel Castillo ◽  
Javier Raya-González ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Systematic Review ◽  
Active Control ◽  
Bone Mineral ◽  
Meta Analysis ◽  
Adult Population ◽  
Noncommunicable Disease ◽  
Lower Limbs ◽  
Mineral Density ◽  
Control Groups

This systematic review with meta-analysis was conducted to assess the effects of small-sided games (SSG)-based training programs on bone mineral density (BMD) in untrained adults. The data sources utilized were Cochrane, Embase, Medline (PubMed), Scopus, SPORTDiscus, and Web of Science. The study eligibility criteria were: (i) untrained adults (>18 years old) of any sex, with or without a noncommunicable disease; (ii) SSG-based programs with a minimum duration of four weeks and no restrictions regarding frequency (number of sessions per week); (iii) passive or active control groups; (iv) pre-post values of BMD; (v) only randomized controlled trials; and (vi) only original and full-text studies written in English. The database search initially yielded 374 titles. From those, nine articles were eligible for the systematic review and meta-analysis. The age of included population varied from a minimum of 20 and a maximum of 71 years old. Non-significant differences between SSG and passive and active control groups on total BMD (ES = 0.14; p = 0.405 and ES = 0.28; p = 0.05, respectively). Meanwhile, significant differences in favor of SSGs vs. passive and control groups were detected, evidencing an improvement of BMD in lower limbs of the adult population for both sexes (ES = 0.26; p = 0.05 and ES = 0.28; p = 0.156, respectively). As conclusions, SSGs can be used as a non-pharmacological alternative to increase the BMD in the lower limbs despite having no significant impact on total body BMD. Careful generalization should be done of the level of heterogeneity.

scholarly journals Retraction Note: Associations between VDR Gene Polymorphisms and Osteoporosis Risk and Bone Mineral Density in Postmenopausal Women: A systematic review and Meta-Analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Liang Zhang ◽  
Xin Yin ◽  
Jingcheng Wang ◽  
Daolinag Xu ◽  
Yongxiang Wang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Systematic Review ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Mineral Density ◽  
Vdr Gene ◽  
Vdr Gene Polymorphisms ◽  
Osteoporosis Risk

Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-021-88654-1.

scholarly journals Teriparatide Increases Bone Formation and Bone Mineral Density in Adult Women With Anorexia Nervosa

2014 ◽  
Vol 99 (4) ◽  
pp. 1322-1329 ◽  
Author(s):  
Pouneh K. Fazeli ◽  
Irene S. Wang ◽  
Karen K. Miller ◽  
David B. Herzog ◽  
Madhusmita Misra ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Anorexia Nervosa ◽  
Bone Formation ◽  
Bone Mineral ◽  
Adult Women ◽  
Mineral Density
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